Details of the Probe

General Information of Probe

Probe ID
LDPC0518
Probe Name
C288
Probe Type
PAL-AfBPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 337.423
Lipid-water partition coefficient (xlogp) 2.73332
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C20H23N3O2
Canonical SMILES
C#CCCC1(CCNC(=O)C2C3CC2(c2ccccc2C)CO3)N=N1
InChI
InChI=1S/C20H23N3O2/c1-3-4-9-20(22-23-20)10-11-21-18(24)17-16-12-19(17,13-25-16)15-8-6-5-7-14(15)2/h1,5-8,16-17H,4,9-13H2,2H3,(H,21,24)
InChIKey
HHWHSAVFEWRJJK-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

135 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) LDTP12639 9.99  LDD1958 
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 7.21  LDD1958 
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 42.22  LDD1958 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 10.70  LDD1958 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 10.85  LDD1958 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 19.16  LDD1958 
Acid ceramidase (ASAH1) LDTP05905 15.14  LDD1958 
Acireductone dioxygenase (ADI1) LDTP11268 8.46  LDD1958 
ADP-dependent glucokinase (ADPGK) LDTP11127 8.75  LDD1958 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 48.50  LDD1958 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 8.57  LDD1958 
Alpha-galactosidase A (GLA) LDTP02141 6.50  LDD1958 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 7.11  LDD1958 
Antigen peptide transporter 1 (TAP1) LDTP05408 6.73  LDD1958 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 15.45  LDD1958 
Atlastin-2 (ATL2) LDTP09251 7.16  LDD1958 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 12.30  LDD1958 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 7.11  LDD1958 
Atypical kinase COQ8A, mitochondrial (COQ8A) LDTP09285 7.36  LDD1958 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 7.06  LDD1958 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 6.50  LDD1958 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 13.27  LDD1958 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 18.00  LDD1958 
Calcium-independent phospholipase A2-gamma (PNPLA8) LDTP12318 8.63  LDD1958 
Carbohydrate sulfotransferase 12 (CHST12) LDTP12494 6.19  LDD1958 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 17.63  LDD1958 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 8.75  LDD1958 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 23.43  LDD1958 
Ceramide synthase 2 (CERS2) LDTP10329 9.58  LDD1958 
Choline kinase alpha (CHKA) LDTP03787 7.01  LDD1958 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 12.13  LDD1958 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 7.06  LDD1958 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 22.01  LDD1958 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 7.94  LDD1958 
Cytochrome b5 type B (CYB5B) LDTP00697 23.26  LDD1958 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 7.11  LDD1958 
D-3-phosphoglycerate dehydrogenase (PHGDH) LDTP00701 11.00  LDD1958 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 10.34  LDD1958 
Dehydrodolichyl diphosphate synthase complex subunit DHDDS (DHDDS) LDTP08177 6.87  LDD1958 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 15.24  LDD1958 
Delta(24)-sterol reductase (DHCR24) LDTP06375 19.97  LDD1958 
Deoxyhypusine hydroxylase (DOHH) LDTP11225 10.06  LDD1958 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 6.54  LDD1958 
Dihydrofolate reductase (DHFR) LDTP01769 8.22  LDD1958 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 7.31  LDD1958 
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) LDTP11259 8.51  LDD1958 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 13.36  LDD1958 
E3 ubiquitin-protein ligase TRIM13 (TRIM13) LDTP01065 6.82  LDD1958 
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETFDH) LDTP06511 6.96  LDD1958 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 7.67  LDD1958 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 9.65  LDD1958 
Endoplasmic reticulum metallopeptidase 1 (ERMP1) LDTP08017 11.16  LDD1958 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 12.73  LDD1958 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 10.56  LDD1958 
Ethanolamine kinase 1 (ETNK1) LDTP12197 35.26  LDD1958 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 9.51  LDD1958 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 7.06  LDD1958 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 13.18  LDD1958 
Heme oxygenase 2 (HMOX2) LDTP03540 28.05  LDD1958 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 6.32  LDD1958 
Hexokinase-2 (HK2) LDTP04531 7.26  LDD1958 
Histone-lysine N-methyltransferase 2A (KMT2A) LDTP05396 7.36  LDD1958 
Holocytochrome c-type synthase (HCCS) LDTP04581 6.59  LDD1958 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 10.06  LDD1958 
L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) LDTP12105 8.51  LDD1958 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 10.48  LDD1958 
Lanosterol synthase (LSS) LDTP04183 6.82  LDD1958 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 7.41  LDD1958 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 16.91  LDD1958 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 9.78  LDD1958 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 6.73  LDD1958 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 8.22  LDD1958 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 10.27  LDD1958 
Lysosomal acid phosphatase (ACP2) LDTP02539 6.59  LDD1958 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 13.83  LDD1958 
Lysosomal protective protein (CTSA) LDTP02505 22.94  LDD1958 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 15.35  LDD1958 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 15.03  LDD1958 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 10.70  LDD1958 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 8.17  LDD1958 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 40.50  LDD1958 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 9.13  LDD1958 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 8.69  LDD1958 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 47.18  LDD1958 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 6.50  LDD1958 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 36.25  LDD1958 
Nardilysin (NRDC) LDTP00886 6.50  LDD1958 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 10.78  LDD1958 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 19.84  LDD1958 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 9.45  LDD1958 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 14.93  LDD1958 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 6.50  LDD1958 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 8.75  LDD1958 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 7.89  LDD1958 
Peroxisomal leader peptide-processing protease (TYSND1) LDTP06720 6.23  LDD1958 
Phosphatidate cytidylyltransferase 2 (CDS2) LDTP01649 6.68  LDD1958 
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (PTPMT1) LDTP09578 6.45  LDD1958 
Phospholipase A2 group XV (PLA2G15) LDTP09088 17.51  LDD1958 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 6.45  LDD1958 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 6.63  LDD1958 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 19.84  LDD1958 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 11.55  LDD1958 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 7.84  LDD1958 
Probable ATP-dependent RNA helicase DDX10 (DDX10) LDTP05785 8.00  LDD1958 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 14.42  LDD1958 
Prostaglandin reductase 1 (PTGR1) LDTP06227 11.24  LDD1958 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 18.77  LDD1958 
Proteasome subunit beta type-4 (PSMB4) LDTP03417 7.94  LDD1958 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 6.63  LDD1958 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 6.87  LDD1958 
Protein O-GlcNAcase (OGA) LDTP00988 6.68  LDD1958 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 11.96  LDD1958 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 12.91  LDD1958 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 10.34  LDD1958 
Rab-like protein 3 (RABL3) LDTP06986 8.34  LDD1958 
RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 6.63  LDD1958 
Ras-related protein Rab-24 (RAB24) LDTP10020 6.15  LDD1958 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 6.92  LDD1958 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 11.39  LDD1958 
Ribosomal protein S6 kinase alpha-1 (RPS6KA1) LDTP06384 6.92  LDD1958 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 16.80  LDD1958 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 15.14  LDD1958 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 11.08  LDD1958 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 9.85  LDD1958 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 7.26  LDD1958 
Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) LDTP07227 7.78  LDD1958 
Tissue alpha-L-fucosidase (FUCA1) LDTP02006 6.32  LDD1958 
TLC domain-containing protein 1 (TLCD1) LDTP10182 12.82  LDD1958 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 7.67  LDD1958 
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (TRMT61A) LDTP10320 6.68  LDD1958 
tRNA (uracil-5-)-methyltransferase homolog A (TRMT2A) LDTP08687 7.73  LDD1958 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 9.00  LDD1958 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 6.23  LDD1958 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 28.25  LDD1958 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 7.26  LDD1958 
------------------------------------------------------------------------------------
⏷ Show the Full List of 135 Enzyme
96 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 17.88  LDD1958 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 8.22  LDD1958 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 10.34  LDD1958 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 7.16  LDD1958 
ATP synthase subunit a (MT-ATP6) LDTP01804 21.41  LDD1958 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 16.80  LDD1958 
BOS complex subunit NCLN (NCLN) LDTP10036 38.05  LDD1958 
BRI3-binding protein (BRI3BP) LDTP15648 19.56  LDD1958 
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (COX16) LDTP16163 26.72  LDD1958 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 6.41  LDD1958 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 7.73  LDD1958 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 8.28  LDD1958 
Derlin-1 (DERL1) LDTP11245 11.63  LDD1958 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 6.73  LDD1958 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 20.25  LDD1958 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 19.84  LDD1958 
Essential MCU regulator, mitochondrial (SMDT1) LDTP11927 9.00  LDD1958 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 8.57  LDD1958 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 7.41  LDD1958 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 11.79  LDD1958 
H(+)/Cl(-) exchange transporter 7 (CLCN7) LDTP04463 9.13  LDD1958 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 13.83  LDD1958 
Integral membrane protein 2B (ITM2B) LDTP13833 10.63  LDD1958 
Integral membrane protein 2C (ITM2C) LDTP12451 6.50  LDD1958 
Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) LDTP01100 13.18  LDD1958 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 8.51  LDD1958 
Lysosomal-associated transmembrane protein 4A (LAPTM4A) LDTP06275 18.64  LDD1958 
Lysosome membrane protein 2 (SCARB2) LDTP06034 11.79  LDD1958 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 7.11  LDD1958 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 7.52  LDD1958 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 6.87  LDD1958 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 13.55  LDD1958 
Metal transporter CNNM3 (CNNM3) LDTP09144 6.15  LDD1958 
Metaxin-1 (MTX1) LDTP05900 10.20  LDD1958 
Methylosome subunit pICln (CLNS1A) LDTP04597 7.26  LDD1958 
MICOS complex subunit MIC26 (APOO) LDTP11250 7.41  LDD1958 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 7.94  LDD1958 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 11.71  LDD1958 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 9.58  LDD1958 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 7.73  LDD1958 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 13.00  LDD1958 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 20.53  LDD1958 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 16.80  LDD1958 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 12.13  LDD1958 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 12.64  LDD1958 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 10.27  LDD1958 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 31.12  LDD1958 
Mpv17-like protein 2 (MPV17L2) LDTP14952 8.57  LDD1958 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 10.41  LDD1958 
Nucleoporin NDC1 (NDC1) LDTP11213 8.69  LDD1958 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 6.68  LDD1958 
Peroxisomal membrane protein 11A (PEX11A) LDTP01160 9.00  LDD1958 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 7.11  LDD1958 
Peroxisomal membrane protein PEX16 (PEX16) LDTP14181 7.36  LDD1958 
Prosaposin (PSAP) LDTP02215 14.52  LDD1958 
Protein ARV1 (ARV1) LDTP11812 7.16  LDD1958 
Protein GPR107 (GPR107) LDTP07236 29.45  LDD1958 
Protein GPR108 (GPR108) LDTP12383 14.42  LDD1958 
Protein spinster homolog 1 (SPNS1) LDTP11844 14.32  LDD1958 
Protein tweety homolog 3 (TTYH3) LDTP11615 16.45  LDD1958 
Protein wntless homolog (WLS) LDTP07156 6.36  LDD1958 
Protein YIPF3 (YIPF3) LDTP11626 8.51  LDD1958 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 8.17  LDD1958 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 15.67  LDD1958 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 11.39  LDD1958 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 14.93  LDD1958 
Signal recognition particle subunit SRP68 (SRP68) LDTP13262 9.71  LDD1958 
Sodium bicarbonate cotransporter 3 (SLC4A7) LDTP14275 6.15  LDD1958 
Solute carrier family 25 member 16 (SLC25A16) LDTP14636 7.52  LDD1958 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 11.47  LDD1958 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 13.74  LDD1958 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 6.82  LDD1958 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 14.93  LDD1958 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 10.63  LDD1958 
Surfeit locus protein 4 (SURF4) LDTP00592 6.68  LDD1958 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 8.17  LDD1958 
Syntaxin-6 (STX6) LDTP00857 6.45  LDD1958 
Tetraspanin-10 (TSPAN10) LDTP15967 8.57  LDD1958 
Tetraspanin-3 (TSPAN3) LDTP16813 27.86  LDD1958 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 21.71  LDD1958 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 22.32  LDD1958 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 8.11  LDD1958 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 13.18  LDD1958 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 10.27  LDD1958 
Transmembrane protein 126A (TMEM126A) LDTP15948 34.78  LDD1958 
Transmembrane protein 160 (TMEM160) LDTP20002 41.93  LDD1958 
Transmembrane protein 199 (TMEM199) LDTP08881 17.75  LDD1958 
Transmembrane protein 205 (TMEM205) LDTP07667 6.73  LDD1958 
Transmembrane protein 230 (TMEM230) LDTP10065 9.92  LDD1958 
Transmembrane protein 59 (TMEM59) LDTP11406 9.78  LDD1958 
Transmembrane protein 87A (TMEM87A) LDTP15481 18.38  LDD1958 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 6.23  LDD1958 
Vang-like protein 1 (VANGL1) LDTP09288 6.50  LDD1958 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 20.11  LDD1958 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 15.14  LDD1958 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 6.36  LDD1958 
------------------------------------------------------------------------------------
⏷ Show the Full List of 96 Transporter and channel
90 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 13.45  LDD1958 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 10.56  LDD1958 
Ankyrin repeat domain-containing protein 54 (ANKRD54) LDTP15104 43.71  LDD1958 
Apolipoprotein L2 (APOL2) LDTP11076 15.78  LDD1958 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 11.24  LDD1958 
Cell division control protein 45 homolog (CDC45) LDTP01213 6.28  LDD1958 
Centrosomal protein 43 (CEP43) LDTP01652 10.78  LDD1958 
Charged multivesicular body protein 5 (CHMP5) LDTP12948 6.92  LDD1958 
Clustered mitochondria protein homolog (CLUH) LDTP14486 16.45  LDD1958 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 6.19  LDD1958 
Conserved oligomeric Golgi complex subunit 3 (COG3) LDTP10452 7.31  LDD1958 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 8.28  LDD1958 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 10.34  LDD1958 
Dynactin subunit 3 (DCTN3) LDTP01359 6.77  LDD1958 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 8.00  LDD1958 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 19.03  LDD1958 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 16.22  LDD1958 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 12.47  LDD1958 
Gem-associated protein 8 (GEMIN8) LDTP12746 9.00  LDD1958 
Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) LDTP00729 7.41  LDD1958 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 12.82  LDD1958 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 6.15  LDD1958 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 11.00  LDD1958 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 7.36  LDD1958 
Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) LDTP04714 6.15  LDD1958 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 7.41  LDD1958 
HIG1 domain family member 1A, mitochondrial (HIGD1A) LDTP13797 7.78  LDD1958 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 7.31  LDD1958 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 9.45  LDD1958 
KIF-binding protein (KIFBP) LDTP10263 10.48  LDD1958 
Large proline-rich protein BAG6 (BAG6) LDTP04094 11.24  LDD1958 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 12.13  LDD1958 
Large ribosomal subunit protein mL64 (GADD45GIP1) LDTP09297 6.50  LDD1958 
Lipase maturation factor 2 (LMF2) LDTP15887 7.06  LDD1958 
Lipid droplet assembly factor 1 (LDAF1) LDTP10116 8.51  LDD1958 
Lipid droplet-regulating VLDL assembly factor AUP1 (AUP1) LDTP14217 6.63  LDD1958 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 7.78  LDD1958 
Matrix-remodeling-associated protein 7 (MXRA7) LDTP17003 8.57  LDD1958 
Mdm2-binding protein (MTBP) LDTP15714 6.36  LDD1958 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 11.00  LDD1958 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 6.45  LDD1958 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 17.51  LDD1958 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 14.93  LDD1958 
Mitochondrial import receptor subunit TOM7 homolog (TOMM7) LDTP12982 7.06  LDD1958 
Negative elongation factor C/D (NELFCD) LDTP08594 13.64  LDD1958 
Nischarin (NISCH) LDTP13870 7.62  LDD1958 
Nucleobindin-1 (NUCB1) LDTP05375 10.56  LDD1958 
Nucleobindin-2 (NUCB2) LDTP05160 25.99  LDD1958 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 8.22  LDD1958 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 6.19  LDD1958 
Optic atrophy 3 protein (OPA3) LDTP16006 34.54  LDD1958 
p53 and DNA damage-regulated protein 1 (PDRG1) LDTP16099 7.84  LDD1958 
Paraneoplastic antigen Ma2 (PNMA2) LDTP13517 6.87  LDD1958 
Peroxisomal membrane protein 11C (PEX11G) LDTP10381 13.45  LDD1958 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 12.38  LDD1958 
Protein CEBPZOS (CEBPZOS) LDTP18883 8.94  LDD1958 
Protein CutA (CUTA) LDTP01075 10.93  LDD1958 
Protein FAM114A2 (FAM114A2) LDTP16080 13.64  LDD1958 
Protein FAM162A (FAM162A) LDTP10056 11.39  LDD1958 
Protein Hikeshi (HIKESHI) LDTP06892 12.21  LDD1958 
Protein jagunal homolog 1 (JAGN1) LDTP08904 8.75  LDD1958 
Protein LYRIC (MTDH) LDTP08224 7.16  LDD1958 
Protein unc-119 homolog B (UNC119B) LDTP00105 19.84  LDD1958 
Protein YIF1B (YIF1B) LDTP06948 10.78  LDD1958 
Rap guanine nucleotide exchange factor 2 (RAPGEF2) LDTP14058 6.68  LDD1958 
Reticulocalbin-2 (RCN2) LDTP06097 8.06  LDD1958 
Reticulon-3 (RTN3) LDTP01522 21.86  LDD1958 
Reticulon-4 (RTN4) LDTP12412 6.23  LDD1958 
Retinol-binding protein 1 (RBP1) LDTP02345 8.51  LDD1958 
RNA-binding protein FUS (FUS) LDTP03775 6.82  LDD1958 
RNA-binding protein with multiple splicing (RBPMS) LDTP09970 7.01  LDD1958 
RUS family member 1 (RUSF1) LDTP10357 8.82  LDD1958 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 9.00  LDD1958 
Synaptogyrin-2 (SYNGR2) LDTP00859 6.68  LDD1958 
Syntaxin-10 (STX10) LDTP00986 9.38  LDD1958 
Syntaxin-18 (STX18) LDTP13086 13.00  LDD1958 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 6.41  LDD1958 
Tetraspanin-6 (TSPAN6) LDTP14458 14.62  LDD1958 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 10.85  LDD1958 
TraB domain-containing protein (TRABD) LDTP19963 8.17  LDD1958 
Trophoblast glycoprotein (TPBG) LDTP05960 6.32  LDD1958 
Tubulin beta-3 chain (TUBB3) LDTP05904 9.19  LDD1958 
Tudor and KH domain-containing protein (TDRKH) LDTP13922 7.94  LDD1958 
Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) LDTP15634 8.34  LDD1958 
Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) LDTP01163 6.41  LDD1958 
Uncharacterized protein KIAA2013 (KIAA2013) LDTP17652 11.55  LDD1958 
UPF0449 protein C19orf25 (C19orf25) LDTP13214 12.91  LDD1958 
UPF0488 protein C8orf33 (C8orf33) LDTP12025 6.96  LDD1958 
UPF0729 protein C18orf32 (C18orf32) LDTP15599 12.47  LDD1958 
Vang-like protein 2 (VANGL2) LDTP13560 10.85  LDD1958 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1958 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587