Details of the Probe

General Information of Probe

Probe ID
LDPC0430
Probe Name
C194
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 343.402
Lipid-water partition coefficient (xlogp) 2.9992
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C19H22FN3O2
Canonical SMILES
[H]C#CC([H])([H])C([H])([H])C1(C([H])([H])C([H])([H])N([H])C(=O)C2(C([H])([H])c3c([H])c([H])c(F)c([H])c3[H])OC([H])([H])C([H])([H])C2([H])[H])N=N1
InChI
InChI=1S/C19H22FN3O2/c1-2-3-10-19(22-23-19)11-12-21-17(24)18(9-4-13-25-18)14-15-5-7-16(20)8-6-15/h1,5-8H,3-4,9-14H2,(H,21,24)/t18-/m0/s1
InChIKey
OUSLFJDGNKGYNW-SFHVURJKSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

190 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 17.03  LDD1870 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 17.03  LDD1870 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 9.00  LDD1870 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 9.00  LDD1870 
7-dehydrocholesterol reductase (DHCR7) LDTP13131 8.51  LDD1870 
7-dehydrocholesterol reductase (DHCR7) LDTP13131 8.51  LDD1870 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 18.64  LDD1870 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 18.64  LDD1870 
Acid ceramidase (ASAH1) LDTP05905 17.39  LDD1870 
Acid ceramidase (ASAH1) LDTP05905 17.39  LDD1870 
ADP-dependent glucokinase (ADPGK) LDTP11127 12.91  LDD1870 
ADP-dependent glucokinase (ADPGK) LDTP11127 12.91  LDD1870 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 13.45  LDD1870 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 13.45  LDD1870 
Alpha-galactosidase A (GLA) LDTP02141 9.58  LDD1870 
Alpha-galactosidase A (GLA) LDTP02141 9.58  LDD1870 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 12.55  LDD1870 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 12.55  LDD1870 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 10.48  LDD1870 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 10.48  LDD1870 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 8.46  LDD1870 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 8.46  LDD1870 
Beta-galactosidase (GLB1) LDTP02837 16.34  LDD1870 
Beta-galactosidase (GLB1) LDTP02837 16.34  LDD1870 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 9.92  LDD1870 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 9.92  LDD1870 
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPSS1) LDTP00717 10.85  LDD1870 
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPSS1) LDTP00717 10.85  LDD1870 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 11.31  LDD1870 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 11.31  LDD1870 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 22.16  LDD1870 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 22.16  LDD1870 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 12.47  LDD1870 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 12.47  LDD1870 
Catechol O-methyltransferase (COMT) LDTP03145 9.06  LDD1870 
Catechol O-methyltransferase (COMT) LDTP03145 9.06  LDD1870 
Cathepsin B (CTSB) LDTP02223 13.55  LDD1870 
Cathepsin B (CTSB) LDTP02223 13.55  LDD1870 
Ceramide glucosyltransferase (UGCG) LDTP06617 23.92  LDD1870 
Ceramide glucosyltransferase (UGCG) LDTP06617 23.92  LDD1870 
Ceramide synthase 2 (CERS2) LDTP10329 21.56  LDD1870 
Ceramide synthase 2 (CERS2) LDTP10329 21.56  LDD1870 
Choline kinase alpha (CHKA) LDTP03787 49.52  LDD1870 
Choline kinase alpha (CHKA) LDTP03787 49.52  LDD1870 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 25.28  LDD1870 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 25.28  LDD1870 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 32.00  LDD1870 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 32.00  LDD1870 
Cytochrome b5 type B (CYB5B) LDTP00697 19.16  LDD1870 
Cytochrome b5 type B (CYB5B) LDTP00697 19.16  LDD1870 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 15.03  LDD1870 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 15.03  LDD1870 
DCN1-like protein 4 (DCUN1D4) LDTP09799 8.69  LDD1870 
DCN1-like protein 4 (DCUN1D4) LDTP09799 8.69  LDD1870 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 23.10  LDD1870 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 23.10  LDD1870 
Delta(24)-sterol reductase (DHCR24) LDTP06375 14.62  LDD1870 
Delta(24)-sterol reductase (DHCR24) LDTP06375 14.62  LDD1870 
Deoxyhypusine hydroxylase (DOHH) LDTP11225 9.32  LDD1870 
Deoxyhypusine hydroxylase (DOHH) LDTP11225 9.32  LDD1870 
Dihydrofolate reductase (DHFR) LDTP01769 30.91  LDD1870 
Dihydrofolate reductase (DHFR) LDTP01769 30.91  LDD1870 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 9.45  LDD1870 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 9.45  LDD1870 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 13.27  LDD1870 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 13.27  LDD1870 
Endoplasmic reticulum metallopeptidase 1 (ERMP1) LDTP08017 12.21  LDD1870 
Endoplasmic reticulum metallopeptidase 1 (ERMP1) LDTP08017 12.21  LDD1870 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 12.55  LDD1870 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 12.55  LDD1870 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 13.93  LDD1870 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 13.93  LDD1870 
Epoxide hydrolase 1 (EPHX1) LDTP02175 31.78  LDD1870 
Epoxide hydrolase 1 (EPHX1) LDTP02175 31.78  LDD1870 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 13.36  LDD1870 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 13.36  LDD1870 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 9.78  LDD1870 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 9.78  LDD1870 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 11.47  LDD1870 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 11.47  LDD1870 
Heme oxygenase 1 (HMOX1) LDTP02359 15.78  LDD1870 
Heme oxygenase 1 (HMOX1) LDTP02359 15.78  LDD1870 
Heme oxygenase 2 (HMOX2) LDTP03540 20.39  LDD1870 
Heme oxygenase 2 (HMOX2) LDTP03540 20.39  LDD1870 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 9.92  LDD1870 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 9.92  LDD1870 
Kinesin-like protein KIF23 (KIF23) LDTP05344 11.39  LDD1870 
Kinesin-like protein KIF23 (KIF23) LDTP05344 11.39  LDD1870 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 11.39  LDD1870 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 11.39  LDD1870 
Legumain (LGMN) LDTP10888 10.41  LDD1870 
Legumain (LGMN) LDTP10888 10.41  LDD1870 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 23.26  LDD1870 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 23.26  LDD1870 
Long-chain-fatty-acid--CoA ligase 1 (ACSL1) LDTP03662 16.68  LDD1870 
Long-chain-fatty-acid--CoA ligase 1 (ACSL1) LDTP03662 16.68  LDD1870 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 14.62  LDD1870 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 14.62  LDD1870 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 26.17  LDD1870 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 26.17  LDD1870 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 9.00  LDD1870 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 9.00  LDD1870 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 18.77  LDD1870 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 18.77  LDD1870 
Lysosomal acid phosphatase (ACP2) LDTP02539 9.45  LDD1870 
Lysosomal acid phosphatase (ACP2) LDTP02539 9.45  LDD1870 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 10.78  LDD1870 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 10.78  LDD1870 
Lysosomal protective protein (CTSA) LDTP02505 24.08  LDD1870 
Lysosomal protective protein (CTSA) LDTP02505 24.08  LDD1870 
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCAT) LDTP08512 54.95  LDD1870 
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCAT) LDTP08512 54.95  LDD1870 
Mannose-1-phosphate guanyltransferase beta (GMPPB) LDTP14141 8.75  LDD1870 
Mannose-1-phosphate guanyltransferase beta (GMPPB) LDTP14141 8.75  LDD1870 
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial (ALDH6A1) LDTP05346 12.55  LDD1870 
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial (ALDH6A1) LDTP05346 12.55  LDD1870 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 12.21  LDD1870 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 12.21  LDD1870 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 13.36  LDD1870 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 13.36  LDD1870 
NAD-capped RNA hydrolase NUDT12 (NUDT12) LDTP11081 9.99  LDD1870 
NAD-capped RNA hydrolase NUDT12 (NUDT12) LDTP11081 9.99  LDD1870 
NADH dehydrogenase 1 alpha subcomplex subunit 3 (NDUFA3) LDTP01513 8.82  LDD1870 
NADH dehydrogenase 1 alpha subcomplex subunit 3 (NDUFA3) LDTP01513 8.82  LDD1870 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 28.64  LDD1870 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 28.64  LDD1870 
NADPH--cytochrome P450 reductase (POR) LDTP02848 9.58  LDD1870 
NADPH--cytochrome P450 reductase (POR) LDTP02848 9.58  LDD1870 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 30.06  LDD1870 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 30.06  LDD1870 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 17.75  LDD1870 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 17.75  LDD1870 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 27.28  LDD1870 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 27.28  LDD1870 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 9.58  LDD1870 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 9.58  LDD1870 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 56.10  LDD1870 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 56.10  LDD1870 
Phospholipase A-2-activating protein (PLAA) LDTP13814 9.00  LDD1870 
Phospholipase A-2-activating protein (PLAA) LDTP13814 9.00  LDD1870 
Phospholipase A2 group XV (PLA2G15) LDTP09088 9.71  LDD1870 
Phospholipase A2 group XV (PLA2G15) LDTP09088 9.71  LDD1870 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 20.25  LDD1870 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 20.25  LDD1870 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 9.45  LDD1870 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 9.45  LDD1870 
Prolyl endopeptidase-like (PREPL) LDTP06849 8.51  LDD1870 
Prolyl endopeptidase-like (PREPL) LDTP06849 8.51  LDD1870 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 31.12  LDD1870 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 31.12  LDD1870 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 11.24  LDD1870 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 11.24  LDD1870 
Protein O-GlcNAcase (OGA) LDTP00988 11.00  LDD1870 
Protein O-GlcNAcase (OGA) LDTP00988 11.00  LDD1870 
Protein O-mannosyl-transferase TMTC3 (TMTC3) LDTP07868 14.83  LDD1870 
Protein O-mannosyl-transferase TMTC3 (TMTC3) LDTP07868 14.83  LDD1870 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 18.25  LDD1870 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 18.25  LDD1870 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 17.15  LDD1870 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 17.15  LDD1870 
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) LDTP02549 19.29  LDD1870 
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) LDTP02549 19.29  LDD1870 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 16.80  LDD1870 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 16.80  LDD1870 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 9.85  LDD1870 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 9.85  LDD1870 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PPP2R1B) LDTP03523 9.06  LDD1870 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PPP2R1B) LDTP03523 9.06  LDD1870 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 18.38  LDD1870 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 18.38  LDD1870 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 11.96  LDD1870 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 11.96  LDD1870 
Squalene synthase (FDFT1) LDTP03842 18.25  LDD1870 
Squalene synthase (FDFT1) LDTP03842 18.25  LDD1870 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 13.83  LDD1870 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 13.83  LDD1870 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 9.99  LDD1870 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 9.99  LDD1870 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 9.19  LDD1870 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 9.19  LDD1870 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 11.63  LDD1870 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 11.63  LDD1870 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 9.00  LDD1870 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 9.00  LDD1870 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 28.64  LDD1870 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 28.64  LDD1870 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 8.94  LDD1870 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 8.94  LDD1870 
X-ray repair cross-complementing protein 6 (XRCC6) LDTP02640 10.48  LDD1870 
X-ray repair cross-complementing protein 6 (XRCC6) LDTP02640 10.48  LDD1870 
------------------------------------------------------------------------------------
⏷ Show the Full List of 190 Enzyme
138 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 12.55  LDD1870 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 12.55  LDD1870 
Amino acid transporter heavy chain SLC3A2 (SLC3A2) LDTP02256 9.71  LDD1870 
Amino acid transporter heavy chain SLC3A2 (SLC3A2) LDTP02256 9.71  LDD1870 
Amyloid-beta precursor protein (APP) LDTP02071 10.06  LDD1870 
Amyloid-beta precursor protein (APP) LDTP02071 10.06  LDD1870 
Annexin A1 (ANXA1) LDTP02010 12.38  LDD1870 
Annexin A1 (ANXA1) LDTP02010 12.38  LDD1870 
ATP synthase subunit a (MT-ATP6) LDTP01804 19.03  LDD1870 
ATP synthase subunit a (MT-ATP6) LDTP01804 19.03  LDD1870 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 23.75  LDD1870 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 23.75  LDD1870 
BOS complex subunit NCLN (NCLN) LDTP10036 11.79  LDD1870 
BOS complex subunit NCLN (NCLN) LDTP10036 11.79  LDD1870 
Cell division cycle protein 20 homolog (CDC20) LDTP05662 16.56  LDD1870 
Cell division cycle protein 20 homolog (CDC20) LDTP05662 16.56  LDD1870 
Ceramide transfer protein (CERT1) LDTP14140 15.78  LDD1870 
Ceramide transfer protein (CERT1) LDTP14140 15.78  LDD1870 
CMP-sialic acid transporter (SLC35A1) LDTP05116 22.94  LDD1870 
CMP-sialic acid transporter (SLC35A1) LDTP05116 22.94  LDD1870 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 8.51  LDD1870 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 8.51  LDD1870 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 8.88  LDD1870 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 8.88  LDD1870 
Derlin-1 (DERL1) LDTP11245 10.06  LDD1870 
Derlin-1 (DERL1) LDTP11245 10.06  LDD1870 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 22.78  LDD1870 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 22.78  LDD1870 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 14.03  LDD1870 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 14.03  LDD1870 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 10.63  LDD1870 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 10.63  LDD1870 
Integral membrane protein 2C (ITM2C) LDTP12451 9.19  LDD1870 
Integral membrane protein 2C (ITM2C) LDTP12451 9.19  LDD1870 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 10.48  LDD1870 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 10.48  LDD1870 
Lysosome membrane protein 2 (SCARB2) LDTP06034 18.00  LDD1870 
Lysosome membrane protein 2 (SCARB2) LDTP06034 18.00  LDD1870 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 12.04  LDD1870 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 12.04  LDD1870 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 12.13  LDD1870 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 12.13  LDD1870 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 18.00  LDD1870 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 18.00  LDD1870 
Metaxin-1 (MTX1) LDTP05900 26.54  LDD1870 
Metaxin-1 (MTX1) LDTP05900 26.54  LDD1870 
MICOS complex subunit MIC26 (APOO) LDTP11250 10.41  LDD1870 
MICOS complex subunit MIC26 (APOO) LDTP11250 10.41  LDD1870 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 21.11  LDD1870 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 21.11  LDD1870 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 10.13  LDD1870 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 10.13  LDD1870 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 69.55  LDD1870 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 69.55  LDD1870 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 36.76  LDD1870 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 36.76  LDD1870 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 12.91  LDD1870 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 12.91  LDD1870 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 13.55  LDD1870 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 13.55  LDD1870 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 8.75  LDD1870 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 8.75  LDD1870 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 8.51  LDD1870 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 8.51  LDD1870 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 14.72  LDD1870 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 14.72  LDD1870 
Mpv17-like protein 2 (MPV17L2) LDTP14952 24.42  LDD1870 
Mpv17-like protein 2 (MPV17L2) LDTP14952 24.42  LDD1870 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 12.30  LDD1870 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 12.30  LDD1870 
Nucleoporin NDC1 (NDC1) LDTP11213 9.25  LDD1870 
Nucleoporin NDC1 (NDC1) LDTP11213 9.25  LDD1870 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 9.92  LDD1870 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 9.92  LDD1870 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 18.64  LDD1870 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 18.64  LDD1870 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 9.99  LDD1870 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 9.99  LDD1870 
PRA1 family protein 2 (PRAF2) LDTP01060 10.85  LDD1870 
PRA1 family protein 2 (PRAF2) LDTP01060 10.85  LDD1870 
Prosaposin (PSAP) LDTP02215 22.32  LDD1870 
Prosaposin (PSAP) LDTP02215 22.32  LDD1870 
Protein ARV1 (ARV1) LDTP11812 16.00  LDD1870 
Protein ARV1 (ARV1) LDTP11812 16.00  LDD1870 
Protein FAM8A1 (FAM8A1) LDTP16190 13.55  LDD1870 
Protein FAM8A1 (FAM8A1) LDTP16190 13.55  LDD1870 
Protein GPR107 (GPR107) LDTP07236 14.93  LDD1870 
Protein GPR107 (GPR107) LDTP07236 14.93  LDD1870 
Protein GPR108 (GPR108) LDTP12383 18.38  LDD1870 
Protein GPR108 (GPR108) LDTP12383 18.38  LDD1870 
Protein tweety homolog 3 (TTYH3) LDTP11615 21.11  LDD1870 
Protein tweety homolog 3 (TTYH3) LDTP11615 21.11  LDD1870 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 9.78  LDD1870 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 9.78  LDD1870 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 13.45  LDD1870 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 13.45  LDD1870 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 14.72  LDD1870 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 14.72  LDD1870 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 11.31  LDD1870 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 11.31  LDD1870 
Sideroflexin-4 (SFXN4) LDTP07531 8.88  LDD1870 
Sideroflexin-4 (SFXN4) LDTP07531 8.88  LDD1870 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 20.82  LDD1870 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 20.82  LDD1870 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 32.90  LDD1870 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 32.90  LDD1870 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 14.62  LDD1870 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 14.62  LDD1870 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 11.31  LDD1870 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 11.31  LDD1870 
Solute carrier family 35 member F1 (SLC35F1) LDTP15000 8.51  LDD1870 
Solute carrier family 35 member F1 (SLC35F1) LDTP15000 8.51  LDD1870 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 15.67  LDD1870 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 15.67  LDD1870 
Stomatin (STOM) LDTP03380 13.83  LDD1870 
Stomatin (STOM) LDTP03380 13.83  LDD1870 
Tetraspanin-3 (TSPAN3) LDTP16813 23.10  LDD1870 
Tetraspanin-3 (TSPAN3) LDTP16813 23.10  LDD1870 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 27.67  LDD1870 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 27.67  LDD1870 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 25.11  LDD1870 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 25.11  LDD1870 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 11.88  LDD1870 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 11.88  LDD1870 
Transmembrane protein 126A (TMEM126A) LDTP15948 27.28  LDD1870 
Transmembrane protein 126A (TMEM126A) LDTP15948 27.28  LDD1870 
Transmembrane protein 160 (TMEM160) LDTP20002 21.26  LDD1870 
Transmembrane protein 160 (TMEM160) LDTP20002 21.26  LDD1870 
Transmembrane protein 199 (TMEM199) LDTP08881 22.63  LDD1870 
Transmembrane protein 199 (TMEM199) LDTP08881 22.63  LDD1870 
Transmembrane protein 230 (TMEM230) LDTP10065 12.47  LDD1870 
Transmembrane protein 230 (TMEM230) LDTP10065 12.47  LDD1870 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 21.71  LDD1870 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 21.71  LDD1870 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 24.93  LDD1870 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 24.93  LDD1870 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 8.94  LDD1870 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 8.94  LDD1870 
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⏷ Show the Full List of 138 Transporter and channel
2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 8.51  LDD1870 
Basigin (BSG) LDTP03772 8.51  LDD1870 
------------------------------------------------------------------------------------
112 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 13.45  LDD1870 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 13.45  LDD1870 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 12.55  LDD1870 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 12.55  LDD1870 
Apolipoprotein L2 (APOL2) LDTP11076 68.59  LDD1870 
Apolipoprotein L2 (APOL2) LDTP11076 68.59  LDD1870 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 18.25  LDD1870 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 18.25  LDD1870 
Calmodulin-3 (CALM3) LDTP02443 11.39  LDD1870 
Calmodulin-3 (CALM3) LDTP02443 11.39  LDD1870 
Caprin-1 (CAPRIN1) LDTP06121 9.19  LDD1870 
Caprin-1 (CAPRIN1) LDTP06121 9.19  LDD1870 
Centrin-2 (CETN2) LDTP03926 23.59  LDD1870 
Centrin-2 (CETN2) LDTP03926 23.59  LDD1870 
Clustered mitochondria protein homolog (CLUH) LDTP14486 10.48  LDD1870 
Clustered mitochondria protein homolog (CLUH) LDTP14486 10.48  LDD1870 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 13.27  LDD1870 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 13.27  LDD1870 
Dynactin subunit 3 (DCTN3) LDTP01359 9.00  LDD1870 
Dynactin subunit 3 (DCTN3) LDTP01359 9.00  LDD1870 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 32.00  LDD1870 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 32.00  LDD1870 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 11.24  LDD1870 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 11.24  LDD1870 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 13.93  LDD1870 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 13.93  LDD1870 
Integrator complex subunit 14 (INTS14) LDTP15834 8.51  LDD1870 
Integrator complex subunit 14 (INTS14) LDTP15834 8.51  LDD1870 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 12.30  LDD1870 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 12.30  LDD1870 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 32.45  LDD1870 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 32.45  LDD1870 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 9.65  LDD1870 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 9.65  LDD1870 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 14.42  LDD1870 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 14.42  LDD1870 
Microtubule-associated protein RP/EB family member 2 (MAPRE2) LDTP06413 9.25  LDD1870 
Microtubule-associated protein RP/EB family member 2 (MAPRE2) LDTP06413 9.25  LDD1870 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 8.88  LDD1870 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 8.88  LDD1870 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 46.53  LDD1870 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 46.53  LDD1870 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 16.34  LDD1870 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 16.34  LDD1870 
Negative elongation factor C/D (NELFCD) LDTP08594 10.41  LDD1870 
Negative elongation factor C/D (NELFCD) LDTP08594 10.41  LDD1870 
Neudesin (NENF) LDTP13630 13.00  LDD1870 
Neudesin (NENF) LDTP13630 13.00  LDD1870 
Nicastrin (NCSTN) LDTP09787 9.19  LDD1870 
Nicastrin (NCSTN) LDTP09787 9.19  LDD1870 
Nucleobindin-1 (NUCB1) LDTP05375 18.51  LDD1870 
Nucleobindin-1 (NUCB1) LDTP05375 18.51  LDD1870 
Nucleobindin-2 (NUCB2) LDTP05160 41.64  LDD1870 
Nucleobindin-2 (NUCB2) LDTP05160 41.64  LDD1870 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 9.45  LDD1870 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 9.45  LDD1870 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 8.46  LDD1870 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 8.46  LDD1870 
Optic atrophy 3 protein (OPA3) LDTP16006 10.27  LDD1870 
Optic atrophy 3 protein (OPA3) LDTP16006 10.27  LDD1870 
p53 and DNA damage-regulated protein 1 (PDRG1) LDTP16099 12.47  LDD1870 
p53 and DNA damage-regulated protein 1 (PDRG1) LDTP16099 12.47  LDD1870 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 15.35  LDD1870 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 15.35  LDD1870 
Pre-mRNA-splicing factor 38B (PRPF38B) LDTP17266 9.65  LDD1870 
Pre-mRNA-splicing factor 38B (PRPF38B) LDTP17266 9.65  LDD1870 
Protein FAM114A2 (FAM114A2) LDTP16080 11.24  LDD1870 
Protein FAM114A2 (FAM114A2) LDTP16080 11.24  LDD1870 
Protein FAM162A (FAM162A) LDTP10056 12.21  LDD1870 
Protein FAM162A (FAM162A) LDTP10056 12.21  LDD1870 
Protein flightless-1 homolog (FLII) LDTP05734 9.78  LDD1870 
Protein flightless-1 homolog (FLII) LDTP05734 9.78  LDD1870 
Protein SYS1 homolog (SYS1) LDTP08796 44.94  LDD1870 
Protein SYS1 homolog (SYS1) LDTP08796 44.94  LDD1870 
Protein unc-119 homolog B (UNC119B) LDTP00105 16.22  LDD1870 
Protein unc-119 homolog B (UNC119B) LDTP00105 16.22  LDD1870 
RAD50-interacting protein 1 (RINT1) LDTP07476 30.27  LDD1870 
RAD50-interacting protein 1 (RINT1) LDTP07476 30.27  LDD1870 
Reticulocalbin-2 (RCN2) LDTP06097 11.96  LDD1870 
Reticulocalbin-2 (RCN2) LDTP06097 11.96  LDD1870 
Reticulon-3 (RTN3) LDTP01522 17.51  LDD1870 
Reticulon-3 (RTN3) LDTP01522 17.51  LDD1870 
RNA-binding protein 12B (RBM12B) LDTP17640 25.63  LDD1870 
RNA-binding protein 12B (RBM12B) LDTP17640 25.63  LDD1870 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 13.93  LDD1870 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 13.93  LDD1870 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 16.11  LDD1870 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 16.11  LDD1870 
Synaptogyrin-2 (SYNGR2) LDTP00859 11.08  LDD1870 
Synaptogyrin-2 (SYNGR2) LDTP00859 11.08  LDD1870 
Syntaxin-18 (STX18) LDTP13086 19.16  LDD1870 
Syntaxin-18 (STX18) LDTP13086 19.16  LDD1870 
Tetraspanin-6 (TSPAN6) LDTP14458 26.72  LDD1870 
Tetraspanin-6 (TSPAN6) LDTP14458 26.72  LDD1870 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 10.70  LDD1870 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 10.70  LDD1870 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 10.34  LDD1870 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 10.34  LDD1870 
Torsin-1A-interacting protein 2 (TOR1AIP2) LDTP09215 8.57  LDD1870 
Torsin-1A-interacting protein 2 (TOR1AIP2) LDTP09215 8.57  LDD1870 
TraB domain-containing protein (TRABD) LDTP19963 15.03  LDD1870 
TraB domain-containing protein (TRABD) LDTP19963 15.03  LDD1870 
Transducin beta-like protein 2 (TBL2) LDTP16285 12.55  LDD1870 
Transducin beta-like protein 2 (TBL2) LDTP16285 12.55  LDD1870 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 44.94  LDD1870 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 44.94  LDD1870 
Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) LDTP01163 9.32  LDD1870 
Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) LDTP01163 9.32  LDD1870 
Uncharacterized protein KIAA2013 (KIAA2013) LDTP17652 10.63  LDD1870 
Uncharacterized protein KIAA2013 (KIAA2013) LDTP17652 10.63  LDD1870 
Zinc finger CCHC domain-containing protein 3 (ZCCHC3) LDTP12623 8.82  LDD1870 
Zinc finger CCHC domain-containing protein 3 (ZCCHC3) LDTP12623 8.82  LDD1870 
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⏷ Show the Full List of 112 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1870 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587