Details of the Target

General Information of Target

Target ID LDTP00323
Target Name CCN family member 1 (CCN1)
Gene Name CCN1
Gene ID 3491
Synonyms
CYR61; GIG1; IGFBP10; CCN family member 1; Cellular communication network factor 1; Cysteine-rich angiogenic inducer 61; Insulin-like growth factor-binding protein 10; IBP-10; IGF-binding protein 10; IGFBP-10; Protein CYR61; Protein GIG1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL
NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ
CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG
KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS
KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY
AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP
HANEAAFPFYRLFNDIHKFRD
Target Type
Literature-reported
Target Bioclass
Other
Family
CCN family
Subcellular location
Secreted
Function
Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CCN1-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.
TTD ID
T56505
Uniprot ID
O00622
DrugMap ID
TTQ7W6D
Ensemble ID
ENST00000451137.7
HGNC ID
HGNC:2654

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 12 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
ONAyne
 Probe Info  		K262(0.87); K378(2.53)  LDD0274  [1]
STPyne
 Probe Info  		K203(8.33); K262(4.62); K281(7.79); K307(0.77)  LDD0277  [1]
OPA-S-S-alkyne
 Probe Info  		K378(1.08); K208(2.96); K203(2.96)  LDD3494  [2]
BTD
 Probe Info  		C337(1.02); C100(0.53)  LDD2089  [3]
Jackson_14
 Probe Info  		2.33  LDD0123  [4]
IPM
 Probe Info  		C303(5.61); C26(2.74); C78(2.60); C272(2.50)  LDD1701  [3]
Acrolein
 Probe Info  		C100(0.00); C337(0.00)  LDD0222  [5]
DBIA
 Probe Info  		C229(1.08); C239(1.08); C314(1.08); C317(0.98)  LDD0078  [6]
NAIA_4
 Probe Info  		N.A.  LDD2226  [7]
TFBX
 Probe Info  		N.A.  LDD0148  [8]
Methacrolein
 Probe Info  		N.A.  LDD0218  [5]
NAIA_5
 Probe Info  		N.A.  LDD2223  [7]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0539  3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile MDA-MB-231 C100(0.53)  LDD2132  [3]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C337(0.77); C70(0.61)  LDD2131  [3]
 LDCM0214  AC1 PaTu 8988t C229(2.54); C239(2.54); C355(1.37); C359(1.37)  LDD1093  [6]
 LDCM0215  AC10 PaTu 8988t C322(2.08); C314(1.68); C229(2.23); C239(2.23)  LDD1094  [6]
 LDCM0216  AC100 PaTu 8988t C100(1.11); C229(1.59); C239(1.59); C359(1.60)  LDD1095  [6]
 LDCM0217  AC101 PaTu 8988t C100(0.95); C229(1.14); C239(1.14); C359(1.48)  LDD1096  [6]
 LDCM0218  AC102 PaTu 8988t C100(1.13); C229(0.99); C239(0.99); C359(1.28)  LDD1097  [6]
 LDCM0219  AC103 PaTu 8988t C100(1.23); C229(1.36); C239(1.36); C359(1.45)  LDD1098  [6]
 LDCM0220  AC104 PaTu 8988t C100(0.93); C229(0.92); C239(0.92); C359(1.46)  LDD1099  [6]
 LDCM0221  AC105 PaTu 8988t C100(1.35); C229(1.17); C239(1.17); C359(1.37)  LDD1100  [6]
 LDCM0222  AC106 PaTu 8988t C100(1.66); C229(1.04); C239(1.04); C359(1.34)  LDD1101  [6]
 LDCM0223  AC107 PaTu 8988t C100(1.54); C229(0.76); C239(0.76); C359(1.71)  LDD1102  [6]
 LDCM0224  AC108 PaTu 8988t C100(1.54); C229(1.15); C239(1.15); C359(1.37)  LDD1103  [6]
 LDCM0225  AC109 PaTu 8988t C100(1.70); C229(1.09); C239(1.09); C359(1.49)  LDD1104  [6]
 LDCM0226  AC11 PaTu 8988t C322(2.23); C314(1.23); C229(1.85); C239(1.85)  LDD1105  [6]
 LDCM0227  AC110 PaTu 8988t C100(1.89); C229(1.80); C239(1.80); C359(1.76)  LDD1106  [6]
 LDCM0228  AC111 PaTu 8988t C100(1.67); C229(1.21); C239(1.21); C359(1.78)  LDD1107  [6]
 LDCM0229  AC112 PaTu 8988t C100(1.24); C229(1.38); C239(1.38); C359(1.24)  LDD1108  [6]
 LDCM0230  AC113 PaTu 8988t C50(1.14); C355(1.08); C359(0.96)  LDD1109  [6]
 LDCM0231  AC114 PaTu 8988t C50(1.15); C355(0.75); C359(1.02)  LDD1110  [6]
 LDCM0232  AC115 PaTu 8988t C50(1.45); C355(1.11); C359(1.16)  LDD1111  [6]
 LDCM0233  AC116 PaTu 8988t C50(1.24); C355(1.48); C359(1.21)  LDD1112  [6]
 LDCM0234  AC117 PaTu 8988t C50(1.38); C355(0.95); C359(1.10)  LDD1113  [6]
 LDCM0235  AC118 PaTu 8988t C50(1.24); C355(0.82); C359(1.17)  LDD1114  [6]
 LDCM0236  AC119 PaTu 8988t C50(1.29); C355(0.69); C359(0.88)  LDD1115  [6]
 LDCM0237  AC12 PaTu 8988t C322(1.12); C314(2.01); C229(1.60); C239(1.60)  LDD1116  [6]
 LDCM0238  AC120 PaTu 8988t C50(0.92); C355(0.61); C359(1.03)  LDD1117  [6]
 LDCM0239  AC121 PaTu 8988t C50(1.10); C355(0.89); C359(0.95)  LDD1118  [6]
 LDCM0240  AC122 PaTu 8988t C50(0.94); C355(1.34); C359(1.08)  LDD1119  [6]
 LDCM0241  AC123 PaTu 8988t C50(0.95); C355(0.69); C359(0.93)  LDD1120  [6]
 LDCM0242  AC124 PaTu 8988t C50(1.14); C355(0.86); C359(1.26)  LDD1121  [6]
 LDCM0243  AC125 PaTu 8988t C50(1.33); C355(1.10); C359(1.10)  LDD1122  [6]
 LDCM0244  AC126 PaTu 8988t C50(1.16); C355(0.90); C359(1.11)  LDD1123  [6]
 LDCM0245  AC127 PaTu 8988t C50(0.91); C355(0.92); C359(1.04)  LDD1124  [6]
 LDCM0246  AC128 PaTu 8988t C267(1.34); C272(1.34); C355(1.06); C359(1.14)  LDD1125  [6]
 LDCM0247  AC129 PaTu 8988t C267(1.29); C272(1.29); C355(1.09); C359(1.09)  LDD1126  [6]
 LDCM0249  AC130 PaTu 8988t C267(1.31); C272(1.31); C355(1.05); C359(1.17)  LDD1128  [6]
 LDCM0250  AC131 PaTu 8988t C267(1.13); C272(1.13); C355(1.39); C359(1.13)  LDD1129  [6]
 LDCM0251  AC132 PaTu 8988t C267(1.18); C272(1.18); C355(0.92); C359(0.94)  LDD1130  [6]
 LDCM0252  AC133 PaTu 8988t C267(1.45); C272(1.45); C355(1.00); C359(1.31)  LDD1131  [6]
 LDCM0253  AC134 PaTu 8988t C267(1.23); C272(1.23); C355(0.92); C359(1.50)  LDD1132  [6]
 LDCM0254  AC135 PaTu 8988t C267(1.32); C272(1.32); C355(1.13); C359(1.36)  LDD1133  [6]
 LDCM0255  AC136 PaTu 8988t C267(1.12); C272(1.12); C355(0.94); C359(1.14)  LDD1134  [6]
 LDCM0256  AC137 PaTu 8988t C267(1.09); C272(1.09); C355(1.09); C359(1.16)  LDD1135  [6]
 LDCM0257  AC138 PaTu 8988t C267(1.07); C272(1.07); C355(1.22); C359(1.10)  LDD1136  [6]
 LDCM0258  AC139 PaTu 8988t C267(1.26); C272(1.26); C355(0.88); C359(1.13)  LDD1137  [6]
 LDCM0259  AC14 PaTu 8988t C322(1.47); C314(1.23); C229(1.76); C239(1.76)  LDD1138  [6]
 LDCM0260  AC140 PaTu 8988t C267(1.02); C272(1.02); C355(0.88); C359(0.97)  LDD1139  [6]
 LDCM0261  AC141 PaTu 8988t C267(1.08); C272(1.08); C355(1.30); C359(1.40)  LDD1140  [6]
 LDCM0262  AC142 PaTu 8988t C267(1.26); C272(1.26); C355(1.49); C359(1.19)  LDD1141  [6]
 LDCM0263  AC143 PaTu 8988t C100(1.44); C314(1.27); C355(0.95); C359(0.95)  LDD1142  [6]
 LDCM0264  AC144 PaTu 8988t C100(1.72); C314(2.46); C355(1.46); C359(1.46)  LDD1143  [6]
 LDCM0265  AC145 PaTu 8988t C100(1.50); C314(1.80); C355(1.29); C359(1.29)  LDD1144  [6]
 LDCM0266  AC146 PaTu 8988t C100(1.98); C314(1.70); C355(1.11); C359(1.11)  LDD1145  [6]
 LDCM0267  AC147 PaTu 8988t C100(1.68); C314(1.24); C355(1.09); C359(1.09)  LDD1146  [6]
 LDCM0268  AC148 PaTu 8988t C100(2.42); C314(1.81); C355(1.25); C359(1.25)  LDD1147  [6]
 LDCM0269  AC149 PaTu 8988t C100(1.97); C314(1.83); C355(1.23); C359(1.23)  LDD1148  [6]
 LDCM0270  AC15 PaTu 8988t C322(1.52); C314(1.48); C229(1.58); C239(1.58)  LDD1149  [6]
 LDCM0271  AC150 PaTu 8988t C100(2.14); C314(1.70); C355(1.39); C359(1.39)  LDD1150  [6]
 LDCM0272  AC151 PaTu 8988t C100(3.50); C314(2.02); C355(1.40); C359(1.40)  LDD1151  [6]
 LDCM0273  AC152 PaTu 8988t C100(1.98); C314(1.64); C355(1.40); C359(1.40)  LDD1152  [6]
 LDCM0274  AC153 PaTu 8988t C100(2.45); C314(2.21); C355(1.31); C359(1.31)  LDD1153  [6]
 LDCM0621  AC154 PaTu 8988t C100(4.28); C314(1.63); C355(1.30); C359(1.30)  LDD2166  [6]
 LDCM0622  AC155 PaTu 8988t C100(2.54); C314(2.51); C355(1.41); C359(1.41)  LDD2167  [6]
 LDCM0623  AC156 PaTu 8988t C100(2.95); C314(3.09); C355(1.34); C359(1.34)  LDD2168  [6]
 LDCM0624  AC157 PaTu 8988t C100(2.10); C314(2.26); C355(1.10); C359(1.10)  LDD2169  [6]
 LDCM0276  AC17 PaTu 8988t C314(1.30); C50(0.88); C267(1.21); C272(1.21)  LDD1155  [6]
 LDCM0277  AC18 PaTu 8988t C314(1.28); C50(1.27); C267(1.36); C272(1.36)  LDD1156  [6]
 LDCM0278  AC19 PaTu 8988t C314(1.73); C50(0.93); C267(0.97); C272(0.97)  LDD1157  [6]
 LDCM0279  AC2 PaTu 8988t C229(1.94); C239(1.94); C355(1.27); C359(1.27)  LDD1158  [6]
 LDCM0280  AC20 PaTu 8988t C314(1.53); C50(1.18); C267(1.35); C272(1.35)  LDD1159  [6]
 LDCM0281  AC21 PaTu 8988t C314(1.22); C50(0.78); C267(1.06); C272(1.06)  LDD1160  [6]
 LDCM0282  AC22 PaTu 8988t C314(1.77); C50(1.12); C267(1.65); C272(1.65)  LDD1161  [6]
 LDCM0283  AC23 PaTu 8988t C314(2.16); C50(2.52); C267(2.02); C272(2.02)  LDD1162  [6]
 LDCM0284  AC24 PaTu 8988t C314(3.10); C50(1.53); C267(1.33); C272(1.33)  LDD1163  [6]
 LDCM0285  AC25 PaTu 8988t C322(1.22); C50(0.91); C267(0.79); C272(0.79)  LDD1164  [6]
 LDCM0286  AC26 PaTu 8988t C322(1.67); C50(1.01); C267(1.02); C272(1.02)  LDD1165  [6]
 LDCM0287  AC27 PaTu 8988t C322(1.94); C50(1.11); C267(0.95); C272(0.95)  LDD1166  [6]
 LDCM0288  AC28 PaTu 8988t C322(1.79); C50(1.15); C267(1.27); C272(1.27)  LDD1167  [6]
 LDCM0289  AC29 PaTu 8988t C322(1.18); C50(1.05); C267(1.00); C272(1.00)  LDD1168  [6]
 LDCM0290  AC3 PaTu 8988t C229(1.54); C239(1.54); C355(1.22); C359(1.22)  LDD1169  [6]
 LDCM0291  AC30 PaTu 8988t C322(1.28); C50(1.07); C267(1.13); C272(1.13)  LDD1170  [6]
 LDCM0292  AC31 PaTu 8988t C322(1.12); C50(0.85); C267(0.89); C272(0.89)  LDD1171  [6]
 LDCM0293  AC32 PaTu 8988t C322(0.90); C50(1.04); C267(0.96); C272(0.96)  LDD1172  [6]
 LDCM0294  AC33 PaTu 8988t C322(1.68); C50(1.08); C267(1.29); C272(1.29)  LDD1173  [6]
 LDCM0295  AC34 PaTu 8988t C322(1.22); C50(1.33); C267(0.83); C272(0.83)  LDD1174  [6]
 LDCM0296  AC35 PaTu 8988t C355(1.17); C359(1.17)  LDD1175  [6]
 LDCM0297  AC36 PaTu 8988t C355(1.45); C359(1.45)  LDD1176  [6]
 LDCM0298  AC37 PaTu 8988t C355(1.51); C359(1.51)  LDD1177  [6]
 LDCM0299  AC38 PaTu 8988t C355(1.83); C359(1.83)  LDD1178  [6]
 LDCM0300  AC39 PaTu 8988t C355(1.30); C359(1.30)  LDD1179  [6]
 LDCM0301  AC4 PaTu 8988t C229(1.82); C239(1.82); C355(1.22); C359(1.22)  LDD1180  [6]
 LDCM0302  AC40 PaTu 8988t C355(1.72); C359(1.72)  LDD1181  [6]
 LDCM0303  AC41 PaTu 8988t C355(1.34); C359(1.34)  LDD1182  [6]
 LDCM0304  AC42 PaTu 8988t C355(1.27); C359(1.27)  LDD1183  [6]
 LDCM0305  AC43 PaTu 8988t C355(1.37); C359(1.37)  LDD1184  [6]
 LDCM0306  AC44 PaTu 8988t C355(1.58); C359(1.58)  LDD1185  [6]
 LDCM0307  AC45 PaTu 8988t C355(1.38); C359(1.38)  LDD1186  [6]
 LDCM0308  AC46 PaTu 8988t C317(1.77); C314(1.77); C229(1.58); C239(1.58)  LDD1187  [6]
 LDCM0309  AC47 PaTu 8988t C317(1.51); C314(1.51); C229(1.39); C239(1.39)  LDD1188  [6]
 LDCM0310  AC48 PaTu 8988t C317(2.32); C314(2.32); C229(1.64); C239(1.64)  LDD1189  [6]
 LDCM0311  AC49 PaTu 8988t C317(1.46); C314(1.46); C229(1.77); C239(1.77)  LDD1190  [6]
 LDCM0312  AC5 PaTu 8988t C229(2.14); C239(2.14); C355(1.12); C359(1.12)  LDD1191  [6]
 LDCM0313  AC50 PaTu 8988t C317(1.18); C314(1.18); C229(1.66); C239(1.66)  LDD1192  [6]
 LDCM0314  AC51 PaTu 8988t C317(1.13); C314(1.13); C229(0.59); C239(0.59)  LDD1193  [6]
 LDCM0315  AC52 PaTu 8988t C317(1.89); C314(1.89); C229(1.54); C239(1.54)  LDD1194  [6]
 LDCM0316  AC53 PaTu 8988t C317(2.36); C314(2.36); C229(2.73); C239(2.73)  LDD1195  [6]
 LDCM0317  AC54 PaTu 8988t C317(1.86); C314(1.86); C229(1.84); C239(1.84)  LDD1196  [6]
 LDCM0318  AC55 PaTu 8988t C317(1.95); C314(1.95); C229(1.44); C239(1.44)  LDD1197  [6]
 LDCM0319  AC56 PaTu 8988t C317(1.27); C314(1.27); C229(2.47); C239(2.47)  LDD1198  [6]
 LDCM0320  AC57 PaTu 8988t C267(0.95); C272(0.95); C355(1.38); C359(1.38)  LDD1199  [6]
 LDCM0321  AC58 PaTu 8988t C267(1.02); C272(1.02); C355(0.99); C359(0.99)  LDD1200  [6]
 LDCM0322  AC59 PaTu 8988t C267(1.22); C272(1.22); C355(1.16); C359(1.16)  LDD1201  [6]
 LDCM0323  AC6 PaTu 8988t C322(1.32); C314(1.14); C229(1.40); C239(1.40)  LDD1202  [6]
 LDCM0324  AC60 PaTu 8988t C267(0.88); C272(0.88); C355(1.43); C359(1.43)  LDD1203  [6]
 LDCM0325  AC61 PaTu 8988t C267(1.23); C272(1.23); C355(1.53); C359(1.53)  LDD1204  [6]
 LDCM0326  AC62 PaTu 8988t C267(1.19); C272(1.19); C355(1.37); C359(1.37)  LDD1205  [6]
 LDCM0327  AC63 PaTu 8988t C267(1.12); C272(1.12); C355(1.17); C359(1.17)  LDD1206  [6]
 LDCM0328  AC64 PaTu 8988t C267(1.21); C272(1.21); C355(1.33); C359(1.33)  LDD1207  [6]
 LDCM0329  AC65 PaTu 8988t C267(1.12); C272(1.12); C355(1.56); C359(1.56)  LDD1208  [6]
 LDCM0330  AC66 PaTu 8988t C267(0.95); C272(0.95); C355(1.28); C359(1.28)  LDD1209  [6]
 LDCM0331  AC67 PaTu 8988t C267(1.15); C272(1.15); C355(1.63); C359(1.63)  LDD1210  [6]
 LDCM0332  AC68 PaTu 8988t C229(0.75); C239(0.75); C267(1.77); C272(1.77)  LDD1211  [6]
 LDCM0333  AC69 PaTu 8988t C229(0.85); C239(0.85); C267(1.65); C272(1.65)  LDD1212  [6]
 LDCM0334  AC7 PaTu 8988t C322(1.01); C314(1.41); C229(1.14); C239(1.14)  LDD1213  [6]
 LDCM0335  AC70 PaTu 8988t C229(0.77); C239(0.77); C267(1.32); C272(1.32)  LDD1214  [6]
 LDCM0336  AC71 PaTu 8988t C229(0.98); C239(0.98); C267(1.18); C272(1.18)  LDD1215  [6]
 LDCM0337  AC72 PaTu 8988t C229(0.68); C239(0.68); C267(1.56); C272(1.56)  LDD1216  [6]
 LDCM0338  AC73 PaTu 8988t C229(0.90); C239(0.90); C267(1.23); C272(1.23)  LDD1217  [6]
 LDCM0339  AC74 PaTu 8988t C229(0.88); C239(0.88); C267(1.67); C272(1.67)  LDD1218  [6]
 LDCM0340  AC75 PaTu 8988t C229(0.91); C239(0.91); C267(1.20); C272(1.20)  LDD1219  [6]
 LDCM0341  AC76 PaTu 8988t C229(0.89); C239(0.89); C267(1.23); C272(1.23)  LDD1220  [6]
 LDCM0342  AC77 PaTu 8988t C229(0.75); C239(0.75); C267(1.27); C272(1.27)  LDD1221  [6]
 LDCM0343  AC78 PaTu 8988t C229(0.75); C239(0.75); C267(1.58); C272(1.58)  LDD1222  [6]
 LDCM0344  AC79 PaTu 8988t C229(0.62); C239(0.62); C267(1.73); C272(1.73)  LDD1223  [6]
 LDCM0345  AC8 PaTu 8988t C322(1.00); C314(1.70); C229(1.47); C239(1.47)  LDD1224  [6]
 LDCM0346  AC80 PaTu 8988t C229(0.67); C239(0.67); C267(1.64); C272(1.64)  LDD1225  [6]
 LDCM0347  AC81 PaTu 8988t C229(1.23); C239(1.23); C267(1.42); C272(1.42)  LDD1226  [6]
 LDCM0348  AC82 PaTu 8988t C229(0.72); C239(0.72); C267(1.48); C272(1.48)  LDD1227  [6]
 LDCM0349  AC83 PaTu 8988t C359(1.32)  LDD1228  [6]
 LDCM0350  AC84 PaTu 8988t C359(0.87)  LDD1229  [6]
 LDCM0351  AC85 PaTu 8988t C359(1.31)  LDD1230  [6]
 LDCM0352  AC86 PaTu 8988t C359(1.39)  LDD1231  [6]
 LDCM0353  AC87 PaTu 8988t C359(0.98)  LDD1232  [6]
 LDCM0354  AC88 PaTu 8988t C359(1.08)  LDD1233  [6]
 LDCM0355  AC89 PaTu 8988t C359(0.98)  LDD1234  [6]
 LDCM0357  AC90 PaTu 8988t C359(0.94)  LDD1236  [6]
 LDCM0358  AC91 PaTu 8988t C359(1.12)  LDD1237  [6]
 LDCM0359  AC92 PaTu 8988t C359(0.99)  LDD1238  [6]
 LDCM0360  AC93 PaTu 8988t C359(0.86)  LDD1239  [6]
 LDCM0361  AC94 PaTu 8988t C359(1.21)  LDD1240  [6]
 LDCM0362  AC95 PaTu 8988t C359(0.95)  LDD1241  [6]
 LDCM0363  AC96 PaTu 8988t C359(1.06)  LDD1242  [6]
 LDCM0364  AC97 PaTu 8988t C359(1.09)  LDD1243  [6]
 LDCM0365  AC98 PaTu 8988t C100(3.03); C229(1.32); C239(1.32); C359(1.16)  LDD1244  [6]
 LDCM0366  AC99 PaTu 8988t C100(1.52); C229(0.92); C239(0.92); C359(1.28)  LDD1245  [6]
 LDCM0545  Acetamide MDA-MB-231 C337(0.89)  LDD2138  [3]
 LDCM0520  AKOS000195272 MDA-MB-231 C337(1.10); C100(1.01)  LDD2113  [3]
 LDCM0248  AKOS034007472 PaTu 8988t C322(1.58); C314(1.81); C229(2.01); C239(2.01)  LDD1127  [6]
 LDCM0356  AKOS034007680 PaTu 8988t C322(1.78); C314(1.05); C229(1.32); C239(1.32)  LDD1235  [6]
 LDCM0275  AKOS034007705 PaTu 8988t C322(1.62); C314(1.54); C229(2.00); C239(2.00)  LDD1154  [6]
 LDCM0020  ARS-1620 HCC44 C229(1.08); C239(1.08); C314(1.08); C317(0.98)  LDD0078  [6]
 LDCM0498  BS-3668 MDA-MB-231 C100(0.46)  LDD2091  [3]
 LDCM0108  Chloroacetamide HeLa C100(0.00); C337(0.00)  LDD0222  [5]
 LDCM0367  CL1 PaTu 8988t C50(0.91); C267(0.97); C272(0.97); C355(0.78)  LDD1246  [6]
 LDCM0368  CL10 PaTu 8988t C50(1.17); C267(0.77); C272(0.77); C355(0.82)  LDD1247  [6]
 LDCM0369  CL100 PaTu 8988t C229(1.73); C239(1.73); C355(1.22); C359(1.22)  LDD1248  [6]
 LDCM0370  CL101 PaTu 8988t C322(1.50); C314(1.23); C229(1.35); C239(1.35)  LDD1249  [6]
 LDCM0371  CL102 PaTu 8988t C322(1.03); C314(1.06); C229(1.62); C239(1.62)  LDD1250  [6]
 LDCM0372  CL103 PaTu 8988t C322(1.40); C314(1.20); C229(1.59); C239(1.59)  LDD1251  [6]
 LDCM0373  CL104 PaTu 8988t C322(1.39); C314(0.86); C229(1.83); C239(1.83)  LDD1252  [6]
 LDCM0374  CL105 PaTu 8988t C314(1.18); C50(0.94); C267(1.19); C272(1.19)  LDD1253  [6]
 LDCM0375  CL106 PaTu 8988t C314(2.16); C50(0.92); C267(1.21); C272(1.21)  LDD1254  [6]
 LDCM0376  CL107 PaTu 8988t C314(1.63); C50(1.00); C267(1.18); C272(1.18)  LDD1255  [6]
 LDCM0377  CL108 PaTu 8988t C314(1.26); C50(1.07); C267(0.91); C272(0.91)  LDD1256  [6]
 LDCM0378  CL109 PaTu 8988t C314(1.82); C50(1.23); C267(1.38); C272(1.38)  LDD1257  [6]
 LDCM0379  CL11 PaTu 8988t C50(0.99); C267(0.96); C272(0.96); C355(0.99)  LDD1258  [6]
 LDCM0380  CL110 PaTu 8988t C314(1.61); C50(1.58); C267(1.37); C272(1.37)  LDD1259  [6]
 LDCM0381  CL111 PaTu 8988t C314(1.46); C50(1.77); C267(1.29); C272(1.29)  LDD1260  [6]
 LDCM0382  CL112 PaTu 8988t C322(1.10); C50(0.87); C267(0.96); C272(0.96)  LDD1261  [6]
 LDCM0383  CL113 PaTu 8988t C322(1.04); C50(0.92); C267(0.98); C272(0.98)  LDD1262  [6]
 LDCM0384  CL114 PaTu 8988t C322(0.83); C50(0.75); C267(0.85); C272(0.85)  LDD1263  [6]
 LDCM0385  CL115 PaTu 8988t C322(0.98); C50(0.94); C267(0.96); C272(0.96)  LDD1264  [6]
 LDCM0386  CL116 PaTu 8988t C322(1.31); C50(1.10); C267(0.95); C272(0.95)  LDD1265  [6]
 LDCM0387  CL117 PaTu 8988t C355(1.27); C359(1.27)  LDD1266  [6]
 LDCM0388  CL118 PaTu 8988t C355(1.51); C359(1.51)  LDD1267  [6]
 LDCM0389  CL119 PaTu 8988t C355(1.40); C359(1.40)  LDD1268  [6]
 LDCM0390  CL12 PaTu 8988t C50(1.07); C267(1.33); C272(1.33); C355(1.33)  LDD1269  [6]
 LDCM0391  CL120 PaTu 8988t C355(1.34); C359(1.34)  LDD1270  [6]
 LDCM0392  CL121 PaTu 8988t C317(3.03); C314(3.03); C229(1.36); C239(1.36)  LDD1271  [6]
 LDCM0393  CL122 PaTu 8988t C317(1.96); C314(1.96); C229(1.59); C239(1.59)  LDD1272  [6]
 LDCM0394  CL123 PaTu 8988t C317(2.59); C314(2.59); C229(1.62); C239(1.62)  LDD1273  [6]
 LDCM0395  CL124 PaTu 8988t C317(1.27); C314(1.27); C229(1.38); C239(1.38)  LDD1274  [6]
 LDCM0396  CL125 PaTu 8988t C267(0.78); C272(0.78); C355(1.05); C359(1.05)  LDD1275  [6]
 LDCM0397  CL126 PaTu 8988t C267(0.51); C272(0.51); C355(0.43); C359(0.43)  LDD1276  [6]
 LDCM0398  CL127 PaTu 8988t C267(1.04); C272(1.04); C355(1.18); C359(1.18)  LDD1277  [6]
 LDCM0399  CL128 PaTu 8988t C267(1.03); C272(1.03); C355(1.32); C359(1.32)  LDD1278  [6]
 LDCM0400  CL13 PaTu 8988t C50(1.10); C267(1.07); C272(1.07); C355(0.96)  LDD1279  [6]
 LDCM0401  CL14 PaTu 8988t C50(1.37); C267(1.39); C272(1.39); C355(1.47)  LDD1280  [6]
 LDCM0402  CL15 PaTu 8988t C50(1.65); C267(1.24); C272(1.24); C355(1.45)  LDD1281  [6]
 LDCM0403  CL16 PaTu 8988t C100(1.17); C322(1.06); C229(1.51); C239(1.51)  LDD1282  [6]
 LDCM0404  CL17 PaTu 8988t C100(0.96); C322(1.06); C229(1.31); C239(1.31)  LDD1283  [6]
 LDCM0405  CL18 PaTu 8988t C100(1.62); C322(1.01); C229(1.56); C239(1.56)  LDD1284  [6]
 LDCM0406  CL19 PaTu 8988t C100(1.66); C322(1.33); C229(1.54); C239(1.54)  LDD1285  [6]
 LDCM0407  CL2 PaTu 8988t C50(1.30); C267(1.39); C272(1.39); C355(1.19)  LDD1286  [6]
 LDCM0408  CL20 PaTu 8988t C100(1.48); C322(0.98); C229(1.14); C239(1.14)  LDD1287  [6]
 LDCM0409  CL21 PaTu 8988t C100(1.14); C322(0.79); C229(0.78); C239(0.78)  LDD1288  [6]
 LDCM0410  CL22 PaTu 8988t C100(1.44); C322(1.22); C229(1.30); C239(1.30)  LDD1289  [6]
 LDCM0411  CL23 PaTu 8988t C100(1.12); C322(1.35); C229(1.26); C239(1.26)  LDD1290  [6]
 LDCM0412  CL24 PaTu 8988t C100(1.66); C322(1.33); C229(1.07); C239(1.07)  LDD1291  [6]
 LDCM0413  CL25 PaTu 8988t C100(1.38); C322(0.81); C229(0.89); C239(0.89)  LDD1292  [6]
 LDCM0414  CL26 PaTu 8988t C100(1.44); C322(0.88); C229(1.16); C239(1.16)  LDD1293  [6]
 LDCM0415  CL27 PaTu 8988t C100(1.83); C322(1.22); C229(1.18); C239(1.18)  LDD1294  [6]
 LDCM0416  CL28 PaTu 8988t C100(1.28); C322(0.93); C229(0.54); C239(0.54)  LDD1295  [6]
 LDCM0417  CL29 PaTu 8988t C100(1.39); C322(0.85); C229(0.49); C239(0.49)  LDD1296  [6]
 LDCM0418  CL3 PaTu 8988t C50(1.34); C267(0.94); C272(0.94); C355(1.30)  LDD1297  [6]
 LDCM0419  CL30 PaTu 8988t C100(1.50); C322(1.16); C229(1.45); C239(1.45)  LDD1298  [6]
 LDCM0420  CL31 PaTu 8988t C100(1.06); C317(1.60); C322(1.19); C314(2.28)  LDD1299  [6]
 LDCM0421  CL32 PaTu 8988t C100(1.37); C317(1.17); C322(1.25); C314(1.31)  LDD1300  [6]
 LDCM0422  CL33 PaTu 8988t C100(0.56); C317(0.70); C322(0.59); C314(0.80)  LDD1301  [6]
 LDCM0423  CL34 PaTu 8988t C100(1.51); C317(2.09); C322(1.48); C314(3.21)  LDD1302  [6]
 LDCM0424  CL35 PaTu 8988t C355(1.35); C359(1.23); C100(1.79); C317(1.72)  LDD1303  [6]
 LDCM0425  CL36 PaTu 8988t C100(0.29); C317(0.65); C322(0.42); C314(0.25)  LDD1304  [6]
 LDCM0426  CL37 PaTu 8988t C100(1.53); C317(1.58); C322(1.14); C314(1.59)  LDD1305  [6]
 LDCM0428  CL39 PaTu 8988t C100(0.98); C317(1.02); C322(1.12); C314(1.24)  LDD1307  [6]
 LDCM0429  CL4 PaTu 8988t C50(1.12); C267(1.13); C272(1.13); C355(1.19)  LDD1308  [6]
 LDCM0430  CL40 PaTu 8988t C100(1.16); C317(1.19); C322(1.30); C314(1.29)  LDD1309  [6]
 LDCM0431  CL41 PaTu 8988t C100(1.29); C317(1.09); C322(0.93); C314(1.29)  LDD1310  [6]
 LDCM0432  CL42 PaTu 8988t C100(1.59); C317(1.71); C322(1.04); C314(2.20)  LDD1311  [6]
 LDCM0433  CL43 PaTu 8988t C100(1.79); C317(1.53); C322(1.76); C314(1.66)  LDD1312  [6]
 LDCM0434  CL44 PaTu 8988t C100(2.15); C317(2.06); C322(1.38); C314(2.43)  LDD1313  [6]
 LDCM0435  CL45 PaTu 8988t C100(1.31); C317(1.02); C322(1.13); C314(1.24)  LDD1314  [6]
 LDCM0436  CL46 PaTu 8988t C317(0.72); C322(1.13); C355(1.04); C359(1.04)  LDD1315  [6]
 LDCM0437  CL47 PaTu 8988t C317(0.72); C322(0.99); C355(0.91); C359(0.91)  LDD1316  [6]
 LDCM0438  CL48 PaTu 8988t C317(0.77); C322(1.18); C355(0.90); C359(0.90)  LDD1317  [6]
 LDCM0439  CL49 PaTu 8988t C317(0.69); C322(1.58); C355(1.02); C359(1.02)  LDD1318  [6]
 LDCM0440  CL5 PaTu 8988t C50(1.59); C267(1.45); C272(1.45); C355(1.30)  LDD1319  [6]
 LDCM0441  CL50 PaTu 8988t C317(1.18); C322(1.25); C355(1.17); C359(1.17)  LDD1320  [6]
 LDCM0442  CL51 PaTu 8988t C317(0.60); C322(0.73); C355(0.58); C359(0.58)  LDD1321  [6]
 LDCM0443  CL52 PaTu 8988t C317(0.79); C322(1.53); C355(1.10); C359(1.10)  LDD1322  [6]
 LDCM0444  CL53 PaTu 8988t C317(1.20); C322(1.15); C355(1.24); C359(1.24)  LDD1323  [6]
 LDCM0445  CL54 PaTu 8988t C317(0.96); C322(1.68); C355(1.14); C359(1.14)  LDD1324  [6]
 LDCM0446  CL55 PaTu 8988t C317(0.73); C322(1.74); C355(1.10); C359(1.10)  LDD1325  [6]
 LDCM0447  CL56 PaTu 8988t C317(0.31); C322(1.46); C355(1.01); C359(1.01)  LDD1326  [6]
 LDCM0448  CL57 PaTu 8988t C317(1.02); C322(1.25); C355(0.92); C359(0.92)  LDD1327  [6]
 LDCM0449  CL58 PaTu 8988t C317(1.04); C322(1.29); C355(1.11); C359(1.11)  LDD1328  [6]
 LDCM0450  CL59 PaTu 8988t C317(1.45); C322(1.24); C355(1.03); C359(1.03)  LDD1329  [6]
 LDCM0451  CL6 PaTu 8988t C50(1.02); C267(0.83); C272(0.83); C355(1.11)  LDD1330  [6]
 LDCM0452  CL60 PaTu 8988t C317(0.81); C322(1.05); C355(0.88); C359(0.88)  LDD1331  [6]
 LDCM0453  CL61 PaTu 8988t C100(1.11); C317(1.16); C50(1.58); C267(1.20)  LDD1332  [6]
 LDCM0454  CL62 PaTu 8988t C100(2.02); C317(0.58); C50(2.43); C267(1.06)  LDD1333  [6]
 LDCM0455  CL63 PaTu 8988t C100(1.67); C317(0.90); C50(2.25); C267(0.96)  LDD1334  [6]
 LDCM0456  CL64 PaTu 8988t C100(1.25); C317(0.78); C50(1.58); C267(0.79)  LDD1335  [6]
 LDCM0457  CL65 PaTu 8988t C100(1.44); C317(0.84); C50(2.09); C267(1.19)  LDD1336  [6]
 LDCM0458  CL66 PaTu 8988t C100(1.27); C317(0.74); C50(1.48); C267(0.94)  LDD1337  [6]
 LDCM0459  CL67 PaTu 8988t C100(1.52); C317(0.93); C50(2.54); C267(1.03)  LDD1338  [6]
 LDCM0460  CL68 PaTu 8988t C100(1.51); C317(0.95); C50(2.30); C267(1.05)  LDD1339  [6]
 LDCM0461  CL69 PaTu 8988t C100(1.75); C317(0.68); C50(3.84); C267(1.36)  LDD1340  [6]
 LDCM0462  CL7 PaTu 8988t C50(1.40); C267(1.77); C272(1.77); C355(1.08)  LDD1341  [6]
 LDCM0463  CL70 PaTu 8988t C100(2.00); C317(0.73); C50(3.60); C267(1.80)  LDD1342  [6]
 LDCM0464  CL71 PaTu 8988t C100(1.53); C317(1.63); C50(1.67); C267(0.95)  LDD1343  [6]
 LDCM0465  CL72 PaTu 8988t C100(1.30); C317(0.57); C50(1.74); C267(1.00)  LDD1344  [6]
 LDCM0466  CL73 PaTu 8988t C100(3.51); C317(1.21); C50(3.49); C267(1.27)  LDD1345  [6]
 LDCM0467  CL74 PaTu 8988t C100(2.11); C317(0.86); C50(1.99); C267(1.29)  LDD1346  [6]
 LDCM0469  CL76 PaTu 8988t C100(1.29); C314(1.45); C50(1.06); C267(0.86)  LDD1348  [6]
 LDCM0470  CL77 PaTu 8988t C100(1.40); C314(0.86); C50(2.21); C267(1.02)  LDD1349  [6]
 LDCM0471  CL78 PaTu 8988t C100(2.21); C314(1.08); C50(1.83); C267(1.20)  LDD1350  [6]
 LDCM0472  CL79 PaTu 8988t C100(1.79); C314(1.06); C50(2.19); C267(1.25)  LDD1351  [6]
 LDCM0473  CL8 PaTu 8988t C50(0.80); C267(1.64); C272(1.64); C355(1.04)  LDD1352  [6]
 LDCM0474  CL80 PaTu 8988t C100(1.78); C314(2.08); C50(1.72); C267(1.19)  LDD1353  [6]
 LDCM0475  CL81 PaTu 8988t C100(1.80); C314(1.26); C50(3.76); C267(1.27)  LDD1354  [6]
 LDCM0476  CL82 PaTu 8988t C100(1.72); C314(1.33); C50(2.65); C267(1.25)  LDD1355  [6]
 LDCM0477  CL83 PaTu 8988t C100(2.11); C314(1.50); C50(3.07); C267(1.25)  LDD1356  [6]
 LDCM0478  CL84 PaTu 8988t C100(1.42); C314(1.18); C50(1.52); C267(1.07)  LDD1357  [6]
 LDCM0479  CL85 PaTu 8988t C100(1.68); C314(0.66); C50(1.03); C267(1.27)  LDD1358  [6]
 LDCM0480  CL86 PaTu 8988t C100(1.71); C314(0.81); C50(1.77); C267(1.34)  LDD1359  [6]
 LDCM0481  CL87 PaTu 8988t C100(1.66); C314(1.04); C50(2.25); C267(1.05)  LDD1360  [6]
 LDCM0482  CL88 PaTu 8988t C100(2.24); C314(1.76); C50(2.29); C267(1.42)  LDD1361  [6]
 LDCM0483  CL89 PaTu 8988t C100(1.65); C314(0.99); C50(2.09); C267(1.05)  LDD1362  [6]
 LDCM0484  CL9 PaTu 8988t C50(1.30); C267(1.25); C272(1.25); C355(1.56)  LDD1363  [6]
 LDCM0485  CL90 PaTu 8988t C100(1.14); C314(0.56); C50(1.06); C267(1.02)  LDD1364  [6]
 LDCM0486  CL91 PaTu 8988t C229(1.27); C239(1.27); C355(0.94); C359(0.94)  LDD1365  [6]
 LDCM0487  CL92 PaTu 8988t C229(1.10); C239(1.10); C355(0.89); C359(0.89)  LDD1366  [6]
 LDCM0488  CL93 PaTu 8988t C229(1.66); C239(1.66); C355(1.28); C359(1.28)  LDD1367  [6]
 LDCM0489  CL94 PaTu 8988t C229(1.77); C239(1.77); C355(1.20); C359(1.20)  LDD1368  [6]
 LDCM0490  CL95 PaTu 8988t C229(2.13); C239(2.13); C355(1.14); C359(1.14)  LDD1369  [6]
 LDCM0491  CL96 PaTu 8988t C229(2.02); C239(2.02); C355(1.04); C359(1.04)  LDD1370  [6]
 LDCM0492  CL97 PaTu 8988t C229(1.47); C239(1.47); C355(1.03); C359(1.03)  LDD1371  [6]
 LDCM0493  CL98 PaTu 8988t C229(2.15); C239(2.15); C355(1.21); C359(1.21)  LDD1372  [6]
 LDCM0494  CL99 PaTu 8988t C229(2.06); C239(2.06); C355(1.46); C359(1.46)  LDD1373  [6]
 LDCM0495  E2913 HEK-293T C303(1.13)  LDD1698  [9]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C303(2.29); C32(1.58); C314(1.28); C30(1.26)  LDD1702  [3]
 LDCM0468  Fragment33 PaTu 8988t C100(1.68); C317(0.72); C50(2.06); C267(1.31)  LDD1347  [6]
 LDCM0427  Fragment51 PaTu 8988t C100(1.70); C317(1.18); C322(1.10); C314(1.46)  LDD1306  [6]
 LDCM0022  KB02 42-MG-BA C70(1.07)  LDD2244  [10]
 LDCM0023  KB03 MDA-MB-231 C303(5.61); C26(2.74); C78(2.60); C272(2.50)  LDD1701  [3]
 LDCM0024  KB05 G361 C100(1.89); C39(2.50); C303(4.99); C78(2.51)  LDD3311  [10]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C337(1.08); C100(0.72)  LDD2121  [3]
 LDCM0109  NEM HeLa N.A.  LDD0232  [5]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C337(1.02); C100(0.53)  LDD2089  [3]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C272(1.03)  LDD2092  [3]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C100(0.94); C267(1.95)  LDD2097  [3]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C26(2.43)  LDD2098  [3]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C100(1.15); C26(1.87); C258(0.84)  LDD2101  [3]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C26(0.98)  LDD2105  [3]
 LDCM0517  Nucleophilic fragment 21b MDA-MB-231 C267(0.49)  LDD2110  [3]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C100(0.72); C258(0.66)  LDD2115  [3]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C100(0.90); C258(0.51)  LDD2134  [3]
 LDCM0551  Nucleophilic fragment 5b MDA-MB-231 C267(1.71)  LDD2145  [3]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C337(0.54); C100(0.63); C78(4.13); C267(0.46)  LDD2148  [3]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C100(0.49); C70(0.47)  LDD2150  [3]
 LDCM0016  Ranjitkar_cp1 MDA-MB-231 2.33  LDD0123  [4]
 LDCM0021  THZ1 HCT 116 C267(3.42); C272(3.42)  LDD2173  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Sphingomyelin phosphodiesterase 2 (SMPD2) Neutral sphingomyelinase family O60906
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ubiquilin-2 (UBQLN2) . Q9UHD9

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 A chemical proteomics approach for global mapping of functional lysines on cell surface of living cell. Nat Commun. 2024 Apr 8;15(1):2997. doi: 10.1038/s41467-024-47033-w.
Mass spectrometry data entry: PXD042888
3 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
4 Appendage and Scaffold Diverse Fully Functionalized Small-Molecule Probes via a Minimalist Terminal Alkyne-Aliphatic Diazirine Isocyanide. J Org Chem. 2018 Sep 21;83(18):11245-11253. doi: 10.1021/acs.joc.8b01831. Epub 2018 Aug 31.
5 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
6 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
7 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
8 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
9 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
10 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840