Details of the Probe

General Information of Probe

Probe ID
LDPC0312
Probe Name
C055
Synonyms
Z4282859671
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 349.4
Lipid-water partition coefficient (xlogp) 2.4
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C17H21F2N5O
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-[2,2-difluoro-2-(4,5,6,7-tetrahydro-1H-indazol-3-yl)ethyl]propanamide
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)NCC(C2=NNC3=C2CCCC3)(F)F
InChI
InChI=1S/C17H21F2N5O/c1-2-3-9-16(23-24-16)10-8-14(25)20-11-17(18,19)15-12-6-4-5-7-13(12)21-22-15/h1H,3-11H2,(H,20,25)(H,21,22)
InChIKey
FZKVXDXDOKTZKM-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

146 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) LDTP12639 23.75  LDD1752 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 17.15  LDD1752 
Acylglycerol kinase, mitochondrial (AGK) LDTP06905 18.77  LDD1752 
Adenosine 5'-monophosphoramidase HINT3 (HINT3) LDTP12415 13.74  LDD1752 
Adenosine deaminase (ADA) LDTP01803 16.11  LDD1752 
Adenosine kinase (ADK) LDTP04689 45.57  LDD1752 
ADP-dependent glucokinase (ADPGK) LDTP11127 54.57  LDD1752 
ADP-ribosylation factor-like protein 1 (ARL1) LDTP03900 12.73  LDD1752 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 60.55  LDD1752 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 29.24  LDD1752 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 11.96  LDD1752 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 49.87  LDD1752 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 15.24  LDD1752 
Beta-1,4-galactosyltransferase 3 (B4GALT3) LDTP00994 13.27  LDD1752 
Branched-chain alpha-ketoacid dehydrogenase kinase (BCKDK) LDTP00462 20.11  LDD1752 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 19.29  LDD1752 
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CAMK2G) LDTP05920 11.88  LDD1752 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 29.24  LDD1752 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 24.93  LDD1752 
Catechol O-methyltransferase (COMT) LDTP03145 13.93  LDD1752 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 26.72  LDD1752 
Ceramide glucosyltransferase (UGCG) LDTP06617 19.29  LDD1752 
Ceramide synthase 1 (CERS1) LDTP03394 34.30  LDD1752 
Ceramide synthase 2 (CERS2) LDTP10329 35.75  LDD1752 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 18.13  LDD1752 
Choline/ethanolaminephosphotransferase 1 (CEPT1) LDTP14264 14.52  LDD1752 
Cyclin-dependent kinase 4 (CDK4) LDTP02589 13.18  LDD1752 
Cyclin-G-associated kinase (GAK) LDTP00497 11.79  LDD1752 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 63.12  LDD1752 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 51.27  LDD1752 
Cytochrome b5 type B (CYB5B) LDTP00697 50.91  LDD1752 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 21.86  LDD1752 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 31.12  LDD1752 
DCN1-like protein 3 (DCUN1D3) LDTP08538 31.12  LDD1752 
DCN1-like protein 4 (DCUN1D4) LDTP09799 17.51  LDD1752 
DCN1-like protein 5 (DCUN1D5) LDTP11199 13.83  LDD1752 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 17.88  LDD1752 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 12.73  LDD1752 
Delta(24)-sterol reductase (DHCR24) LDTP06375 13.93  LDD1752 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 12.04  LDD1752 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 15.89  LDD1752 
Dihydrofolate reductase (DHFR) LDTP01769 99.73  LDD1752 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 16.91  LDD1752 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 15.45  LDD1752 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 40.79  LDD1752 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 12.13  LDD1752 
E3 ubiquitin-protein ligase AMFR (AMFR) LDTP13491 13.27  LDD1752 
E3 ubiquitin-protein ligase RNF14 (RNF14) LDTP13154 12.55  LDD1752 
E3 ubiquitin-protein ligase TRIM13 (TRIM13) LDTP01065 26.17  LDD1752 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 27.67  LDD1752 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 12.21  LDD1752 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 27.10  LDD1752 
Epoxide hydrolase 1 (EPHX1) LDTP02175 20.97  LDD1752 
Ethanolamine kinase 1 (ETNK1) LDTP12197 13.27  LDD1752 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 32.67  LDD1752 
Geranylgeranyl transferase type-2 subunit beta (RABGGTB) LDTP04569 11.88  LDD1752 
Glutathione S-transferase A4 (GSTA4) LDTP00575 30.91  LDD1752 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 14.72  LDD1752 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 57.68  LDD1752 
Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) LDTP17305 12.21  LDD1752 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 47.50  LDD1752 
GPI ethanolamine phosphate transferase 2 (PIGG) LDTP06977 12.91  LDD1752 
GTP-binding protein SAR1a (SAR1A) LDTP12470 13.09  LDD1752 
Heme A synthase COX15 (COX15) LDTP07931 19.84  LDD1752 
Heme oxygenase 1 (HMOX1) LDTP02359 38.05  LDD1752 
Heme oxygenase 2 (HMOX2) LDTP03540 39.67  LDD1752 
Hexokinase-2 (HK2) LDTP04531 13.09  LDD1752 
Holocytochrome c-type synthase (HCCS) LDTP04581 15.35  LDD1752 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 28.84  LDD1752 
Inositol 1,4,5-trisphosphate receptor-interacting protein (ITPRIP) LDTP08532 23.92  LDD1752 
Isochorismatase domain-containing protein 1 (ISOC1) LDTP19851 12.21  LDD1752 
L-xylulose reductase (DCXR) LDTP08082 12.13  LDD1752 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 12.38  LDD1752 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 39.40  LDD1752 
Lon protease homolog 2, peroxisomal (LONP2) LDTP08323 12.04  LDD1752 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 22.78  LDD1752 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 14.52  LDD1752 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 14.42  LDD1752 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 13.00  LDD1752 
Lysosomal protective protein (CTSA) LDTP02505 31.12  LDD1752 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 20.25  LDD1752 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 56.49  LDD1752 
Mitochondrial intermediate peptidase (MIPEP) LDTP10981 15.14  LDD1752 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 99.73  LDD1752 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 40.50  LDD1752 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 13.55  LDD1752 
NADH dehydrogenase 1 alpha subcomplex subunit 3 (NDUFA3) LDTP01513 18.25  LDD1752 
NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1) LDTP01219 19.29  LDD1752 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 12.30  LDD1752 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 77.17  LDD1752 
NADH dehydrogenase 1 beta subcomplex subunit 5, mitochondrial (NDUFB5) LDTP00831 13.55  LDD1752 
NADH dehydrogenase 1 beta subcomplex subunit 6 (NDUFB6) LDTP01502 14.93  LDD1752 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 15.89  LDD1752 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 30.48  LDD1752 
NADPH--cytochrome P450 reductase (POR) LDTP02848 16.56  LDD1752 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 17.75  LDD1752 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 22.16  LDD1752 
Palmitoyltransferase ZDHHC13 (ZDHHC13) LDTP08455 22.94  LDD1752 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 20.39  LDD1752 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 12.73  LDD1752 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 32.90  LDD1752 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 13.74  LDD1752 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 12.30  LDD1752 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 17.88  LDD1752 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 17.39  LDD1752 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 14.32  LDD1752 
Presenilin-associated rhomboid-like protein, mitochondrial (PARL) LDTP11852 13.64  LDD1752 
Presequence protease, mitochondrial (PITRM1) LDTP07003 13.83  LDD1752 
Prolyl 3-hydroxylase 1 (P3H1) LDTP06750 24.93  LDD1752 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 12.30  LDD1752 
Prostaglandin reductase 3 (PTGR3) LDTP15422 13.55  LDD1752 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 24.93  LDD1752 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 26.91  LDD1752 
Protein O-GlcNAcase (OGA) LDTP00988 14.03  LDD1752 
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGNT2) LDTP09031 18.51  LDD1752 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 11.71  LDD1752 
Protein SCO2 homolog, mitochondrial (SCO2) LDTP00877 13.18  LDD1752 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 24.93  LDD1752 
RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 12.64  LDD1752 
Ras-related protein Rab-11B (RAB11B) LDTP06501 12.47  LDD1752 
Ras-related protein Rab-24 (RAB24) LDTP10020 20.82  LDD1752 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 26.17  LDD1752 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 14.52  LDD1752 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 12.73  LDD1752 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 26.91  LDD1752 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 49.52  LDD1752 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 12.91  LDD1752 
Sphingosine kinase 2 (SPHK2) LDTP12490 13.18  LDD1752 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 17.75  LDD1752 
Squalene monooxygenase (SQLE) LDTP06142 11.63  LDD1752 
Squalene synthase (FDFT1) LDTP03842 56.49  LDD1752 
Thioredoxin-like protein 1 (TXNL1) LDTP00758 13.00  LDD1752 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 13.55  LDD1752 
TLC domain-containing protein 1 (TLCD1) LDTP10182 16.68  LDD1752 
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (TRMT61A) LDTP10320 11.71  LDD1752 
UbiA prenyltransferase domain-containing protein 1 (UBIAD1) LDTP14189 12.82  LDD1752 
Ubiquinone biosynthesis O-methyltransferase, mitochondrial (COQ3) LDTP12908 12.38  LDD1752 
Ubiquitin carboxyl-terminal hydrolase 11 (USP11) LDTP04456 13.27  LDD1752 
Ubiquitin carboxyl-terminal hydrolase 28 (USP28) LDTP10785 15.45  LDD1752 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 14.83  LDD1752 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (HACD2) LDTP07756 13.36  LDD1752 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 13.00  LDD1752 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 14.52  LDD1752 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 12.13  LDD1752 
Xaa-Pro aminopeptidase 3 (XPNPEP3) LDTP12420 17.03  LDD1752 
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP1) LDTP12960 16.68  LDD1752 
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⏷ Show the Full List of 146 Enzyme
112 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 17.03  LDD1752 
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 11.63  LDD1752 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 19.97  LDD1752 
Amino acid transporter heavy chain SLC3A2 (SLC3A2) LDTP02256 19.29  LDD1752 
AP-4 complex subunit mu-1 (AP4M1) LDTP00208 16.56  LDD1752 
ATP synthase subunit a (MT-ATP6) LDTP01804 73.01  LDD1752 
ATP synthase subunit e, mitochondrial (ATP5ME) LDTP14717 14.83  LDD1752 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 78.25  LDD1752 
BRI3-binding protein (BRI3BP) LDTP15648 41.64  LDD1752 
Cell division cycle protein 20 homolog (CDC20) LDTP05662 13.64  LDD1752 
Ceroid-lipofuscinosis neuronal protein 6 (CLN6) LDTP12738 13.27  LDD1752 
Coiled-coil domain-containing protein 22 (CCDC22) LDTP01056 13.55  LDD1752 
Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) LDTP08469 13.74  LDD1752 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 28.64  LDD1752 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 19.97  LDD1752 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 99.73  LDD1752 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 13.36  LDD1752 
Derlin-1 (DERL1) LDTP11245 39.40  LDD1752 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 12.04  LDD1752 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 30.48  LDD1752 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 29.65  LDD1752 
Essential MCU regulator, mitochondrial (SMDT1) LDTP11927 79.89  LDD1752 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 14.32  LDD1752 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 17.75  LDD1752 
Importin-4 (IPO4) LDTP09515 14.03  LDD1752 
Intraflagellar transport protein 56 (IFT56) LDTP00010 11.71  LDD1752 
Large neutral amino acids transporter small subunit 1 (SLC7A5) LDTP05305 45.89  LDD1752 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 16.00  LDD1752 
Lysosomal cobalamin transport escort protein LMBD1 (LMBRD1) LDTP12636 14.32  LDD1752 
Lysosomal-associated transmembrane protein 4A (LAPTM4A) LDTP06275 15.89  LDD1752 
Lysosome membrane protein 2 (SCARB2) LDTP06034 15.24  LDD1752 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 22.01  LDD1752 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 14.32  LDD1752 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 14.93  LDD1752 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 29.24  LDD1752 
Metaxin-1 (MTX1) LDTP05900 48.17  LDD1752 
MICOS complex subunit MIC26 (APOO) LDTP11250 14.93  LDD1752 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 13.74  LDD1752 
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) LDTP07439 12.21  LDD1752 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 13.93  LDD1752 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 19.70  LDD1752 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 28.84  LDD1752 
Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42) LDTP08279 22.32  LDD1752 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 35.26  LDD1752 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 33.59  LDD1752 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 99.73  LDD1752 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 99.73  LDD1752 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 24.76  LDD1752 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 15.78  LDD1752 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 32.22  LDD1752 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 13.93  LDD1752 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 19.84  LDD1752 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 27.67  LDD1752 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 12.73  LDD1752 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 18.13  LDD1752 
Mpv17-like protein 2 (MPV17L2) LDTP14952 18.77  LDD1752 
Multiple coagulation factor deficiency protein 2 (MCFD2) LDTP09278 19.03  LDD1752 
Nucleoporin NDC1 (NDC1) LDTP11213 21.56  LDD1752 
Nucleoporin Nup37 (NUP37) LDTP09203 11.71  LDD1752 
Nucleoporin Nup43 (NUP43) LDTP09202 11.96  LDD1752 
Pannexin-1 (PANX1) LDTP10754 11.71  LDD1752 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 14.03  LDD1752 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 17.03  LDD1752 
Phosphatidylinositol transfer protein alpha isoform (PITPNA) LDTP05236 12.13  LDD1752 
PRA1 family protein 2 (PRAF2) LDTP01060 15.45  LDD1752 
Prosaposin (PSAP) LDTP02215 12.47  LDD1752 
Protein ARV1 (ARV1) LDTP11812 14.62  LDD1752 
Protein FAM8A1 (FAM8A1) LDTP16190 16.80  LDD1752 
Protein GPR107 (GPR107) LDTP07236 35.26  LDD1752 
Protein GPR108 (GPR108) LDTP12383 29.86  LDD1752 
Protein SEC13 homolog (SEC13) LDTP04707 19.56  LDD1752 
Protein wntless homolog (WLS) LDTP07156 14.52  LDD1752 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 15.45  LDD1752 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 20.97  LDD1752 
Renin receptor (ATP6AP2) LDTP01309 12.04  LDD1752 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 16.68  LDD1752 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 12.38  LDD1752 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 14.83  LDD1752 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 39.12  LDD1752 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 17.88  LDD1752 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 15.89  LDD1752 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 19.43  LDD1752 
Sorting nexin-6 (SNX6) LDTP13661 12.73  LDD1752 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 24.59  LDD1752 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 14.22  LDD1752 
Surfeit locus protein 4 (SURF4) LDTP00592 15.24  LDD1752 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 27.28  LDD1752 
Tetraspanin-3 (TSPAN3) LDTP16813 25.46  LDD1752 
Thioredoxin-related transmembrane protein 2 (TMX2) LDTP13943 11.96  LDD1752 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 33.13  LDD1752 
Translocator protein (TSPO) LDTP03546 39.40  LDD1752 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 46.53  LDD1752 
Translocon-associated protein subunit beta (SSR2) LDTP14682 16.56  LDD1752 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 24.08  LDD1752 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 11.96  LDD1752 
Transmembrane protein 126A (TMEM126A) LDTP15948 64.00  LDD1752 
Transmembrane protein 160 (TMEM160) LDTP20002 66.72  LDD1752 
Transmembrane protein 199 (TMEM199) LDTP08881 46.85  LDD1752 
Transmembrane protein 205 (TMEM205) LDTP07667 13.00  LDD1752 
Transmembrane protein 230 (TMEM230) LDTP10065 24.93  LDD1752 
Transmembrane protein 245 (TMEM245) LDTP15979 11.96  LDD1752 
Transmembrane protein 59 (TMEM59) LDTP11406 15.24  LDD1752 
Transmembrane protein 87A (TMEM87A) LDTP15481 20.39  LDD1752 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 20.39  LDD1752 
V-type proton ATPase subunit B, brain isoform (ATP6V1B2) LDTP03104 13.27  LDD1752 
Vacuole membrane protein 1 (VMP1) LDTP10343 14.42  LDD1752 
Vang-like protein 1 (VANGL1) LDTP09288 15.35  LDD1752 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 83.29  LDD1752 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 64.00  LDD1752 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 17.88  LDD1752 
Zinc transporter 7 (SLC30A7) LDTP09180 27.28  LDD1752 
Zinc transporter ZIP11 (SLC39A11) LDTP17682 29.65  LDD1752 
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⏷ Show the Full List of 112 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 19.97  LDD1752 
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1 GPCR Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Membrane progestin receptor alpha (PAQR7) LDTP15303 28.64  LDD1752 
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3 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 15.56  LDD1752 
HLA class I histocompatibility antigen, alpha chain F (HLA-F) LDTP03538 26.72  LDD1752 
Neuroplastin (NPTN) LDTP14205 18.13  LDD1752 
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120 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 12.73  LDD1752 
ADP-ribosylation factor-like protein 6-interacting protein 6 (ARL6IP6) LDTP15434 12.82  LDD1752 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 22.47  LDD1752 
Apolipoprotein C-I (APOC1) LDTP01938 16.00  LDD1752 
Apolipoprotein L2 (APOL2) LDTP11076 43.71  LDD1752 
ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) LDTP14716 20.25  LDD1752 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 16.11  LDD1752 
Centrin-2 (CETN2) LDTP03926 20.97  LDD1752 
Centromere protein H (CENPH) LDTP11883 15.56  LDD1752 
Centromere protein K (CENPK) LDTP11143 23.92  LDD1752 
Centrosomal protein 43 (CEP43) LDTP01652 11.63  LDD1752 
Clustered mitochondria protein homolog (CLUH) LDTP14486 19.29  LDD1752 
Coiled-coil domain-containing protein 127 (CCDC127) LDTP20361 11.79  LDD1752 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 36.00  LDD1752 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 67.65  LDD1752 
Cytochrome c oxidase assembly protein COX14 (COX14) LDTP15741 14.83  LDD1752 
Dymeclin (DYM) LDTP08000 28.25  LDD1752 
Dynactin subunit 3 (DCTN3) LDTP01359 19.29  LDD1752 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 17.75  LDD1752 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 99.73  LDD1752 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 33.82  LDD1752 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 40.50  LDD1752 
FHF complex subunit HOOK-interacting protein 2B (FHIP2B) LDTP17580 20.25  LDD1752 
FUN14 domain-containing protein 1 (FUNDC1) LDTP08509 13.18  LDD1752 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 14.52  LDD1752 
Galanin peptides (GAL) LDTP03175 32.67  LDD1752 
Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) LDTP00729 14.83  LDD1752 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 39.67  LDD1752 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 14.93  LDD1752 
HAUS augmin-like complex subunit 1 (HAUS1) LDTP10184 15.45  LDD1752 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 13.00  LDD1752 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 11.88  LDD1752 
HCLS1-associated protein X-1 (HAX1) LDTP00199 13.00  LDD1752 
HEAT repeat-containing protein 3 (HEATR3) LDTP15253 12.64  LDD1752 
HIG1 domain family member 1A, mitochondrial (HIGD1A) LDTP13797 25.81  LDD1752 
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) LDTP05530 14.83  LDD1752 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 13.55  LDD1752 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 19.03  LDD1752 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 17.51  LDD1752 
Large proline-rich protein BAG6 (BAG6) LDTP04094 21.86  LDD1752 
Large ribosomal subunit protein mL64 (GADD45GIP1) LDTP09297 33.59  LDD1752 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 70.03  LDD1752 
Lipid droplet assembly factor 1 (LDAF1) LDTP10116 14.12  LDD1752 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 12.38  LDD1752 
Matrix-remodeling-associated protein 7 (MXRA7) LDTP17003 17.03  LDD1752 
Membralin (TMEM259) LDTP14939 27.47  LDD1752 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 20.53  LDD1752 
Mitochondrial fission factor (MFF) LDTP11670 22.78  LDD1752 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 29.24  LDD1752 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 14.22  LDD1752 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD1752 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 99.73  LDD1752 
Mitochondrial import receptor subunit TOM7 homolog (TOMM7) LDTP12982 13.09  LDD1752 
Neurofilament light polypeptide (NEFL) LDTP02180 12.64  LDD1752 
Neurofilament medium polypeptide (NEFM) LDTP02181 12.55  LDD1752 
Nucleobindin-1 (NUCB1) LDTP05375 49.87  LDD1752 
Nucleobindin-2 (NUCB2) LDTP05160 36.76  LDD1752 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 11.79  LDD1752 
Nurim (NRM) LDTP08606 22.47  LDD1752 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 16.00  LDD1752 
Optic atrophy 3 protein (OPA3) LDTP16006 24.59  LDD1752 
p53 and DNA damage-regulated protein 1 (PDRG1) LDTP16099 79.89  LDD1752 
Polyamine-modulated factor 1 (PMF1) LDTP07508 11.63  LDD1752 
PRELI domain containing protein 3B (PRELID3B) LDTP18569 30.48  LDD1752 
Prohibitin-2 (PHB2) LDTP10924 15.03  LDD1752 
Protein C3orf33 (C3orf33) LDTP15110 25.99  LDD1752 
Protein CEBPZOS (CEBPZOS) LDTP18883 54.19  LDD1752 
Protein CutA (CUTA) LDTP01075 13.74  LDD1752 
Protein FAM114A2 (FAM114A2) LDTP16080 33.13  LDD1752 
Protein FAM162A (FAM162A) LDTP10056 45.25  LDD1752 
Protein FAM177A1 (FAM177A1) LDTP15398 12.13  LDD1752 
Protein FAM3C (FAM3C) LDTP09773 17.15  LDD1752 
Protein jagunal homolog 1 (JAGN1) LDTP08904 37.53  LDD1752 
Protein LYRIC (MTDH) LDTP08224 15.45  LDD1752 
Protein NCBP2AS2 (NCBP2AS2) LDTP19472 15.35  LDD1752 
Protein PET100 homolog, mitochondrial (PET100) LDTP14618 23.92  LDD1752 
Protein SET (SET) LDTP05277 13.45  LDD1752 
Protein SYS1 homolog (SYS1) LDTP08796 23.26  LDD1752 
Protein unc-119 homolog A (UNC119) LDTP05868 22.16  LDD1752 
Protein unc-119 homolog B (UNC119B) LDTP00105 18.64  LDD1752 
Protein UXT (UXT) LDTP13125 15.35  LDD1752 
Protein YIF1A (YIF1A) LDTP01494 25.99  LDD1752 
Protein YIF1B (YIF1B) LDTP06948 26.35  LDD1752 
Receptor expression-enhancing protein 2 (REEP2) LDTP11113 16.91  LDD1752 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 27.28  LDD1752 
Regulator of microtubule dynamics protein 2 (RMDN2) LDTP10567 14.83  LDD1752 
Reticulocalbin-2 (RCN2) LDTP06097 13.27  LDD1752 
Reticulon-2 (RTN2) LDTP01167 16.34  LDD1752 
Reticulon-3 (RTN3) LDTP01522 47.84  LDD1752 
Reticulon-4 (RTN4) LDTP12412 28.05  LDD1752 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 19.16  LDD1752 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 14.03  LDD1752 
Small integral membrane protein 12 (SMIM12) LDTP19859 76.64  LDD1752 
Small ribosomal subunit protein eS10 (RPS10) LDTP04111 11.88  LDD1752 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 16.68  LDD1752 
Synaptogyrin-2 (SYNGR2) LDTP00859 21.26  LDD1752 
Syntaxin-10 (STX10) LDTP00986 24.25  LDD1752 
Syntaxin-18 (STX18) LDTP13086 23.59  LDD1752 
TBC1 domain family member 13 (TBC1D13) LDTP16107 22.01  LDD1752 
Testis-expressed protein 264 (TEX264) LDTP14259 15.45  LDD1752 
Tetraspanin-6 (TSPAN6) LDTP14458 41.36  LDD1752 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 18.13  LDD1752 
Thioredoxin domain-containing protein 15 (TXNDC15) LDTP10442 15.03  LDD1752 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 18.77  LDD1752 
TraB domain-containing protein (TRABD) LDTP19963 16.34  LDD1752 
Trafficking protein particle complex subunit 5 (TRAPPC5) LDTP15333 16.91  LDD1752 
Transducin beta-like protein 2 (TBL2) LDTP16285 12.13  LDD1752 
Translocon-associated protein subunit gamma (SSR3) LDTP16250 12.64  LDD1752 
Transmembrane emp24 domain-containing protein 5 (TMED5) LDTP13967 12.82  LDD1752 
Transmembrane protein 209 (TMEM209) LDTP18272 22.01  LDD1752 
Transmembrane protein 35B (TMEM35B) LDTP19785 18.38  LDD1752 
Transmembrane protein 43 (TMEM43) LDTP11210 27.28  LDD1752 
Trophoblast glycoprotein (TPBG) LDTP05960 12.55  LDD1752 
Tumor protein D52 (TPD52) LDTP04703 15.24  LDD1752 
Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) LDTP15634 92.41  LDD1752 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 37.53  LDD1752 
Vacuolar ATPase assembly integral membrane protein VMA21 (VMA21) LDTP06808 16.11  LDD1752 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 16.45  LDD1752 
Vimentin (VIM) LDTP02297 15.03  LDD1752 
Wings apart-like protein homolog (WAPL) LDTP08094 12.64  LDD1752 
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⏷ Show the Full List of 120 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1752 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587