Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C055  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 146 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01769  Dihydrofolate reductase (DHFR) 99.7
 LDTP11273  N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) 99.7
 LDTP00832  NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) 77.2
 LDTP00486  Cytochrome b-c1 complex subunit 8 (UQCRQ) 63.1
 LDTP19745  ADP-ribosylation factor-like protein 10 (ARL10) 60.5
 LDTP12253  Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) 57.7
 LDTP08790  Mitochondrial cardiolipin hydrolase (PLD6) 56.5
 LDTP03842  Squalene synthase (FDFT1) 56.5
 LDTP11127  ADP-dependent glucokinase (ADPGK) 54.6
 LDTP13189  Cytochrome b-c1 complex subunit 9 (UQCR10) 51.3
 LDTP00697  Cytochrome b5 type B (CYB5B) 50.9
 LDTP06618  ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) 49.9
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 49.5
 LDTP16040  Glyoxalase domain-containing protein 4 (GLOD4) 47.5
 LDTP04689  Adenosine kinase (ADK) 45.6
 LDTP15328  Dolichyldiphosphatase 1 (DOLPP1) 40.8
 LDTP08385  NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) 40.5
 LDTP03540  Heme oxygenase 2 (HMOX2) 39.7
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 39.4
 LDTP02359  Heme oxygenase 1 (HMOX1) 38.1
 LDTP10329  Ceramide synthase 2 (CERS2) 35.8
 LDTP03394  Ceramide synthase 1 (CERS1) 34.3
 LDTP14218  Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) 32.9
 LDTP10188  FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) 32.7
 LDTP17410  Cytochrome P450 20A1 (CYP20A1) 31.1
 LDTP08538  DCN1-like protein 3 (DCUN1D3) 31.1
 LDTP02505  Lysosomal protective protein (CTSA) 31.1
 LDTP00575  Glutathione S-transferase A4 (GSTA4) 30.9
 LDTP01982  NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) 30.5
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 29.2
 LDTP09096  Carbohydrate sulfotransferase 14 (CHST14) 29.2
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 28.8
 LDTP01462  Endonuclease domain-containing 1 protein (ENDOD1) 27.7
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 27.1
 LDTP03418  Proteasome subunit beta type-6 (PSMB6) 26.9
 LDTP06333  Serum paraoxonase/arylesterase 2 (PON2) 26.9
 LDTP12873  CDGSH iron-sulfur domain-containing protein 1 (CISD1) 26.7
 LDTP01065  E3 ubiquitin-protein ligase TRIM13 (TRIM13) 26.2
 LDTP00907  Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) 26.2
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 24.9
 LDTP06750  Prolyl 3-hydroxylase 1 (P3H1) 24.9
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 24.9
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 24.9
 LDTP08532  Inositol 1,4,5-trisphosphate receptor-interacting protein (ITPRIP) 23.9
 LDTP12639  1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) 23.8
 LDTP08455  Palmitoyltransferase ZDHHC13 (ZDHHC13) 22.9
 LDTP13486  Long-chain-fatty-acid--CoA ligase 6 (ACSL6) 22.8
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 22.2
 LDTP01773  Cytochrome c oxidase subunit 2 (MT-CO2) 21.9
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 21.0
 LDTP10020  Ras-related protein Rab-24 (RAB24) 20.8
 LDTP12720  Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) 20.4
 LDTP06477  Methylsterol monooxygenase 1 (MSMO1) 20.3
 LDTP00462  Branched-chain alpha-ketoacid dehydrogenase kinase (BCKDK) 20.1
 LDTP07931  Heme A synthase COX15 (COX15) 19.8
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 19.3
 LDTP06617  Ceramide glucosyltransferase (UGCG) 19.3
 LDTP01219  NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1) 19.3
 LDTP06905  Acylglycerol kinase, mitochondrial (AGK) 18.8
 LDTP09031  Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGNT2) 18.5
 LDTP01513  NADH dehydrogenase 1 alpha subcomplex subunit 3 (NDUFA3) 18.3
 LDTP11178  Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) 18.1
 LDTP10550  Dehydrogenase/reductase SDR family member 1 (DHRS1) 17.9
 LDTP08859  Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) 17.9
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 17.8
 LDTP01613  Sphingosine-1-phosphate lyase 1 (SGPL1) 17.8
 LDTP09799  DCN1-like protein 4 (DCUN1D4) 17.5
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 17.4
 LDTP05476  3-ketodihydrosphingosine reductase (KDSR) 17.1
 LDTP12420  Xaa-Pro aminopeptidase 3 (XPNPEP3) 17.0
 LDTP03680  DNA replication licensing factor MCM4 (MCM4) 16.9
 LDTP10182  TLC domain-containing protein 1 (TLCD1) 16.7
 LDTP12960  [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP1) 16.7
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 16.6
 LDTP01803  Adenosine deaminase (ADA) 16.1
 LDTP18087  Dephospho-CoA kinase domain-containing protein (DCAKD) 15.9
 LDTP14276  NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) 15.9
 LDTP06150  DNA replication licensing factor MCM6 (MCM6) 15.5
 LDTP10785  Ubiquitin carboxyl-terminal hydrolase 28 (USP28) 15.5
 LDTP04581  Holocytochrome c-type synthase (HCCS) 15.3
 LDTP12681  ATPase family AAA domain-containing protein 3A (ATAD3A) 15.2
 LDTP10981  Mitochondrial intermediate peptidase (MIPEP) 15.1
 LDTP01502  NADH dehydrogenase 1 beta subcomplex subunit 6 (NDUFB6) 14.9
 LDTP14030  V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) 14.8
 LDTP05128  Glutathione S-transferase omega-1 (GSTO1) 14.7
 LDTP14264  Choline/ethanolaminephosphotransferase 1 (CEPT1) 14.5
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 14.5
 LDTP05758  S-methyl-5'-thioadenosine phosphorylase (MTAP) 14.5
 LDTP08728  Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) 14.5
 LDTP09188  Lysophosphatidylcholine acyltransferase 1 (LPCAT1) 14.4
 LDTP15480  Prenylcysteine oxidase-like (PCYOX1L) 14.3
 LDTP00988  Protein O-GlcNAcase (OGA) 14.0
 LDTP03145  Catechol O-methyltransferase (COMT) 13.9
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 13.9
 LDTP11199  DCN1-like protein 5 (DCUN1D5) 13.8
 LDTP07003  Presequence protease, mitochondrial (PITRM1) 13.8
 LDTP12415  Adenosine 5'-monophosphoramidase HINT3 (HINT3) 13.7
 LDTP13220  Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) 13.7
 LDTP11852  Presenilin-associated rhomboid-like protein, mitochondrial (PARL) 13.6
 LDTP12959  NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) 13.5
 LDTP00831  NADH dehydrogenase 1 beta subcomplex subunit 5, mitochondrial (NDUFB5) 13.5
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 13.5
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) 13.5
 LDTP07756  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (HACD2) 13.4
 LDTP00994  Beta-1,4-galactosyltransferase 3 (B4GALT3) 13.3
 LDTP13491  E3 ubiquitin-protein ligase AMFR (AMFR) 13.3
 LDTP12197  Ethanolamine kinase 1 (ETNK1) 13.3
 LDTP04456  Ubiquitin carboxyl-terminal hydrolase 11 (USP11) 13.3
 LDTP02589  Cyclin-dependent kinase 4 (CDK4) 13.2
 LDTP00877  Protein SCO2 homolog, mitochondrial (SCO2) 13.2
 LDTP12490  Sphingosine kinase 2 (SPHK2) 13.2
 LDTP12470  GTP-binding protein SAR1a (SAR1A) 13.1
 LDTP04531  Hexokinase-2 (HK2) 13.1
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 13.0
 LDTP00758  Thioredoxin-like protein 1 (TXNL1) 13.0
 LDTP06901  Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) 13.0
 LDTP06977  GPI ethanolamine phosphate transferase 2 (PIGG) 12.9
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 12.9
 LDTP14189  UbiA prenyltransferase domain-containing protein 1 (UBIAD1) 12.8
 LDTP03900  ADP-ribosylation factor-like protein 1 (ARL1) 12.7
 LDTP06200  Delta(14)-sterol reductase LBR (LBR) 12.7
 LDTP05029  Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) 12.7
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 12.7
 LDTP03608  RAC-beta serine/threonine-protein kinase (AKT2) 12.6
 LDTP13154  E3 ubiquitin-protein ligase RNF14 (RNF14) 12.6
 LDTP06501  Ras-related protein Rab-11B (RAB11B) 12.5
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 12.4
 LDTP12908  Ubiquinone biosynthesis O-methyltransferase, mitochondrial (COQ3) 12.4
 LDTP01743  NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) 12.3
 LDTP05624  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) 12.3
 LDTP12040  Prostaglandin E synthase 2 (PTGES2) 12.3
 LDTP12868  Endoplasmic reticulum aminopeptidase 1 (ERAP1) 12.2
 LDTP17305  Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) 12.2
 LDTP19851  Isochorismatase domain-containing protein 1 (ISOC1) 12.2
 LDTP00950  Dynamin-like 120 kDa protein, mitochondrial (OPA1) 12.1
 LDTP08082  L-xylulose reductase (DCXR) 12.1
 LDTP03854  Vitamin K-dependent gamma-carboxylase (GGCX) 12.1
 LDTP05724  Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) 12.0
 LDTP08323  Lon protease homolog 2, peroxisomal (LONP2) 12.0
 LDTP01687  Apoptosis-inducing factor 1, mitochondrial (AIFM1) 12.0
 LDTP05920  Calcium/calmodulin-dependent protein kinase type II subunit gamma (CAMK2G) 11.9
 LDTP04569  Geranylgeranyl transferase type-2 subunit beta (RABGGTB) 11.9
 LDTP00497  Cyclin-G-associated kinase (GAK) 11.8
 LDTP01335  Protein SCO1 homolog, mitochondrial (SCO1) 11.7
 LDTP10320  tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (TRMT61A) 11.7
 LDTP06142  Squalene monooxygenase (SQLE) 11.6
Transporter and channel
Click to Show/Hide to Show 112 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP02724  Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) 99.7
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 99.7
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 99.7
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 83.3
 LDTP11927  Essential MCU regulator, mitochondrial (SMDT1) 79.9
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 78.2
 LDTP01804  ATP synthase subunit a (MT-ATP6) 73.0
 LDTP20002  Transmembrane protein 160 (TMEM160) 66.7
 LDTP15948  Transmembrane protein 126A (TMEM126A) 64.0
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 64.0
 LDTP05900  Metaxin-1 (MTX1) 48.2
 LDTP08881  Transmembrane protein 199 (TMEM199) 46.9
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 46.5
 LDTP05305  Large neutral amino acids transporter small subunit 1 (SLC7A5) 45.9
 LDTP15648  BRI3-binding protein (BRI3BP) 41.6
 LDTP11245  Derlin-1 (DERL1) 39.4
 LDTP03546  Translocator protein (TSPO) 39.4
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 39.1
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 35.3
 LDTP07236  Protein GPR107 (GPR107) 35.3
 LDTP13983  Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) 33.6
 LDTP06426  Translocating chain-associated membrane protein 1 (TRAM1) 33.1
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 32.2
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 30.5
 LDTP12383  Protein GPR108 (GPR108) 29.9
 LDTP08878  ER membrane protein complex subunit 5 (MMGT1) 29.7
 LDTP17682  Zinc transporter ZIP11 (SLC39A11) 29.7
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 29.2
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) 28.8
 LDTP08981  Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) 28.6
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 27.7
 LDTP04789  Synaptojanin-2-binding protein (SYNJ2BP) 27.3
 LDTP09180  Zinc transporter 7 (SLC30A7) 27.3
 LDTP16813  Tetraspanin-3 (TSPAN3) 25.5
 LDTP10065  Transmembrane protein 230 (TMEM230) 24.9
 LDTP14099  Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) 24.8
 LDTP18459  StAR-related lipid transfer protein 7, mitochondrial (STARD7) 24.6
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 24.1
 LDTP08279  Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42) 22.3
 LDTP18153  Major facilitator superfamily domain-containing protein 3 (MFSD3) 22.0
 LDTP11213  Nucleoporin NDC1 (NDC1) 21.6
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 21.0
 LDTP15481  Transmembrane protein 87A (TMEM87A) 20.4
 LDTP09968  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) 20.4
 LDTP09328  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) 20.0
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 20.0
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 19.8
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 19.7
 LDTP04707  Protein SEC13 homolog (SEC13) 19.6
 LDTP15733  Solute carrier family 25 member 44 (SLC25A44) 19.4
 LDTP02256  Amino acid transporter heavy chain SLC3A2 (SLC3A2) 19.3
 LDTP09278  Multiple coagulation factor deficiency protein 2 (MCFD2) 19.0
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 18.8
 LDTP04592  Monocarboxylate transporter 1 (SLC16A1) 18.1
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 17.9
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 17.9
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 17.8
 LDTP11116  45 kDa calcium-binding protein (SDF4) 17.0
 LDTP16069  Peroxisomal membrane protein 2 (PXMP2) 17.0
 LDTP16190  Protein FAM8A1 (FAM8A1) 16.8
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 16.7
 LDTP00208  AP-4 complex subunit mu-1 (AP4M1) 16.6
 LDTP14682  Translocon-associated protein subunit beta (SSR2) 16.6
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 16.0
 LDTP06275  Lysosomal-associated transmembrane protein 4A (LAPTM4A) 15.9
 LDTP11162  Solute carrier family 25 member 33 (SLC25A33) 15.9
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 15.8
 LDTP01060  PRA1 family protein 2 (PRAF2) 15.5
 LDTP12207  Putative divalent cation/proton antiporter TMEM165 (TMEM165) 15.5
 LDTP09288  Vang-like protein 1 (VANGL1) 15.3
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 15.2
 LDTP00592  Surfeit locus protein 4 (SURF4) 15.2
 LDTP11406  Transmembrane protein 59 (TMEM59) 15.2
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 14.9
 LDTP11250  MICOS complex subunit MIC26 (APOO) 14.9
 LDTP14717  ATP synthase subunit e, mitochondrial (ATP5ME) 14.8
 LDTP06945  Sigma intracellular receptor 2 (TMEM97) 14.8
 LDTP11812  Protein ARV1 (ARV1) 14.6
 LDTP07156  Protein wntless homolog (WLS) 14.5
 LDTP10343  Vacuole membrane protein 1 (VMP1) 14.4
 LDTP01542  Golgi SNAP receptor complex member 1 (GOSR1) 14.3
 LDTP12636  Lysosomal cobalamin transport escort protein LMBD1 (LMBRD1) 14.3
 LDTP10669  Melanoma inhibitory activity protein 2 (MIA2) 14.3
 LDTP01671  STARD3 N-terminal-like protein (STARD3NL) 14.2
 LDTP09515  Importin-4 (IPO4) 14.0
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 14.0
 LDTP00865  Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) 13.9
 LDTP14200  Mitochondrial ornithine transporter 1 (SLC25A15) 13.9
 LDTP08469  Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) 13.7
 LDTP11095  Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) 13.7
 LDTP05662  Cell division cycle protein 20 homolog (CDC20) 13.6
 LDTP01056  Coiled-coil domain-containing protein 22 (CCDC22) 13.5
 LDTP05511  Cytoskeleton-associated protein 4 (CKAP4) 13.4
 LDTP12738  Ceroid-lipofuscinosis neuronal protein 6 (CLN6) 13.3
 LDTP03104  V-type proton ATPase subunit B, brain isoform (ATP6V1B2) 13.3
 LDTP07667  Transmembrane protein 205 (TMEM205) 13.0
 LDTP12210  Mitochondrial thiamine pyrophosphate carrier (SLC25A19) 12.7
 LDTP13661  Sorting nexin-6 (SNX6) 12.7
 LDTP02215  Prosaposin (PSAP) 12.5
 LDTP00547  Secretory carrier-associated membrane protein 2 (SCAMP2) 12.4
 LDTP07439  Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) 12.2
 LDTP05236  Phosphatidylinositol transfer protein alpha isoform (PITPNA) 12.1
 LDTP12331  Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) 12.0
 LDTP01309  Renin receptor (ATP6AP2) 12.0
 LDTP09202  Nucleoporin Nup43 (NUP43) 12.0
 LDTP13943  Thioredoxin-related transmembrane protein 2 (TMX2) 12.0
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10) 12.0
 LDTP15979  Transmembrane protein 245 (TMEM245) 12.0
 LDTP00010  Intraflagellar transport protein 56 (IFT56) 11.7
 LDTP09203  Nucleoporin Nup37 (NUP37) 11.7
 LDTP10754  Pannexin-1 (PANX1) 11.7
 LDTP00262  Acetyl-coenzyme A transporter 1 (SLC33A1) 11.6
Transcription factor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10501  DnaJ homolog subfamily C member 1 (DNAJC1) 20.0
GPCR
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15303  Membrane progestin receptor alpha (PAQR7) 28.6
Immunoglobulin
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03538  HLA class I histocompatibility antigen, alpha chain F (HLA-F) 26.7
 LDTP14205  Neuroplastin (NPTN) 18.1
 LDTP03772  Basigin (BSG) 15.6
Other
Click to Show/Hide to Show 120 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10775  Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) 99.7
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 99.7
 LDTP15420  Mitochondrial import receptor subunit TOM5 homolog (TOMM5) 99.7
 LDTP15634  Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) 92.4
 LDTP16099  p53 and DNA damage-regulated protein 1 (PDRG1) 79.9
 LDTP19859  Small integral membrane protein 12 (SMIM12) 76.6
 LDTP08154  Large ribosomal subunit protein uL10m (MRPL10) 70.0
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 67.6
 LDTP18883  Protein CEBPZOS (CEBPZOS) 54.2
 LDTP05375  Nucleobindin-1 (NUCB1) 49.9
 LDTP01522  Reticulon-3 (RTN3) 47.8
 LDTP10056  Protein FAM162A (FAM162A) 45.3
 LDTP11076  Apolipoprotein L2 (APOL2) 43.7
 LDTP14458  Tetraspanin-6 (TSPAN6) 41.4
 LDTP03678  ER lumen protein-retaining receptor 2 (KDELR2) 40.5
 LDTP00281  Golgi integral membrane protein 4 (GOLIM4) 39.7
 LDTP08904  Protein jagunal homolog 1 (JAGN1) 37.5
 LDTP15067  Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) 37.5
 LDTP05160  Nucleobindin-2 (NUCB2) 36.8
 LDTP12642  CYFIP-related Rac1 interactor B (CYRIB) 36.0
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 33.8
 LDTP09297  Large ribosomal subunit protein mL64 (GADD45GIP1) 33.6
 LDTP16080  Protein FAM114A2 (FAM114A2) 33.1
 LDTP03175  Galanin peptides (GAL) 32.7
 LDTP18569  PRELI domain containing protein 3B (PRELID3B) 30.5
 LDTP16192  Mitochondrial fission process protein 1 (MTFP1) 29.2
 LDTP08000  Dymeclin (DYM) 28.2
 LDTP12412  Reticulon-4 (RTN4) 28.1
 LDTP14939  Membralin (TMEM259) 27.5
 LDTP15095  Receptor expression-enhancing protein 3 (REEP3) 27.3
 LDTP11210  Transmembrane protein 43 (TMEM43) 27.3
 LDTP06948  Protein YIF1B (YIF1B) 26.4
 LDTP15110  Protein C3orf33 (C3orf33) 26.0
 LDTP01494  Protein YIF1A (YIF1A) 26.0
 LDTP13797  HIG1 domain family member 1A, mitochondrial (HIGD1A) 25.8
 LDTP16006  Optic atrophy 3 protein (OPA3) 24.6
 LDTP00986  Syntaxin-10 (STX10) 24.3
 LDTP11143  Centromere protein K (CENPK) 23.9
 LDTP14618  Protein PET100 homolog, mitochondrial (PET100) 23.9
 LDTP13086  Syntaxin-18 (STX18) 23.6
 LDTP08796  Protein SYS1 homolog (SYS1) 23.3
 LDTP11670  Mitochondrial fission factor (MFF) 22.8
 LDTP08364  Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) 22.5
 LDTP08606  Nurim (NRM) 22.5
 LDTP05868  Protein unc-119 homolog A (UNC119) 22.2
 LDTP16107  TBC1 domain family member 13 (TBC1D13) 22.0
 LDTP18272  Transmembrane protein 209 (TMEM209) 22.0
 LDTP04094  Large proline-rich protein BAG6 (BAG6) 21.9
 LDTP00859  Synaptogyrin-2 (SYNGR2) 21.3
 LDTP03926  Centrin-2 (CETN2) 21.0
 LDTP07274  MICOS complex subunit MIC13 (MICOS13) 20.5
 LDTP14716  ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) 20.3
 LDTP17580  FHF complex subunit HOOK-interacting protein 2B (FHIP2B) 20.3
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 19.3
 LDTP01359  Dynactin subunit 3 (DCTN3) 19.3
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 19.2
 LDTP02124  Keratin, type I cytoskeletal 18 (KRT18) 19.0
 LDTP18373  Thioredoxin-related transmembrane protein 4 (TMX4) 18.8
 LDTP00105  Protein unc-119 homolog B (UNC119B) 18.6
 LDTP19785  Transmembrane protein 35B (TMEM35B) 18.4
 LDTP07368  Tetratricopeptide repeat protein 19, mitochondrial (TTC19) 18.1
 LDTP19021  EF-hand calcium-binding domain-containing protein 14 (EFCAB14) 17.8
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 17.5
 LDTP09773  Protein FAM3C (FAM3C) 17.1
 LDTP17003  Matrix-remodeling-associated protein 7 (MXRA7) 17.0
 LDTP11113  Receptor expression-enhancing protein 2 (REEP2) 16.9
 LDTP15333  Trafficking protein particle complex subunit 5 (TRAPPC5) 16.9
 LDTP03352  Splicing factor U2AF 65 kDa subunit (U2AF2) 16.7
 LDTP05715  Vesicle transport protein SEC20 (BNIP1) 16.4
 LDTP01167  Reticulon-2 (RTN2) 16.3
 LDTP19963  TraB domain-containing protein (TRABD) 16.3
 LDTP13755  Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) 16.1
 LDTP06808  Vacuolar ATPase assembly integral membrane protein VMA21 (VMA21) 16.1
 LDTP01938  Apolipoprotein C-I (APOC1) 16.0
 LDTP12755  OCIA domain-containing protein 1 (OCIAD1) 16.0
 LDTP11883  Centromere protein H (CENPH) 15.6
 LDTP10184  HAUS augmin-like complex subunit 1 (HAUS1) 15.5
 LDTP08224  Protein LYRIC (MTDH) 15.5
 LDTP14259  Testis-expressed protein 264 (TEX264) 15.5
 LDTP19472  Protein NCBP2AS2 (NCBP2AS2) 15.3
 LDTP13125  Protein UXT (UXT) 15.3
 LDTP04703  Tumor protein D52 (TPD52) 15.2
 LDTP10924  Prohibitin-2 (PHB2) 15.0
 LDTP10442  Thioredoxin domain-containing protein 15 (TXNDC15) 15.0
 LDTP02297  Vimentin (VIM) 15.0
 LDTP11911  Golgi phosphoprotein 3 (GOLPH3) 14.9
 LDTP15741  Cytochrome c oxidase assembly protein COX14 (COX14) 14.8
 LDTP00729  Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) 14.8
 LDTP05530  Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) 14.8
 LDTP10567  Regulator of microtubule dynamics protein 2 (RMDN2) 14.8
 LDTP11326  FUN14 domain-containing protein 2 (FUNDC2) 14.5
 LDTP16322  Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) 14.2
 LDTP10116  Lipid droplet assembly factor 1 (LDAF1) 14.1
 LDTP19005  SLC35A4 upstream open reading frame protein (SLC35A4) 14.0
 LDTP01075  Protein CutA (CUTA) 13.7
 LDTP07891  Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) 13.5
 LDTP05277  Protein SET (SET) 13.5
 LDTP06097  Reticulocalbin-2 (RCN2) 13.3
 LDTP08509  FUN14 domain-containing protein 1 (FUNDC1) 13.2
 LDTP12982  Mitochondrial import receptor subunit TOM7 homolog (TOMM7) 13.1
 LDTP11978  HAUS augmin-like complex subunit 4 (HAUS4) 13.0
 LDTP00199  HCLS1-associated protein X-1 (HAX1) 13.0
 LDTP15434  ADP-ribosylation factor-like protein 6-interacting protein 6 (ARL6IP6) 12.8
 LDTP13967  Transmembrane emp24 domain-containing protein 5 (TMED5) 12.8
 LDTP06291  ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) 12.7
 LDTP15253  HEAT repeat-containing protein 3 (HEATR3) 12.6
 LDTP02180  Neurofilament light polypeptide (NEFL) 12.6
 LDTP16250  Translocon-associated protein subunit gamma (SSR3) 12.6
 LDTP08094  Wings apart-like protein homolog (WAPL) 12.6
 LDTP02181  Neurofilament medium polypeptide (NEFM) 12.6
 LDTP05960  Trophoblast glycoprotein (TPBG) 12.6
 LDTP15240  LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) 12.4
 LDTP15398  Protein FAM177A1 (FAM177A1) 12.1
 LDTP16285  Transducin beta-like protein 2 (TBL2) 12.1
 LDTP01466  HAUS augmin-like complex subunit 5 (HAUS5) 11.9
 LDTP04111  Small ribosomal subunit protein eS10 (RPS10) 11.9
 LDTP20361  Coiled-coil domain-containing protein 127 (CCDC127) 11.8
 LDTP10965  Nucleosome assembly protein 1-like 4 (NAP1L4) 11.8
 LDTP01652  Centrosomal protein 43 (CEP43) 11.6
 LDTP07508  Polyamine-modulated factor 1 (PMF1) 11.6

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587