Details of the Probe

General Information of Probe

Probe ID
LDPC0577
Probe Name
C356
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 347.365
Lipid-water partition coefficient (xlogp) 3.6158
Rotatable Bond Count (rotbonds) 9
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C18H19F2N3O2
Canonical SMILES
[H]C#CC([H])([H])C([H])([H])C1(C([H])([H])C([H])([H])C(=O)N([H])C2([H])C([H])([H])C2([H])c2c([H])c([H])c([H])c([H])c2OC([H])(F)F)N=N1
InChI
InChI=1S/C18H19F2N3O2/c1-2-3-9-18(22-23-18)10-8-16(24)21-14-11-13(14)12-6-4-5-7-15(12)25-17(19)20/h1,4-7,13-14,17H,3,8-11H2,(H,21,24)/t13-,14+/m0/s1
InChIKey
MDKNBDIOFWMPQZ-UONOGXRCSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

139 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 9.78  LDD2017 
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) LDTP02000 8.94  LDD2017 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 8.88  LDD2017 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 9.06  LDD2017 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 27.10  LDD2017 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 19.16  LDD2017 
Acid ceramidase (ASAH1) LDTP05905 14.12  LDD2017 
Acireductone dioxygenase (ADI1) LDTP11268 16.45  LDD2017 
Adenosine deaminase (ADA) LDTP01803 15.35  LDD2017 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 8.88  LDD2017 
ADP-dependent glucokinase (ADPGK) LDTP11127 10.85  LDD2017 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 12.13  LDD2017 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 8.82  LDD2017 
Alpha-galactosidase A (GLA) LDTP02141 7.94  LDD2017 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 11.08  LDD2017 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 8.82  LDD2017 
Atlastin-2 (ATL2) LDTP09251 8.51  LDD2017 
ATP-binding cassette sub-family C member 10 (ABCC10) LDTP07109 10.34  LDD2017 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 21.11  LDD2017 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 8.94  LDD2017 
Beta-1,3-galactosyltransferase 6 (B3GALT6) LDTP10530 8.28  LDD2017 
Beta-galactosidase (GLB1) LDTP02837 16.80  LDD2017 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 8.69  LDD2017 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 20.82  LDD2017 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 14.72  LDD2017 
Calcium-transporting ATPase type 2C member 1 (ATP2C1) LDTP05228 9.32  LDD2017 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 14.52  LDD2017 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 14.52  LDD2017 
Cartilage-associated protein (CRTAP) LDTP01300 7.94  LDD2017 
Catechol O-methyltransferase (COMT) LDTP03145 9.25  LDD2017 
Ceramide glucosyltransferase (UGCG) LDTP06617 15.24  LDD2017 
Ceramide synthase 1 (CERS1) LDTP03394 11.71  LDD2017 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 9.99  LDD2017 
Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (CSGALNACT2) LDTP08933 11.16  LDD2017 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 9.51  LDD2017 
COP9 signalosome complex subunit 6 (COPS6) LDTP07966 8.11  LDD2017 
Cyclin-dependent kinase 9 (CDK9) LDTP04384 8.63  LDD2017 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 13.09  LDD2017 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 20.39  LDD2017 
Cytochrome b5 type B (CYB5B) LDTP00697 68.12  LDD2017 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 8.22  LDD2017 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 11.24  LDD2017 
DCN1-like protein 4 (DCUN1D4) LDTP09799 9.13  LDD2017 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 14.62  LDD2017 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 9.32  LDD2017 
Delta(14)-sterol reductase TM7SF2 (TM7SF2) LDTP01389 8.00  LDD2017 
Delta(24)-sterol reductase (DHCR24) LDTP06375 11.63  LDD2017 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 11.47  LDD2017 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 9.13  LDD2017 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 8.00  LDD2017 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 16.34  LDD2017 
E3 ubiquitin-protein ligase RNF14 (RNF14) LDTP13154 8.22  LDD2017 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 9.58  LDD2017 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 8.63  LDD2017 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 14.12  LDD2017 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 20.39  LDD2017 
Ethanolamine kinase 1 (ETNK1) LDTP12197 14.83  LDD2017 
Exonuclease 1 (EXO1) LDTP13751 9.32  LDD2017 
Exosome complex component RRP43 (EXOSC8) LDTP10110 8.57  LDD2017 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 16.00  LDD2017 
Ferritin heavy chain (FTH1) LDTP01974 9.19  LDD2017 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 9.58  LDD2017 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 12.91  LDD2017 
Glycerophosphodiester phosphodiesterase 1 (GDE1) LDTP12886 12.38  LDD2017 
Heme oxygenase 1 (HMOX1) LDTP02359 23.26  LDD2017 
Heme oxygenase 2 (HMOX2) LDTP03540 53.45  LDD2017 
Histone-lysine N-methyltransferase SMYD3 (SMYD3) LDTP12020 16.11  LDD2017 
Holocytochrome c-type synthase (HCCS) LDTP04581 9.00  LDD2017 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 17.75  LDD2017 
L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) LDTP12105 8.34  LDD2017 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 10.48  LDD2017 
Lanosterol synthase (LSS) LDTP04183 8.88  LDD2017 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 12.47  LDD2017 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 33.82  LDD2017 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 8.11  LDD2017 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 55.33  LDD2017 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 7.94  LDD2017 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 13.45  LDD2017 
Lysosomal acid phosphatase (ACP2) LDTP02539 9.85  LDD2017 
Lysosomal alpha-glucosidase (GAA) LDTP02486 11.88  LDD2017 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 26.35  LDD2017 
Lysosomal protective protein (CTSA) LDTP02505 10.06  LDD2017 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 22.32  LDD2017 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 11.08  LDD2017 
Minor histocompatibility antigen H13 (HM13) LDTP09396 9.38  LDD2017 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 8.69  LDD2017 
N-alpha-acetyltransferase 40 (NAA40) LDTP08265 28.25  LDD2017 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 25.81  LDD2017 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 9.19  LDD2017 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 32.90  LDD2017 
NADH dehydrogenase 1 beta subcomplex subunit 8, mitochondrial (NDUFB8) LDTP01515 15.24  LDD2017 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 12.30  LDD2017 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 11.55  LDD2017 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 20.82  LDD2017 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 29.65  LDD2017 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 14.32  LDD2017 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 19.84  LDD2017 
Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) LDTP01562 9.51  LDD2017 
Peroxisomal trans-2-enoyl-CoA reductase (PECR) LDTP11437 8.00  LDD2017 
Phenylalanine--tRNA ligase beta subunit (FARSB) LDTP12586 12.30  LDD2017 
Phospholipase A2 group XV (PLA2G15) LDTP09088 18.64  LDD2017 
Pirin (PIR) LDTP00325 44.63  LDD2017 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 9.45  LDD2017 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 24.42  LDD2017 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 20.11  LDD2017 
Prolyl 4-hydroxylase subunit alpha-2 (P4HA2) LDTP00645 8.22  LDD2017 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 8.22  LDD2017 
Prostaglandin reductase 3 (PTGR3) LDTP15422 19.43  LDD2017 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 19.84  LDD2017 
Protein O-GlcNAcase (OGA) LDTP00988 13.74  LDD2017 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 17.51  LDD2017 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 9.06  LDD2017 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 17.63  LDD2017 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 29.04  LDD2017 
Retinol dehydrogenase 13 (RDH13) LDTP09061 9.06  LDD2017 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 8.22  LDD2017 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 8.11  LDD2017 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 8.75  LDD2017 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 9.13  LDD2017 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 8.88  LDD2017 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 10.70  LDD2017 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 7.78  LDD2017 
Soluble calcium-activated nucleotidase 1 (CANT1) LDTP09620 8.57  LDD2017 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 11.31  LDD2017 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 19.70  LDD2017 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 13.55  LDD2017 
Squalene monooxygenase (SQLE) LDTP06142 9.58  LDD2017 
Squalene synthase (FDFT1) LDTP03842 12.13  LDD2017 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 11.63  LDD2017 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 8.06  LDD2017 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 7.94  LDD2017 
Tubulin--tyrosine ligase-like protein 12 (TTLL12) LDTP06067 7.84  LDD2017 
UbiA prenyltransferase domain-containing protein 1 (UBIAD1) LDTP14189 10.78  LDD2017 
Ubiquitin carboxyl-terminal hydrolase 28 (USP28) LDTP10785 9.00  LDD2017 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 11.79  LDD2017 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 8.34  LDD2017 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 31.56  LDD2017 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 9.99  LDD2017 
Xaa-Pro aminopeptidase 3 (XPNPEP3) LDTP12420 8.22  LDD2017 
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⏷ Show the Full List of 139 Enzyme
76 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 8.22  LDD2017 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 11.47  LDD2017 
Amyloid-beta precursor protein (APP) LDTP02071 11.31  LDD2017 
ATP synthase subunit a (MT-ATP6) LDTP01804 32.67  LDD2017 
ATP synthase subunit e, mitochondrial (ATP5ME) LDTP14717 7.94  LDD2017 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 27.10  LDD2017 
Autophagy-related protein 9A (ATG9A) LDTP08030 10.06  LDD2017 
BOS complex subunit NCLN (NCLN) LDTP10036 8.88  LDD2017 
BRI3-binding protein (BRI3BP) LDTP15648 16.80  LDD2017 
Calcium uptake protein 1, mitochondrial (MICU1) LDTP11041 8.51  LDD2017 
Calcium uptake protein 2, mitochondrial (MICU2) LDTP08673 11.24  LDD2017 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 10.13  LDD2017 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 57.28  LDD2017 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 8.75  LDD2017 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 34.78  LDD2017 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 19.43  LDD2017 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 8.57  LDD2017 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 8.34  LDD2017 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 13.18  LDD2017 
Heme transporter FLVCR1 (FLVCR1) LDTP14178 9.32  LDD2017 
Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) LDTP01100 11.47  LDD2017 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 8.46  LDD2017 
Lysosome membrane protein 2 (SCARB2) LDTP06034 35.75  LDD2017 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 7.94  LDD2017 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 8.00  LDD2017 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 13.64  LDD2017 
Metal cation symporter ZIP14 (SLC39A14) LDTP06293 9.92  LDD2017 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 8.88  LDD2017 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 8.46  LDD2017 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 19.70  LDD2017 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 9.78  LDD2017 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 99.73  LDD2017 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 99.73  LDD2017 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 9.58  LDD2017 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 14.52  LDD2017 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 8.46  LDD2017 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 11.08  LDD2017 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 11.79  LDD2017 
Mpv17-like protein 2 (MPV17L2) LDTP14952 9.00  LDD2017 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 10.93  LDD2017 
Nucleoporin NDC1 (NDC1) LDTP11213 9.85  LDD2017 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 10.27  LDD2017 
Peroxisomal biogenesis factor 3 (PEX3) LDTP04749 8.63  LDD2017 
Prosaposin (PSAP) LDTP02215 29.86  LDD2017 
Protein FAM8A1 (FAM8A1) LDTP16190 9.19  LDD2017 
Protein spinster homolog 1 (SPNS1) LDTP11844 14.32  LDD2017 
Protein tweety homolog 3 (TTYH3) LDTP11615 28.05  LDD2017 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 11.47  LDD2017 
Reticulon-1 (RTN1) LDTP06633 28.64  LDD2017 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 16.56  LDD2017 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 9.06  LDD2017 
Sideroflexin-4 (SFXN4) LDTP07531 17.51  LDD2017 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 18.38  LDD2017 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 34.54  LDD2017 
Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15) LDTP11826 8.82  LDD2017 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 10.93  LDD2017 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 8.40  LDD2017 
Sorting nexin-5 (SNX5) LDTP14174 8.06  LDD2017 
SUN domain-containing protein 2 (SUN2) LDTP13256 8.82  LDD2017 
Tetraspanin-10 (TSPAN10) LDTP15967 31.34  LDD2017 
Tetraspanin-3 (TSPAN3) LDTP16813 22.32  LDD2017 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 16.80  LDD2017 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 25.63  LDD2017 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 8.88  LDD2017 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 9.58  LDD2017 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 15.35  LDD2017 
Transmembrane protein 126A (TMEM126A) LDTP15948 16.11  LDD2017 
Transmembrane protein 160 (TMEM160) LDTP20002 21.56  LDD2017 
Transmembrane protein 199 (TMEM199) LDTP08881 15.67  LDD2017 
Transmembrane protein 230 (TMEM230) LDTP10065 9.71  LDD2017 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 34.06  LDD2017 
V-type proton ATPase subunit S1 (ATP6AP1) LDTP06499 8.06  LDD2017 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 31.12  LDD2017 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 42.81  LDD2017 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 8.40  LDD2017 
Zinc transporter 7 (SLC30A7) LDTP09180 12.30  LDD2017 
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⏷ Show the Full List of 76 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 9.25  LDD2017 
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1 GPCR Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Membrane progestin receptor alpha (PAQR7) LDTP15303 18.90  LDD2017 
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76 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 8.88  LDD2017 
Adapter molecule crk (CRK) LDTP04091 8.82  LDD2017 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 10.63  LDD2017 
Apolipoprotein L2 (APOL2) LDTP11076 18.13  LDD2017 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 9.38  LDD2017 
c-Myc-binding protein (MYCBP) LDTP10857 8.94  LDD2017 
Centrin-2 (CETN2) LDTP03926 9.13  LDD2017 
Centrosomal protein 43 (CEP43) LDTP01652 11.88  LDD2017 
Clustered mitochondria protein homolog (CLUH) LDTP14486 14.52  LDD2017 
Cold-inducible RNA-binding protein (CIRBP) LDTP06022 7.89  LDD2017 
Complex I intermediate-associated protein 30, mitochondrial (NDUFAF1) LDTP13954 7.89  LDD2017 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 39.67  LDD2017 
DNA replication complex GINS protein PSF2 (GINS2) LDTP13802 10.27  LDD2017 
Dynactin subunit 3 (DCTN3) LDTP01359 8.17  LDD2017 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 12.04  LDD2017 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 53.08  LDD2017 
Engulfment and cell motility protein 2 (ELMO2) LDTP10469 8.75  LDD2017 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 18.77  LDD2017 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 9.00  LDD2017 
Glutamate-rich WD repeat-containing protein 1 (GRWD1) LDTP11058 9.78  LDD2017 
Golgi apparatus protein 1 (GLG1) LDTP09920 8.88  LDD2017 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 9.58  LDD2017 
HAUS augmin-like complex subunit 1 (HAUS1) LDTP10184 9.78  LDD2017 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 9.38  LDD2017 
HCLS1-associated protein X-1 (HAX1) LDTP00199 15.03  LDD2017 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 9.58  LDD2017 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 10.78  LDD2017 
Large ribosomal subunit protein mL64 (GADD45GIP1) LDTP09297 8.88  LDD2017 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 12.73  LDD2017 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 58.08  LDD2017 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 7.89  LDD2017 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 8.82  LDD2017 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 29.86  LDD2017 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 73.01  LDD2017 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 26.72  LDD2017 
Negative elongation factor C/D (NELFCD) LDTP08594 14.93  LDD2017 
Neudesin (NENF) LDTP13630 15.89  LDD2017 
Neuferricin (CYB5D2) LDTP15623 16.00  LDD2017 
Nucleobindin-1 (NUCB1) LDTP05375 24.08  LDD2017 
Nucleobindin-2 (NUCB2) LDTP05160 49.87  LDD2017 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 7.94  LDD2017 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 8.17  LDD2017 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 9.19  LDD2017 
Optic atrophy 3 protein (OPA3) LDTP16006 11.16  LDD2017 
Oxysterol-binding protein-related protein 6 (OSBPL6) LDTP11533 15.03  LDD2017 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 9.45  LDD2017 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 55.33  LDD2017 
Prohibitin-2 (PHB2) LDTP10924 7.89  LDD2017 
Protein FAM114A2 (FAM114A2) LDTP16080 18.25  LDD2017 
Protein FAM162A (FAM162A) LDTP10056 14.52  LDD2017 
Protein Hook homolog 2 (HOOK2) LDTP10255 14.83  LDD2017 
Protein LYRIC (MTDH) LDTP08224 10.34  LDD2017 
Protein misato homolog 1 (MSTO1) LDTP11239 7.78  LDD2017 
Protein SET (SET) LDTP05277 8.34  LDD2017 
Protein unc-119 homolog A (UNC119) LDTP05868 10.85  LDD2017 
Protein unc-119 homolog B (UNC119B) LDTP00105 21.86  LDD2017 
Protein YIF1A (YIF1A) LDTP01494 8.88  LDD2017 
Rab9 effector protein with kelch motifs (RABEPK) LDTP08130 9.71  LDD2017 
Rap guanine nucleotide exchange factor 2 (RAPGEF2) LDTP14058 8.00  LDD2017 
Reticulocalbin-2 (RCN2) LDTP06097 10.56  LDD2017 
Reticulon-3 (RTN3) LDTP01522 24.25  LDD2017 
Reticulon-4 (RTN4) LDTP12412 14.12  LDD2017 
Reticulophagy regulator 2 (RETREG2) LDTP09080 9.00  LDD2017 
RNA-binding protein 3 (RBM3) LDTP05226 8.94  LDD2017 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 10.48  LDD2017 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 8.00  LDD2017 
Synaptogyrin-2 (SYNGR2) LDTP00859 13.36  LDD2017 
Syntaxin-18 (STX18) LDTP13086 11.63  LDD2017 
Tetraspanin-6 (TSPAN6) LDTP14458 14.12  LDD2017 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 10.56  LDD2017 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 17.63  LDD2017 
TraB domain-containing protein (TRABD) LDTP19963 14.72  LDD2017 
Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) LDTP15634 10.85  LDD2017 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 28.84  LDD2017 
Vacuolar protein sorting-associated protein 51 homolog (VPS51) LDTP13338 9.00  LDD2017 
Vimentin (VIM) LDTP02297 8.22  LDD2017 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD2017 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587