Details of the Probe

General Information of Probe

Probe ID
LDPC0334
Probe Name
C082
Synonyms
Z4282859870
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 404.5
Lipid-water partition coefficient (xlogp) 2.9
Rotatable Bond Count (rotbonds) 10
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C20H28N4O3S
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-[5-(diethylsulfamoyl)-2,3-dimethylphenyl]propanamide
Canonical SMILES
CCN(CC)S(=O)(=O)C1=CC(=C(C(=C1)C)C)NC(=O)CCC2(N=N2)CCC#C
InChI
InChI=1S/C20H28N4O3S/c1-6-9-11-20(22-23-20)12-10-19(25)21-18-14-17(13-15(4)16(18)5)28(26,27)24(7-2)8-3/h1,13-14H,7-12H2,2-5H3,(H,21,25)
InChIKey
OFEAEQOSRTUCPM-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

158 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) LDTP06657 5.54  LDD1774 
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) LDTP06657 5.54  LDD1774 
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 5.28  LDD1774 
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 5.28  LDD1774 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 7.11  LDD1774 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 7.11  LDD1774 
Acid ceramidase (ASAH1) LDTP05905 5.24  LDD1774 
Acid ceramidase (ASAH1) LDTP05905 5.24  LDD1774 
Adenosine deaminase (ADA) LDTP01803 19.56  LDD1774 
Adenosine deaminase (ADA) LDTP01803 19.56  LDD1774 
ADP-dependent glucokinase (ADPGK) LDTP11127 5.62  LDD1774 
ADP-dependent glucokinase (ADPGK) LDTP11127 5.62  LDD1774 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 6.50  LDD1774 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 6.50  LDD1774 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 6.82  LDD1774 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 6.82  LDD1774 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 5.62  LDD1774 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 5.62  LDD1774 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 11.08  LDD1774 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 11.08  LDD1774 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 5.13  LDD1774 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 5.13  LDD1774 
Beta-galactosidase (GLB1) LDTP02837 5.94  LDD1774 
Beta-galactosidase (GLB1) LDTP02837 5.94  LDD1774 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 7.31  LDD1774 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 7.31  LDD1774 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 9.00  LDD1774 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 9.00  LDD1774 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 7.21  LDD1774 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 7.21  LDD1774 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 5.43  LDD1774 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 5.43  LDD1774 
Ceramide synthase 1 (CERS1) LDTP03394 5.70  LDD1774 
Ceramide synthase 1 (CERS1) LDTP03394 5.70  LDD1774 
Ceramide synthase 2 (CERS2) LDTP10329 6.06  LDD1774 
Ceramide synthase 2 (CERS2) LDTP10329 6.06  LDD1774 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 9.19  LDD1774 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 9.19  LDD1774 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 9.58  LDD1774 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 9.58  LDD1774 
Cytochrome b5 type B (CYB5B) LDTP00697 17.27  LDD1774 
Cytochrome b5 type B (CYB5B) LDTP00697 17.27  LDD1774 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 7.73  LDD1774 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 7.73  LDD1774 
Delta(24)-sterol reductase (DHCR24) LDTP06375 5.90  LDD1774 
Delta(24)-sterol reductase (DHCR24) LDTP06375 5.90  LDD1774 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 9.71  LDD1774 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 9.71  LDD1774 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 5.70  LDD1774 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 5.70  LDD1774 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 6.45  LDD1774 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 6.45  LDD1774 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 11.63  LDD1774 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 11.63  LDD1774 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 12.38  LDD1774 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 12.38  LDD1774 
Epoxide hydrolase 1 (EPHX1) LDTP02175 18.77  LDD1774 
Epoxide hydrolase 1 (EPHX1) LDTP02175 18.77  LDD1774 
Exonuclease 1 (EXO1) LDTP13751 10.06  LDD1774 
Exonuclease 1 (EXO1) LDTP13751 10.06  LDD1774 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 10.70  LDD1774 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 10.70  LDD1774 
Glutathione hydrolase 7 (GGT7) LDTP13367 5.17  LDD1774 
Glutathione hydrolase 7 (GGT7) LDTP13367 5.17  LDD1774 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 5.28  LDD1774 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 5.28  LDD1774 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 9.65  LDD1774 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 9.65  LDD1774 
Heme oxygenase 1 (HMOX1) LDTP02359 11.31  LDD1774 
Heme oxygenase 1 (HMOX1) LDTP02359 11.31  LDD1774 
Heme oxygenase 2 (HMOX2) LDTP03540 12.30  LDD1774 
Heme oxygenase 2 (HMOX2) LDTP03540 12.30  LDD1774 
Histone-lysine N-methyltransferase SMYD3 (SMYD3) LDTP12020 5.90  LDD1774 
Histone-lysine N-methyltransferase SMYD3 (SMYD3) LDTP12020 5.90  LDD1774 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 7.16  LDD1774 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 7.16  LDD1774 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 12.04  LDD1774 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 12.04  LDD1774 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 5.90  LDD1774 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 5.90  LDD1774 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 31.56  LDD1774 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 31.56  LDD1774 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 6.23  LDD1774 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 6.23  LDD1774 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 7.67  LDD1774 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 7.67  LDD1774 
Lysosomal alpha-glucosidase (GAA) LDTP02486 5.62  LDD1774 
Lysosomal alpha-glucosidase (GAA) LDTP02486 5.62  LDD1774 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 10.63  LDD1774 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 10.63  LDD1774 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 8.75  LDD1774 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 8.75  LDD1774 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 6.19  LDD1774 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 6.19  LDD1774 
Minor histocompatibility antigen H13 (HM13) LDTP09396 12.55  LDD1774 
Minor histocompatibility antigen H13 (HM13) LDTP09396 12.55  LDD1774 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 4.96  LDD1774 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 4.96  LDD1774 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 7.11  LDD1774 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 7.11  LDD1774 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 17.39  LDD1774 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 17.39  LDD1774 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 7.57  LDD1774 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 7.57  LDD1774 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 9.13  LDD1774 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 9.13  LDD1774 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 9.25  LDD1774 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 9.25  LDD1774 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 8.40  LDD1774 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 8.40  LDD1774 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 4.96  LDD1774 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 4.96  LDD1774 
Phospholipase A2 group XV (PLA2G15) LDTP09088 8.06  LDD1774 
Phospholipase A2 group XV (PLA2G15) LDTP09088 8.06  LDD1774 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 5.24  LDD1774 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 5.24  LDD1774 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 31.78  LDD1774 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 31.78  LDD1774 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 15.14  LDD1774 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 15.14  LDD1774 
Prostaglandin reductase 2 (PTGR2) LDTP08979 8.46  LDD1774 
Prostaglandin reductase 2 (PTGR2) LDTP08979 8.46  LDD1774 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 9.25  LDD1774 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 9.25  LDD1774 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 6.87  LDD1774 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 6.87  LDD1774 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 10.06  LDD1774 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 10.06  LDD1774 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 7.84  LDD1774 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 7.84  LDD1774 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 6.45  LDD1774 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 6.45  LDD1774 
RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 5.74  LDD1774 
RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 5.74  LDD1774 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 16.56  LDD1774 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 16.56  LDD1774 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 5.54  LDD1774 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 5.54  LDD1774 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 16.56  LDD1774 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 16.56  LDD1774 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 4.99  LDD1774 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 4.99  LDD1774 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 5.54  LDD1774 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 5.54  LDD1774 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 9.13  LDD1774 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 9.13  LDD1774 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 12.73  LDD1774 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 12.73  LDD1774 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 9.45  LDD1774 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 9.45  LDD1774 
Ubiquitin carboxyl-terminal hydrolase 47 (USP47) LDTP10495 5.10  LDD1774 
Ubiquitin carboxyl-terminal hydrolase 47 (USP47) LDTP10495 5.10  LDD1774 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 14.03  LDD1774 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 14.03  LDD1774 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 5.10  LDD1774 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 5.10  LDD1774 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 8.40  LDD1774 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 8.40  LDD1774 
------------------------------------------------------------------------------------
⏷ Show the Full List of 158 Enzyme
118 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 7.62  LDD1774 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 7.62  LDD1774 
ATP synthase subunit a (MT-ATP6) LDTP01804 8.94  LDD1774 
ATP synthase subunit a (MT-ATP6) LDTP01804 8.94  LDD1774 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 14.62  LDD1774 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 14.62  LDD1774 
B-cell receptor-associated protein 29 (BCAP29) LDTP16201 6.68  LDD1774 
B-cell receptor-associated protein 29 (BCAP29) LDTP16201 6.68  LDD1774 
BRI3-binding protein (BRI3BP) LDTP15648 7.67  LDD1774 
BRI3-binding protein (BRI3BP) LDTP15648 7.67  LDD1774 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 5.17  LDD1774 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 5.17  LDD1774 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 22.94  LDD1774 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 22.94  LDD1774 
Derlin-1 (DERL1) LDTP11245 6.96  LDD1774 
Derlin-1 (DERL1) LDTP11245 6.96  LDD1774 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 26.91  LDD1774 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 26.91  LDD1774 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 5.46  LDD1774 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 5.46  LDD1774 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 5.70  LDD1774 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 5.70  LDD1774 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 6.06  LDD1774 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 6.06  LDD1774 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 5.31  LDD1774 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 5.31  LDD1774 
Lysosome membrane protein 2 (SCARB2) LDTP06034 15.03  LDD1774 
Lysosome membrane protein 2 (SCARB2) LDTP06034 15.03  LDD1774 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 5.31  LDD1774 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 5.31  LDD1774 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 5.46  LDD1774 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 5.46  LDD1774 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 13.18  LDD1774 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 13.18  LDD1774 
Metaxin-1 (MTX1) LDTP05900 6.28  LDD1774 
Metaxin-1 (MTX1) LDTP05900 6.28  LDD1774 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 9.45  LDD1774 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 9.45  LDD1774 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 8.06  LDD1774 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 8.06  LDD1774 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 5.50  LDD1774 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 5.50  LDD1774 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 31.34  LDD1774 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 31.34  LDD1774 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 22.32  LDD1774 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 22.32  LDD1774 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 6.28  LDD1774 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 6.28  LDD1774 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 7.06  LDD1774 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 7.06  LDD1774 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 5.21  LDD1774 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 5.21  LDD1774 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 15.67  LDD1774 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 15.67  LDD1774 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 5.90  LDD1774 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 5.90  LDD1774 
Mpv17-like protein 2 (MPV17L2) LDTP14952 16.68  LDD1774 
Mpv17-like protein 2 (MPV17L2) LDTP14952 16.68  LDD1774 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 10.56  LDD1774 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 10.56  LDD1774 
Nuclear pore complex protein Nup93 (NUP93) LDTP08769 6.50  LDD1774 
Nuclear pore complex protein Nup93 (NUP93) LDTP08769 6.50  LDD1774 
Nucleoporin NDC1 (NDC1) LDTP11213 7.01  LDD1774 
Nucleoporin NDC1 (NDC1) LDTP11213 7.01  LDD1774 
Prosaposin (PSAP) LDTP02215 7.01  LDD1774 
Prosaposin (PSAP) LDTP02215 7.01  LDD1774 
Protein FAM8A1 (FAM8A1) LDTP16190 5.86  LDD1774 
Protein FAM8A1 (FAM8A1) LDTP16190 5.86  LDD1774 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 4.92  LDD1774 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 4.92  LDD1774 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 12.13  LDD1774 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 12.13  LDD1774 
Reduced folate transporter (SLC19A1) LDTP03952 4.99  LDD1774 
Reduced folate transporter (SLC19A1) LDTP03952 4.99  LDD1774 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 5.66  LDD1774 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 5.66  LDD1774 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 11.63  LDD1774 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 11.63  LDD1774 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 5.58  LDD1774 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 5.58  LDD1774 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 10.41  LDD1774 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 10.41  LDD1774 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 7.41  LDD1774 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 7.41  LDD1774 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 6.87  LDD1774 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 6.87  LDD1774 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 9.32  LDD1774 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 9.32  LDD1774 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 6.82  LDD1774 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 6.82  LDD1774 
Tetraspanin-10 (TSPAN10) LDTP15967 11.39  LDD1774 
Tetraspanin-10 (TSPAN10) LDTP15967 11.39  LDD1774 
Tetraspanin-3 (TSPAN3) LDTP16813 8.63  LDD1774 
Tetraspanin-3 (TSPAN3) LDTP16813 8.63  LDD1774 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 7.57  LDD1774 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 7.57  LDD1774 
Translocator protein (TSPO) LDTP03546 13.93  LDD1774 
Translocator protein (TSPO) LDTP03546 13.93  LDD1774 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 16.22  LDD1774 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 16.22  LDD1774 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 5.74  LDD1774 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 5.74  LDD1774 
Transmembrane protein 126A (TMEM126A) LDTP15948 9.38  LDD1774 
Transmembrane protein 126A (TMEM126A) LDTP15948 9.38  LDD1774 
Transmembrane protein 160 (TMEM160) LDTP20002 9.00  LDD1774 
Transmembrane protein 160 (TMEM160) LDTP20002 9.00  LDD1774 
Transmembrane protein 199 (TMEM199) LDTP08881 19.97  LDD1774 
Transmembrane protein 199 (TMEM199) LDTP08881 19.97  LDD1774 
Transmembrane protein 230 (TMEM230) LDTP10065 5.82  LDD1774 
Transmembrane protein 230 (TMEM230) LDTP10065 5.82  LDD1774 
Transmembrane protein 87A (TMEM87A) LDTP15481 25.11  LDD1774 
Transmembrane protein 87A (TMEM87A) LDTP15481 25.11  LDD1774 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 19.70  LDD1774 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 19.70  LDD1774 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 29.24  LDD1774 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 29.24  LDD1774 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 16.11  LDD1774 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 16.11  LDD1774 
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⏷ Show the Full List of 118 Transporter and channel
4 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 6.54  LDD1774 
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 6.54  LDD1774 
Y-box-binding protein 1 (YBX1) LDTP05065 4.99  LDD1774 
Y-box-binding protein 1 (YBX1) LDTP05065 4.99  LDD1774 
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86 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 7.46  LDD1774 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 7.46  LDD1774 
Apolipoprotein L2 (APOL2) LDTP11076 39.95  LDD1774 
Apolipoprotein L2 (APOL2) LDTP11076 39.95  LDD1774 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 6.96  LDD1774 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 6.96  LDD1774 
Centrosomal protein 43 (CEP43) LDTP01652 5.78  LDD1774 
Centrosomal protein 43 (CEP43) LDTP01652 5.78  LDD1774 
Clustered mitochondria protein homolog (CLUH) LDTP14486 7.21  LDD1774 
Clustered mitochondria protein homolog (CLUH) LDTP14486 7.21  LDD1774 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 11.63  LDD1774 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 11.63  LDD1774 
Dymeclin (DYM) LDTP08000 5.17  LDD1774 
Dymeclin (DYM) LDTP08000 5.17  LDD1774 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 8.82  LDD1774 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 8.82  LDD1774 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 10.20  LDD1774 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 10.20  LDD1774 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 10.63  LDD1774 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 10.63  LDD1774 
Engulfment and cell motility protein 2 (ELMO2) LDTP10469 7.67  LDD1774 
Engulfment and cell motility protein 2 (ELMO2) LDTP10469 7.67  LDD1774 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 19.29  LDD1774 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 19.29  LDD1774 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 12.13  LDD1774 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 12.13  LDD1774 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 4.99  LDD1774 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 4.99  LDD1774 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 6.06  LDD1774 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 6.06  LDD1774 
Large proline-rich protein BAG6 (BAG6) LDTP04094 5.58  LDD1774 
Large proline-rich protein BAG6 (BAG6) LDTP04094 5.58  LDD1774 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 7.01  LDD1774 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 7.01  LDD1774 
Mediator of RNA polymerase II transcription subunit 25 (MED25) LDTP07906 6.41  LDD1774 
Mediator of RNA polymerase II transcription subunit 25 (MED25) LDTP07906 6.41  LDD1774 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 9.71  LDD1774 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 9.71  LDD1774 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 30.91  LDD1774 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 30.91  LDD1774 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 17.51  LDD1774 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 17.51  LDD1774 
Neudesin (NENF) LDTP13630 8.88  LDD1774 
Neudesin (NENF) LDTP13630 8.88  LDD1774 
Nucleobindin-1 (NUCB1) LDTP05375 10.13  LDD1774 
Nucleobindin-1 (NUCB1) LDTP05375 10.13  LDD1774 
Nucleobindin-2 (NUCB2) LDTP05160 25.28  LDD1774 
Nucleobindin-2 (NUCB2) LDTP05160 25.28  LDD1774 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 5.70  LDD1774 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 5.70  LDD1774 
Nurim (NRM) LDTP08606 6.68  LDD1774 
Nurim (NRM) LDTP08606 6.68  LDD1774 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 4.99  LDD1774 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 4.99  LDD1774 
Optic atrophy 3 protein (OPA3) LDTP16006 5.78  LDD1774 
Optic atrophy 3 protein (OPA3) LDTP16006 5.78  LDD1774 
Protein CEBPZOS (CEBPZOS) LDTP18883 10.48  LDD1774 
Protein CEBPZOS (CEBPZOS) LDTP18883 10.48  LDD1774 
Protein FAM114A2 (FAM114A2) LDTP16080 7.11  LDD1774 
Protein FAM114A2 (FAM114A2) LDTP16080 7.11  LDD1774 
Protein FAM162A (FAM162A) LDTP10056 6.54  LDD1774 
Protein FAM162A (FAM162A) LDTP10056 6.54  LDD1774 
Protein LYRIC (MTDH) LDTP08224 6.19  LDD1774 
Protein LYRIC (MTDH) LDTP08224 6.19  LDD1774 
Protein unc-119 homolog A (UNC119) LDTP05868 4.99  LDD1774 
Protein unc-119 homolog A (UNC119) LDTP05868 4.99  LDD1774 
Protein unc-119 homolog B (UNC119B) LDTP00105 9.25  LDD1774 
Protein unc-119 homolog B (UNC119B) LDTP00105 9.25  LDD1774 
Reticulocalbin-2 (RCN2) LDTP06097 6.15  LDD1774 
Reticulocalbin-2 (RCN2) LDTP06097 6.15  LDD1774 
Reticulon-3 (RTN3) LDTP01522 7.94  LDD1774 
Reticulon-3 (RTN3) LDTP01522 7.94  LDD1774 
Reticulon-4 (RTN4) LDTP12412 7.57  LDD1774 
Reticulon-4 (RTN4) LDTP12412 7.57  LDD1774 
Syntaxin-18 (STX18) LDTP13086 8.82  LDD1774 
Syntaxin-18 (STX18) LDTP13086 8.82  LDD1774 
Tetraspanin-6 (TSPAN6) LDTP14458 10.78  LDD1774 
Tetraspanin-6 (TSPAN6) LDTP14458 10.78  LDD1774 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 7.67  LDD1774 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 7.67  LDD1774 
TraB domain-containing protein (TRABD) LDTP19963 6.87  LDD1774 
TraB domain-containing protein (TRABD) LDTP19963 6.87  LDD1774 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 23.75  LDD1774 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 23.75  LDD1774 
Zinc finger SWIM domain-containing protein 8 (ZSWIM8) LDTP00121 5.50  LDD1774 
Zinc finger SWIM domain-containing protein 8 (ZSWIM8) LDTP00121 5.50  LDD1774 
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⏷ Show the Full List of 86 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1774 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587