Details of the Probe

General Information of Probe

Probe ID
LDPC0301
Probe Name
C041
Synonyms
Z4225935647
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 387.5
Lipid-water partition coefficient (xlogp) 3.1
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C20H25N3O3S
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-1-(4-methylphenyl)sulfonylcyclopentane-1-carboxamide
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)C2(CCCC2)C(=O)NCCC3(N=N3)CCC#C
InChI
InChI=1S/C20H25N3O3S/c1-3-4-13-20(22-23-20)14-15-21-18(24)19(11-5-6-12-19)27(25,26)17-9-7-16(2)8-10-17/h1,7-10H,4-6,11-15H2,2H3,(H,21,24)
InChIKey
KLERTFBYZKBXRV-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

124 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 32.90  LDD1741 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 9.25  LDD1741 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 14.93  LDD1741 
7-dehydrocholesterol reductase (DHCR7) LDTP13131 7.21  LDD1741 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 9.85  LDD1741 
Acid ceramidase (ASAH1) LDTP05905 16.56  LDD1741 
ADP-dependent glucokinase (ADPGK) LDTP11127 6.54  LDD1741 
ADP-ribosylation factor-like protein 2 (ARL2) LDTP03805 24.93  LDD1741 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 7.84  LDD1741 
Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) LDTP03560 5.94  LDD1741 
Alpha-galactosidase A (GLA) LDTP02141 6.87  LDD1741 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 6.87  LDD1741 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 5.90  LDD1741 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 6.45  LDD1741 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 7.36  LDD1741 
Beta-galactosidase (GLB1) LDTP02837 15.35  LDD1741 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 9.51  LDD1741 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 18.38  LDD1741 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 12.13  LDD1741 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 14.03  LDD1741 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 14.32  LDD1741 
Cathepsin B (CTSB) LDTP02223 15.35  LDD1741 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 6.82  LDD1741 
Cell division cycle protein 27 homolog (CDC27) LDTP03525 7.21  LDD1741 
Ceramide synthase 1 (CERS1) LDTP03394 18.25  LDD1741 
Ceramide synthase 2 (CERS2) LDTP10329 11.47  LDD1741 
Choline kinase alpha (CHKA) LDTP03787 10.48  LDD1741 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 18.64  LDD1741 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 13.74  LDD1741 
Cytochrome b5 type B (CYB5B) LDTP00697 9.25  LDD1741 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 7.26  LDD1741 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 9.85  LDD1741 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 6.41  LDD1741 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 13.55  LDD1741 
Delta(24)-sterol reductase (DHCR24) LDTP06375 8.57  LDD1741 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 10.56  LDD1741 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 6.06  LDD1741 
Dihydrofolate reductase (DHFR) LDTP01769 35.02  LDD1741 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 11.55  LDD1741 
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) LDTP11259 5.78  LDD1741 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 6.59  LDD1741 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 6.68  LDD1741 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 7.06  LDD1741 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 9.38  LDD1741 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 6.82  LDD1741 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 13.27  LDD1741 
Epoxide hydrolase 1 (EPHX1) LDTP02175 9.06  LDD1741 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 13.83  LDD1741 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 7.26  LDD1741 
Heme oxygenase 1 (HMOX1) LDTP02359 11.55  LDD1741 
Heme oxygenase 2 (HMOX2) LDTP03540 46.85  LDD1741 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 7.84  LDD1741 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 6.50  LDD1741 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 5.94  LDD1741 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 6.96  LDD1741 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 9.85  LDD1741 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 19.84  LDD1741 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 6.59  LDD1741 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 9.58  LDD1741 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 8.22  LDD1741 
Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) LDTP03858 10.78  LDD1741 
Lysosomal acid phosphatase (ACP2) LDTP02539 10.56  LDD1741 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 23.75  LDD1741 
Lysosomal protective protein (CTSA) LDTP02505 13.09  LDD1741 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 18.00  LDD1741 
Mannosyl-oligosaccharide glucosidase (MOGS) LDTP05971 7.94  LDD1741 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 11.55  LDD1741 
Minor histocompatibility antigen H13 (HM13) LDTP09396 7.11  LDD1741 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 6.77  LDD1741 
Mitochondrial ubiquitin ligase activator of NFKB 1 (MUL1) LDTP10038 6.23  LDD1741 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 6.06  LDD1741 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 5.66  LDD1741 
N-alpha-acetyltransferase 40 (NAA40) LDTP08265 5.98  LDD1741 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 34.54  LDD1741 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 5.90  LDD1741 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 10.20  LDD1741 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 23.43  LDD1741 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 12.73  LDD1741 
NADPH--cytochrome P450 reductase (POR) LDTP02848 5.58  LDD1741 
Oxidized purine nucleoside triphosphate hydrolase (NUDT1) LDTP03816 5.94  LDD1741 
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (CPOX) LDTP03813 5.78  LDD1741 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 17.75  LDD1741 
Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) LDTP10101 6.28  LDD1741 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 12.30  LDD1741 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 5.82  LDD1741 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 10.93  LDD1741 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 5.70  LDD1741 
Phospholipase A-2-activating protein (PLAA) LDTP13814 11.47  LDD1741 
Phospholipase A2 group XV (PLA2G15) LDTP09088 22.94  LDD1741 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 8.06  LDD1741 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 11.16  LDD1741 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 16.34  LDD1741 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 24.59  LDD1741 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 8.75  LDD1741 
Prostaglandin reductase 2 (PTGR2) LDTP08979 10.63  LDD1741 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 18.00  LDD1741 
Proteasome subunit beta type-4 (PSMB4) LDTP03417 9.38  LDD1741 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 7.57  LDD1741 
Protein O-GlcNAcase (OGA) LDTP00988 8.88  LDD1741 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 19.29  LDD1741 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 11.88  LDD1741 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 18.00  LDD1741 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 29.86  LDD1741 
Ribonuclease T2 (RNASET2) LDTP00316 6.28  LDD1741 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 12.73  LDD1741 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 20.39  LDD1741 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 5.66  LDD1741 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PPP2R1B) LDTP03523 6.59  LDD1741 
Serine/threonine-protein phosphatase 6 catalytic subunit (PPP6C) LDTP00333 9.00  LDD1741 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 23.26  LDD1741 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 10.48  LDD1741 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 8.06  LDD1741 
Soluble calcium-activated nucleotidase 1 (CANT1) LDTP09620 6.54  LDD1741 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 8.34  LDD1741 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 8.63  LDD1741 
Squalene monooxygenase (SQLE) LDTP06142 6.32  LDD1741 
Squalene synthase (FDFT1) LDTP03842 19.43  LDD1741 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 5.74  LDD1741 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 8.88  LDD1741 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 11.88  LDD1741 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 5.62  LDD1741 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 6.50  LDD1741 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 9.06  LDD1741 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 15.35  LDD1741 
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⏷ Show the Full List of 124 Enzyme
72 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 10.93  LDD1741 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 8.34  LDD1741 
Amyloid-beta precursor protein (APP) LDTP02071 7.36  LDD1741 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 7.26  LDD1741 
ATP synthase subunit e, mitochondrial (ATP5ME) LDTP14717 6.23  LDD1741 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 24.93  LDD1741 
BRI3-binding protein (BRI3BP) LDTP15648 11.88  LDD1741 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 8.00  LDD1741 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 25.28  LDD1741 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 9.19  LDD1741 
Derlin-1 (DERL1) LDTP11245 8.63  LDD1741 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 5.70  LDD1741 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 17.03  LDD1741 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 6.15  LDD1741 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 8.22  LDD1741 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 8.46  LDD1741 
Lysosome membrane protein 2 (SCARB2) LDTP06034 36.00  LDD1741 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 6.82  LDD1741 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 6.11  LDD1741 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 9.45  LDD1741 
Metal transporter CNNM4 (CNNM4) LDTP07537 5.86  LDD1741 
Metaxin-1 (MTX1) LDTP05900 21.56  LDD1741 
Metaxin-3 (MTX3) LDTP14970 10.93  LDD1741 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 11.08  LDD1741 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 7.41  LDD1741 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 12.13  LDD1741 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 35.75  LDD1741 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 33.36  LDD1741 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 15.03  LDD1741 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 5.70  LDD1741 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 6.23  LDD1741 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 14.93  LDD1741 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 29.04  LDD1741 
Mpv17-like protein 2 (MPV17L2) LDTP14952 11.39  LDD1741 
Nucleoporin NDC1 (NDC1) LDTP11213 8.34  LDD1741 
Prosaposin (PSAP) LDTP02215 6.36  LDD1741 
Protein FAM8A1 (FAM8A1) LDTP16190 7.46  LDD1741 
Protein GPR107 (GPR107) LDTP07236 17.88  LDD1741 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 5.86  LDD1741 
Protein tweety homolog 3 (TTYH3) LDTP11615 18.00  LDD1741 
Protein wntless homolog (WLS) LDTP07156 5.82  LDD1741 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 8.11  LDD1741 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 15.89  LDD1741 
Sideroflexin-4 (SFXN4) LDTP07531 5.98  LDD1741 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 13.74  LDD1741 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 20.53  LDD1741 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 18.13  LDD1741 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 19.16  LDD1741 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 8.17  LDD1741 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 5.74  LDD1741 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 8.57  LDD1741 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 8.51  LDD1741 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 6.06  LDD1741 
Tetraspanin-3 (TSPAN3) LDTP16813 14.93  LDD1741 
Transferrin receptor protein 1 (TFRC) LDTP01969 5.86  LDD1741 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 15.56  LDD1741 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 26.54  LDD1741 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 11.88  LDD1741 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 7.62  LDD1741 
Transmembrane protein 126A (TMEM126A) LDTP15948 14.32  LDD1741 
Transmembrane protein 14C (TMEM14C) LDTP12979 5.54  LDD1741 
Transmembrane protein 160 (TMEM160) LDTP20002 13.36  LDD1741 
Transmembrane protein 199 (TMEM199) LDTP08881 20.25  LDD1741 
Transmembrane protein 230 (TMEM230) LDTP10065 7.94  LDD1741 
Transmembrane protein 59 (TMEM59) LDTP11406 6.19  LDD1741 
Transmembrane protein 87A (TMEM87A) LDTP15481 9.32  LDD1741 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 8.11  LDD1741 
V-type proton ATPase subunit S1 (ATP6AP1) LDTP06499 5.62  LDD1741 
Vang-like protein 1 (VANGL1) LDTP09288 10.78  LDD1741 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 25.99  LDD1741 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 15.78  LDD1741 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 5.74  LDD1741 
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⏷ Show the Full List of 72 Transporter and channel
3 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 7.21  LDD1741 
SAP30-binding protein (SAP30BP) LDTP13305 5.66  LDD1741 
Y-box-binding protein 1 (YBX1) LDTP05065 6.54  LDD1741 
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73 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 8.28  LDD1741 
Apolipoprotein L2 (APOL2) LDTP11076 35.26  LDD1741 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 6.45  LDD1741 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 11.00  LDD1741 
Calumenin (CALU) LDTP00887 6.77  LDD1741 
Centrin-2 (CETN2) LDTP03926 8.00  LDD1741 
Clustered mitochondria protein homolog (CLUH) LDTP14486 12.91  LDD1741 
Cold-inducible RNA-binding protein (CIRBP) LDTP06022 5.70  LDD1741 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 21.86  LDD1741 
DDRGK domain-containing protein 1 (DDRGK1) LDTP10403 5.62  LDD1741 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 9.38  LDD1741 
DnaJ homolog subfamily C member 8 (DNAJC8) LDTP01361 6.19  LDD1741 
Dymeclin (DYM) LDTP08000 5.90  LDD1741 
Dynactin subunit 3 (DCTN3) LDTP01359 8.00  LDD1741 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 7.16  LDD1741 
Emerin (EMD) LDTP04356 5.62  LDD1741 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 6.23  LDD1741 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 12.38  LDD1741 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 44.94  LDD1741 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 20.39  LDD1741 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 9.00  LDD1741 
Ganglioside GM2 activator (GM2A) LDTP02927 5.78  LDD1741 
Golgi apparatus protein 1 (GLG1) LDTP09920 7.84  LDD1741 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 11.79  LDD1741 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 6.96  LDD1741 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 5.66  LDD1741 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 5.86  LDD1741 
HIG1 domain family member 1A, mitochondrial (HIGD1A) LDTP13797 15.03  LDD1741 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 11.31  LDD1741 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 12.64  LDD1741 
Large proline-rich protein BAG6 (BAG6) LDTP04094 9.13  LDD1741 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 15.45  LDD1741 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 6.32  LDD1741 
Matrix-remodeling-associated protein 7 (MXRA7) LDTP17003 5.74  LDD1741 
Mitochondrial import receptor subunit TOM20 homolog (TOMM20) LDTP06373 6.50  LDD1741 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 75.58  LDD1741 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 35.26  LDD1741 
Neudesin (NENF) LDTP13630 16.00  LDD1741 
Neuferricin (CYB5D2) LDTP15623 7.73  LDD1741 
Nucleobindin-1 (NUCB1) LDTP05375 33.59  LDD1741 
Nucleobindin-2 (NUCB2) LDTP05160 41.64  LDD1741 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 8.69  LDD1741 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 6.73  LDD1741 
Optic atrophy 3 protein (OPA3) LDTP16006 11.24  LDD1741 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 6.06  LDD1741 
Programmed cell death protein 5 (PDCD5) LDTP00417 8.22  LDD1741 
Proline-rich protein PRCC (PRCC) LDTP09850 6.28  LDD1741 
Protein CEBPZOS (CEBPZOS) LDTP18883 12.73  LDD1741 
Protein CutA (CUTA) LDTP01075 6.50  LDD1741 
Protein FAM114A2 (FAM114A2) LDTP16080 8.34  LDD1741 
Protein FAM162A (FAM162A) LDTP10056 13.09  LDD1741 
Protein FAM177A1 (FAM177A1) LDTP15398 5.98  LDD1741 
Protein jagunal homolog 1 (JAGN1) LDTP08904 6.23  LDD1741 
Protein LYRIC (MTDH) LDTP08224 6.15  LDD1741 
Protein unc-119 homolog B (UNC119B) LDTP00105 19.29  LDD1741 
Regulator of microtubule dynamics protein 1 (RMDN1) LDTP10209 5.94  LDD1741 
Reticulocalbin-2 (RCN2) LDTP06097 9.06  LDD1741 
Reticulon-2 (RTN2) LDTP01167 6.54  LDD1741 
Reticulon-3 (RTN3) LDTP01522 7.78  LDD1741 
Reticulon-4 (RTN4) LDTP12412 7.46  LDD1741 
RNA-binding motif protein, X chromosome (RBMX) LDTP03850 6.82  LDD1741 
RNA-binding protein 10 (RBM10) LDTP05224 7.26  LDD1741 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 6.11  LDD1741 
Small integral membrane protein 12 (SMIM12) LDTP19859 9.13  LDD1741 
Synaptogyrin-2 (SYNGR2) LDTP00859 7.62  LDD1741 
Syntaxin-10 (STX10) LDTP00986 7.06  LDD1741 
Syntaxin-18 (STX18) LDTP13086 14.62  LDD1741 
Tetraspanin-6 (TSPAN6) LDTP14458 14.62  LDD1741 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 8.22  LDD1741 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 6.41  LDD1741 
TraB domain-containing protein (TRABD) LDTP19963 10.13  LDD1741 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 11.63  LDD1741 
Vimentin (VIM) LDTP02297 7.06  LDD1741 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1741 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587