Details of the Probe-central Interaction Altas
General Information of Experiment
Probe Name | DR-1 | Probe Info | ||||
---|---|---|---|---|---|---|
Probe concentration | 1 uM | |||||
Criteria | Quantification: Probe vs DMSO | |||||
Quantitative Method |
SILAC
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In Vivo Experiment Model | Model Type |
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Living cell | |||
Derived Tissue |
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Lymph node | ||||
Disease Model | Lung large cell carcinoma [ICD-11:2C25] | |||||
Model Name | Human lung large cell carcinoma cells (NCI-H1299) | |||||
Interaction Altas of This Experiment [1]
Enzyme
Target ID | Target Name | Binding Ratio | ||||
---|---|---|---|---|---|---|
LDTP02198 | Cathepsin D (CTSD) | 8.3 | ||||
LDTP00697 | Cytochrome b5 type B (CYB5B) | 7.5 | ||||
LDTP04992 | Ras-related protein Rab-11A (RAB11A) | 5.3 | ||||
LDTP04437 | Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) | 5.1 | ||||
LDTP09396 | Minor histocompatibility antigen H13 (HM13) | 4.9 | ||||
LDTP00428 | Tripeptidyl-peptidase 1 (TPP1) | 4.9 | ||||
LDTP02848 | NADPH--cytochrome P450 reductase (POR) | 3.5 | ||||
LDTP06270 | Signal peptidase complex subunit 2 (SPCS2) | 3.2 | ||||
LDTP03145 | Catechol O-methyltransferase (COMT) | 3.0 | ||||
LDTP01328 | CAAX prenyl protease 1 homolog (ZMPSTE24) | 2.5 | ||||
LDTP11874 | Thioredoxin-related transmembrane protein 1 (TMX1) | 2.4 | ||||
LDTP02860 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) | 2.3 | ||||
LDTP04892 | Ras-related protein Rab-2A (RAB2A) | 2.1 | ||||
LDTP11311 | Very long chain fatty acid elongase 1 (ELOVL1) | 2.0 | ||||
LDTP07591 | Neutral cholesterol ester hydrolase 1 (NCEH1) | 2.0 |
Transporter and channel
Target ID | Target Name | Binding Ratio | ||||
---|---|---|---|---|---|---|
LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 7.1 | ||||
LDTP03405 | Calnexin (CANX) | 5.1 | ||||
LDTP01745 | Putative lipid scramblase CLPTM1 (CLPTM1) | 4.4 | ||||
LDTP04071 | Voltage-dependent anion-selective channel protein 2 (VDAC2) | 4.2 | ||||
LDTP02122 | Integrin beta-1 (ITGB1) | 4.0 | ||||
LDTP05511 | Cytoskeleton-associated protein 4 (CKAP4) | 4.0 | ||||
LDTP18448 | Transmembrane 9 superfamily member 3 (TM9SF3) | 3.9 | ||||
LDTP14661 | Transmembrane 4 L6 family member 1 (TM4SF1) | 3.6 | ||||
LDTP07236 | Protein GPR107 (GPR107) | 3.4 | ||||
LDTP15838 | Translocation protein SEC62 (SEC62) | 2.8 | ||||
LDTP01060 | PRA1 family protein 2 (PRAF2) | 2.7 | ||||
LDTP13824 | Voltage-dependent anion-selective channel protein 3 (VDAC3) | 2.6 | ||||
LDTP00361 | Nuclear envelope integral membrane protein 1 (NEMP1) | 2.5 | ||||
LDTP04426 | B-cell receptor-associated protein 31 (BCAP31) | 2.4 | ||||
LDTP04187 | CD151 antigen (CD151) | 2.2 | ||||
LDTP10081 | Leucine-rich repeat-containing protein 59 (LRRC59) | 2.2 |
Other
Target ID | Target Name | Binding Ratio | ||||
---|---|---|---|---|---|---|
LDTP10924 | Prohibitin-2 (PHB2) | 7.8 | ||||
LDTP12412 | Reticulon-4 (RTN4) | 6.7 | ||||
LDTP10889 | Perilipin-2 (PLIN2) | 5.5 | ||||
LDTP16323 | Signal recognition particle receptor subunit beta (SRPRB) | 4.3 | ||||
LDTP12755 | OCIA domain-containing protein 1 (OCIAD1) | 4.2 | ||||
LDTP03342 | Integrin alpha-3 (ITGA3) | 4.2 | ||||
LDTP03968 | Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) | 4.1 | ||||
LDTP04356 | Emerin (EMD) | 4.1 | ||||
LDTP02124 | Keratin, type I cytoskeletal 18 (KRT18) | 3.4 | ||||
LDTP02125 | Keratin, type II cytoskeletal 8 (KRT8) | 3.2 | ||||
LDTP04041 | Melanoma-associated antigen 4 (MAGEA4) | 3.0 | ||||
LDTP06948 | Protein YIF1B (YIF1B) | 2.8 | ||||
LDTP01021 | Perilipin-3 (PLIN3) | 2.2 | ||||
LDTP10013 | Protein YIPF5 (YIPF5) | 2.0 |