Details of the Probe

General Information of Probe

Probe ID
LDPC0466
Probe Name
C233
Probe Type
PAL-AfBPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 325.412
Lipid-water partition coefficient (xlogp) 3.5429
Rotatable Bond Count (rotbonds) 9
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C19H23N3O2
Canonical SMILES
[H]C#CC([H])([H])C([H])([H])C1(C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])c2c([H])c([H])c3c(c2[H])C([H])(C([H])([H])[H])C([H])(C([H])([H])[H])O3)N=N1
InChI
InChI=1S/C19H23N3O2/c1-4-5-9-19(21-22-19)10-8-18(23)20-12-15-6-7-17-16(11-15)13(2)14(3)24-17/h1,6-7,11,13-14H,5,8-10,12H2,2-3H3,(H,20,23)/t13-,14-/m1/s1
InChIKey
GEFOLMAVCDXJEY-ZIAGYGMSSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

124 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 18.77  LDD1906 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 12.38  LDD1906 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 48.50  LDD1906 
Abasic site processing protein HMCES (HMCES) LDTP10322 9.99  LDD1906 
Acid ceramidase (ASAH1) LDTP05905 18.13  LDD1906 
Acylglycerol kinase, mitochondrial (AGK) LDTP06905 8.63  LDD1906 
Adenosine 5'-monophosphoramidase HINT3 (HINT3) LDTP12415 9.65  LDD1906 
Adenosine kinase (ADK) LDTP04689 13.83  LDD1906 
ADP-ribosylation factor-like protein 1 (ARL1) LDTP03900 8.82  LDD1906 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 11.39  LDD1906 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 11.16  LDD1906 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 8.63  LDD1906 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 16.00  LDD1906 
Atlastin-2 (ATL2) LDTP09251 13.00  LDD1906 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 38.59  LDD1906 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 8.69  LDD1906 
ATPase GET3 (GET3) LDTP00836 9.58  LDD1906 
Atypical kinase COQ8A, mitochondrial (COQ8A) LDTP09285 24.76  LDD1906 
Atypical kinase COQ8B, mitochondrial (COQ8B) LDTP10201 11.96  LDD1906 
Beta-galactosidase (GLB1) LDTP02837 13.83  LDD1906 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 10.13  LDD1906 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 10.93  LDD1906 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 11.63  LDD1906 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 14.62  LDD1906 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 9.71  LDD1906 
Catechol O-methyltransferase (COMT) LDTP03145 8.82  LDD1906 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 19.43  LDD1906 
Ceramide glucosyltransferase (UGCG) LDTP06617 9.06  LDD1906 
Ceramide synthase 2 (CERS2) LDTP10329 14.12  LDD1906 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 23.75  LDD1906 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 30.91  LDD1906 
Cytochrome b5 type B (CYB5B) LDTP00697 16.11  LDD1906 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 9.92  LDD1906 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 14.83  LDD1906 
DCN1-like protein 5 (DCUN1D5) LDTP11199 12.91  LDD1906 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 36.76  LDD1906 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 9.65  LDD1906 
Delta(24)-sterol reductase (DHCR24) LDTP06375 13.64  LDD1906 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 11.39  LDD1906 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 9.19  LDD1906 
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) LDTP11259 9.99  LDD1906 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 11.08  LDD1906 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 21.26  LDD1906 
Endoplasmic reticulum metallopeptidase 1 (ERMP1) LDTP08017 11.79  LDD1906 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 9.65  LDD1906 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 14.52  LDD1906 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 9.85  LDD1906 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 23.75  LDD1906 
Farnesyl pyrophosphate synthase (FDPS) LDTP02721 9.78  LDD1906 
Glucose-6-phosphate 1-dehydrogenase (G6PD) LDTP02569 19.84  LDD1906 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 12.55  LDD1906 
Heme A synthase COX15 (COX15) LDTP07931 13.74  LDD1906 
Heme oxygenase 1 (HMOX1) LDTP02359 14.03  LDD1906 
Heme oxygenase 2 (HMOX2) LDTP03540 47.50  LDD1906 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 10.63  LDD1906 
Hexokinase-2 (HK2) LDTP04531 9.00  LDD1906 
Holocytochrome c-type synthase (HCCS) LDTP04581 26.91  LDD1906 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 10.93  LDD1906 
Ketosamine-3-kinase (FN3KRP) LDTP16025 12.21  LDD1906 
Lanosterol synthase (LSS) LDTP04183 9.00  LDD1906 
Large ribosomal subunit protein mL39 (MRPL39) LDTP12835 8.63  LDD1906 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 17.63  LDD1906 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 13.93  LDD1906 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 24.93  LDD1906 
Lysophosphatidylserine lipase ABHD12 (ABHD12) LDTP08799 9.58  LDD1906 
Lysophospholipid acyltransferase 5 (LPCAT3) LDTP07504 8.94  LDD1906 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 17.51  LDD1906 
Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) LDTP03858 9.71  LDD1906 
Lysosomal acid phosphatase (ACP2) LDTP02539 10.27  LDD1906 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 28.05  LDD1906 
Lysosomal protective protein (CTSA) LDTP02505 29.86  LDD1906 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 11.88  LDD1906 
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) LDTP02565 14.93  LDD1906 
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial (ALDH6A1) LDTP05346 13.36  LDD1906 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 29.86  LDD1906 
Minor histocompatibility antigen H13 (HM13) LDTP09396 13.74  LDD1906 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 11.88  LDD1906 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 14.93  LDD1906 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 8.63  LDD1906 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 67.65  LDD1906 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 15.78  LDD1906 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 23.92  LDD1906 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 11.16  LDD1906 
NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1) LDTP01219 10.20  LDD1906 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 26.35  LDD1906 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 8.82  LDD1906 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 14.32  LDD1906 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 25.11  LDD1906 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 20.53  LDD1906 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 30.70  LDD1906 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 45.25  LDD1906 
Palmitoyltransferase ZDHHC13 (ZDHHC13) LDTP08455 15.67  LDD1906 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 9.78  LDD1906 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 9.19  LDD1906 
Phospholipase A2 group XV (PLA2G15) LDTP09088 14.62  LDD1906 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 8.94  LDD1906 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 17.39  LDD1906 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 37.53  LDD1906 
Prostaglandin E synthase 3 (PTGES3) LDTP06338 13.27  LDD1906 
Prostaglandin reductase 3 (PTGR3) LDTP15422 67.18  LDD1906 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 24.08  LDD1906 
Proteasome subunit beta type-7 (PSMB7) LDTP10862 9.51  LDD1906 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 10.85  LDD1906 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 9.45  LDD1906 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 24.08  LDD1906 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 14.62  LDD1906 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 14.93  LDD1906 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 70.52  LDD1906 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 29.65  LDD1906 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 8.94  LDD1906 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 18.51  LDD1906 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 20.25  LDD1906 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 26.54  LDD1906 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 9.99  LDD1906 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 22.16  LDD1906 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 11.88  LDD1906 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 8.82  LDD1906 
Thioredoxin-like protein 1 (TXNL1) LDTP00758 15.45  LDD1906 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 11.79  LDD1906 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 14.22  LDD1906 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 39.67  LDD1906 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 33.13  LDD1906 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 28.44  LDD1906 
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (PDK1) LDTP06320 13.09  LDD1906 
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⏷ Show the Full List of 124 Enzyme
97 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 10.56  LDD1906 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 38.32  LDD1906 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 19.03  LDD1906 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 9.51  LDD1906 
ATP synthase subunit a (MT-ATP6) LDTP01804 33.36  LDD1906 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 45.57  LDD1906 
BRI3-binding protein (BRI3BP) LDTP15648 26.72  LDD1906 
Calcium uptake protein 1, mitochondrial (MICU1) LDTP11041 10.78  LDD1906 
Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) LDTP08469 11.88  LDD1906 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 8.94  LDD1906 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 72.50  LDD1906 
Derlin-1 (DERL1) LDTP11245 12.73  LDD1906 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 24.42  LDD1906 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 22.94  LDD1906 
Essential MCU regulator, mitochondrial (SMDT1) LDTP11927 19.43  LDD1906 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 8.75  LDD1906 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 10.85  LDD1906 
H(+)/Cl(-) exchange transporter 7 (CLCN7) LDTP04463 18.64  LDD1906 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 8.69  LDD1906 
Integral membrane protein 2B (ITM2B) LDTP13833 16.68  LDD1906 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 8.75  LDD1906 
Lysosome membrane protein 2 (SCARB2) LDTP06034 44.32  LDD1906 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 27.10  LDD1906 
Magnesium transporter protein 1 (MAGT1) LDTP11732 9.58  LDD1906 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 16.00  LDD1906 
Major facilitator superfamily domain-containing protein 8 (MFSD8) LDTP09261 21.71  LDD1906 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 11.00  LDD1906 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 13.64  LDD1906 
Metaxin-1 (MTX1) LDTP05900 19.43  LDD1906 
MFS-type transporter SLC18B1 (SLC18B1) LDTP07462 14.52  LDD1906 
MICOS complex subunit MIC26 (APOO) LDTP11250 11.08  LDD1906 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 9.32  LDD1906 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 16.22  LDD1906 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 10.93  LDD1906 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 20.39  LDD1906 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 10.06  LDD1906 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 10.41  LDD1906 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 33.59  LDD1906 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 31.34  LDD1906 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 12.55  LDD1906 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 14.62  LDD1906 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 10.78  LDD1906 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 10.93  LDD1906 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 9.92  LDD1906 
Mpv17-like protein 2 (MPV17L2) LDTP14952 25.63  LDD1906 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 13.93  LDD1906 
Nucleoporin NDC1 (NDC1) LDTP11213 14.83  LDD1906 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 11.88  LDD1906 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 8.82  LDD1906 
Peroxisomal biogenesis factor 3 (PEX3) LDTP04749 9.06  LDD1906 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 21.11  LDD1906 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 10.56  LDD1906 
Peroxisomal membrane protein PEX16 (PEX16) LDTP14181 17.51  LDD1906 
Prosaposin (PSAP) LDTP02215 24.08  LDD1906 
Protein ARV1 (ARV1) LDTP11812 10.78  LDD1906 
Protein FAM8A1 (FAM8A1) LDTP16190 9.99  LDD1906 
Protein GPR107 (GPR107) LDTP07236 16.45  LDD1906 
Protein GPR108 (GPR108) LDTP12383 35.51  LDD1906 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 11.24  LDD1906 
Protein tweety homolog 3 (TTYH3) LDTP11615 25.28  LDD1906 
Protein wntless homolog (WLS) LDTP07156 34.30  LDD1906 
Proton-coupled amino acid transporter 1 (SLC36A1) LDTP08016 21.86  LDD1906 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 25.81  LDD1906 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 30.91  LDD1906 
Sideroflexin-4 (SFXN4) LDTP07531 9.25  LDD1906 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 20.53  LDD1906 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 36.25  LDD1906 
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) LDTP10731 15.56  LDD1906 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 18.90  LDD1906 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 12.82  LDD1906 
Solute carrier family 35 member F1 (SLC35F1) LDTP15000 23.92  LDD1906 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 18.25  LDD1906 
Solute carrier family 41 member 3 (SLC41A3) LDTP10370 10.78  LDD1906 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 17.39  LDD1906 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 9.13  LDD1906 
Surfeit locus protein 4 (SURF4) LDTP00592 18.38  LDD1906 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 10.06  LDD1906 
Syntaxin-5 (STX5) LDTP05780 9.00  LDD1906 
Tetraspanin-3 (TSPAN3) LDTP16813 68.59  LDD1906 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 42.22  LDD1906 
Translocator protein (TSPO) LDTP03546 14.62  LDD1906 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 25.63  LDD1906 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 18.00  LDD1906 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 9.58  LDD1906 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 10.56  LDD1906 
Transmembrane protein 126A (TMEM126A) LDTP15948 24.76  LDD1906 
Transmembrane protein 160 (TMEM160) LDTP20002 18.25  LDD1906 
Transmembrane protein 199 (TMEM199) LDTP08881 25.81  LDD1906 
Transmembrane protein 205 (TMEM205) LDTP07667 16.00  LDD1906 
Transmembrane protein 230 (TMEM230) LDTP10065 8.63  LDD1906 
Transmembrane protein 87A (TMEM87A) LDTP15481 28.25  LDD1906 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 16.34  LDD1906 
Vang-like protein 1 (VANGL1) LDTP09288 11.71  LDD1906 
Vezatin (VEZT) LDTP12191 8.75  LDD1906 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 63.56  LDD1906 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 44.32  LDD1906 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 9.19  LDD1906 
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⏷ Show the Full List of 97 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Zinc finger protein 281 (ZNF281) LDTP13928 12.47  LDD1906 
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1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Leukocyte surface antigen CD47 (CD47) LDTP05572 10.78  LDD1906 
------------------------------------------------------------------------------------
79 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 13.09  LDD1906 
Apolipoprotein L2 (APOL2) LDTP11076 93.05  LDD1906 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 9.25  LDD1906 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 30.48  LDD1906 
Calumenin (CALU) LDTP00887 11.96  LDD1906 
Centrosomal protein 43 (CEP43) LDTP01652 26.17  LDD1906 
Clustered mitochondria protein homolog (CLUH) LDTP14486 26.17  LDD1906 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 17.15  LDD1906 
DnaJ homolog subfamily C member 11 (DNAJC11) LDTP12677 9.00  LDD1906 
Dynactin subunit 3 (DCTN3) LDTP01359 10.70  LDD1906 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 22.78  LDD1906 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 46.53  LDD1906 
Engulfment and cell motility protein 2 (ELMO2) LDTP10469 9.78  LDD1906 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 97.68  LDD1906 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 34.78  LDD1906 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 15.56  LDD1906 
General transcription factor IIF subunit 1 (GTF2F1) LDTP03729 11.96  LDD1906 
Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) LDTP00729 9.65  LDD1906 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 21.56  LDD1906 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 12.38  LDD1906 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 9.99  LDD1906 
HCLS1-associated protein X-1 (HAX1) LDTP00199 16.34  LDD1906 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 28.84  LDD1906 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 11.79  LDD1906 
Large proline-rich protein BAG6 (BAG6) LDTP04094 18.38  LDD1906 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 10.41  LDD1906 
Large ribosomal subunit protein mL64 (GADD45GIP1) LDTP09297 10.27  LDD1906 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 13.45  LDD1906 
Large ribosomal subunit protein uL24m (MRPL24) LDTP15687 8.69  LDD1906 
MAGUK p55 subfamily member 2 (MPP2) LDTP06068 8.88  LDD1906 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 24.25  LDD1906 
Membralin (TMEM259) LDTP14939 25.46  LDD1906 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 11.16  LDD1906 
Microtubule-associated protein RP/EB family member 2 (MAPRE2) LDTP06413 10.93  LDD1906 
Mitochondrial antiviral-signaling protein (MAVS) LDTP08058 13.09  LDD1906 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 22.78  LDD1906 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 18.90  LDD1906 
Neudesin (NENF) LDTP13630 11.00  LDD1906 
NLR family member X1 (NLRX1) LDTP08248 11.39  LDD1906 
Nucleobindin-2 (NUCB2) LDTP05160 30.70  LDD1906 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 16.68  LDD1906 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 17.03  LDD1906 
Optic atrophy 3 protein (OPA3) LDTP16006 19.29  LDD1906 
Peflin (PEF1) LDTP13167 10.13  LDD1906 
Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) LDTP11906 10.27  LDD1906 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 34.06  LDD1906 
Polyadenylate-binding protein-interacting protein 2 (PAIP2) LDTP11044 11.55  LDD1906 
Pre-mRNA 3'-end-processing factor FIP1 (FIP1L1) LDTP07655 11.96  LDD1906 
Protein ecdysoneless homolog (ECD) LDTP01711 11.39  LDD1906 
Protein FAM114A2 (FAM114A2) LDTP16080 18.00  LDD1906 
Protein FAM136A (FAM136A) LDTP18132 13.18  LDD1906 
Protein FAM162A (FAM162A) LDTP10056 58.89  LDD1906 
Protein jagunal homolog 1 (JAGN1) LDTP08904 9.06  LDD1906 
Protein LYRIC (MTDH) LDTP08224 21.41  LDD1906 
Protein misato homolog 1 (MSTO1) LDTP11239 9.32  LDD1906 
Protein SET (SET) LDTP05277 8.75  LDD1906 
Protein unc-119 homolog A (UNC119) LDTP05868 15.45  LDD1906 
Protein unc-119 homolog B (UNC119B) LDTP00105 9.65  LDD1906 
Protein YIF1A (YIF1A) LDTP01494 20.97  LDD1906 
RalBP1-associated Eps domain-containing protein 1 (REPS1) LDTP10203 9.99  LDD1906 
Refilin-B (RFLNB) LDTP17721 9.38  LDD1906 
Reticulocalbin-1 (RCN1) LDTP06352 18.25  LDD1906 
Reticulocalbin-2 (RCN2) LDTP06097 12.38  LDD1906 
Reticulon-3 (RTN3) LDTP01522 25.63  LDD1906 
Reticulon-4 (RTN4) LDTP12412 14.32  LDD1906 
RNA-binding protein 39 (RBM39) LDTP06128 9.25  LDD1906 
RUS family member 1 (RUSF1) LDTP10357 10.85  LDD1906 
Striatin (STRN) LDTP00875 11.24  LDD1906 
Synaptogyrin-2 (SYNGR2) LDTP00859 14.83  LDD1906 
Syntaxin-18 (STX18) LDTP13086 13.93  LDD1906 
Tetraspanin-6 (TSPAN6) LDTP14458 51.27  LDD1906 
Tetratricopeptide repeat protein 38 (TTC38) LDTP19372 16.00  LDD1906 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 17.15  LDD1906 
TraB domain-containing protein (TRABD) LDTP19963 12.47  LDD1906 
Transmembrane protein 209 (TMEM209) LDTP18272 14.32  LDD1906 
Trophoblast glycoprotein (TPBG) LDTP05960 8.69  LDD1906 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 15.35  LDD1906 
Wings apart-like protein homolog (WAPL) LDTP08094 10.63  LDD1906 
YEATS domain-containing protein 4 (YEATS4) LDTP01638 15.24  LDD1906 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1906 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587