Details of the Probe

General Information of Probe

Probe ID
LDPC0328
Probe Name
C072
Synonyms
Z4225926149
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 320.4
Lipid-water partition coefficient (xlogp) 2.7
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C19H20N4O
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-2-(4-pyrrol-1-ylphenyl)acetamide
Canonical SMILES
C#CCCC1(N=N1)CCNC(=O)CC2=CC=C(C=C2)N3C=CC=C3
InChI
InChI=1S/C19H20N4O/c1-2-3-10-19(21-22-19)11-12-20-18(24)15-16-6-8-17(9-7-16)23-13-4-5-14-23/h1,4-9,13-14H,3,10-12,15H2,(H,20,24)
InChIKey
KMGMKALODGTZRZ-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

168 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 19.84  LDD1768 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 19.84  LDD1768 
Acid ceramidase (ASAH1) LDTP05905 11.47  LDD1768 
Acid ceramidase (ASAH1) LDTP05905 11.47  LDD1768 
Activin receptor type-1B (ACVR1B) LDTP03822 8.57  LDD1768 
Activin receptor type-1B (ACVR1B) LDTP03822 8.57  LDD1768 
ADP-dependent glucokinase (ADPGK) LDTP11127 13.09  LDD1768 
ADP-dependent glucokinase (ADPGK) LDTP11127 13.09  LDD1768 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 16.80  LDD1768 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 16.80  LDD1768 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 11.55  LDD1768 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 11.55  LDD1768 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 11.47  LDD1768 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 11.47  LDD1768 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 13.83  LDD1768 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 13.83  LDD1768 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 7.31  LDD1768 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 7.31  LDD1768 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 10.34  LDD1768 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 10.34  LDD1768 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 7.57  LDD1768 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 7.57  LDD1768 
Ceramide glucosyltransferase (UGCG) LDTP06617 8.57  LDD1768 
Ceramide glucosyltransferase (UGCG) LDTP06617 8.57  LDD1768 
Ceramide synthase 2 (CERS2) LDTP10329 8.06  LDD1768 
Ceramide synthase 2 (CERS2) LDTP10329 8.06  LDD1768 
Copper-transporting ATPase 2 (ATP7B) LDTP03779 8.28  LDD1768 
Copper-transporting ATPase 2 (ATP7B) LDTP03779 8.28  LDD1768 
Cysteine--tRNA ligase, cytoplasmic (CARS1) LDTP04263 22.01  LDD1768 
Cysteine--tRNA ligase, cytoplasmic (CARS1) LDTP04263 22.01  LDD1768 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 18.25  LDD1768 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 18.25  LDD1768 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 15.45  LDD1768 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 15.45  LDD1768 
Cytochrome b5 type B (CYB5B) LDTP00697 28.84  LDD1768 
Cytochrome b5 type B (CYB5B) LDTP00697 28.84  LDD1768 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 19.97  LDD1768 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 19.97  LDD1768 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 16.56  LDD1768 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 16.56  LDD1768 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 7.46  LDD1768 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 7.46  LDD1768 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 9.71  LDD1768 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 9.71  LDD1768 
Delta(14)-sterol reductase TM7SF2 (TM7SF2) LDTP01389 14.03  LDD1768 
Delta(14)-sterol reductase TM7SF2 (TM7SF2) LDTP01389 14.03  LDD1768 
Delta(24)-sterol reductase (DHCR24) LDTP06375 14.22  LDD1768 
Delta(24)-sterol reductase (DHCR24) LDTP06375 14.22  LDD1768 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 11.31  LDD1768 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 11.31  LDD1768 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 11.16  LDD1768 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 11.16  LDD1768 
Endoplasmic reticulum metallopeptidase 1 (ERMP1) LDTP08017 9.92  LDD1768 
Endoplasmic reticulum metallopeptidase 1 (ERMP1) LDTP08017 9.92  LDD1768 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 9.51  LDD1768 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 9.51  LDD1768 
Epoxide hydrolase 1 (EPHX1) LDTP02175 14.93  LDD1768 
Epoxide hydrolase 1 (EPHX1) LDTP02175 14.93  LDD1768 
Ferrochelatase, mitochondrial (FECH) LDTP03198 7.84  LDD1768 
Ferrochelatase, mitochondrial (FECH) LDTP03198 7.84  LDD1768 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 7.31  LDD1768 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 7.31  LDD1768 
GPI ethanolamine phosphate transferase 2 (PIGG) LDTP06977 7.73  LDD1768 
GPI ethanolamine phosphate transferase 2 (PIGG) LDTP06977 7.73  LDD1768 
Heme oxygenase 1 (HMOX1) LDTP02359 13.09  LDD1768 
Heme oxygenase 1 (HMOX1) LDTP02359 13.09  LDD1768 
Heme oxygenase 2 (HMOX2) LDTP03540 23.26  LDD1768 
Heme oxygenase 2 (HMOX2) LDTP03540 23.26  LDD1768 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 10.48  LDD1768 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 10.48  LDD1768 
Inositol 1,4,5-trisphosphate receptor-interacting protein (ITPRIP) LDTP08532 7.89  LDD1768 
Inositol 1,4,5-trisphosphate receptor-interacting protein (ITPRIP) LDTP08532 7.89  LDD1768 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 21.86  LDD1768 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 21.86  LDD1768 
Lanosterol synthase (LSS) LDTP04183 7.67  LDD1768 
Lanosterol synthase (LSS) LDTP04183 7.67  LDD1768 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 28.44  LDD1768 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 28.44  LDD1768 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 24.42  LDD1768 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 24.42  LDD1768 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 7.78  LDD1768 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 7.78  LDD1768 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 9.85  LDD1768 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 9.85  LDD1768 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 13.27  LDD1768 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 13.27  LDD1768 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 9.25  LDD1768 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 9.25  LDD1768 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 12.55  LDD1768 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 12.55  LDD1768 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 13.83  LDD1768 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 13.83  LDD1768 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 7.52  LDD1768 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 7.52  LDD1768 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 9.78  LDD1768 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 9.78  LDD1768 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 10.85  LDD1768 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 10.85  LDD1768 
NAD-dependent protein deacetylase sirtuin-2 (SIRT2) LDTP08598 9.00  LDD1768 
NAD-dependent protein deacetylase sirtuin-2 (SIRT2) LDTP08598 9.00  LDD1768 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 12.21  LDD1768 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 12.21  LDD1768 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 16.68  LDD1768 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 16.68  LDD1768 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 7.41  LDD1768 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 7.41  LDD1768 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 11.79  LDD1768 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 11.79  LDD1768 
NADH-ubiquinone oxidoreductase chain 2 (MT-ND2) LDTP01983 16.80  LDD1768 
NADH-ubiquinone oxidoreductase chain 2 (MT-ND2) LDTP01983 16.80  LDD1768 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 14.52  LDD1768 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 14.52  LDD1768 
Palmitoyltransferase ZDHHC13 (ZDHHC13) LDTP08455 7.89  LDD1768 
Palmitoyltransferase ZDHHC13 (ZDHHC13) LDTP08455 7.89  LDD1768 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 7.41  LDD1768 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 7.41  LDD1768 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 7.46  LDD1768 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 7.46  LDD1768 
Phospholipase A2 group XV (PLA2G15) LDTP09088 15.67  LDD1768 
Phospholipase A2 group XV (PLA2G15) LDTP09088 15.67  LDD1768 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 7.21  LDD1768 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 7.21  LDD1768 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 13.83  LDD1768 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 13.83  LDD1768 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 7.21  LDD1768 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 7.21  LDD1768 
Prostaglandin reductase 3 (PTGR3) LDTP15422 13.55  LDD1768 
Prostaglandin reductase 3 (PTGR3) LDTP15422 13.55  LDD1768 
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 18.77  LDD1768 
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 18.77  LDD1768 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 11.08  LDD1768 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 11.08  LDD1768 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 7.21  LDD1768 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 7.21  LDD1768 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 36.50  LDD1768 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 36.50  LDD1768 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 11.00  LDD1768 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 11.00  LDD1768 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 10.56  LDD1768 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 10.56  LDD1768 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 14.62  LDD1768 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 14.62  LDD1768 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 18.38  LDD1768 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 18.38  LDD1768 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 7.41  LDD1768 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 7.41  LDD1768 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 8.57  LDD1768 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 8.57  LDD1768 
Sphingosine kinase 2 (SPHK2) LDTP12490 25.81  LDD1768 
Sphingosine kinase 2 (SPHK2) LDTP12490 25.81  LDD1768 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 9.00  LDD1768 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 9.00  LDD1768 
Squalene synthase (FDFT1) LDTP03842 19.56  LDD1768 
Squalene synthase (FDFT1) LDTP03842 19.56  LDD1768 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 10.34  LDD1768 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 10.34  LDD1768 
TLC domain-containing protein 1 (TLCD1) LDTP10182 8.57  LDD1768 
TLC domain-containing protein 1 (TLCD1) LDTP10182 8.57  LDD1768 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 9.13  LDD1768 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 9.13  LDD1768 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 9.58  LDD1768 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 9.58  LDD1768 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 7.31  LDD1768 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 7.31  LDD1768 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 22.94  LDD1768 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 22.94  LDD1768 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 9.00  LDD1768 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 9.00  LDD1768 
------------------------------------------------------------------------------------
⏷ Show the Full List of 168 Enzyme
124 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 10.63  LDD1768 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 10.63  LDD1768 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 21.41  LDD1768 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 21.41  LDD1768 
BOS complex subunit NCLN (NCLN) LDTP10036 12.04  LDD1768 
BOS complex subunit NCLN (NCLN) LDTP10036 12.04  LDD1768 
BRI3-binding protein (BRI3BP) LDTP15648 18.25  LDD1768 
BRI3-binding protein (BRI3BP) LDTP15648 18.25  LDD1768 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 7.94  LDD1768 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 7.94  LDD1768 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 45.89  LDD1768 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 45.89  LDD1768 
Derlin-1 (DERL1) LDTP11245 11.08  LDD1768 
Derlin-1 (DERL1) LDTP11245 11.08  LDD1768 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 17.39  LDD1768 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 17.39  LDD1768 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 27.67  LDD1768 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 27.67  LDD1768 
Hippocampus abundant transcript-like protein 1 (MFSD14B) LDTP07063 8.22  LDD1768 
Hippocampus abundant transcript-like protein 1 (MFSD14B) LDTP07063 8.22  LDD1768 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 8.11  LDD1768 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 8.11  LDD1768 
Lysosome membrane protein 2 (SCARB2) LDTP06034 34.06  LDD1768 
Lysosome membrane protein 2 (SCARB2) LDTP06034 34.06  LDD1768 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 11.39  LDD1768 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 11.39  LDD1768 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 9.71  LDD1768 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 9.71  LDD1768 
Metaxin-1 (MTX1) LDTP05900 13.55  LDD1768 
Metaxin-1 (MTX1) LDTP05900 13.55  LDD1768 
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) LDTP07439 7.36  LDD1768 
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) LDTP07439 7.36  LDD1768 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 12.64  LDD1768 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 12.64  LDD1768 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 8.63  LDD1768 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 8.63  LDD1768 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 9.71  LDD1768 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 9.71  LDD1768 
Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42) LDTP08279 8.51  LDD1768 
Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42) LDTP08279 8.51  LDD1768 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 9.78  LDD1768 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 9.78  LDD1768 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 7.62  LDD1768 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 7.62  LDD1768 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 28.64  LDD1768 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 28.64  LDD1768 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 32.90  LDD1768 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 32.90  LDD1768 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 7.52  LDD1768 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 7.52  LDD1768 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 15.14  LDD1768 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 15.14  LDD1768 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 8.51  LDD1768 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 8.51  LDD1768 
Mpv17-like protein 2 (MPV17L2) LDTP14952 15.45  LDD1768 
Mpv17-like protein 2 (MPV17L2) LDTP14952 15.45  LDD1768 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 8.11  LDD1768 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 8.11  LDD1768 
Nucleoporin NDC1 (NDC1) LDTP11213 10.78  LDD1768 
Nucleoporin NDC1 (NDC1) LDTP11213 10.78  LDD1768 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 10.78  LDD1768 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 10.78  LDD1768 
Prosaposin (PSAP) LDTP02215 10.63  LDD1768 
Prosaposin (PSAP) LDTP02215 10.63  LDD1768 
Protein GPR107 (GPR107) LDTP07236 12.21  LDD1768 
Protein GPR107 (GPR107) LDTP07236 12.21  LDD1768 
Protein GPR108 (GPR108) LDTP12383 10.70  LDD1768 
Protein GPR108 (GPR108) LDTP12383 10.70  LDD1768 
Protein tweety homolog 3 (TTYH3) LDTP11615 13.09  LDD1768 
Protein tweety homolog 3 (TTYH3) LDTP11615 13.09  LDD1768 
Protein wntless homolog (WLS) LDTP07156 12.82  LDD1768 
Protein wntless homolog (WLS) LDTP07156 12.82  LDD1768 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 10.48  LDD1768 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 10.48  LDD1768 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 7.52  LDD1768 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 7.52  LDD1768 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 18.64  LDD1768 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 18.64  LDD1768 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 12.91  LDD1768 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 12.91  LDD1768 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 18.38  LDD1768 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 18.38  LDD1768 
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) LDTP10731 11.00  LDD1768 
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) LDTP10731 11.00  LDD1768 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 10.41  LDD1768 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 10.41  LDD1768 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 12.04  LDD1768 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 12.04  LDD1768 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 7.26  LDD1768 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 7.26  LDD1768 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 13.64  LDD1768 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 13.64  LDD1768 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 15.35  LDD1768 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 15.35  LDD1768 
Stomatin (STOM) LDTP03380 9.45  LDD1768 
Stomatin (STOM) LDTP03380 9.45  LDD1768 
Tetraspanin-3 (TSPAN3) LDTP16813 17.03  LDD1768 
Tetraspanin-3 (TSPAN3) LDTP16813 17.03  LDD1768 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 21.41  LDD1768 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 21.41  LDD1768 
Translocator protein (TSPO) LDTP03546 9.45  LDD1768 
Translocator protein (TSPO) LDTP03546 9.45  LDD1768 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 16.22  LDD1768 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 16.22  LDD1768 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 12.04  LDD1768 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 12.04  LDD1768 
Transmembrane protein 126A (TMEM126A) LDTP15948 25.11  LDD1768 
Transmembrane protein 126A (TMEM126A) LDTP15948 25.11  LDD1768 
Transmembrane protein 160 (TMEM160) LDTP20002 14.42  LDD1768 
Transmembrane protein 160 (TMEM160) LDTP20002 14.42  LDD1768 
Transmembrane protein 199 (TMEM199) LDTP08881 17.88  LDD1768 
Transmembrane protein 199 (TMEM199) LDTP08881 17.88  LDD1768 
Transmembrane protein 205 (TMEM205) LDTP07667 7.21  LDD1768 
Transmembrane protein 205 (TMEM205) LDTP07667 7.21  LDD1768 
Transmembrane protein 230 (TMEM230) LDTP10065 8.40  LDD1768 
Transmembrane protein 230 (TMEM230) LDTP10065 8.40  LDD1768 
Transmembrane protein 87A (TMEM87A) LDTP15481 9.00  LDD1768 
Transmembrane protein 87A (TMEM87A) LDTP15481 9.00  LDD1768 
Vang-like protein 1 (VANGL1) LDTP09288 8.40  LDD1768 
Vang-like protein 1 (VANGL1) LDTP09288 8.40  LDD1768 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 25.99  LDD1768 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 25.99  LDD1768 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 24.93  LDD1768 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 24.93  LDD1768 
------------------------------------------------------------------------------------
⏷ Show the Full List of 124 Transporter and channel
2 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 7.78  LDD1768 
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 7.78  LDD1768 
------------------------------------------------------------------------------------
2 GPCR Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Membrane progestin receptor alpha (PAQR7) LDTP15303 44.94  LDD1768 
Membrane progestin receptor alpha (PAQR7) LDTP15303 44.94  LDD1768 
------------------------------------------------------------------------------------
78 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 8.57  LDD1768 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 8.57  LDD1768 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 8.88  LDD1768 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 8.88  LDD1768 
Apolipoprotein L2 (APOL2) LDTP11076 50.21  LDD1768 
Apolipoprotein L2 (APOL2) LDTP11076 50.21  LDD1768 
Clustered mitochondria protein homolog (CLUH) LDTP14486 7.94  LDD1768 
Clustered mitochondria protein homolog (CLUH) LDTP14486 7.94  LDD1768 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 13.00  LDD1768 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 13.00  LDD1768 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 10.85  LDD1768 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 10.85  LDD1768 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 16.11  LDD1768 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 16.11  LDD1768 
Galanin peptides (GAL) LDTP03175 17.15  LDD1768 
Galanin peptides (GAL) LDTP03175 17.15  LDD1768 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 12.82  LDD1768 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 12.82  LDD1768 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 10.93  LDD1768 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 10.93  LDD1768 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 12.82  LDD1768 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 12.82  LDD1768 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 14.42  LDD1768 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 14.42  LDD1768 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 29.24  LDD1768 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 29.24  LDD1768 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 16.22  LDD1768 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 16.22  LDD1768 
Negative elongation factor C/D (NELFCD) LDTP08594 25.46  LDD1768 
Negative elongation factor C/D (NELFCD) LDTP08594 25.46  LDD1768 
Nucleobindin-1 (NUCB1) LDTP05375 14.03  LDD1768 
Nucleobindin-1 (NUCB1) LDTP05375 14.03  LDD1768 
Nucleobindin-2 (NUCB2) LDTP05160 12.21  LDD1768 
Nucleobindin-2 (NUCB2) LDTP05160 12.21  LDD1768 
Nurim (NRM) LDTP08606 11.88  LDD1768 
Nurim (NRM) LDTP08606 11.88  LDD1768 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 8.46  LDD1768 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 8.46  LDD1768 
Protein CEBPZOS (CEBPZOS) LDTP18883 19.43  LDD1768 
Protein CEBPZOS (CEBPZOS) LDTP18883 19.43  LDD1768 
Protein FAM114A2 (FAM114A2) LDTP16080 8.46  LDD1768 
Protein FAM114A2 (FAM114A2) LDTP16080 8.46  LDD1768 
Protein FAM162A (FAM162A) LDTP10056 12.91  LDD1768 
Protein FAM162A (FAM162A) LDTP10056 12.91  LDD1768 
Protein jagunal homolog 1 (JAGN1) LDTP08904 10.27  LDD1768 
Protein jagunal homolog 1 (JAGN1) LDTP08904 10.27  LDD1768 
Protein SET (SET) LDTP05277 8.11  LDD1768 
Protein SET (SET) LDTP05277 8.11  LDD1768 
Protein unc-119 homolog A (UNC119) LDTP05868 27.86  LDD1768 
Protein unc-119 homolog A (UNC119) LDTP05868 27.86  LDD1768 
Protein YIF1A (YIF1A) LDTP01494 9.78  LDD1768 
Protein YIF1A (YIF1A) LDTP01494 9.78  LDD1768 
Protein YIF1B (YIF1B) LDTP06948 7.67  LDD1768 
Protein YIF1B (YIF1B) LDTP06948 7.67  LDD1768 
Reticulon-3 (RTN3) LDTP01522 17.63  LDD1768 
Reticulon-3 (RTN3) LDTP01522 17.63  LDD1768 
Reticulon-4 (RTN4) LDTP12412 10.06  LDD1768 
Reticulon-4 (RTN4) LDTP12412 10.06  LDD1768 
Synaptogyrin-2 (SYNGR2) LDTP00859 7.21  LDD1768 
Synaptogyrin-2 (SYNGR2) LDTP00859 7.21  LDD1768 
Syntaxin-10 (STX10) LDTP00986 8.51  LDD1768 
Syntaxin-10 (STX10) LDTP00986 8.51  LDD1768 
Syntaxin-18 (STX18) LDTP13086 11.79  LDD1768 
Syntaxin-18 (STX18) LDTP13086 11.79  LDD1768 
Tetraspanin-6 (TSPAN6) LDTP14458 8.57  LDD1768 
Tetraspanin-6 (TSPAN6) LDTP14458 8.57  LDD1768 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 12.64  LDD1768 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 12.64  LDD1768 
TraB domain-containing protein (TRABD) LDTP19963 8.06  LDD1768 
TraB domain-containing protein (TRABD) LDTP19963 8.06  LDD1768 
Transmembrane protein 209 (TMEM209) LDTP18272 7.73  LDD1768 
Transmembrane protein 209 (TMEM209) LDTP18272 7.73  LDD1768 
Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) LDTP15634 15.03  LDD1768 
Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) LDTP15634 15.03  LDD1768 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 27.10  LDD1768 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 27.10  LDD1768 
Vacuolar protein sorting-associated protein 18 homolog (VPS18) LDTP13019 7.52  LDD1768 
Vacuolar protein sorting-associated protein 18 homolog (VPS18) LDTP13019 7.52  LDD1768 
------------------------------------------------------------------------------------
⏷ Show the Full List of 78 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1768 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587