Details of the Probe

General Information of Probe

Probe ID
LDPC0644
Probe Name
C429
Synonyms
Z4282859884
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 366.5
Lipid-water partition coefficient (xlogp) 3.7
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C20H22N4OS
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-[1-[4-(2-methyl-1,3-thiazol-4-yl)phenyl]ethyl]propanamide
Canonical SMILES
CC1=NC(=CS1)C2=CC=C(C=C2)C(C)NC(=O)CCC3(N=N3)CCC#C
InChI
InChI=1S/C20H22N4OS/c1-4-5-11-20(23-24-20)12-10-19(25)21-14(2)16-6-8-17(9-7-16)18-13-26-15(3)22-18/h1,6-9,13-14H,5,10-12H2,2-3H3,(H,21,25)
InChIKey
GMKGSOYOCSKHDW-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

119 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) LDTP12639 14.93  LDD2084 
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 17.88  LDD2084 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 15.35  LDD2084 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 21.86  LDD2084 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 28.25  LDD2084 
Acid ceramidase (ASAH1) LDTP05905 16.80  LDD2084 
ADP-dependent glucokinase (ADPGK) LDTP11127 25.28  LDD2084 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 12.21  LDD2084 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 17.51  LDD2084 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 12.64  LDD2084 
All-trans-retinol 13,14-reductase (RETSAT) LDTP15097 17.15  LDD2084 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 12.55  LDD2084 
Antigen peptide transporter 2 (TAP2) LDTP05409 11.31  LDD2084 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 29.45  LDD2084 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 15.89  LDD2084 
Beta-galactosidase (GLB1) LDTP02837 13.18  LDD2084 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 30.70  LDD2084 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 27.86  LDD2084 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 15.35  LDD2084 
Catechol O-methyltransferase (COMT) LDTP03145 11.63  LDD2084 
Cell division cycle protein 23 homolog (CDC23) LDTP13408 11.39  LDD2084 
Ceramide synthase 1 (CERS1) LDTP03394 21.26  LDD2084 
Ceramide synthase 2 (CERS2) LDTP10329 23.92  LDD2084 
Complex I assembly factor ACAD9, mitochondrial (ACAD9) LDTP12048 15.35  LDD2084 
Copper-transporting ATPase 2 (ATP7B) LDTP03779 13.64  LDD2084 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 28.44  LDD2084 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 30.91  LDD2084 
Cytochrome b5 type B (CYB5B) LDTP00697 54.19  LDD2084 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 21.11  LDD2084 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 54.19  LDD2084 
Delta(24)-sterol reductase (DHCR24) LDTP06375 22.63  LDD2084 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 15.56  LDD2084 
Deoxyhypusine hydroxylase (DOHH) LDTP11225 16.34  LDD2084 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 12.47  LDD2084 
Dihydrofolate reductase (DHFR) LDTP01769 29.24  LDD2084 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 11.16  LDD2084 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 10.93  LDD2084 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 11.96  LDD2084 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 29.86  LDD2084 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 28.84  LDD2084 
Epoxide hydrolase 1 (EPHX1) LDTP02175 25.63  LDD2084 
ERO1-like protein alpha (ERO1A) LDTP10386 11.63  LDD2084 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 12.21  LDD2084 
Flavin reductase (NADPH) (BLVRB) LDTP03511 30.27  LDD2084 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 41.93  LDD2084 
Heme oxygenase 1 (HMOX1) LDTP02359 23.59  LDD2084 
Heme oxygenase 2 (HMOX2) LDTP03540 76.64  LDD2084 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 11.39  LDD2084 
Hexokinase-2 (HK2) LDTP04531 14.22  LDD2084 
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (PDE8A) LDTP01018 18.51  LDD2084 
Histone-lysine N-methyltransferase 2A (KMT2A) LDTP05396 16.56  LDD2084 
Holocytochrome c-type synthase (HCCS) LDTP04581 21.41  LDD2084 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 17.51  LDD2084 
Ketosamine-3-kinase (FN3KRP) LDTP16025 11.71  LDD2084 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 11.79  LDD2084 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 21.71  LDD2084 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 43.41  LDD2084 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 15.89  LDD2084 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 15.89  LDD2084 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 35.51  LDD2084 
Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) LDTP03858 12.55  LDD2084 
Lysosomal acid phosphatase (ACP2) LDTP02539 17.15  LDD2084 
Lysosomal alpha-glucosidase (GAA) LDTP02486 23.92  LDD2084 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 53.08  LDD2084 
Lysosomal protective protein (CTSA) LDTP02505 54.19  LDD2084 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 35.51  LDD2084 
Methionine aminopeptidase 1 (METAP1) LDTP04565 13.74  LDD2084 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 22.47  LDD2084 
Minor histocompatibility antigen H13 (HM13) LDTP09396 19.97  LDD2084 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 14.72  LDD2084 
N-alpha-acetyltransferase 40 (NAA40) LDTP08265 13.09  LDD2084 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 23.92  LDD2084 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 14.72  LDD2084 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 11.00  LDD2084 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 12.38  LDD2084 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 39.40  LDD2084 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 15.56  LDD2084 
NADH-ubiquinone oxidoreductase chain 5 (MT-ND5) LDTP01986 11.88  LDD2084 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 59.71  LDD2084 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 17.15  LDD2084 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 14.22  LDD2084 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 11.96  LDD2084 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 11.16  LDD2084 
Peroxisomal trans-2-enoyl-CoA reductase (PECR) LDTP11437 18.77  LDD2084 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 28.84  LDD2084 
Phospholipase A2 group XV (PLA2G15) LDTP09088 17.15  LDD2084 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 14.32  LDD2084 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 35.26  LDD2084 
Prostaglandin reductase 3 (PTGR3) LDTP15422 19.56  LDD2084 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 27.47  LDD2084 
Proteasome subunit beta type-4 (PSMB4) LDTP03417 13.93  LDD2084 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 15.03  LDD2084 
Protein arginine N-methyltransferase 3 (PRMT3) LDTP01028 14.12  LDD2084 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 29.24  LDD2084 
Protein O-GlcNAcase (OGA) LDTP00988 15.67  LDD2084 
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGNT2) LDTP09031 13.09  LDD2084 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 22.94  LDD2084 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 26.35  LDD2084 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 43.11  LDD2084 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 22.78  LDD2084 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 74.54  LDD2084 
Ribosomal protein S6 kinase alpha-1 (RPS6KA1) LDTP06384 11.55  LDD2084 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 34.06  LDD2084 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 13.55  LDD2084 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 11.63  LDD2084 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 15.89  LDD2084 
Short-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADS) LDTP02833 12.04  LDD2084 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 13.09  LDD2084 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 13.64  LDD2084 
Squalene synthase (FDFT1) LDTP03842 12.13  LDD2084 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 15.56  LDD2084 
Thioredoxin-like protein 1 (TXNL1) LDTP00758 11.08  LDD2084 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 57.28  LDD2084 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 29.04  LDD2084 
Ubiquitin carboxyl-terminal hydrolase 28 (USP28) LDTP10785 11.08  LDD2084 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 11.96  LDD2084 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 29.45  LDD2084 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 19.97  LDD2084 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 14.93  LDD2084 
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⏷ Show the Full List of 119 Enzyme
75 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 24.25  LDD2084 
ATP synthase subunit a (MT-ATP6) LDTP01804 36.00  LDD2084 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 22.94  LDD2084 
BOS complex subunit NCLN (NCLN) LDTP10036 70.03  LDD2084 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 99.73  LDD2084 
Derlin-1 (DERL1) LDTP11245 12.82  LDD2084 
Essential MCU regulator, mitochondrial (SMDT1) LDTP11927 52.71  LDD2084 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 15.35  LDD2084 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 18.90  LDD2084 
Integral membrane protein 2C (ITM2C) LDTP12451 16.11  LDD2084 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 12.91  LDD2084 
Lysosome membrane protein 2 (SCARB2) LDTP06034 40.50  LDD2084 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 14.22  LDD2084 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 12.38  LDD2084 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 42.52  LDD2084 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 13.74  LDD2084 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 12.82  LDD2084 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 20.97  LDD2084 
Metaxin-1 (MTX1) LDTP05900 21.41  LDD2084 
Metaxin-3 (MTX3) LDTP14970 12.47  LDD2084 
MFS-type transporter SLC18B1 (SLC18B1) LDTP07462 46.21  LDD2084 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 27.28  LDD2084 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 19.56  LDD2084 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 11.55  LDD2084 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 12.91  LDD2084 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 30.91  LDD2084 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 41.64  LDD2084 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 99.73  LDD2084 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 99.73  LDD2084 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 43.11  LDD2084 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 16.34  LDD2084 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 16.56  LDD2084 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 17.39  LDD2084 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 37.27  LDD2084 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 13.27  LDD2084 
Mpv17-like protein 2 (MPV17L2) LDTP14952 20.25  LDD2084 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 22.94  LDD2084 
Nucleoporin NDC1 (NDC1) LDTP11213 21.56  LDD2084 
Occludin (OCLN) LDTP06581 12.38  LDD2084 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 12.91  LDD2084 
Peroxisomal biogenesis factor 3 (PEX3) LDTP04749 10.93  LDD2084 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 60.97  LDD2084 
Prosaposin (PSAP) LDTP02215 34.78  LDD2084 
Protein FAM8A1 (FAM8A1) LDTP16190 19.84  LDD2084 
Protein GPR107 (GPR107) LDTP07236 77.71  LDD2084 
Protein GPR108 (GPR108) LDTP12383 17.15  LDD2084 
Protein spinster homolog 1 (SPNS1) LDTP11844 18.13  LDD2084 
Protein tweety homolog 3 (TTYH3) LDTP11615 46.85  LDD2084 
Proton-coupled amino acid transporter 1 (SLC36A1) LDTP08016 14.12  LDD2084 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 30.27  LDD2084 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 16.45  LDD2084 
Reduced folate transporter (SLC19A1) LDTP03952 11.08  LDD2084 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 56.10  LDD2084 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 21.26  LDD2084 
Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15) LDTP11826 13.18  LDD2084 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 22.78  LDD2084 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 25.11  LDD2084 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 13.00  LDD2084 
Transferrin receptor protein 1 (TFRC) LDTP01969 14.62  LDD2084 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 33.36  LDD2084 
Translocator protein (TSPO) LDTP03546 32.67  LDD2084 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 32.90  LDD2084 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 16.34  LDD2084 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 12.30  LDD2084 
Transmembrane protein 126A (TMEM126A) LDTP15948 37.27  LDD2084 
Transmembrane protein 160 (TMEM160) LDTP20002 54.95  LDD2084 
Transmembrane protein 199 (TMEM199) LDTP08881 52.71  LDD2084 
Transmembrane protein 205 (TMEM205) LDTP07667 11.71  LDD2084 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 15.45  LDD2084 
V-type proton ATPase subunit S1 (ATP6AP1) LDTP06499 11.16  LDD2084 
Vacuole membrane protein 1 (VMP1) LDTP10343 18.38  LDD2084 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 56.49  LDD2084 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 71.51  LDD2084 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 17.03  LDD2084 
Zinc transporter 7 (SLC30A7) LDTP09180 21.56  LDD2084 
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⏷ Show the Full List of 75 Transporter and channel
1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
IgG receptor FcRn large subunit p51 (FCGRT) LDTP04720 15.67  LDD2084 
------------------------------------------------------------------------------------
86 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Alpha-internexin (INA) LDTP06527 11.24  LDD2084 
Anaphase-promoting complex subunit 16 (ANAPC16) LDTP10213 12.21  LDD2084 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 18.38  LDD2084 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 13.64  LDD2084 
Calumenin (CALU) LDTP00887 15.35  LDD2084 
Centrin-2 (CETN2) LDTP03926 11.55  LDD2084 
Centrosomal protein 43 (CEP43) LDTP01652 12.64  LDD2084 
Cleavage stimulation factor subunit 3 (CSTF3) LDTP05719 10.93  LDD2084 
Clustered mitochondria protein homolog (CLUH) LDTP14486 37.01  LDD2084 
Cold-inducible RNA-binding protein (CIRBP) LDTP06022 12.04  LDD2084 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 63.56  LDD2084 
DDRGK domain-containing protein 1 (DDRGK1) LDTP10403 11.55  LDD2084 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 15.14  LDD2084 
DNA replication complex GINS protein PSF2 (GINS2) LDTP13802 12.13  LDD2084 
Dynactin subunit 3 (DCTN3) LDTP01359 24.59  LDD2084 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 56.10  LDD2084 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 51.98  LDD2084 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 12.13  LDD2084 
Galectin-3-binding protein (LGALS3BP) LDTP05558 16.45  LDD2084 
Ganglioside GM2 activator (GM2A) LDTP02927 19.56  LDD2084 
Golgi apparatus protein 1 (GLG1) LDTP09920 11.47  LDD2084 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 44.02  LDD2084 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 11.16  LDD2084 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 11.55  LDD2084 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 13.18  LDD2084 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 17.39  LDD2084 
Large proline-rich protein BAG6 (BAG6) LDTP04094 14.32  LDD2084 
Large ribosomal subunit protein mL45 (MRPL45) LDTP15863 18.38  LDD2084 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 63.56  LDD2084 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 10.93  LDD2084 
m-AAA protease-interacting protein 1, mitochondrial (MAIP1) LDTP09644 12.91  LDD2084 
Mdm2-binding protein (MTBP) LDTP15714 16.11  LDD2084 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 11.71  LDD2084 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 14.32  LDD2084 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 34.54  LDD2084 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 11.47  LDD2084 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD2084 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 51.27  LDD2084 
Mitochondrial import receptor subunit TOM6 homolog (TOMM6) LDTP10113 35.75  LDD2084 
Myomegalin (PDE4DIP) LDTP07221 14.93  LDD2084 
NEDD8 ultimate buster 1 (NUB1) LDTP14104 13.55  LDD2084 
Neudesin (NENF) LDTP13630 28.25  LDD2084 
Neuferricin (CYB5D2) LDTP15623 32.45  LDD2084 
Neurofilament light polypeptide (NEFL) LDTP02180 12.82  LDD2084 
Nucleobindin-1 (NUCB1) LDTP05375 99.73  LDD2084 
Nucleobindin-2 (NUCB2) LDTP05160 31.34  LDD2084 
Nurim (NRM) LDTP08606 19.43  LDD2084 
Optic atrophy 3 protein (OPA3) LDTP16006 23.59  LDD2084 
Oxysterol-binding protein-related protein 3 (OSBPL3) LDTP11930 12.04  LDD2084 
Peflin (PEF1) LDTP13167 12.04  LDD2084 
Polyamine-modulated factor 1 (PMF1) LDTP07508 12.64  LDD2084 
Polymerase delta-interacting protein 2 (POLDIP2) LDTP13906 11.16  LDD2084 
Protein bicaudal D homolog 2 (BICD2) LDTP09410 13.09  LDD2084 
Protein CEBPZOS (CEBPZOS) LDTP18883 17.27  LDD2084 
Protein CUSTOS (CUSTOS) LDTP18134 16.68  LDD2084 
Protein FAM114A2 (FAM114A2) LDTP16080 23.10  LDD2084 
Protein FAM162A (FAM162A) LDTP10056 19.84  LDD2084 
Protein FAM177A1 (FAM177A1) LDTP15398 15.45  LDD2084 
Protein FAM3C (FAM3C) LDTP09773 14.62  LDD2084 
Protein jagunal homolog 1 (JAGN1) LDTP08904 15.03  LDD2084 
Protein LYRIC (MTDH) LDTP08224 14.72  LDD2084 
Protein SET (SET) LDTP05277 24.93  LDD2084 
Protein unc-119 homolog B (UNC119B) LDTP00105 22.32  LDD2084 
Protein UXT (UXT) LDTP13125 13.36  LDD2084 
Protein YIF1A (YIF1A) LDTP01494 11.63  LDD2084 
RAD50-interacting protein 1 (RINT1) LDTP07476 19.97  LDD2084 
Reticulocalbin-2 (RCN2) LDTP06097 29.24  LDD2084 
Reticulon-3 (RTN3) LDTP01522 45.89  LDD2084 
Reticulon-4 (RTN4) LDTP12412 15.14  LDD2084 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 14.42  LDD2084 
Small integral membrane protein 12 (SMIM12) LDTP19859 25.28  LDD2084 
Synaptogyrin-2 (SYNGR2) LDTP00859 17.27  LDD2084 
Syntaxin-18 (STX18) LDTP13086 15.03  LDD2084 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 13.45  LDD2084 
Testis-expressed protein 264 (TEX264) LDTP14259 21.41  LDD2084 
Tetraspanin-6 (TSPAN6) LDTP14458 41.07  LDD2084 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 16.80  LDD2084 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 24.25  LDD2084 
TraB domain-containing protein (TRABD) LDTP19963 13.55  LDD2084 
Translation initiation factor eIF2B subunit epsilon (EIF2B5) LDTP05765 12.73  LDD2084 
Transmembrane protein 209 (TMEM209) LDTP18272 11.71  LDD2084 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 36.00  LDD2084 
UPF0488 protein C8orf33 (C8orf33) LDTP12025 15.56  LDD2084 
Vacuolar protein sorting-associated protein 18 homolog (VPS18) LDTP13019 14.72  LDD2084 
Vimentin (VIM) LDTP02297 12.38  LDD2084 
Zinc finger CCHC domain-containing protein 3 (ZCCHC3) LDTP12623 16.11  LDD2084 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD2084 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587