Details of the Probe

General Information of Probe

Probe ID
LDPC0372
Probe Name
C130
Synonyms
Z4282859929
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 353.4
Lipid-water partition coefficient (xlogp) 2.7
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C20H23N3O3
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-[cyclopropyl(2,3-dihydro-1,4-benzodioxin-6-yl)methyl]propanamide
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)NC(C2CC2)C3=CC4=C(C=C3)OCCO4
InChI
InChI=1S/C20H23N3O3/c1-2-3-9-20(22-23-20)10-8-18(24)21-19(14-4-5-14)15-6-7-16-17(13-15)26-12-11-25-16/h1,6-7,13-14,19H,3-5,8-12H2,(H,21,24)
InChIKey
IQMZOGRWKTYUOI-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

178 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 11.24  LDD1812 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 11.24  LDD1812 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 11.39  LDD1812 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 11.39  LDD1812 
5'-nucleotidase domain-containing protein 1 (NT5DC1) LDTP17247 7.11  LDD1812 
5'-nucleotidase domain-containing protein 1 (NT5DC1) LDTP17247 7.11  LDD1812 
Acid ceramidase (ASAH1) LDTP05905 8.75  LDD1812 
Acid ceramidase (ASAH1) LDTP05905 8.75  LDD1812 
ADP-dependent glucokinase (ADPGK) LDTP11127 8.11  LDD1812 
ADP-dependent glucokinase (ADPGK) LDTP11127 8.11  LDD1812 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 8.88  LDD1812 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 8.88  LDD1812 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 7.01  LDD1812 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 7.01  LDD1812 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 15.35  LDD1812 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 15.35  LDD1812 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 7.94  LDD1812 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 7.94  LDD1812 
Beta-galactosidase (GLB1) LDTP02837 11.16  LDD1812 
Beta-galactosidase (GLB1) LDTP02837 11.16  LDD1812 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 6.87  LDD1812 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 6.87  LDD1812 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 12.38  LDD1812 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 12.38  LDD1812 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 8.22  LDD1812 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 8.22  LDD1812 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 20.68  LDD1812 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 20.68  LDD1812 
Ceramide synthase 2 (CERS2) LDTP10329 15.03  LDD1812 
Ceramide synthase 2 (CERS2) LDTP10329 15.03  LDD1812 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 17.63  LDD1812 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 17.63  LDD1812 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 16.91  LDD1812 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 16.91  LDD1812 
Cytochrome b5 type B (CYB5B) LDTP00697 20.25  LDD1812 
Cytochrome b5 type B (CYB5B) LDTP00697 20.25  LDD1812 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 8.00  LDD1812 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 8.00  LDD1812 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 7.26  LDD1812 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 7.26  LDD1812 
Delta(24)-sterol reductase (DHCR24) LDTP06375 11.88  LDD1812 
Delta(24)-sterol reductase (DHCR24) LDTP06375 11.88  LDD1812 
Dihydrofolate reductase (DHFR) LDTP01769 15.24  LDD1812 
Dihydrofolate reductase (DHFR) LDTP01769 15.24  LDD1812 
DNA replication licensing factor MCM2 (MCM2) LDTP04286 8.63  LDD1812 
DNA replication licensing factor MCM2 (MCM2) LDTP04286 8.63  LDD1812 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 8.28  LDD1812 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 8.28  LDD1812 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 8.17  LDD1812 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 8.17  LDD1812 
E3 ubiquitin-protein ligase RNF14 (RNF14) LDTP13154 8.82  LDD1812 
E3 ubiquitin-protein ligase RNF14 (RNF14) LDTP13154 8.82  LDD1812 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 6.28  LDD1812 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 6.28  LDD1812 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 23.26  LDD1812 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 23.26  LDD1812 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 8.82  LDD1812 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 8.82  LDD1812 
Epoxide hydrolase 1 (EPHX1) LDTP02175 18.90  LDD1812 
Epoxide hydrolase 1 (EPHX1) LDTP02175 18.90  LDD1812 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 8.82  LDD1812 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 8.82  LDD1812 
Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) LDTP17305 9.19  LDD1812 
Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) LDTP17305 9.19  LDD1812 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 7.57  LDD1812 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 7.57  LDD1812 
Heme oxygenase 1 (HMOX1) LDTP02359 30.06  LDD1812 
Heme oxygenase 1 (HMOX1) LDTP02359 30.06  LDD1812 
Heme oxygenase 2 (HMOX2) LDTP03540 45.89  LDD1812 
Heme oxygenase 2 (HMOX2) LDTP03540 45.89  LDD1812 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 6.36  LDD1812 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 6.36  LDD1812 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 7.89  LDD1812 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 7.89  LDD1812 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 12.38  LDD1812 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 12.38  LDD1812 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 7.41  LDD1812 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 7.41  LDD1812 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 14.62  LDD1812 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 14.62  LDD1812 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 6.41  LDD1812 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 6.41  LDD1812 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 17.15  LDD1812 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 17.15  LDD1812 
Lysosomal alpha-glucosidase (GAA) LDTP02486 8.11  LDD1812 
Lysosomal alpha-glucosidase (GAA) LDTP02486 8.11  LDD1812 
Lysosomal alpha-mannosidase (MAN2B1) LDTP00338 6.50  LDD1812 
Lysosomal alpha-mannosidase (MAN2B1) LDTP00338 6.50  LDD1812 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 13.45  LDD1812 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 13.45  LDD1812 
Lysosomal protective protein (CTSA) LDTP02505 19.16  LDD1812 
Lysosomal protective protein (CTSA) LDTP02505 19.16  LDD1812 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 16.11  LDD1812 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 16.11  LDD1812 
Minor histocompatibility antigen H13 (HM13) LDTP09396 6.59  LDD1812 
Minor histocompatibility antigen H13 (HM13) LDTP09396 6.59  LDD1812 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 8.46  LDD1812 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 8.46  LDD1812 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 7.31  LDD1812 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 7.31  LDD1812 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 8.34  LDD1812 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 8.34  LDD1812 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 7.26  LDD1812 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 7.26  LDD1812 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 6.63  LDD1812 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 6.63  LDD1812 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 9.65  LDD1812 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 9.65  LDD1812 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 13.45  LDD1812 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 13.45  LDD1812 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 6.68  LDD1812 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 6.68  LDD1812 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 17.15  LDD1812 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 17.15  LDD1812 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 7.94  LDD1812 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 7.94  LDD1812 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 16.00  LDD1812 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 16.00  LDD1812 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 7.52  LDD1812 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 7.52  LDD1812 
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (PAOX) LDTP07620 12.38  LDD1812 
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (PAOX) LDTP07620 12.38  LDD1812 
Phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3) LDTP09155 6.68  LDD1812 
Phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3) LDTP09155 6.68  LDD1812 
Phospholipase A2 group XV (PLA2G15) LDTP09088 7.67  LDD1812 
Phospholipase A2 group XV (PLA2G15) LDTP09088 7.67  LDD1812 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 12.04  LDD1812 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 12.04  LDD1812 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 18.38  LDD1812 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 18.38  LDD1812 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 8.57  LDD1812 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 8.57  LDD1812 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 10.27  LDD1812 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 10.27  LDD1812 
Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) LDTP02679 7.41  LDD1812 
Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) LDTP02679 7.41  LDD1812 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 9.38  LDD1812 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 9.38  LDD1812 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 8.28  LDD1812 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 8.28  LDD1812 
Protein O-GlcNAcase (OGA) LDTP00988 8.57  LDD1812 
Protein O-GlcNAcase (OGA) LDTP00988 8.57  LDD1812 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 10.93  LDD1812 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 10.93  LDD1812 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 6.63  LDD1812 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 6.63  LDD1812 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 18.25  LDD1812 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 18.25  LDD1812 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 19.70  LDD1812 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 19.70  LDD1812 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 15.03  LDD1812 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 15.03  LDD1812 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 14.62  LDD1812 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 14.62  LDD1812 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 17.51  LDD1812 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 17.51  LDD1812 
Sialate O-acetylesterase (SIAE) LDTP12135 45.25  LDD1812 
Sialate O-acetylesterase (SIAE) LDTP12135 45.25  LDD1812 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 7.62  LDD1812 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 7.62  LDD1812 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 6.87  LDD1812 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 6.87  LDD1812 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 9.99  LDD1812 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 9.99  LDD1812 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 6.87  LDD1812 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 6.87  LDD1812 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 8.69  LDD1812 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 8.69  LDD1812 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 10.70  LDD1812 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 10.70  LDD1812 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 6.32  LDD1812 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 6.32  LDD1812 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 9.45  LDD1812 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 9.45  LDD1812 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 7.67  LDD1812 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 7.67  LDD1812 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 7.41  LDD1812 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 7.41  LDD1812 
------------------------------------------------------------------------------------
⏷ Show the Full List of 178 Enzyme
104 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 10.85  LDD1812 
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 10.85  LDD1812 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 9.78  LDD1812 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 9.78  LDD1812 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 16.80  LDD1812 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 16.80  LDD1812 
BRI3-binding protein (BRI3BP) LDTP15648 8.63  LDD1812 
BRI3-binding protein (BRI3BP) LDTP15648 8.63  LDD1812 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 19.03  LDD1812 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 19.03  LDD1812 
Derlin-1 (DERL1) LDTP11245 7.06  LDD1812 
Derlin-1 (DERL1) LDTP11245 7.06  LDD1812 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 25.99  LDD1812 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 25.99  LDD1812 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 7.01  LDD1812 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 7.01  LDD1812 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 6.45  LDD1812 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 6.45  LDD1812 
Lysosome membrane protein 2 (SCARB2) LDTP06034 25.99  LDD1812 
Lysosome membrane protein 2 (SCARB2) LDTP06034 25.99  LDD1812 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 12.55  LDD1812 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 12.55  LDD1812 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 10.20  LDD1812 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 10.20  LDD1812 
Metaxin-1 (MTX1) LDTP05900 10.20  LDD1812 
Metaxin-1 (MTX1) LDTP05900 10.20  LDD1812 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 8.28  LDD1812 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 8.28  LDD1812 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 7.89  LDD1812 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 7.89  LDD1812 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 8.46  LDD1812 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 8.46  LDD1812 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 9.06  LDD1812 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 9.06  LDD1812 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 37.27  LDD1812 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 37.27  LDD1812 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 53.82  LDD1812 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 53.82  LDD1812 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 15.45  LDD1812 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 15.45  LDD1812 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 6.50  LDD1812 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 6.50  LDD1812 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 6.54  LDD1812 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 6.54  LDD1812 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 11.96  LDD1812 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 11.96  LDD1812 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 9.78  LDD1812 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 9.78  LDD1812 
Nucleoporin NDC1 (NDC1) LDTP11213 8.57  LDD1812 
Nucleoporin NDC1 (NDC1) LDTP11213 8.57  LDD1812 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 8.17  LDD1812 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 8.17  LDD1812 
Prosaposin (PSAP) LDTP02215 20.82  LDD1812 
Prosaposin (PSAP) LDTP02215 20.82  LDD1812 
Protein FAM8A1 (FAM8A1) LDTP16190 8.11  LDD1812 
Protein FAM8A1 (FAM8A1) LDTP16190 8.11  LDD1812 
Protein GPR107 (GPR107) LDTP07236 14.93  LDD1812 
Protein GPR107 (GPR107) LDTP07236 14.93  LDD1812 
Protein tweety homolog 3 (TTYH3) LDTP11615 19.97  LDD1812 
Protein tweety homolog 3 (TTYH3) LDTP11615 19.97  LDD1812 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 8.46  LDD1812 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 8.46  LDD1812 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 17.51  LDD1812 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 17.51  LDD1812 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 9.38  LDD1812 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 9.38  LDD1812 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 16.11  LDD1812 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 16.11  LDD1812 
Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15) LDTP11826 6.96  LDD1812 
Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15) LDTP11826 6.96  LDD1812 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 8.40  LDD1812 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 8.40  LDD1812 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 7.16  LDD1812 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 7.16  LDD1812 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 7.67  LDD1812 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 7.67  LDD1812 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 7.94  LDD1812 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 7.94  LDD1812 
Stomatin (STOM) LDTP03380 7.16  LDD1812 
Stomatin (STOM) LDTP03380 7.16  LDD1812 
Surfeit locus protein 4 (SURF4) LDTP00592 8.06  LDD1812 
Surfeit locus protein 4 (SURF4) LDTP00592 8.06  LDD1812 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 13.55  LDD1812 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 13.55  LDD1812 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 17.39  LDD1812 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 17.39  LDD1812 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 8.34  LDD1812 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 8.34  LDD1812 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 6.41  LDD1812 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 6.41  LDD1812 
Transmembrane protein 126A (TMEM126A) LDTP15948 27.67  LDD1812 
Transmembrane protein 126A (TMEM126A) LDTP15948 27.67  LDD1812 
Transmembrane protein 160 (TMEM160) LDTP20002 13.00  LDD1812 
Transmembrane protein 160 (TMEM160) LDTP20002 13.00  LDD1812 
Transmembrane protein 199 (TMEM199) LDTP08881 23.59  LDD1812 
Transmembrane protein 199 (TMEM199) LDTP08881 23.59  LDD1812 
Transmembrane protein 205 (TMEM205) LDTP07667 6.50  LDD1812 
Transmembrane protein 205 (TMEM205) LDTP07667 6.50  LDD1812 
Vang-like protein 1 (VANGL1) LDTP09288 7.26  LDD1812 
Vang-like protein 1 (VANGL1) LDTP09288 7.26  LDD1812 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 39.40  LDD1812 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 39.40  LDD1812 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 25.99  LDD1812 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 25.99  LDD1812 
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⏷ Show the Full List of 104 Transporter and channel
2 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 6.77  LDD1812 
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 6.77  LDD1812 
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96 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 8.82  LDD1812 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 8.82  LDD1812 
Apolipoprotein L2 (APOL2) LDTP11076 22.63  LDD1812 
Apolipoprotein L2 (APOL2) LDTP11076 22.63  LDD1812 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 8.06  LDD1812 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 8.06  LDD1812 
Calcium-binding and coiled-coil domain-containing protein 2 (CALCOCO2) LDTP05764 7.46  LDD1812 
Calcium-binding and coiled-coil domain-containing protein 2 (CALCOCO2) LDTP05764 7.46  LDD1812 
Centrosomal protein 43 (CEP43) LDTP01652 7.84  LDD1812 
Centrosomal protein 43 (CEP43) LDTP01652 7.84  LDD1812 
Clustered mitochondria protein homolog (CLUH) LDTP14486 12.64  LDD1812 
Clustered mitochondria protein homolog (CLUH) LDTP14486 12.64  LDD1812 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 10.20  LDD1812 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 10.20  LDD1812 
Dynactin subunit 3 (DCTN3) LDTP01359 6.73  LDD1812 
Dynactin subunit 3 (DCTN3) LDTP01359 6.73  LDD1812 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 6.68  LDD1812 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 6.68  LDD1812 
Endoplasmic reticulum resident protein 44 (ERP44) LDTP11144 7.01  LDD1812 
Endoplasmic reticulum resident protein 44 (ERP44) LDTP11144 7.01  LDD1812 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 12.47  LDD1812 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 12.47  LDD1812 
Ganglioside GM2 activator (GM2A) LDTP02927 6.82  LDD1812 
Ganglioside GM2 activator (GM2A) LDTP02927 6.82  LDD1812 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 19.97  LDD1812 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 19.97  LDD1812 
HIG1 domain family member 1A, mitochondrial (HIGD1A) LDTP13797 6.45  LDD1812 
HIG1 domain family member 1A, mitochondrial (HIGD1A) LDTP13797 6.45  LDD1812 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 7.26  LDD1812 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 7.26  LDD1812 
Large proline-rich protein BAG6 (BAG6) LDTP04094 10.27  LDD1812 
Large proline-rich protein BAG6 (BAG6) LDTP04094 10.27  LDD1812 
Large ribosomal subunit protein mL45 (MRPL45) LDTP15863 7.21  LDD1812 
Large ribosomal subunit protein mL45 (MRPL45) LDTP15863 7.21  LDD1812 
Mediator of RNA polymerase II transcription subunit 25 (MED25) LDTP07906 6.82  LDD1812 
Mediator of RNA polymerase II transcription subunit 25 (MED25) LDTP07906 6.82  LDD1812 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 24.42  LDD1812 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 24.42  LDD1812 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 30.27  LDD1812 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 30.27  LDD1812 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 13.00  LDD1812 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 13.00  LDD1812 
Nuclear inhibitor of protein phosphatase 1 (PPP1R8) LDTP05711 9.71  LDD1812 
Nuclear inhibitor of protein phosphatase 1 (PPP1R8) LDTP05711 9.71  LDD1812 
Nucleobindin-1 (NUCB1) LDTP05375 13.55  LDD1812 
Nucleobindin-1 (NUCB1) LDTP05375 13.55  LDD1812 
Nucleobindin-2 (NUCB2) LDTP05160 21.86  LDD1812 
Nucleobindin-2 (NUCB2) LDTP05160 21.86  LDD1812 
Nurim (NRM) LDTP08606 7.89  LDD1812 
Nurim (NRM) LDTP08606 7.89  LDD1812 
Optic atrophy 3 protein (OPA3) LDTP16006 9.25  LDD1812 
Optic atrophy 3 protein (OPA3) LDTP16006 9.25  LDD1812 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 6.54  LDD1812 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 6.54  LDD1812 
Protein CEBPZOS (CEBPZOS) LDTP18883 20.68  LDD1812 
Protein CEBPZOS (CEBPZOS) LDTP18883 20.68  LDD1812 
Protein CutA (CUTA) LDTP01075 10.20  LDD1812 
Protein CutA (CUTA) LDTP01075 10.20  LDD1812 
Protein FAM114A2 (FAM114A2) LDTP16080 9.99  LDD1812 
Protein FAM114A2 (FAM114A2) LDTP16080 9.99  LDD1812 
Protein FAM162A (FAM162A) LDTP10056 11.08  LDD1812 
Protein FAM162A (FAM162A) LDTP10056 11.08  LDD1812 
Protein MTSS 2 (MTSS2) LDTP07916 7.06  LDD1812 
Protein MTSS 2 (MTSS2) LDTP07916 7.06  LDD1812 
Reticulon-3 (RTN3) LDTP01522 12.04  LDD1812 
Reticulon-3 (RTN3) LDTP01522 12.04  LDD1812 
Reticulon-4 (RTN4) LDTP12412 8.40  LDD1812 
Reticulon-4 (RTN4) LDTP12412 8.40  LDD1812 
RNA polymerase II elongation factor ELL (ELL) LDTP04682 6.54  LDD1812 
RNA polymerase II elongation factor ELL (ELL) LDTP04682 6.54  LDD1812 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 7.46  LDD1812 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 7.46  LDD1812 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 6.59  LDD1812 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 6.59  LDD1812 
Splicing factor, suppressor of white-apricot homolog (SFSWAP) LDTP14822 9.32  LDD1812 
Splicing factor, suppressor of white-apricot homolog (SFSWAP) LDTP14822 9.32  LDD1812 
Synaptogyrin-2 (SYNGR2) LDTP00859 6.73  LDD1812 
Synaptogyrin-2 (SYNGR2) LDTP00859 6.73  LDD1812 
Syntaxin-18 (STX18) LDTP13086 8.34  LDD1812 
Syntaxin-18 (STX18) LDTP13086 8.34  LDD1812 
Tetraspanin-6 (TSPAN6) LDTP14458 17.15  LDD1812 
Tetraspanin-6 (TSPAN6) LDTP14458 17.15  LDD1812 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 6.63  LDD1812 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 6.63  LDD1812 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 7.73  LDD1812 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 7.73  LDD1812 
TraB domain-containing protein (TRABD) LDTP19963 7.41  LDD1812 
TraB domain-containing protein (TRABD) LDTP19963 7.41  LDD1812 
Transmembrane protein 209 (TMEM209) LDTP18272 12.38  LDD1812 
Transmembrane protein 209 (TMEM209) LDTP18272 12.38  LDD1812 
U3 small nucleolar RNA-associated protein NOL7 (NOL7) LDTP13633 7.26  LDD1812 
U3 small nucleolar RNA-associated protein NOL7 (NOL7) LDTP13633 7.26  LDD1812 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 20.68  LDD1812 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 20.68  LDD1812 
Vimentin (VIM) LDTP02297 6.32  LDD1812 
Vimentin (VIM) LDTP02297 6.32  LDD1812 
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⏷ Show the Full List of 96 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1812 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587