Details of the Probe

General Information of Probe

Probe ID
LDPC0517
Probe Name
C287
Synonyms
Z4282859674
Probe Type
PAL-AfBPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 350.29
Lipid-water partition coefficient (xlogp) 3
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C16H13F3N4O2
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-[2-(trifluoromethyl)-1,3-benzoxazol-4-yl]propanamide
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)NC2=C3C(=CC=C2)OC(=N3)C(F)(F)F
InChI
InChI=1S/C16H13F3N4O2/c1-2-3-8-15(22-23-15)9-7-12(24)20-10-5-4-6-11-13(10)21-14(25-11)16(17,18)19/h1,4-6H,3,7-9H2,(H,20,24)
InChIKey
RPKNQDLDXPFURX-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

136 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) LDTP12639 10.70  LDD1957 
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 12.82  LDD1957 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 24.25  LDD1957 
Abasic site processing protein HMCES (HMCES) LDTP10322 33.59  LDD1957 
Acid ceramidase (ASAH1) LDTP05905 37.79  LDD1957 
Adenosine deaminase (ADA) LDTP01803 51.63  LDD1957 
ADP-dependent glucokinase (ADPGK) LDTP11127 19.56  LDD1957 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 28.05  LDD1957 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 21.26  LDD1957 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 16.00  LDD1957 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 10.27  LDD1957 
Antigen peptide transporter 1 (TAP1) LDTP05408 10.78  LDD1957 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 9.19  LDD1957 
Atlastin-2 (ATL2) LDTP09251 11.39  LDD1957 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 10.20  LDD1957 
Atypical kinase COQ8A, mitochondrial (COQ8A) LDTP09285 11.47  LDD1957 
Beta-galactosidase (GLB1) LDTP02837 9.99  LDD1957 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 13.93  LDD1957 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 21.71  LDD1957 
Calcium-transporting ATPase type 2C member 1 (ATP2C1) LDTP05228 11.55  LDD1957 
Carbohydrate sulfotransferase 12 (CHST12) LDTP12494 10.13  LDD1957 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 26.17  LDD1957 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 11.47  LDD1957 
Catechol O-methyltransferase (COMT) LDTP03145 9.58  LDD1957 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 49.52  LDD1957 
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT) LDTP00416 8.94  LDD1957 
Ceramide synthase 2 (CERS2) LDTP10329 13.36  LDD1957 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 11.16  LDD1957 
Cystathionine gamma-lyase (CTH) LDTP03656 9.65  LDD1957 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 30.06  LDD1957 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 21.11  LDD1957 
Cytochrome b5 type B (CYB5B) LDTP00697 44.94  LDD1957 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 9.19  LDD1957 
DCN1-like protein 4 (DCUN1D4) LDTP09799 14.52  LDD1957 
Dehydrodolichyl diphosphate synthase complex subunit DHDDS (DHDDS) LDTP08177 10.48  LDD1957 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 8.82  LDD1957 
Delta(24)-sterol reductase (DHCR24) LDTP06375 13.74  LDD1957 
Deoxyhypusine hydroxylase (DOHH) LDTP11225 10.78  LDD1957 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 10.48  LDD1957 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 9.92  LDD1957 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 10.34  LDD1957 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 31.12  LDD1957 
E3 ubiquitin-protein ligase MARCHF5 (MARCHF5) LDTP12757 8.82  LDD1957 
E3 ubiquitin-protein ligase TRIM13 (TRIM13) LDTP01065 22.16  LDD1957 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 15.67  LDD1957 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 9.45  LDD1957 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 13.83  LDD1957 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 11.31  LDD1957 
Epoxide hydrolase 1 (EPHX1) LDTP02175 11.79  LDD1957 
Ethanolamine kinase 1 (ETNK1) LDTP12197 11.63  LDD1957 
Ethanolaminephosphotransferase 1 (SELENOI) LDTP11606 8.75  LDD1957 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 10.06  LDD1957 
Ferrochelatase, mitochondrial (FECH) LDTP03198 16.34  LDD1957 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 12.91  LDD1957 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 8.88  LDD1957 
Heme A synthase COX15 (COX15) LDTP07931 12.64  LDD1957 
Heme oxygenase 1 (HMOX1) LDTP02359 15.89  LDD1957 
Heme oxygenase 2 (HMOX2) LDTP03540 51.63  LDD1957 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 10.78  LDD1957 
Hexokinase-2 (HK2) LDTP04531 8.69  LDD1957 
Holocytochrome c-type synthase (HCCS) LDTP04581 10.34  LDD1957 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 20.11  LDD1957 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 20.39  LDD1957 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 33.13  LDD1957 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 9.45  LDD1957 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 16.56  LDD1957 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 10.34  LDD1957 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 18.38  LDD1957 
Lysosomal acid phosphatase (ACP2) LDTP02539 8.57  LDD1957 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 11.96  LDD1957 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 16.34  LDD1957 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 37.53  LDD1957 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 22.78  LDD1957 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 10.41  LDD1957 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 9.65  LDD1957 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 14.22  LDD1957 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 88.03  LDD1957 
NADH dehydrogenase 1 beta subcomplex subunit 6 (NDUFB6) LDTP01502 11.00  LDD1957 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 23.92  LDD1957 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 10.70  LDD1957 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 37.27  LDD1957 
NADPH--cytochrome P450 reductase (POR) LDTP02848 9.58  LDD1957 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 13.83  LDD1957 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 58.49  LDD1957 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 11.24  LDD1957 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 11.39  LDD1957 
Peroxisomal leader peptide-processing protease (TYSND1) LDTP06720 8.88  LDD1957 
Phenylalanine--tRNA ligase beta subunit (FARSB) LDTP12586 31.78  LDD1957 
Phosphatidate cytidylyltransferase 2 (CDS2) LDTP01649 13.09  LDD1957 
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (PTPMT1) LDTP09578 8.94  LDD1957 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 8.75  LDD1957 
Phosphatidylserine synthase 2 (PTDSS2) LDTP11284 10.93  LDD1957 
Phospholipase A2 group XV (PLA2G15) LDTP09088 9.92  LDD1957 
Plasma membrane calcium-transporting ATPase 1 (ATP2B1) LDTP03024 8.88  LDD1957 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 9.99  LDD1957 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 38.59  LDD1957 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 14.22  LDD1957 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 15.24  LDD1957 
Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) LDTP02679 10.13  LDD1957 
Prostaglandin reductase 1 (PTGR1) LDTP06227 9.51  LDD1957 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 12.04  LDD1957 
Protein arginine N-methyltransferase 9 (PRMT9) LDTP07525 16.68  LDD1957 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 9.06  LDD1957 
Protein O-GlcNAcase (OGA) LDTP00988 8.94  LDD1957 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 12.64  LDD1957 
Rab-like protein 3 (RABL3) LDTP06986 12.91  LDD1957 
Ras-related protein Rab-24 (RAB24) LDTP10020 11.47  LDD1957 
Ras-related protein Rab-5B (RAB5B) LDTP04893 10.63  LDD1957 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 16.45  LDD1957 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 14.03  LDD1957 
Ribosomal protein S6 kinase delta-1 (RPS6KC1) LDTP10796 9.45  LDD1957 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 11.88  LDD1957 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 10.85  LDD1957 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 11.31  LDD1957 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 14.22  LDD1957 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 15.14  LDD1957 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 11.31  LDD1957 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 8.63  LDD1957 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 14.12  LDD1957 
Squalene monooxygenase (SQLE) LDTP06142 8.94  LDD1957 
Succinate-semialdehyde dehydrogenase, mitochondrial (ALDH5A1) LDTP04438 12.21  LDD1957 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 10.70  LDD1957 
Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) LDTP07227 12.47  LDD1957 
Transmembrane protein 62 (TMEM62) LDTP19223 10.41  LDD1957 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 10.63  LDD1957 
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (TRMT61A) LDTP10320 10.20  LDD1957 
tRNA (uracil-5-)-methyltransferase homolog A (TRMT2A) LDTP08687 11.08  LDD1957 
UbiA prenyltransferase domain-containing protein 1 (UBIAD1) LDTP14189 9.38  LDD1957 
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) LDTP11867 9.58  LDD1957 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 13.93  LDD1957 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 8.69  LDD1957 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 12.21  LDD1957 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 10.56  LDD1957 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 21.56  LDD1957 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 10.63  LDD1957 
Xyloside xylosyltransferase 1 (XXYLT1) LDTP09053 9.99  LDD1957 
------------------------------------------------------------------------------------
⏷ Show the Full List of 136 Enzyme
109 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 19.70  LDD1957 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 10.27  LDD1957 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 25.46  LDD1957 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 13.00  LDD1957 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 8.75  LDD1957 
Anoctamin-6 (ANO6) LDTP06855 9.00  LDD1957 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 15.56  LDD1957 
ATP synthase subunit a (MT-ATP6) LDTP01804 30.27  LDD1957 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 42.81  LDD1957 
Bax inhibitor 1 (TMBIM6) LDTP04663 9.65  LDD1957 
BRI3-binding protein (BRI3BP) LDTP15648 39.67  LDD1957 
Chloride intracellular channel protein 4 (CLIC4) LDTP14222 9.58  LDD1957 
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (COX16) LDTP16163 43.71  LDD1957 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 11.08  LDD1957 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 15.89  LDD1957 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 11.88  LDD1957 
Derlin-1 (DERL1) LDTP11245 38.85  LDD1957 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 13.36  LDD1957 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 34.06  LDD1957 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 14.52  LDD1957 
Essential MCU regulator, mitochondrial (SMDT1) LDTP11927 19.03  LDD1957 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 20.11  LDD1957 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 9.00  LDD1957 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 19.43  LDD1957 
H(+)/Cl(-) exchange transporter 7 (CLCN7) LDTP04463 9.00  LDD1957 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 15.67  LDD1957 
Integral membrane protein 2B (ITM2B) LDTP13833 12.91  LDD1957 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 9.71  LDD1957 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 15.24  LDD1957 
Lysosomal-associated transmembrane protein 4A (LAPTM4A) LDTP06275 31.56  LDD1957 
Lysosome membrane protein 2 (SCARB2) LDTP06034 26.17  LDD1957 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 17.27  LDD1957 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 9.32  LDD1957 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 31.12  LDD1957 
Metaxin-1 (MTX1) LDTP05900 22.01  LDD1957 
Methylosome subunit pICln (CLNS1A) LDTP04597 15.14  LDD1957 
MICOS complex subunit MIC26 (APOO) LDTP11250 14.52  LDD1957 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 11.63  LDD1957 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 11.31  LDD1957 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 8.69  LDD1957 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 21.86  LDD1957 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 12.82  LDD1957 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 18.00  LDD1957 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 33.13  LDD1957 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 49.52  LDD1957 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 24.59  LDD1957 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 16.68  LDD1957 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 11.96  LDD1957 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 18.25  LDD1957 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 22.32  LDD1957 
Mpv17-like protein 2 (MPV17L2) LDTP14952 11.08  LDD1957 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 15.67  LDD1957 
Nucleoporin NDC1 (NDC1) LDTP11213 12.38  LDD1957 
Nucleoporin NUP35 (NUP35) LDTP09204 11.16  LDD1957 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 9.99  LDD1957 
Peroxisomal membrane protein 11A (PEX11A) LDTP01160 19.43  LDD1957 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 9.19  LDD1957 
Peroxisomal membrane protein PEX16 (PEX16) LDTP14181 15.56  LDD1957 
Peroxisomal membrane protein PMP34 (SLC25A17) LDTP00872 8.69  LDD1957 
Prosaposin (PSAP) LDTP02215 19.56  LDD1957 
Protein ARV1 (ARV1) LDTP11812 12.82  LDD1957 
Protein GPR107 (GPR107) LDTP07236 34.54  LDD1957 
Protein GPR108 (GPR108) LDTP12383 19.29  LDD1957 
Protein spinster homolog 1 (SPNS1) LDTP11844 33.82  LDD1957 
Protein tweety homolog 3 (TTYH3) LDTP11615 29.86  LDD1957 
Protein wntless homolog (WLS) LDTP07156 10.48  LDD1957 
Protein YIPF3 (YIPF3) LDTP11626 17.27  LDD1957 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 12.64  LDD1957 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 12.73  LDD1957 
Reticulon-1 (RTN1) LDTP06633 10.06  LDD1957 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 18.00  LDD1957 
Sideroflexin-4 (SFXN4) LDTP07531 18.25  LDD1957 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 14.03  LDD1957 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 15.14  LDD1957 
Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15) LDTP11826 9.78  LDD1957 
Solute carrier family 25 member 16 (SLC25A16) LDTP14636 16.34  LDD1957 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 18.90  LDD1957 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 9.38  LDD1957 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 13.45  LDD1957 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 9.32  LDD1957 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 18.38  LDD1957 
Stomatin (STOM) LDTP03380 9.78  LDD1957 
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (SDHC) LDTP10931 9.58  LDD1957 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 12.73  LDD1957 
Syntaxin-6 (STX6) LDTP00857 29.86  LDD1957 
Tetraspanin-10 (TSPAN10) LDTP15967 17.27  LDD1957 
Tetraspanin-3 (TSPAN3) LDTP16813 50.91  LDD1957 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 25.99  LDD1957 
Translocation protein SEC62 (SEC62) LDTP15838 9.06  LDD1957 
Translocator protein (TSPO) LDTP03546 8.75  LDD1957 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 41.64  LDD1957 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 12.21  LDD1957 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 16.00  LDD1957 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 40.79  LDD1957 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 23.43  LDD1957 
Transmembrane protein 126A (TMEM126A) LDTP15948 57.28  LDD1957 
Transmembrane protein 160 (TMEM160) LDTP20002 58.08  LDD1957 
Transmembrane protein 199 (TMEM199) LDTP08881 34.06  LDD1957 
Transmembrane protein 205 (TMEM205) LDTP07667 12.64  LDD1957 
Transmembrane protein 214 (TMEM214) LDTP07477 9.51  LDD1957 
Transmembrane protein 230 (TMEM230) LDTP10065 16.11  LDD1957 
Transmembrane protein 59 (TMEM59) LDTP11406 12.64  LDD1957 
Transmembrane protein 87A (TMEM87A) LDTP15481 30.27  LDD1957 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 23.75  LDD1957 
Vang-like protein 1 (VANGL1) LDTP09288 13.36  LDD1957 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 45.57  LDD1957 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 30.70  LDD1957 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 14.32  LDD1957 
Wolframin (WFS1) LDTP01380 11.16  LDD1957 
------------------------------------------------------------------------------------
⏷ Show the Full List of 109 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 14.93  LDD1957 
------------------------------------------------------------------------------------
2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 9.25  LDD1957 
Neuroplastin (NPTN) LDTP14205 10.41  LDD1957 
------------------------------------------------------------------------------------
100 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 8.88  LDD1957 
Angiomotin (AMOT) LDTP06868 8.57  LDD1957 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 16.34  LDD1957 
Apolipoprotein L2 (APOL2) LDTP11076 26.72  LDD1957 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 10.41  LDD1957 
Cell division cycle-associated protein 2 (CDCA2) LDTP07345 9.13  LDD1957 
Clustered mitochondria protein homolog (CLUH) LDTP14486 12.21  LDD1957 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 9.19  LDD1957 
Conserved oligomeric Golgi complex subunit 3 (COG3) LDTP10452 9.06  LDD1957 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 9.13  LDD1957 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 14.22  LDD1957 
Cytochrome c oxidase assembly protein COX11, mitochondrial (COX11) LDTP14277 9.85  LDD1957 
DNA polymerase epsilon subunit 3 (POLE3) LDTP12506 9.00  LDD1957 
DNA replication complex GINS protein PSF2 (GINS2) LDTP13802 8.75  LDD1957 
Dymeclin (DYM) LDTP08000 10.56  LDD1957 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 19.56  LDD1957 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 38.85  LDD1957 
Ganglioside GM2 activator (GM2A) LDTP02927 10.48  LDD1957 
Gem-associated protein 8 (GEMIN8) LDTP12746 9.51  LDD1957 
General transcription factor IIF subunit 1 (GTF2F1) LDTP03729 13.64  LDD1957 
Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) LDTP00729 15.35  LDD1957 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 10.93  LDD1957 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 9.06  LDD1957 
Golgi SNAP receptor complex member 2 (GOSR2) LDTP00397 9.06  LDD1957 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 10.06  LDD1957 
Heme-binding protein 1 (HEBP1) LDTP16078 15.35  LDD1957 
HIG1 domain family member 1A, mitochondrial (HIGD1A) LDTP13797 11.47  LDD1957 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 12.91  LDD1957 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 9.71  LDD1957 
Large proline-rich protein BAG6 (BAG6) LDTP04094 13.09  LDD1957 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 10.20  LDD1957 
Large ribosomal subunit protein uL13m (MRPL13) LDTP15915 9.13  LDD1957 
Lipase maturation factor 2 (LMF2) LDTP15887 11.71  LDD1957 
Lipid droplet assembly factor 1 (LDAF1) LDTP10116 22.94  LDD1957 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 13.18  LDD1957 
Matrix-remodeling-associated protein 7 (MXRA7) LDTP17003 17.03  LDD1957 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 26.91  LDD1957 
Mitochondrial calcium uniporter regulator 1 (MCUR1) LDTP10093 8.63  LDD1957 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 16.22  LDD1957 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 29.45  LDD1957 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 27.86  LDD1957 
Mitochondrial import receptor subunit TOM7 homolog (TOMM7) LDTP12982 20.53  LDD1957 
Myosin light chain 6B (MYL6B) LDTP02736 8.75  LDD1957 
NLR family member X1 (NLRX1) LDTP08248 9.99  LDD1957 
Nucleobindin-1 (NUCB1) LDTP05375 10.34  LDD1957 
Nucleobindin-2 (NUCB2) LDTP05160 37.79  LDD1957 
Nucleolar protein 9 (NOP9) LDTP15283 10.93  LDD1957 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 11.08  LDD1957 
Nurim (NRM) LDTP08606 14.62  LDD1957 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 9.00  LDD1957 
Optic atrophy 3 protein (OPA3) LDTP16006 79.34  LDD1957 
p53 and DNA damage-regulated protein 1 (PDRG1) LDTP16099 12.91  LDD1957 
Peroxisomal membrane protein 11C (PEX11G) LDTP10381 10.20  LDD1957 
Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) LDTP11906 9.38  LDD1957 
Protein CEBPZOS (CEBPZOS) LDTP18883 14.72  LDD1957 
Protein FAM114A2 (FAM114A2) LDTP16080 25.81  LDD1957 
Protein FAM162A (FAM162A) LDTP10056 23.10  LDD1957 
Protein FAM3C (FAM3C) LDTP09773 9.38  LDD1957 
Protein jagunal homolog 1 (JAGN1) LDTP08904 11.00  LDD1957 
Protein LYRIC (MTDH) LDTP08224 19.16  LDD1957 
Protein unc-119 homolog B (UNC119B) LDTP00105 18.77  LDD1957 
Protein YIF1A (YIF1A) LDTP01494 8.75  LDD1957 
Protein YIF1B (YIF1B) LDTP06948 16.91  LDD1957 
Receptor expression-enhancing protein 2 (REEP2) LDTP11113 8.63  LDD1957 
Reticulon-2 (RTN2) LDTP01167 15.03  LDD1957 
Reticulon-3 (RTN3) LDTP01522 45.57  LDD1957 
Reticulon-4 (RTN4) LDTP12412 17.27  LDD1957 
Retinol-binding protein 1 (RBP1) LDTP02345 11.24  LDD1957 
RNA-binding protein with multiple splicing (RBPMS) LDTP09970 9.99  LDD1957 
RUS family member 1 (RUSF1) LDTP10357 18.00  LDD1957 
Sec1 family domain-containing protein 2 (SCFD2) LDTP18079 11.63  LDD1957 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 17.39  LDD1957 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 11.96  LDD1957 
Striatin (STRN) LDTP00875 14.72  LDD1957 
Synaptogyrin-2 (SYNGR2) LDTP00859 13.55  LDD1957 
Syntaxin-10 (STX10) LDTP00986 39.12  LDD1957 
Syntaxin-18 (STX18) LDTP13086 20.39  LDD1957 
Testis-expressed protein 264 (TEX264) LDTP14259 9.58  LDD1957 
Tetraspanin-6 (TSPAN6) LDTP14458 30.27  LDD1957 
Thioredoxin domain-containing protein 15 (TXNDC15) LDTP10442 9.19  LDD1957 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 25.81  LDD1957 
TraB domain-containing protein (TRABD) LDTP19963 12.82  LDD1957 
Transducin beta-like protein 2 (TBL2) LDTP16285 11.31  LDD1957 
Transmembrane protein 209 (TMEM209) LDTP18272 9.38  LDD1957 
Trophoblast glycoprotein (TPBG) LDTP05960 9.19  LDD1957 
Tubulin beta chain (TUBB) LDTP02205 22.32  LDD1957 
Tubulin beta-2A chain (TUBB2A) LDTP05998 21.41  LDD1957 
Tubulin beta-2B chain (TUBB2B) LDTP11277 21.71  LDD1957 
Tubulin beta-3 chain (TUBB3) LDTP05904 14.42  LDD1957 
Tubulin beta-4A chain (TUBB4A) LDTP02037 17.51  LDD1957 
Tubulin beta-4B chain (TUBB4B) LDTP05076 21.41  LDD1957 
Tubulin beta-6 chain (TUBB6) LDTP11233 16.00  LDD1957 
Tudor and KH domain-containing protein (TDRKH) LDTP13922 10.93  LDD1957 
U6 snRNA-associated Sm-like protein LSm3 (LSM3) LDTP04979 11.55  LDD1957 
Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) LDTP15634 10.27  LDD1957 
Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) LDTP01163 10.41  LDD1957 
Uncharacterized protein KIAA2013 (KIAA2013) LDTP17652 8.63  LDD1957 
UPF0449 protein C19orf25 (C19orf25) LDTP13214 18.38  LDD1957 
UPF0729 protein C18orf32 (C18orf32) LDTP15599 23.26  LDD1957 
Vang-like protein 2 (VANGL2) LDTP13560 18.51  LDD1957 
------------------------------------------------------------------------------------
⏷ Show the Full List of 100 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1957 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587