Details of the Probe

General Information of Probe

Probe ID
LDPC0618
Probe Name
C399
Synonyms
Z4225957111
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 339.4
Lipid-water partition coefficient (xlogp) 3.3
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C17H17N5OS
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-4-(2-methylphenyl)thiadiazole-5-carboxamide
Canonical SMILES
CC1=CC=CC=C1C2=C(SN=N2)C(=O)NCCC3(N=N3)CCC#C
InChI
InChI=1S/C17H17N5OS/c1-3-4-9-17(20-21-17)10-11-18-16(23)15-14(19-22-24-15)13-8-6-5-7-12(13)2/h1,5-8H,4,9-11H2,2H3,(H,18,23)
InChIKey
WEKBLCIKQXZENX-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

188 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 11.47  LDD2058 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 11.47  LDD2058 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 12.64  LDD2058 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 12.64  LDD2058 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 12.64  LDD2058 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 12.64  LDD2058 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 12.82  LDD2058 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 12.82  LDD2058 
Acid ceramidase (ASAH1) LDTP05905 10.63  LDD2058 
Acid ceramidase (ASAH1) LDTP05905 10.63  LDD2058 
Adenosine deaminase (ADA) LDTP01803 16.45  LDD2058 
Adenosine deaminase (ADA) LDTP01803 16.45  LDD2058 
Adenosine kinase (ADK) LDTP04689 7.62  LDD2058 
Adenosine kinase (ADK) LDTP04689 7.62  LDD2058 
ADP-dependent glucokinase (ADPGK) LDTP11127 11.96  LDD2058 
ADP-dependent glucokinase (ADPGK) LDTP11127 11.96  LDD2058 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 9.71  LDD2058 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 9.71  LDD2058 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 9.65  LDD2058 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 9.65  LDD2058 
Atlastin-2 (ATL2) LDTP09251 6.82  LDD2058 
Atlastin-2 (ATL2) LDTP09251 6.82  LDD2058 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 6.73  LDD2058 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 6.73  LDD2058 
Beta-galactosidase (GLB1) LDTP02837 11.79  LDD2058 
Beta-galactosidase (GLB1) LDTP02837 11.79  LDD2058 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 8.94  LDD2058 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 8.94  LDD2058 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 12.21  LDD2058 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 12.21  LDD2058 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 17.15  LDD2058 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 17.15  LDD2058 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 9.65  LDD2058 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 9.65  LDD2058 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 17.03  LDD2058 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 17.03  LDD2058 
Ceramide glucosyltransferase (UGCG) LDTP06617 14.03  LDD2058 
Ceramide glucosyltransferase (UGCG) LDTP06617 14.03  LDD2058 
Ceramide synthase 2 (CERS2) LDTP10329 7.94  LDD2058 
Ceramide synthase 2 (CERS2) LDTP10329 7.94  LDD2058 
Choline kinase alpha (CHKA) LDTP03787 16.91  LDD2058 
Choline kinase alpha (CHKA) LDTP03787 16.91  LDD2058 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 12.30  LDD2058 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 12.30  LDD2058 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 13.09  LDD2058 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 13.09  LDD2058 
Cytochrome b5 type B (CYB5B) LDTP00697 22.47  LDD2058 
Cytochrome b5 type B (CYB5B) LDTP00697 22.47  LDD2058 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 7.73  LDD2058 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 7.73  LDD2058 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 26.91  LDD2058 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 26.91  LDD2058 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 8.63  LDD2058 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 8.63  LDD2058 
Delta(24)-sterol reductase (DHCR24) LDTP06375 7.31  LDD2058 
Delta(24)-sterol reductase (DHCR24) LDTP06375 7.31  LDD2058 
Dihydrofolate reductase (DHFR) LDTP01769 10.63  LDD2058 
Dihydrofolate reductase (DHFR) LDTP01769 10.63  LDD2058 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 8.63  LDD2058 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 8.63  LDD2058 
E3 ubiquitin-protein ligase NEDD4 (NEDD4) LDTP04114 7.26  LDD2058 
E3 ubiquitin-protein ligase NEDD4 (NEDD4) LDTP04114 7.26  LDD2058 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 9.32  LDD2058 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 9.32  LDD2058 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 9.00  LDD2058 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 9.00  LDD2058 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 9.78  LDD2058 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 9.78  LDD2058 
Epoxide hydrolase 1 (EPHX1) LDTP02175 9.00  LDD2058 
Epoxide hydrolase 1 (EPHX1) LDTP02175 9.00  LDD2058 
Ethanolaminephosphotransferase 1 (SELENOI) LDTP11606 6.68  LDD2058 
Ethanolaminephosphotransferase 1 (SELENOI) LDTP11606 6.68  LDD2058 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 12.82  LDD2058 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 12.82  LDD2058 
Ferrochelatase, mitochondrial (FECH) LDTP03198 9.25  LDD2058 
Ferrochelatase, mitochondrial (FECH) LDTP03198 9.25  LDD2058 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 11.79  LDD2058 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 11.79  LDD2058 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 9.85  LDD2058 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 9.85  LDD2058 
Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) LDTP17305 11.39  LDD2058 
Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) LDTP17305 11.39  LDD2058 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 8.94  LDD2058 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 8.94  LDD2058 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 18.38  LDD2058 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 18.38  LDD2058 
Heme oxygenase 1 (HMOX1) LDTP02359 24.25  LDD2058 
Heme oxygenase 1 (HMOX1) LDTP02359 24.25  LDD2058 
Heme oxygenase 2 (HMOX2) LDTP03540 18.77  LDD2058 
Heme oxygenase 2 (HMOX2) LDTP03540 18.77  LDD2058 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 11.55  LDD2058 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 11.55  LDD2058 
Histone deacetylase complex subunit SAP130 (SAP130) LDTP11703 7.89  LDD2058 
Histone deacetylase complex subunit SAP130 (SAP130) LDTP11703 7.89  LDD2058 
Histone-lysine N-methyltransferase NSD2 (NSD2) LDTP01759 7.84  LDD2058 
Histone-lysine N-methyltransferase NSD2 (NSD2) LDTP01759 7.84  LDD2058 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 14.62  LDD2058 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 14.62  LDD2058 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 8.88  LDD2058 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 8.88  LDD2058 
Legumain (LGMN) LDTP10888 7.62  LDD2058 
Legumain (LGMN) LDTP10888 7.62  LDD2058 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 17.03  LDD2058 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 17.03  LDD2058 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 8.63  LDD2058 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 8.63  LDD2058 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 11.96  LDD2058 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 11.96  LDD2058 
Lysosomal acid phosphatase (ACP2) LDTP02539 7.16  LDD2058 
Lysosomal acid phosphatase (ACP2) LDTP02539 7.16  LDD2058 
Lysosomal alpha-glucosidase (GAA) LDTP02486 7.62  LDD2058 
Lysosomal alpha-glucosidase (GAA) LDTP02486 7.62  LDD2058 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 11.31  LDD2058 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 11.31  LDD2058 
Lysosomal protective protein (CTSA) LDTP02505 13.64  LDD2058 
Lysosomal protective protein (CTSA) LDTP02505 13.64  LDD2058 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 13.93  LDD2058 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 13.93  LDD2058 
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) LDTP10930 7.31  LDD2058 
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) LDTP10930 7.31  LDD2058 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 9.92  LDD2058 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 9.92  LDD2058 
N-alpha-acetyltransferase 35, NatC auxiliary subunit (NAA35) LDTP07259 12.47  LDD2058 
N-alpha-acetyltransferase 35, NatC auxiliary subunit (NAA35) LDTP07259 12.47  LDD2058 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 6.68  LDD2058 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 6.68  LDD2058 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 7.21  LDD2058 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 7.21  LDD2058 
NAD-capped RNA hydrolase NUDT12 (NUDT12) LDTP11081 21.26  LDD2058 
NAD-capped RNA hydrolase NUDT12 (NUDT12) LDTP11081 21.26  LDD2058 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 7.52  LDD2058 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 7.52  LDD2058 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 20.11  LDD2058 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 20.11  LDD2058 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 20.97  LDD2058 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 20.97  LDD2058 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 66.72  LDD2058 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 66.72  LDD2058 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 21.26  LDD2058 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 21.26  LDD2058 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 7.89  LDD2058 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 7.89  LDD2058 
Phospholipase A2 group XV (PLA2G15) LDTP09088 12.47  LDD2058 
Phospholipase A2 group XV (PLA2G15) LDTP09088 12.47  LDD2058 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 23.75  LDD2058 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 23.75  LDD2058 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 13.09  LDD2058 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 13.09  LDD2058 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 11.39  LDD2058 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 11.39  LDD2058 
Proteasome subunit beta type-4 (PSMB4) LDTP03417 8.94  LDD2058 
Proteasome subunit beta type-4 (PSMB4) LDTP03417 8.94  LDD2058 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 7.67  LDD2058 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 7.67  LDD2058 
Protein O-GlcNAcase (OGA) LDTP00988 16.91  LDD2058 
Protein O-GlcNAcase (OGA) LDTP00988 16.91  LDD2058 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 9.32  LDD2058 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 9.32  LDD2058 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 8.75  LDD2058 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 8.75  LDD2058 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 10.70  LDD2058 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 10.70  LDD2058 
Ras-related protein Rab-24 (RAB24) LDTP10020 13.64  LDD2058 
Ras-related protein Rab-24 (RAB24) LDTP10020 13.64  LDD2058 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 15.03  LDD2058 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 15.03  LDD2058 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 18.90  LDD2058 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 18.90  LDD2058 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 7.94  LDD2058 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 7.94  LDD2058 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PPP2R1B) LDTP03523 7.11  LDD2058 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PPP2R1B) LDTP03523 7.11  LDD2058 
Serine/threonine-protein phosphatase CPPED1 (CPPED1) LDTP11107 6.82  LDD2058 
Serine/threonine-protein phosphatase CPPED1 (CPPED1) LDTP11107 6.82  LDD2058 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 21.41  LDD2058 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 21.41  LDD2058 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 25.46  LDD2058 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 25.46  LDD2058 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 9.51  LDD2058 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 9.51  LDD2058 
TLC domain-containing protein 1 (TLCD1) LDTP10182 17.88  LDD2058 
TLC domain-containing protein 1 (TLCD1) LDTP10182 17.88  LDD2058 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 20.53  LDD2058 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 20.53  LDD2058 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 7.94  LDD2058 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 7.94  LDD2058 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 8.69  LDD2058 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 8.69  LDD2058 
------------------------------------------------------------------------------------
⏷ Show the Full List of 188 Enzyme
134 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 10.70  LDD2058 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 10.70  LDD2058 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 8.51  LDD2058 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 8.51  LDD2058 
Amyloid-beta precursor protein (APP) LDTP02071 8.82  LDD2058 
Amyloid-beta precursor protein (APP) LDTP02071 8.82  LDD2058 
ATP synthase subunit a (MT-ATP6) LDTP01804 29.24  LDD2058 
ATP synthase subunit a (MT-ATP6) LDTP01804 29.24  LDD2058 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 18.90  LDD2058 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 18.90  LDD2058 
BRI3-binding protein (BRI3BP) LDTP15648 21.86  LDD2058 
BRI3-binding protein (BRI3BP) LDTP15648 21.86  LDD2058 
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (COX16) LDTP16163 6.77  LDD2058 
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (COX16) LDTP16163 6.77  LDD2058 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 8.06  LDD2058 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 8.06  LDD2058 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 14.32  LDD2058 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 14.32  LDD2058 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 21.86  LDD2058 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 21.86  LDD2058 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 7.06  LDD2058 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 7.06  LDD2058 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 14.93  LDD2058 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 14.93  LDD2058 
Integral membrane protein 2C (ITM2C) LDTP12451 11.08  LDD2058 
Integral membrane protein 2C (ITM2C) LDTP12451 11.08  LDD2058 
Intermembrane lipid transfer protein VPS13A (VPS13A) LDTP10769 8.75  LDD2058 
Intermembrane lipid transfer protein VPS13A (VPS13A) LDTP10769 8.75  LDD2058 
Lysosome membrane protein 2 (SCARB2) LDTP06034 18.25  LDD2058 
Lysosome membrane protein 2 (SCARB2) LDTP06034 18.25  LDD2058 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 13.09  LDD2058 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 13.09  LDD2058 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 7.73  LDD2058 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 7.73  LDD2058 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 13.27  LDD2058 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 13.27  LDD2058 
Metaxin-1 (MTX1) LDTP05900 12.91  LDD2058 
Metaxin-1 (MTX1) LDTP05900 12.91  LDD2058 
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) LDTP07439 6.77  LDD2058 
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) LDTP07439 6.77  LDD2058 
Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42) LDTP08279 7.73  LDD2058 
Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42) LDTP08279 7.73  LDD2058 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 12.55  LDD2058 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 12.55  LDD2058 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 8.94  LDD2058 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 8.94  LDD2058 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 49.87  LDD2058 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 49.87  LDD2058 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 99.73  LDD2058 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 99.73  LDD2058 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 7.31  LDD2058 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 7.31  LDD2058 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 10.27  LDD2058 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 10.27  LDD2058 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 7.11  LDD2058 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 7.11  LDD2058 
Mpv17-like protein 2 (MPV17L2) LDTP14952 14.62  LDD2058 
Mpv17-like protein 2 (MPV17L2) LDTP14952 14.62  LDD2058 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 8.28  LDD2058 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 8.28  LDD2058 
Nucleoporin NDC1 (NDC1) LDTP11213 7.89  LDD2058 
Nucleoporin NDC1 (NDC1) LDTP11213 7.89  LDD2058 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 8.57  LDD2058 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 8.57  LDD2058 
Protein ARV1 (ARV1) LDTP11812 15.67  LDD2058 
Protein ARV1 (ARV1) LDTP11812 15.67  LDD2058 
Protein GPR107 (GPR107) LDTP07236 13.93  LDD2058 
Protein GPR107 (GPR107) LDTP07236 13.93  LDD2058 
Protein GPR108 (GPR108) LDTP12383 25.28  LDD2058 
Protein GPR108 (GPR108) LDTP12383 25.28  LDD2058 
Protein spinster homolog 1 (SPNS1) LDTP11844 8.88  LDD2058 
Protein spinster homolog 1 (SPNS1) LDTP11844 8.88  LDD2058 
Protein tweety homolog 3 (TTYH3) LDTP11615 14.22  LDD2058 
Protein tweety homolog 3 (TTYH3) LDTP11615 14.22  LDD2058 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 10.48  LDD2058 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 10.48  LDD2058 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 9.13  LDD2058 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 9.13  LDD2058 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 9.19  LDD2058 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 9.19  LDD2058 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 12.82  LDD2058 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 12.82  LDD2058 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 11.55  LDD2058 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 11.55  LDD2058 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 17.39  LDD2058 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 17.39  LDD2058 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 19.84  LDD2058 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 19.84  LDD2058 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 6.87  LDD2058 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 6.87  LDD2058 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 14.62  LDD2058 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 14.62  LDD2058 
Stomatin (STOM) LDTP03380 8.00  LDD2058 
Stomatin (STOM) LDTP03380 8.00  LDD2058 
Surfeit locus protein 4 (SURF4) LDTP00592 17.75  LDD2058 
Surfeit locus protein 4 (SURF4) LDTP00592 17.75  LDD2058 
Syntaxin-6 (STX6) LDTP00857 7.06  LDD2058 
Syntaxin-6 (STX6) LDTP00857 7.06  LDD2058 
Tetraspanin-3 (TSPAN3) LDTP16813 11.16  LDD2058 
Tetraspanin-3 (TSPAN3) LDTP16813 11.16  LDD2058 
THO complex subunit 5 homolog (THOC5) LDTP05978 7.67  LDD2058 
THO complex subunit 5 homolog (THOC5) LDTP05978 7.67  LDD2058 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 16.11  LDD2058 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 16.11  LDD2058 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 18.77  LDD2058 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 18.77  LDD2058 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 7.21  LDD2058 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 7.21  LDD2058 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 9.65  LDD2058 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 9.65  LDD2058 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 33.36  LDD2058 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 33.36  LDD2058 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 14.83  LDD2058 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 14.83  LDD2058 
Transmembrane protein 126A (TMEM126A) LDTP15948 26.17  LDD2058 
Transmembrane protein 126A (TMEM126A) LDTP15948 26.17  LDD2058 
Transmembrane protein 160 (TMEM160) LDTP20002 11.16  LDD2058 
Transmembrane protein 160 (TMEM160) LDTP20002 11.16  LDD2058 
Transmembrane protein 199 (TMEM199) LDTP08881 17.75  LDD2058 
Transmembrane protein 199 (TMEM199) LDTP08881 17.75  LDD2058 
Transmembrane protein 87A (TMEM87A) LDTP15481 25.63  LDD2058 
Transmembrane protein 87A (TMEM87A) LDTP15481 25.63  LDD2058 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 7.46  LDD2058 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 7.46  LDD2058 
Vacuolar protein sorting-associated protein 29 (VPS29) LDTP13142 12.04  LDD2058 
Vacuolar protein sorting-associated protein 29 (VPS29) LDTP13142 12.04  LDD2058 
Vacuole membrane protein 1 (VMP1) LDTP10343 8.82  LDD2058 
Vacuole membrane protein 1 (VMP1) LDTP10343 8.82  LDD2058 
Vang-like protein 1 (VANGL1) LDTP09288 7.01  LDD2058 
Vang-like protein 1 (VANGL1) LDTP09288 7.01  LDD2058 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 28.64  LDD2058 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 28.64  LDD2058 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 25.63  LDD2058 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 25.63  LDD2058 
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⏷ Show the Full List of 134 Transporter and channel
2 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 7.84  LDD2058 
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 7.84  LDD2058 
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124 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Abnormal spindle-like microcephaly-associated protein (ASPM) LDTP08716 20.11  LDD2058 
Abnormal spindle-like microcephaly-associated protein (ASPM) LDTP08716 20.11  LDD2058 
Activating signal cointegrator 1 complex subunit 2 (ASCC2) LDTP11766 7.67  LDD2058 
Activating signal cointegrator 1 complex subunit 2 (ASCC2) LDTP11766 7.67  LDD2058 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 11.88  LDD2058 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 11.88  LDD2058 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 8.17  LDD2058 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 8.17  LDD2058 
BRISC and BRCA1-A complex member 2 (BABAM2) LDTP12788 6.92  LDD2058 
BRISC and BRCA1-A complex member 2 (BABAM2) LDTP12788 6.92  LDD2058 
Centrin-2 (CETN2) LDTP03926 7.89  LDD2058 
Centrin-2 (CETN2) LDTP03926 7.89  LDD2058 
Centrosomal protein 43 (CEP43) LDTP01652 10.70  LDD2058 
Centrosomal protein 43 (CEP43) LDTP01652 10.70  LDD2058 
Clustered mitochondria protein homolog (CLUH) LDTP14486 8.28  LDD2058 
Clustered mitochondria protein homolog (CLUH) LDTP14486 8.28  LDD2058 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 14.42  LDD2058 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 14.42  LDD2058 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 7.62  LDD2058 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 7.62  LDD2058 
Divergent protein kinase domain 2A (DIPK2A) LDTP09143 6.73  LDD2058 
Divergent protein kinase domain 2A (DIPK2A) LDTP09143 6.73  LDD2058 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 8.00  LDD2058 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 8.00  LDD2058 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 11.55  LDD2058 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 11.55  LDD2058 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 8.06  LDD2058 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 8.06  LDD2058 
Gamma-tubulin complex component 3 (TUBGCP3) LDTP10191 9.99  LDD2058 
Gamma-tubulin complex component 3 (TUBGCP3) LDTP10191 9.99  LDD2058 
Glycolipid transfer protein (GLTP) LDTP12891 6.82  LDD2058 
Glycolipid transfer protein (GLTP) LDTP12891 6.82  LDD2058 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 12.64  LDD2058 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 12.64  LDD2058 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 6.77  LDD2058 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 6.77  LDD2058 
HEAT repeat-containing protein 3 (HEATR3) LDTP15253 7.52  LDD2058 
HEAT repeat-containing protein 3 (HEATR3) LDTP15253 7.52  LDD2058 
Heme-binding protein 1 (HEBP1) LDTP16078 8.11  LDD2058 
Heme-binding protein 1 (HEBP1) LDTP16078 8.11  LDD2058 
Large proline-rich protein BAG6 (BAG6) LDTP04094 8.88  LDD2058 
Large proline-rich protein BAG6 (BAG6) LDTP04094 8.88  LDD2058 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 17.39  LDD2058 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 17.39  LDD2058 
Membralin (TMEM259) LDTP14939 13.45  LDD2058 
Membralin (TMEM259) LDTP14939 13.45  LDD2058 
Mitochondrial import receptor subunit TOM20 homolog (TOMM20) LDTP06373 6.87  LDD2058 
Mitochondrial import receptor subunit TOM20 homolog (TOMM20) LDTP06373 6.87  LDD2058 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 65.34  LDD2058 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 65.34  LDD2058 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 15.03  LDD2058 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 15.03  LDD2058 
Nucleobindin-2 (NUCB2) LDTP05160 37.27  LDD2058 
Nucleobindin-2 (NUCB2) LDTP05160 37.27  LDD2058 
Optic atrophy 3 protein (OPA3) LDTP16006 8.75  LDD2058 
Optic atrophy 3 protein (OPA3) LDTP16006 8.75  LDD2058 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 9.00  LDD2058 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 9.00  LDD2058 
Proteasome activator complex subunit 4 (PSME4) LDTP06250 6.77  LDD2058 
Proteasome activator complex subunit 4 (PSME4) LDTP06250 6.77  LDD2058 
Protein CEBPZOS (CEBPZOS) LDTP18883 22.01  LDD2058 
Protein CEBPZOS (CEBPZOS) LDTP18883 22.01  LDD2058 
Protein CutA (CUTA) LDTP01075 9.13  LDD2058 
Protein CutA (CUTA) LDTP01075 9.13  LDD2058 
Protein FAM114A2 (FAM114A2) LDTP16080 16.11  LDD2058 
Protein FAM114A2 (FAM114A2) LDTP16080 16.11  LDD2058 
Protein FAM136A (FAM136A) LDTP18132 6.68  LDD2058 
Protein FAM136A (FAM136A) LDTP18132 6.68  LDD2058 
Protein FAM162A (FAM162A) LDTP10056 13.45  LDD2058 
Protein FAM162A (FAM162A) LDTP10056 13.45  LDD2058 
Protein FAM177A1 (FAM177A1) LDTP15398 7.21  LDD2058 
Protein FAM177A1 (FAM177A1) LDTP15398 7.21  LDD2058 
Protein FAM3C (FAM3C) LDTP09773 9.38  LDD2058 
Protein FAM3C (FAM3C) LDTP09773 9.38  LDD2058 
Protein jagunal homolog 1 (JAGN1) LDTP08904 7.01  LDD2058 
Protein jagunal homolog 1 (JAGN1) LDTP08904 7.01  LDD2058 
Protein unc-119 homolog A (UNC119) LDTP05868 11.08  LDD2058 
Protein unc-119 homolog A (UNC119) LDTP05868 11.08  LDD2058 
Protein unc-119 homolog B (UNC119B) LDTP00105 15.67  LDD2058 
Protein unc-119 homolog B (UNC119B) LDTP00105 15.67  LDD2058 
Protein UXT (UXT) LDTP13125 8.51  LDD2058 
Protein UXT (UXT) LDTP13125 8.51  LDD2058 
Protein YIF1A (YIF1A) LDTP01494 6.96  LDD2058 
Protein YIF1A (YIF1A) LDTP01494 6.96  LDD2058 
Regulator of microtubule dynamics protein 3 (RMDN3) LDTP10849 8.57  LDD2058 
Regulator of microtubule dynamics protein 3 (RMDN3) LDTP10849 8.57  LDD2058 
Reticulocalbin-2 (RCN2) LDTP06097 7.36  LDD2058 
Reticulocalbin-2 (RCN2) LDTP06097 7.36  LDD2058 
Reticulon-3 (RTN3) LDTP01522 19.16  LDD2058 
Reticulon-3 (RTN3) LDTP01522 19.16  LDD2058 
Reticulon-4 (RTN4) LDTP12412 10.93  LDD2058 
Reticulon-4 (RTN4) LDTP12412 10.93  LDD2058 
RNA transcription, translation and transport factor protein (RTRAF) LDTP13782 6.77  LDD2058 
RNA transcription, translation and transport factor protein (RTRAF) LDTP13782 6.77  LDD2058 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 7.84  LDD2058 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 7.84  LDD2058 
Splicing factor 3B subunit 5 (SF3B5) LDTP11328 6.73  LDD2058 
Splicing factor 3B subunit 5 (SF3B5) LDTP11328 6.73  LDD2058 
Synaptogyrin-2 (SYNGR2) LDTP00859 10.13  LDD2058 
Synaptogyrin-2 (SYNGR2) LDTP00859 10.13  LDD2058 
Syntaxin-10 (STX10) LDTP00986 17.63  LDD2058 
Syntaxin-10 (STX10) LDTP00986 17.63  LDD2058 
Syntaxin-18 (STX18) LDTP13086 19.70  LDD2058 
Syntaxin-18 (STX18) LDTP13086 19.70  LDD2058 
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) LDTP14263 7.84  LDD2058 
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) LDTP14263 7.84  LDD2058 
Tetraspanin-6 (TSPAN6) LDTP14458 23.75  LDD2058 
Tetraspanin-6 (TSPAN6) LDTP14458 23.75  LDD2058 
Tetratricopeptide repeat protein 38 (TTC38) LDTP19372 8.51  LDD2058 
Tetratricopeptide repeat protein 38 (TTC38) LDTP19372 8.51  LDD2058 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 12.38  LDD2058 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 12.38  LDD2058 
TraB domain-containing protein (TRABD) LDTP19963 9.19  LDD2058 
TraB domain-containing protein (TRABD) LDTP19963 9.19  LDD2058 
Translation initiation factor eIF2B subunit beta (EIF2B2) LDTP04304 9.25  LDD2058 
Translation initiation factor eIF2B subunit beta (EIF2B2) LDTP04304 9.25  LDD2058 
U6 snRNA-associated Sm-like protein LSm5 (LSM5) LDTP14080 13.93  LDD2058 
U6 snRNA-associated Sm-like protein LSm5 (LSM5) LDTP14080 13.93  LDD2058 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 31.34  LDD2058 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 31.34  LDD2058 
UPF0729 protein C18orf32 (C18orf32) LDTP15599 13.00  LDD2058 
UPF0729 protein C18orf32 (C18orf32) LDTP15599 13.00  LDD2058 
WD repeat-containing protein 43 (WDR43) LDTP06305 9.45  LDD2058 
WD repeat-containing protein 43 (WDR43) LDTP06305 9.45  LDD2058 
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⏷ Show the Full List of 124 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD2058 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587