Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C215 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 13.0 | ||||
| LDTP12253 | Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) | 12.7 | ||||
| LDTP12020 | Histone-lysine N-methyltransferase SMYD3 (SMYD3) | 11.0 | ||||
| LDTP06648 | Lanosterol 14-alpha demethylase (CYP51A1) | 10.6 | ||||
| LDTP01039 | Protein-S-isoprenylcysteine O-methyltransferase (ICMT) | 8.2 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 7.4 | ||||
| LDTP05476 | 3-ketodihydrosphingosine reductase (KDSR) | 7.2 | ||||
| LDTP04542 | Thimet oligopeptidase (THOP1) | 7.1 | ||||
| LDTP04438 | Succinate-semialdehyde dehydrogenase, mitochondrial (ALDH5A1) | 7.0 | ||||
| LDTP05724 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) | 7.0 | ||||
| LDTP08017 | Endoplasmic reticulum metallopeptidase 1 (ERMP1) | 6.5 | ||||
| LDTP03842 | Squalene synthase (FDFT1) | 5.8 | ||||
| LDTP10188 | FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) | 5.5 | ||||
| LDTP01687 | Apoptosis-inducing factor 1, mitochondrial (AIFM1) | 5.0 | ||||
| LDTP00886 | Nardilysin (NRDC) | 5.0 | ||||
| LDTP13358 | Leucyl-cystinyl aminopeptidase (LNPEP) | 5.0 | ||||
| LDTP04285 | Proteasome subunit beta type-2 (PSMB2) | 4.9 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP07667 | Transmembrane protein 205 (TMEM205) | 99.7 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 10.4 | ||||
| LDTP17362 | Magnesium transporter NIPA3 (NIPAL1) | 9.3 | ||||
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 9.1 | ||||
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 8.8 | ||||
| LDTP00865 | Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) | 8.2 | ||||
| LDTP10958 | Sigma non-opioid intracellular receptor 1 (SIGMAR1) | 7.9 | ||||
| LDTP11136 | Sugar transporter SWEET1 (SLC50A1) | 7.2 | ||||
| LDTP07236 | Protein GPR107 (GPR107) | 6.7 | ||||
| LDTP09547 | Scavenger receptor class B member 1 (SCARB1) | 6.5 | ||||
| LDTP15648 | BRI3-binding protein (BRI3BP) | 6.3 | ||||
| LDTP03061 | Cation-dependent mannose-6-phosphate receptor (M6PR) | 5.1 | ||||
| LDTP08881 | Transmembrane protein 199 (TMEM199) | 5.1 | ||||
| LDTP00541 | NPC intracellular cholesterol transporter 1 (NPC1) | 5.0 | ||||
| LDTP01671 | STARD3 N-terminal-like protein (STARD3NL) | 5.0 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP05868 | Protein unc-119 homolog A (UNC119) | 22.3 | ||||
| LDTP04382 | Kinetochore-associated protein 1 (KNTC1) | 16.0 | ||||
| LDTP15623 | Neuferricin (CYB5D2) | 13.2 | ||||
| LDTP04094 | Large proline-rich protein BAG6 (BAG6) | 13.1 | ||||
| LDTP11533 | Oxysterol-binding protein-related protein 6 (OSBPL6) | 11.9 | ||||
| LDTP11978 | HAUS augmin-like complex subunit 4 (HAUS4) | 9.9 | ||||
| LDTP00105 | Protein unc-119 homolog B (UNC119B) | 8.8 | ||||
| LDTP08130 | Rab9 effector protein with kelch motifs (RABEPK) | 6.1 | ||||
| LDTP19963 | TraB domain-containing protein (TRABD) | 6.0 | ||||
| LDTP14486 | Clustered mitochondria protein homolog (CLUH) | 5.9 | ||||
| LDTP13114 | C-type mannose receptor 2 (MRC2) | 5.7 | ||||