Details of the Probe

General Information of Probe

Probe ID
LDPC0385
Probe Name
C143
Synonyms
Z4225951768
Probe Type
PAL-AfBPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 327.8
Lipid-water partition coefficient (xlogp) 3.2
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C18H18ClN3O
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-5-chloro-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxamide
Canonical SMILES
C#CCCC1(N=N1)CCNC(=O)C2C3C2C4=C(C3)C(=CC=C4)Cl
InChI
InChI=1S/C18H18ClN3O/c1-2-3-7-18(21-22-18)8-9-20-17(23)16-13-10-12-11(15(13)16)5-4-6-14(12)19/h1,4-6,13,15-16H,3,7-10H2,(H,20,23)
InChIKey
CEESQXLETZBRLG-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

131 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 14.22  LDD1825 
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (BCKDHA) LDTP02627 14.42  LDD1825 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 13.64  LDD1825 
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) LDTP02000 14.93  LDD1825 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 13.74  LDD1825 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 13.55  LDD1825 
Acid ceramidase (ASAH1) LDTP05905 26.91  LDD1825 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 14.22  LDD1825 
ADP-dependent glucokinase (ADPGK) LDTP11127 25.99  LDD1825 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 27.47  LDD1825 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 12.73  LDD1825 
Antigen peptide transporter 1 (TAP1) LDTP05408 13.45  LDD1825 
Atlastin-2 (ATL2) LDTP09251 17.88  LDD1825 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 15.56  LDD1825 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 14.62  LDD1825 
Beta-galactosidase (GLB1) LDTP02837 14.12  LDD1825 
Bifunctional coenzyme A synthase (COASY) LDTP05736 57.68  LDD1825 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 14.72  LDD1825 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 23.10  LDD1825 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 36.00  LDD1825 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 13.74  LDD1825 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 62.25  LDD1825 
Catechol O-methyltransferase (COMT) LDTP03145 16.00  LDD1825 
CCR4-NOT transcription complex subunit 4 (CNOT4) LDTP01640 30.70  LDD1825 
Ceramide glucosyltransferase (UGCG) LDTP06617 29.86  LDD1825 
Ceramide synthase 2 (CERS2) LDTP10329 24.93  LDD1825 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 14.83  LDD1825 
COP9 signalosome complex subunit 3 (COPS3) LDTP13675 12.38  LDD1825 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 15.67  LDD1825 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 99.73  LDD1825 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 56.49  LDD1825 
Cytochrome b5 type B (CYB5B) LDTP00697 73.01  LDD1825 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 12.38  LDD1825 
Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7A2L) LDTP14427 13.27  LDD1825 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 45.89  LDD1825 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 47.18  LDD1825 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 33.13  LDD1825 
Delta(14)-sterol reductase TM7SF2 (TM7SF2) LDTP01389 18.64  LDD1825 
Delta(24)-sterol reductase (DHCR24) LDTP06375 16.34  LDD1825 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 18.00  LDD1825 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 15.56  LDD1825 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 13.74  LDD1825 
Dihydroxyacetone phosphate acyltransferase (GNPAT) LDTP00577 12.47  LDD1825 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 20.39  LDD1825 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 22.47  LDD1825 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 18.51  LDD1825 
E3 ubiquitin-protein ligase AMFR (AMFR) LDTP13491 14.32  LDD1825 
EH domain-containing protein 4 (EHD4) LDTP11788 13.93  LDD1825 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 21.11  LDD1825 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 15.56  LDD1825 
Endoplasmic reticulum metallopeptidase 1 (ERMP1) LDTP08017 37.01  LDD1825 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 13.93  LDD1825 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 23.26  LDD1825 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 17.51  LDD1825 
Epoxide hydrolase 1 (EPHX1) LDTP02175 15.78  LDD1825 
Exosome complex component RRP42 (EXOSC7) LDTP06283 17.03  LDD1825 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 19.70  LDD1825 
Farnesyl pyrophosphate synthase (FDPS) LDTP02721 14.22  LDD1825 
Ferrochelatase, mitochondrial (FECH) LDTP03198 15.35  LDD1825 
Fumarylacetoacetase (FAH) LDTP02868 12.91  LDD1825 
Geranylgeranyl transferase type-2 subunit beta (RABGGTB) LDTP04569 12.91  LDD1825 
Heme A synthase COX15 (COX15) LDTP07931 13.18  LDD1825 
Heme oxygenase 1 (HMOX1) LDTP02359 40.79  LDD1825 
Heme oxygenase 2 (HMOX2) LDTP03540 27.10  LDD1825 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 14.12  LDD1825 
Hexokinase-2 (HK2) LDTP04531 17.15  LDD1825 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 54.95  LDD1825 
Isochorismatase domain-containing protein 1 (ISOC1) LDTP19851 19.29  LDD1825 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 20.53  LDD1825 
Lanosterol synthase (LSS) LDTP04183 16.91  LDD1825 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 16.22  LDD1825 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 77.17  LDD1825 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 76.11  LDD1825 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 20.11  LDD1825 
Lysophosphatidylserine lipase ABHD12 (ABHD12) LDTP08799 14.52  LDD1825 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 28.05  LDD1825 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 18.00  LDD1825 
Lysosomal protective protein (CTSA) LDTP02505 19.97  LDD1825 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 14.03  LDD1825 
Mannose-1-phosphate guanyltransferase beta (GMPPB) LDTP14141 12.82  LDD1825 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 39.40  LDD1825 
Microsomal glutathione S-transferase 2 (MGST2) LDTP10966 12.73  LDD1825 
Minor histocompatibility antigen H13 (HM13) LDTP09396 33.13  LDD1825 
Mitochondrial Rho GTPase 2 (RHOT2) LDTP08596 14.93  LDD1825 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 13.45  LDD1825 
N-lysine methyltransferase SMYD2 (SMYD2) LDTP12509 26.72  LDD1825 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 29.65  LDD1825 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 23.43  LDD1825 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 26.72  LDD1825 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 99.73  LDD1825 
NADH-ubiquinone oxidoreductase chain 2 (MT-ND2) LDTP01983 46.53  LDD1825 
NADPH--cytochrome P450 reductase (POR) LDTP02848 19.03  LDD1825 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 30.06  LDD1825 
Pachytene checkpoint protein 2 homolog (TRIP13) LDTP06432 20.82  LDD1825 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 54.95  LDD1825 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 14.03  LDD1825 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 17.27  LDD1825 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 51.27  LDD1825 
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (PAOX) LDTP07620 19.16  LDD1825 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 13.93  LDD1825 
Phosphatidylserine synthase 1 (PTDSS1) LDTP04203 26.17  LDD1825 
Polyamine-transporting ATPase 13A2 (ATP13A2) LDTP12386 16.56  LDD1825 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 18.00  LDD1825 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 21.86  LDD1825 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 14.32  LDD1825 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 17.03  LDD1825 
Prostaglandin reductase 3 (PTGR3) LDTP15422 32.22  LDD1825 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 25.46  LDD1825 
Protein O-GlcNAcase (OGA) LDTP00988 13.09  LDD1825 
Protein SCO2 homolog, mitochondrial (SCO2) LDTP00877 13.74  LDD1825 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 19.70  LDD1825 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 20.53  LDD1825 
Ras-related protein Rab-24 (RAB24) LDTP10020 15.89  LDD1825 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 18.77  LDD1825 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 14.03  LDD1825 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 24.08  LDD1825 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 17.88  LDD1825 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 13.27  LDD1825 
Serine/threonine-protein phosphatase 4 regulatory subunit 3A (PPP4R3A) LDTP07417 15.24  LDD1825 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 20.68  LDD1825 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 13.18  LDD1825 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 17.51  LDD1825 
Sphingosine kinase 2 (SPHK2) LDTP12490 13.64  LDD1825 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 22.01  LDD1825 
TLC domain-containing protein 1 (TLCD1) LDTP10182 99.73  LDD1825 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 18.25  LDD1825 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 18.00  LDD1825 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 19.84  LDD1825 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 28.25  LDD1825 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 32.45  LDD1825 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 19.84  LDD1825 
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⏷ Show the Full List of 131 Enzyme
100 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 25.28  LDD1825 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 33.36  LDD1825 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 14.72  LDD1825 
ADP/ATP translocase 2 (SLC25A5) LDTP02087 13.45  LDD1825 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 16.91  LDD1825 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 49.18  LDD1825 
ATP synthase subunit e, mitochondrial (ATP5ME) LDTP14717 13.00  LDD1825 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 58.89  LDD1825 
B-cell receptor-associated protein 31 (BCAP31) LDTP04426 13.18  LDD1825 
BRI3-binding protein (BRI3BP) LDTP15648 34.06  LDD1825 
Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) LDTP08469 26.17  LDD1825 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 25.28  LDD1825 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 58.49  LDD1825 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 13.09  LDD1825 
Derlin-1 (DERL1) LDTP11245 16.56  LDD1825 
Derlin-2 (DERL2) LDTP11634 14.03  LDD1825 
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 13.00  LDD1825 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 43.71  LDD1825 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 20.39  LDD1825 
Gasdermin-E (GSDME) LDTP00970 19.70  LDD1825 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 21.71  LDD1825 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 14.32  LDD1825 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 12.82  LDD1825 
H(+)/Cl(-) exchange transporter 6 (CLCN6) LDTP04462 18.64  LDD1825 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 25.11  LDD1825 
Importin-4 (IPO4) LDTP09515 18.77  LDD1825 
Integral membrane protein 2B (ITM2B) LDTP13833 16.11  LDD1825 
Integral membrane protein 2C (ITM2C) LDTP12451 20.11  LDD1825 
Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) LDTP01100 12.55  LDD1825 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 13.93  LDD1825 
Lysosomal cobalamin transport escort protein LMBD1 (LMBRD1) LDTP12636 64.45  LDD1825 
Lysosome membrane protein 2 (SCARB2) LDTP06034 32.90  LDD1825 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 14.62  LDD1825 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 13.93  LDD1825 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 33.36  LDD1825 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 22.16  LDD1825 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 19.84  LDD1825 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 20.11  LDD1825 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 56.49  LDD1825 
Metal cation symporter ZIP14 (SLC39A14) LDTP06293 12.38  LDD1825 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 13.64  LDD1825 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 13.27  LDD1825 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 15.35  LDD1825 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 14.72  LDD1825 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 39.95  LDD1825 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 30.06  LDD1825 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 99.73  LDD1825 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 43.41  LDD1825 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 19.97  LDD1825 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 31.78  LDD1825 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 14.72  LDD1825 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 35.02  LDD1825 
Mpv17-like protein 2 (MPV17L2) LDTP14952 30.48  LDD1825 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 14.12  LDD1825 
Nucleoporin NDC1 (NDC1) LDTP11213 19.16  LDD1825 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 18.00  LDD1825 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 65.34  LDD1825 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 27.28  LDD1825 
Prosaposin (PSAP) LDTP02215 48.50  LDD1825 
Protein ARV1 (ARV1) LDTP11812 19.97  LDD1825 
Protein ERGIC-53 (LMAN1) LDTP04237 13.93  LDD1825 
Protein GPR107 (GPR107) LDTP07236 25.11  LDD1825 
Protein Mpv17 (MPV17) LDTP03869 12.64  LDD1825 
Protein spinster homolog 1 (SPNS1) LDTP11844 16.00  LDD1825 
Protein tweety homolog 3 (TTYH3) LDTP11615 44.63  LDD1825 
Protein wntless homolog (WLS) LDTP07156 19.56  LDD1825 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 25.81  LDD1825 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 24.42  LDD1825 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 21.41  LDD1825 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 26.72  LDD1825 
Sideroflexin-4 (SFXN4) LDTP07531 27.47  LDD1825 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 27.28  LDD1825 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 70.52  LDD1825 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 30.91  LDD1825 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 47.18  LDD1825 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 16.34  LDD1825 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 12.21  LDD1825 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 24.42  LDD1825 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 68.12  LDD1825 
Stomatin (STOM) LDTP03380 17.88  LDD1825 
SUN domain-containing protein 1 (SUN1) LDTP01454 13.18  LDD1825 
Surfeit locus protein 4 (SURF4) LDTP00592 15.56  LDD1825 
Tetraspanin-3 (TSPAN3) LDTP16813 74.54  LDD1825 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 34.78  LDD1825 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 66.72  LDD1825 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 25.99  LDD1825 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 12.30  LDD1825 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 21.56  LDD1825 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 12.73  LDD1825 
Transmembrane protein 126A (TMEM126A) LDTP15948 67.18  LDD1825 
Transmembrane protein 160 (TMEM160) LDTP20002 34.78  LDD1825 
Transmembrane protein 199 (TMEM199) LDTP08881 46.85  LDD1825 
Transmembrane protein 230 (TMEM230) LDTP10065 23.10  LDD1825 
Transmembrane protein 33 (TMEM33) LDTP04787 12.82  LDD1825 
Transmembrane protein 59 (TMEM59) LDTP11406 12.91  LDD1825 
Transmembrane protein 87A (TMEM87A) LDTP15481 43.71  LDD1825 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 29.04  LDD1825 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 54.95  LDD1825 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 63.56  LDD1825 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 22.16  LDD1825 
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⏷ Show the Full List of 100 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 21.26  LDD1825 
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1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 18.13  LDD1825 
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86 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 12.55  LDD1825 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 24.93  LDD1825 
Annexin A7 (ANXA7) LDTP03030 13.64  LDD1825 
Apolipoprotein L2 (APOL2) LDTP11076 99.73  LDD1825 
Ataxin-10 (ATXN10) LDTP13091 14.12  LDD1825 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 16.34  LDD1825 
Centrin-2 (CETN2) LDTP03926 19.16  LDD1825 
Centromere protein K (CENPK) LDTP11143 44.02  LDD1825 
Clustered mitochondria protein homolog (CLUH) LDTP14486 18.25  LDD1825 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 15.14  LDD1825 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 59.30  LDD1825 
Dynactin subunit 3 (DCTN3) LDTP01359 18.90  LDD1825 
Dynactin subunit 4 (DCTN4) LDTP13402 15.14  LDD1825 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 15.89  LDD1825 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 37.27  LDD1825 
Engulfment and cell motility protein 2 (ELMO2) LDTP10469 14.52  LDD1825 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 64.45  LDD1825 
Galanin peptides (GAL) LDTP03175 16.45  LDD1825 
Ganglioside GM2 activator (GM2A) LDTP02927 14.93  LDD1825 
General transcription factor IIF subunit 1 (GTF2F1) LDTP03729 41.93  LDD1825 
Golgi apparatus protein 1 (GLG1) LDTP09920 15.03  LDD1825 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 34.06  LDD1825 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 18.90  LDD1825 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 28.84  LDD1825 
HIG1 domain family member 1A, mitochondrial (HIGD1A) LDTP13797 31.78  LDD1825 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 22.94  LDD1825 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 15.89  LDD1825 
Large proline-rich protein BAG6 (BAG6) LDTP04094 15.67  LDD1825 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 21.11  LDD1825 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 23.43  LDD1825 
Mediator of RNA polymerase II transcription subunit 4 (MED4) LDTP12377 16.56  LDD1825 
Membralin (TMEM259) LDTP14939 30.48  LDD1825 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 14.03  LDD1825 
MICOS complex subunit MIC27 (APOOL) LDTP07718 12.38  LDD1825 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 24.93  LDD1825 
Mitochondrial fission 1 protein (FIS1) LDTP13982 13.36  LDD1825 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 29.24  LDD1825 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 59.30  LDD1825 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 55.72  LDD1825 
Nucleobindin-1 (NUCB1) LDTP05375 28.05  LDD1825 
Nucleobindin-2 (NUCB2) LDTP05160 58.08  LDD1825 
Nucleolar protein 9 (NOP9) LDTP15283 18.51  LDD1825 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 14.22  LDD1825 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 24.08  LDD1825 
Optic atrophy 3 protein (OPA3) LDTP16006 32.45  LDD1825 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 45.89  LDD1825 
Polyadenylate-binding protein-interacting protein 1 (PAIP1) LDTP11682 12.73  LDD1825 
Programmed cell death protein 5 (PDCD5) LDTP00417 23.92  LDD1825 
Prohibitin-2 (PHB2) LDTP10924 12.21  LDD1825 
Protein CEBPZOS (CEBPZOS) LDTP18883 44.02  LDD1825 
Protein FAM114A2 (FAM114A2) LDTP16080 41.07  LDD1825 
Protein FAM162A (FAM162A) LDTP10056 46.85  LDD1825 
Protein FAM177A1 (FAM177A1) LDTP15398 15.78  LDD1825 
Protein FAM3C (FAM3C) LDTP09773 13.27  LDD1825 
Protein LYRIC (MTDH) LDTP08224 16.00  LDD1825 
Protein SET (SET) LDTP05277 13.09  LDD1825 
Protein unc-119 homolog B (UNC119B) LDTP00105 47.50  LDD1825 
Protein YIF1A (YIF1A) LDTP01494 15.03  LDD1825 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 13.09  LDD1825 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 14.22  LDD1825 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 14.12  LDD1825 
Reticulocalbin-2 (RCN2) LDTP06097 13.27  LDD1825 
Reticulon-3 (RTN3) LDTP01522 68.12  LDD1825 
Reticulon-4 (RTN4) LDTP12412 32.67  LDD1825 
RNA-binding protein 3 (RBM3) LDTP05226 12.82  LDD1825 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 25.63  LDD1825 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 15.35  LDD1825 
Small integral membrane protein 19 (SMIM19) LDTP18145 78.79  LDD1825 
Synaptic vesicle glycoprotein 2A (SV2A) LDTP07934 14.32  LDD1825 
Synaptogyrin-2 (SYNGR2) LDTP00859 31.34  LDD1825 
Syntaxin-10 (STX10) LDTP00986 26.91  LDD1825 
Syntaxin-18 (STX18) LDTP13086 31.56  LDD1825 
Tetraspanin-6 (TSPAN6) LDTP14458 47.84  LDD1825 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 12.30  LDD1825 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 27.47  LDD1825 
TraB domain-containing protein (TRABD) LDTP19963 21.71  LDD1825 
Trans-Golgi network integral membrane protein 2 (TGOLN2) LDTP00779 25.11  LDD1825 
Transducin beta-like protein 2 (TBL2) LDTP16285 18.38  LDD1825 
Transmembrane protein 209 (TMEM209) LDTP18272 15.67  LDD1825 
Transmembrane protein 35B (TMEM35B) LDTP19785 22.01  LDD1825 
Trophoblast glycoprotein (TPBG) LDTP05960 17.63  LDD1825 
Tumor protein D52 (TPD52) LDTP04703 14.72  LDD1825 
Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) LDTP15634 51.63  LDD1825 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 26.91  LDD1825 
Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) LDTP01163 22.63  LDD1825 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 28.05  LDD1825 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1825 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587