General Information of Probe

Probe ID
LDPC0601
Probe Name
C382
Synonyms
Z4282859725
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 354.4
Lipid-water partition coefficient (xlogp) 2.8
Rotatable Bond Count (rotbonds) 9
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C18H18N4O2S
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-[3-(1,3-thiazol-4-ylmethoxy)phenyl]propanamide
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)NC2=CC(=CC=C2)OCC3=CSC=N3
InChI
InChI=1S/C18H18N4O2S/c1-2-3-8-18(21-22-18)9-7-17(23)20-14-5-4-6-16(10-14)24-11-15-12-25-13-19-15/h1,4-6,10,12-13H,3,7-9,11H2,(H,20,23)
InChIKey
DJGNDLVZFABNLI-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

117 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 18.77  LDD2041 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 11.39  LDD2041 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 10.78  LDD2041 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 12.55  LDD2041 
Acyl-CoA 6-desaturase (FADS2) LDTP01699 9.78  LDD2041 
Acyl-protein thioesterase 2 (LYPLA2) LDTP01573 10.34  LDD2041 
Adenosine deaminase (ADA) LDTP01803 99.73  LDD2041 
ADP-dependent glucokinase (ADPGK) LDTP11127 22.94  LDD2041 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 18.25  LDD2041 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 10.78  LDD2041 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 10.20  LDD2041 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 11.31  LDD2041 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 10.34  LDD2041 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 20.68  LDD2041 
Calcium-independent phospholipase A2-gamma (PNPLA8) LDTP12318 8.94  LDD2041 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 17.88  LDD2041 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 10.85  LDD2041 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 24.25  LDD2041 
Catechol O-methyltransferase (COMT) LDTP03145 11.71  LDD2041 
Ceramide synthase 1 (CERS1) LDTP03394 15.24  LDD2041 
Ceramide synthase 2 (CERS2) LDTP10329 26.91  LDD2041 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 9.92  LDD2041 
Choline kinase alpha (CHKA) LDTP03787 9.71  LDD2041 
COP9 signalosome complex subunit 6 (COPS6) LDTP07966 10.48  LDD2041 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 26.54  LDD2041 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 24.08  LDD2041 
Cytochrome b5 type B (CYB5B) LDTP00697 31.12  LDD2041 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 39.67  LDD2041 
DCN1-like protein 4 (DCUN1D4) LDTP09799 24.93  LDD2041 
DCN1-like protein 5 (DCUN1D5) LDTP11199 8.82  LDD2041 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 8.88  LDD2041 
Delta(24)-sterol reductase (DHCR24) LDTP06375 9.71  LDD2041 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 9.71  LDD2041 
Dihydrofolate reductase (DHFR) LDTP01769 11.08  LDD2041 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 21.11  LDD2041 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 11.16  LDD2041 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 13.45  LDD2041 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 14.72  LDD2041 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 29.04  LDD2041 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 12.30  LDD2041 
Epoxide hydrolase 1 (EPHX1) LDTP02175 10.41  LDD2041 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 8.94  LDD2041 
Gamma-adducin (ADD3) LDTP13204 9.78  LDD2041 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 10.70  LDD2041 
Heme A synthase COX15 (COX15) LDTP07931 9.92  LDD2041 
Heme oxygenase 1 (HMOX1) LDTP02359 22.01  LDD2041 
Heme oxygenase 2 (HMOX2) LDTP03540 52.35  LDD2041 
Histone-lysine N-methyltransferase 2A (KMT2A) LDTP05396 12.91  LDD2041 
Holocytochrome c-type synthase (HCCS) LDTP04581 9.65  LDD2041 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 14.42  LDD2041 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 17.03  LDD2041 
L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) LDTP12105 8.94  LDD2041 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 22.16  LDD2041 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 15.89  LDD2041 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 48.50  LDD2041 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 22.32  LDD2041 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 9.65  LDD2041 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 11.96  LDD2041 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 12.38  LDD2041 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 9.06  LDD2041 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 12.73  LDD2041 
Lysosomal protective protein (CTSA) LDTP02505 9.85  LDD2041 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 10.20  LDD2041 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 35.51  LDD2041 
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B) LDTP01004 9.51  LDD2041 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 33.36  LDD2041 
NAD kinase 2, mitochondrial (NADK2) LDTP06839 8.94  LDD2041 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 13.27  LDD2041 
NAD-capped RNA hydrolase NUDT12 (NUDT12) LDTP11081 13.55  LDD2041 
NAD-dependent protein deacetylase sirtuin-2 (SIRT2) LDTP08598 8.69  LDD2041 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 11.00  LDD2041 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 56.49  LDD2041 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 27.47  LDD2041 
NADH dehydrogenase 1 beta subcomplex subunit 4 (NDUFB4) LDTP01514 9.71  LDD2041 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 10.85  LDD2041 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 16.34  LDD2041 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 31.78  LDD2041 
NADPH--cytochrome P450 reductase (POR) LDTP02848 8.82  LDD2041 
Paladin (PALD1) LDTP16235 21.56  LDD2041 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 15.78  LDD2041 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 13.18  LDD2041 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 14.83  LDD2041 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 8.75  LDD2041 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 16.80  LDD2041 
Phospholipase A2 group XV (PLA2G15) LDTP09088 10.20  LDD2041 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 9.19  LDD2041 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 20.97  LDD2041 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 8.57  LDD2041 
Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) LDTP02679 8.88  LDD2041 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 9.32  LDD2041 
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 9.00  LDD2041 
Protein O-GlcNAcase (OGA) LDTP00988 10.48  LDD2041 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 26.54  LDD2041 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 13.83  LDD2041 
Ras-related protein Rab-24 (RAB24) LDTP10020 9.51  LDD2041 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 21.71  LDD2041 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 13.83  LDD2041 
Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B) LDTP07989 12.55  LDD2041 
Ribosomal protein S6 kinase alpha-1 (RPS6KA1) LDTP06384 10.20  LDD2041 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 12.91  LDD2041 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 14.42  LDD2041 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 8.63  LDD2041 
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PPP2R5E) LDTP06546 9.13  LDD2041 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 12.47  LDD2041 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 10.85  LDD2041 
Squalene monooxygenase (SQLE) LDTP06142 10.56  LDD2041 
Squalene synthase (FDFT1) LDTP03842 18.00  LDD2041 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 28.05  LDD2041 
Sulfotransferase 2A1 (SULT2A1) LDTP05493 9.32  LDD2041 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 15.03  LDD2041 
Trimethyllysine dioxygenase, mitochondrial (TMLHE) LDTP12679 17.15  LDD2041 
UDP-N-acetylglucosamine transferase subunit ALG14 homolog (ALG14) LDTP10293 10.48  LDD2041 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 11.63  LDD2041 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 8.82  LDD2041 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 11.88  LDD2041 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 14.32  LDD2041 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 9.51  LDD2041 
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⏷ Show the Full List of 117 Enzyme
74 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 16.91  LDD2041 
ATP synthase subunit a (MT-ATP6) LDTP01804 28.44  LDD2041 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 22.01  LDD2041 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 9.45  LDD2041 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 37.79  LDD2041 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 10.13  LDD2041 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 52.35  LDD2041 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 22.78  LDD2041 
Exportin-T (XPOT) LDTP00810 10.06  LDD2041 
Gasdermin-E (GSDME) LDTP00970 9.65  LDD2041 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 9.71  LDD2041 
Intermembrane lipid transfer protein VPS13A (VPS13A) LDTP10769 8.75  LDD2041 
Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) LDTP01100 12.21  LDD2041 
Lysosome membrane protein 2 (SCARB2) LDTP06034 16.45  LDD2041 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 13.83  LDD2041 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 9.19  LDD2041 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 12.13  LDD2041 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 9.32  LDD2041 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 20.68  LDD2041 
Metaxin-1 (MTX1) LDTP05900 26.35  LDD2041 
Metaxin-3 (MTX3) LDTP14970 12.73  LDD2041 
MFS-type transporter SLC18B1 (SLC18B1) LDTP07462 10.41  LDD2041 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 12.04  LDD2041 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 9.71  LDD2041 
Mitochondrial chaperone BCS1 (BCS1L) LDTP13823 10.85  LDD2041 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 19.97  LDD2041 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 10.41  LDD2041 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 60.13  LDD2041 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 88.65  LDD2041 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 9.58  LDD2041 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 11.79  LDD2041 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 13.74  LDD2041 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 10.06  LDD2041 
Mpv17-like protein 2 (MPV17L2) LDTP14952 11.63  LDD2041 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 12.73  LDD2041 
Nucleoporin NDC1 (NDC1) LDTP11213 14.93  LDD2041 
Prosaposin (PSAP) LDTP02215 12.82  LDD2041 
Protein ARV1 (ARV1) LDTP11812 17.03  LDD2041 
Protein FAM8A1 (FAM8A1) LDTP16190 18.25  LDD2041 
Protein GPR107 (GPR107) LDTP07236 8.82  LDD2041 
Protein GPR108 (GPR108) LDTP12383 16.22  LDD2041 
Protein spinster homolog 1 (SPNS1) LDTP11844 16.22  LDD2041 
Protein tweety homolog 3 (TTYH3) LDTP11615 9.85  LDD2041 
Protein wntless homolog (WLS) LDTP07156 9.06  LDD2041 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 14.42  LDD2041 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 13.00  LDD2041 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 13.09  LDD2041 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 25.46  LDD2041 
Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15) LDTP11826 10.85  LDD2041 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 13.83  LDD2041 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 15.56  LDD2041 
Stomatin (STOM) LDTP03380 8.82  LDD2041 
Surfeit locus protein 4 (SURF4) LDTP00592 21.11  LDD2041 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 12.91  LDD2041 
Tetraspanin-10 (TSPAN10) LDTP15967 12.55  LDD2041 
Tetraspanin-3 (TSPAN3) LDTP16813 18.64  LDD2041 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 8.88  LDD2041 
Translocator protein (TSPO) LDTP03546 23.26  LDD2041 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 37.27  LDD2041 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 15.35  LDD2041 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 15.89  LDD2041 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 11.00  LDD2041 
Transmembrane protein 126A (TMEM126A) LDTP15948 29.65  LDD2041 
Transmembrane protein 160 (TMEM160) LDTP20002 33.82  LDD2041 
Transmembrane protein 199 (TMEM199) LDTP08881 23.26  LDD2041 
Transmembrane protein 205 (TMEM205) LDTP07667 10.20  LDD2041 
Transmembrane protein 230 (TMEM230) LDTP10065 13.00  LDD2041 
Transmembrane protein 87A (TMEM87A) LDTP15481 13.93  LDD2041 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 18.90  LDD2041 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 50.91  LDD2041 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 36.50  LDD2041 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 10.70  LDD2041 
Zinc transporter 7 (SLC30A7) LDTP09180 11.63  LDD2041 
Zinc transporter SLC39A7 (SLC39A7) LDTP09769 12.73  LDD2041 
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⏷ Show the Full List of 74 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Forkhead-associated domain-containing protein 1 (FHAD1) LDTP16717 34.30  LDD2041 
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92 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 15.67  LDD2041 
Apolipoprotein L2 (APOL2) LDTP11076 99.73  LDD2041 
Armadillo repeat-containing protein 10 (ARMC10) LDTP08793 10.63  LDD2041 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 9.06  LDD2041 
c-Myc-binding protein (MYCBP) LDTP10857 16.80  LDD2041 
Calumenin (CALU) LDTP00887 10.41  LDD2041 
Clustered mitochondria protein homolog (CLUH) LDTP14486 12.13  LDD2041 
Cold-inducible RNA-binding protein (CIRBP) LDTP06022 10.34  LDD2041 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 29.04  LDD2041 
Dynactin subunit 3 (DCTN3) LDTP01359 11.71  LDD2041 
Dystonin (DST) LDTP05386 34.78  LDD2041 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 15.78  LDD2041 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 9.06  LDD2041 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 11.47  LDD2041 
Ganglioside GM2 activator (GM2A) LDTP02927 14.22  LDD2041 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 14.12  LDD2041 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 8.57  LDD2041 
HCLS1-associated protein X-1 (HAX1) LDTP00199 9.99  LDD2041 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 8.88  LDD2041 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 9.99  LDD2041 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 9.38  LDD2041 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 8.75  LDD2041 
Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) LDTP04714 11.63  LDD2041 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 9.99  LDD2041 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 8.57  LDD2041 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 11.71  LDD2041 
Kinetochore protein Spc24 (SPC24) LDTP09069 9.32  LDD2041 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 9.38  LDD2041 
Large proline-rich protein BAG6 (BAG6) LDTP04094 10.41  LDD2041 
Large ribosomal subunit protein mL64 (GADD45GIP1) LDTP09297 10.41  LDD2041 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 10.06  LDD2041 
m-AAA protease-interacting protein 1, mitochondrial (MAIP1) LDTP09644 9.51  LDD2041 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 30.06  LDD2041 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 9.78  LDD2041 
Mitochondrial dynamics protein MIEF1 (MIEF1) LDTP12418 9.92  LDD2041 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 34.78  LDD2041 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 9.13  LDD2041 
Mitochondrial import receptor subunit TOM20 homolog (TOMM20) LDTP06373 27.10  LDD2041 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 84.45  LDD2041 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 35.02  LDD2041 
Negative elongation factor C/D (NELFCD) LDTP08594 16.34  LDD2041 
Neuferricin (CYB5D2) LDTP15623 11.24  LDD2041 
NLR family member X1 (NLRX1) LDTP08248 16.80  LDD2041 
Nucleobindin-2 (NUCB2) LDTP05160 18.77  LDD2041 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 17.27  LDD2041 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 21.86  LDD2041 
Nurim (NRM) LDTP08606 12.55  LDD2041 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 9.19  LDD2041 
Optic atrophy 3 protein (OPA3) LDTP16006 24.59  LDD2041 
p53 and DNA damage-regulated protein 1 (PDRG1) LDTP16099 23.26  LDD2041 
Protein CEBPZOS (CEBPZOS) LDTP18883 18.51  LDD2041 
Protein FAM114A2 (FAM114A2) LDTP16080 19.97  LDD2041 
Protein FAM118B (FAM118B) LDTP15852 9.06  LDD2041 
Protein FAM162A (FAM162A) LDTP10056 11.24  LDD2041 
Protein FAM177A1 (FAM177A1) LDTP15398 9.13  LDD2041 
Protein FAM3C (FAM3C) LDTP09773 8.82  LDD2041 
Protein jagunal homolog 1 (JAGN1) LDTP08904 9.32  LDD2041 
Protein LYRIC (MTDH) LDTP08224 15.14  LDD2041 
Protein PRRC1 (PRRC1) LDTP15778 9.45  LDD2041 
Protein unc-119 homolog A (UNC119) LDTP05868 42.52  LDD2041 
Protein unc-119 homolog B (UNC119B) LDTP00105 28.64  LDD2041 
Protein YIF1A (YIF1A) LDTP01494 9.85  LDD2041 
Reticulocalbin-2 (RCN2) LDTP06097 18.25  LDD2041 
Reticulon-2 (RTN2) LDTP01167 11.96  LDD2041 
Reticulon-3 (RTN3) LDTP01522 21.11  LDD2041 
Reticulon-4 (RTN4) LDTP12412 30.91  LDD2041 
S1 RNA-binding domain-containing protein 1 (SRBD1) LDTP17715 8.63  LDD2041 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 18.77  LDD2041 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 11.24  LDD2041 
Synaptogyrin-2 (SYNGR2) LDTP00859 9.71  LDD2041 
Syntaxin-18 (STX18) LDTP13086 20.82  LDD2041 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 8.75  LDD2041 
Tetraspanin-6 (TSPAN6) LDTP14458 28.25  LDD2041 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 8.82  LDD2041 
Tetratricopeptide repeat protein 21B (TTC21B) LDTP08073 11.79  LDD2041 
Tetratricopeptide repeat protein 38 (TTC38) LDTP19372 11.24  LDD2041 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 17.39  LDD2041 
TraB domain-containing protein (TRABD) LDTP19963 12.82  LDD2041 
Transducin beta-like protein 2 (TBL2) LDTP16285 9.00  LDD2041 
Transformer-2 protein homolog beta (TRA2B) LDTP05036 8.75  LDD2041 
Transmembrane emp24 domain-containing protein 5 (TMED5) LDTP13967 9.78  LDD2041 
Transmembrane protein 209 (TMEM209) LDTP18272 16.68  LDD2041 
Tubulin beta chain (TUBB) LDTP02205 21.11  LDD2041 
Tubulin beta-2A chain (TUBB2A) LDTP05998 22.32  LDD2041 
Tubulin beta-2B chain (TUBB2B) LDTP11277 28.44  LDD2041 
Tubulin beta-4A chain (TUBB4A) LDTP02037 21.86  LDD2041 
Tubulin beta-4B chain (TUBB4B) LDTP05076 22.16  LDD2041 
Tubulin beta-6 chain (TUBB6) LDTP11233 14.72  LDD2041 
Tudor and KH domain-containing protein (TDRKH) LDTP13922 9.51  LDD2041 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 35.02  LDD2041 
Vimentin (VIM) LDTP02297 12.04  LDD2041 
Zinc finger CCHC domain-containing protein 3 (ZCCHC3) LDTP12623 11.08  LDD2041 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587