Details of the Target
General Information of Target
Target ID | LDTP00360 | |||||
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Target Name | Phospholipid transfer protein C2CD2L (C2CD2L) | |||||
Gene Name | C2CD2L | |||||
Gene ID | 9854 | |||||
Synonyms |
KIAA0285; TMEM24; Phospholipid transfer protein C2CD2L; C2 domain-containing protein 2-like; C2CD2-like; Transmembrane protein 24 |
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3D Structure | ||||||
Sequence |
MDPGWGQRDVGWAALLILFAASLLTVFAWLLQYARGLWLARARGDRGPGPALAGEPAGSL
RELGVWRSLLRLRATRAGAAEEPGVRGLLASLFAFKSFRENWQRAWVRALNEQACRNGSS IQIAFEEVPQLPPRASISHVTCVDQSEHTMVLRCQLSAEEVRFPVSVTQQSPAAVSMETY HVTLTLPPTQLEVNLEEIPGEGLLISWAFTDRPDLSLTVLPKLQARERGEEQVELSTIEE LIKDAIVSTQPAMMVNLRACSAPGGLVPSEKPPMMPQAQPAIPRPNRLFLRQLRASHLGN ELEGTEELCCVAELDNPMQQKWTKPARAGSEVEWTEDLALDLGPQSRELTLKVLRSSSCG DTELLGQATLPVGSPSRPLSRRQLCPLTPGPGKALGPAATMAVELHYEEGSPRNLGTPTS STPRPSITPTKKIELDRTIMPDGTIVTTVTTVQSRPRIDGKLDSPSRSPSKVEVTEKTTT VLSESSGPSNTSHSSSRDSHLSNGLDPVAETAIRQLTEPSGRVAKKTPTKRSTLIISGVS KVPIAQDELALSLGYAASLEASVQDDAGTSGGPSSPPSDPPAMSPGPLDALSSPTSVQEA DETTRSDISERPSVDDIESETGSTGALETRSLKDHKVSFLRSGTKLIFRRRPRQKEAGLS QSHDDLSNATATPSVRKKAGSFSRRLIKRFSFKSKPKANGNPSPQL |
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Target Bioclass |
Transporter and channel
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Subcellular location |
Endoplasmic reticulum membrane
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Function |
Lipid-binding protein that transports phosphatidylinositol, the precursor of phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2), from its site of synthesis in the endoplasmic reticulum to the cell membrane. It thereby maintains the pool of cell membrane phosphoinositides, which are degraded during phospholipase C (PLC) signaling. Plays a key role in the coordination of Ca(2+) and phosphoinositide signaling: localizes to sites of contact between the endoplasmic reticulum and the cell membrane, where it tethers the two bilayers. In response to elevation of cytosolic Ca(2+), it is phosphorylated at its C-terminus and dissociates from the cell membrane, abolishing phosphatidylinositol transport to the cell membrane. Positively regulates insulin secretion in response to glucose: phosphatidylinositol transfer to the cell membrane allows replenishment of PI(4,5)P2 pools and calcium channel opening, priming a new population of insulin granules.
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Uniprot ID | ||||||
Ensemble ID | ||||||
HGNC ID |
Target Site Mutations in Different Cell Lines
Cell line | Mutation details | Probe for labeling this protein in this cell | |||
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A673 | SNV: p.E178D | DBIA Probe Info | |||
CALU1 | SNV: p.A40G | DBIA Probe Info | |||
DU145 | SNV: p.Ter707CextTer58 | DBIA Probe Info | |||
HCC1937 | SNV: p.L551V | DBIA Probe Info | |||
HCT15 | SNV: p.D616V | DBIA Probe Info | |||
KYSE30 | SNV: p.E160K | . | |||
NCIH1299 | SNV: p.P587R | . | |||
NUGC3 | SNV: p.T422N | DBIA Probe Info | |||
RL | SNV: p.R43P | DBIA Probe Info | |||
SKN | SNV: p.R162P | DBIA Probe Info | |||
SW756 | SNV: p.A114S | . | |||
T24 | SNV: p.D616N; p.E620K | . |
Probe(s) Labeling This Target
ABPP Probe
Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
---|---|---|---|---|---|
m-APA Probe Info |
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12.84 | LDD0402 | [1] | |
STPyne Probe Info |
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K352(2.04) | LDD0277 | [2] | |
DBIA Probe Info |
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C115(2.27) | LDD3314 | [3] | |
BTD Probe Info |
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C115(1.02) | LDD1700 | [4] | |
IA-alkyne Probe Info |
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N.A. | LDD0036 | [5] | |
Lodoacetamide azide Probe Info |
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C115(0.00); C142(0.00) | LDD0037 | [5] | |
NAIA_5 Probe Info |
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N.A. | LDD2224 | [6] | |
IPM Probe Info |
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C115(0.00); C359(0.00) | LDD0147 | [7] | |
TFBX Probe Info |
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C154(0.00); C359(0.00); C115(0.00) | LDD0148 | [7] | |
Phosphinate-6 Probe Info |
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N.A. | LDD0018 | [8] |
Competitor(s) Related to This Target
Competitor ID | Name | Cell line | Binding Site(Ratio) | Interaction ID | Ref |
---|---|---|---|---|---|
LDCM0558 | 2-Cyano-N-phenylacetamide | MDA-MB-231 | C115(1.01) | LDD2152 | [4] |
LDCM0026 | 4SU-RNA+native RNA | HEK-293T | C359(2.34) | LDD0372 | [9] |
LDCM0214 | AC1 | HEK-293T | C115(1.01); C359(1.14); C385(1.03); C260(1.14) | LDD1507 | [10] |
LDCM0215 | AC10 | HEK-293T | C115(0.99); C359(1.04); C385(0.89) | LDD1508 | [10] |
LDCM0226 | AC11 | HEK-293T | C115(0.95); C359(1.05); C385(0.97); C260(1.15) | LDD1509 | [10] |
LDCM0237 | AC12 | HEK-293T | C115(0.98); C359(1.00); C385(1.11); C260(0.98) | LDD1510 | [10] |
LDCM0259 | AC14 | HEK-293T | C115(1.19); C359(0.94); C385(1.15); C260(0.96) | LDD1512 | [10] |
LDCM0270 | AC15 | HEK-293T | C115(1.01); C359(1.01); C385(1.12); C260(1.03) | LDD1513 | [10] |
LDCM0276 | AC17 | HEK-293T | C115(1.02); C359(1.07); C385(0.98); C260(1.05) | LDD1515 | [10] |
LDCM0277 | AC18 | HEK-293T | C115(0.98); C359(0.90); C385(1.03) | LDD1516 | [10] |
LDCM0278 | AC19 | HEK-293T | C115(0.90); C359(1.18); C385(1.00); C260(1.11) | LDD1517 | [10] |
LDCM0279 | AC2 | HEK-293T | C115(0.96); C359(0.98); C385(0.95) | LDD1518 | [10] |
LDCM0280 | AC20 | HEK-293T | C115(0.94); C359(1.11); C385(1.01); C260(0.94) | LDD1519 | [10] |
LDCM0281 | AC21 | HEK-293T | C115(1.00); C359(1.13); C385(1.10); C260(0.91) | LDD1520 | [10] |
LDCM0282 | AC22 | HEK-293T | C115(0.95); C359(0.99); C385(1.07); C260(1.09) | LDD1521 | [10] |
LDCM0283 | AC23 | HEK-293T | C115(0.94); C359(0.96); C385(1.19); C260(0.94) | LDD1522 | [10] |
LDCM0284 | AC24 | HEK-293T | C115(1.09); C359(0.98); C385(0.89); C260(0.87) | LDD1523 | [10] |
LDCM0285 | AC25 | HEK-293T | C115(1.01); C359(1.05); C385(0.98); C260(1.07) | LDD1524 | [10] |
LDCM0286 | AC26 | HEK-293T | C115(0.96); C359(0.93); C385(0.93) | LDD1525 | [10] |
LDCM0287 | AC27 | HEK-293T | C115(0.89); C359(0.95); C385(1.02); C260(1.07) | LDD1526 | [10] |
LDCM0288 | AC28 | HEK-293T | C115(0.95); C359(0.97); C385(1.05); C260(0.89) | LDD1527 | [10] |
LDCM0289 | AC29 | HEK-293T | C115(1.05); C359(0.98); C385(1.05); C260(0.93) | LDD1528 | [10] |
LDCM0290 | AC3 | HEK-293T | C115(0.92); C359(0.99); C385(0.95); C260(1.12) | LDD1529 | [10] |
LDCM0291 | AC30 | HEK-293T | C115(1.01); C359(1.08); C385(1.01); C260(1.01) | LDD1530 | [10] |
LDCM0292 | AC31 | HEK-293T | C115(0.93); C359(1.00); C385(1.08); C260(1.02) | LDD1531 | [10] |
LDCM0293 | AC32 | HEK-293T | C115(1.02); C359(0.87); C385(1.02); C260(0.86) | LDD1532 | [10] |
LDCM0294 | AC33 | HEK-293T | C115(1.03); C359(1.07); C385(0.94); C260(1.13) | LDD1533 | [10] |
LDCM0295 | AC34 | HEK-293T | C115(1.00); C359(0.80); C385(1.05) | LDD1534 | [10] |
LDCM0296 | AC35 | HEK-293T | C115(0.93); C359(1.09); C385(1.04); C260(1.12) | LDD1535 | [10] |
LDCM0297 | AC36 | HEK-293T | C115(1.02); C359(1.00); C385(1.10); C260(1.20) | LDD1536 | [10] |
LDCM0298 | AC37 | HEK-293T | C115(0.97); C359(1.03); C385(1.08); C260(1.04) | LDD1537 | [10] |
LDCM0299 | AC38 | HEK-293T | C115(1.04); C359(1.00); C385(1.10); C260(1.05) | LDD1538 | [10] |
LDCM0300 | AC39 | HEK-293T | C115(0.93); C359(1.12); C385(1.11); C260(0.89) | LDD1539 | [10] |
LDCM0301 | AC4 | HEK-293T | C115(1.02); C359(1.04); C385(0.98); C260(0.95) | LDD1540 | [10] |
LDCM0302 | AC40 | HEK-293T | C115(1.02); C359(0.99); C385(0.99); C260(1.00) | LDD1541 | [10] |
LDCM0303 | AC41 | HEK-293T | C115(0.99); C359(1.10); C385(1.10); C260(0.98) | LDD1542 | [10] |
LDCM0304 | AC42 | HEK-293T | C115(1.05); C359(0.99); C385(0.99) | LDD1543 | [10] |
LDCM0305 | AC43 | HEK-293T | C115(0.97); C359(1.04); C385(0.97); C260(1.17) | LDD1544 | [10] |
LDCM0306 | AC44 | HEK-293T | C115(1.02); C359(1.08); C385(1.09); C260(0.97) | LDD1545 | [10] |
LDCM0307 | AC45 | HEK-293T | C115(0.99); C359(1.05); C385(1.06); C260(1.01) | LDD1546 | [10] |
LDCM0308 | AC46 | HEK-293T | C115(1.09); C359(1.23); C385(1.11); C260(1.07) | LDD1547 | [10] |
LDCM0309 | AC47 | HEK-293T | C115(0.87); C359(1.13); C385(1.04); C260(0.94) | LDD1548 | [10] |
LDCM0310 | AC48 | HEK-293T | C115(1.10); C359(1.02); C385(0.97); C260(0.93) | LDD1549 | [10] |
LDCM0311 | AC49 | HEK-293T | C115(1.04); C359(1.15); C385(1.05); C260(1.07) | LDD1550 | [10] |
LDCM0312 | AC5 | HEK-293T | C115(0.92); C359(1.10); C385(1.02); C260(0.94) | LDD1551 | [10] |
LDCM0313 | AC50 | HEK-293T | C115(0.96); C359(0.96); C385(0.88) | LDD1552 | [10] |
LDCM0314 | AC51 | HEK-293T | C115(0.99); C359(1.07); C385(1.07); C260(1.10) | LDD1553 | [10] |
LDCM0315 | AC52 | HEK-293T | C115(1.00); C359(1.07); C385(1.09); C260(0.99) | LDD1554 | [10] |
LDCM0316 | AC53 | HEK-293T | C115(0.97); C359(1.08); C385(1.00); C260(1.05) | LDD1555 | [10] |
LDCM0317 | AC54 | HEK-293T | C115(1.06); C359(1.04); C385(1.05); C260(0.86) | LDD1556 | [10] |
LDCM0318 | AC55 | HEK-293T | C115(0.89); C359(1.05); C385(1.05); C260(1.08) | LDD1557 | [10] |
LDCM0319 | AC56 | HEK-293T | C115(1.01); C359(0.96); C385(1.19); C260(0.87) | LDD1558 | [10] |
LDCM0320 | AC57 | HEK-293T | C115(1.06); C359(1.19); C385(0.92); C260(1.01) | LDD1559 | [10] |
LDCM0321 | AC58 | HEK-293T | C115(0.97); C359(1.01); C385(0.90) | LDD1560 | [10] |
LDCM0322 | AC59 | HEK-293T | C115(1.01); C359(1.07); C385(0.96); C260(1.13) | LDD1561 | [10] |
LDCM0323 | AC6 | HEK-293T | C115(1.11); C359(1.32); C385(1.07); C260(1.22) | LDD1562 | [10] |
LDCM0324 | AC60 | HEK-293T | C115(0.96); C359(1.04); C385(1.11); C260(1.06) | LDD1563 | [10] |
LDCM0325 | AC61 | HEK-293T | C115(0.97); C359(1.13); C385(0.93); C260(1.10) | LDD1564 | [10] |
LDCM0326 | AC62 | HEK-293T | C115(1.10); C359(1.02); C385(1.03); C260(1.11) | LDD1565 | [10] |
LDCM0327 | AC63 | HEK-293T | C115(1.03); C359(1.10); C385(1.02); C260(1.16) | LDD1566 | [10] |
LDCM0328 | AC64 | HEK-293T | C115(0.96); C359(1.09); C385(1.13); C260(1.01) | LDD1567 | [10] |
LDCM0334 | AC7 | HEK-293T | C115(1.01); C359(1.03); C385(1.09); C260(1.10) | LDD1568 | [10] |
LDCM0345 | AC8 | HEK-293T | C115(1.04); C359(0.91); C385(1.17); C260(0.91) | LDD1569 | [10] |
LDCM0248 | AKOS034007472 | HEK-293T | C115(1.04); C359(1.16); C385(1.06); C260(1.06) | LDD1511 | [10] |
LDCM0356 | AKOS034007680 | HEK-293T | C115(1.12); C359(1.11); C385(0.98); C260(0.86) | LDD1570 | [10] |
LDCM0275 | AKOS034007705 | HEK-293T | C115(1.16); C359(1.06); C385(0.95); C260(0.94) | LDD1514 | [10] |
LDCM0156 | Aniline | NCI-H1299 | 14.78 | LDD0403 | [1] |
LDCM0498 | BS-3668 | MDA-MB-231 | C115(0.64) | LDD2091 | [4] |
LDCM0632 | CL-Sc | Hep-G2 | C142(20.00) | LDD2227 | [6] |
LDCM0367 | CL1 | HEK-293T | C115(0.97); C359(0.95); C385(1.00); C260(1.16) | LDD1571 | [10] |
LDCM0368 | CL10 | HEK-293T | C115(1.00); C359(0.81); C385(1.57); C260(1.87) | LDD1572 | [10] |
LDCM0369 | CL100 | HEK-293T | C115(0.85); C359(1.13); C385(1.01); C260(1.05) | LDD1573 | [10] |
LDCM0370 | CL101 | HEK-293T | C115(1.04); C359(1.01); C385(1.01); C260(1.16) | LDD1574 | [10] |
LDCM0371 | CL102 | HEK-293T | C115(0.97); C359(1.16); C385(1.02); C260(1.14) | LDD1575 | [10] |
LDCM0372 | CL103 | HEK-293T | C115(1.12); C359(0.97); C385(1.07); C260(0.97) | LDD1576 | [10] |
LDCM0373 | CL104 | HEK-293T | C115(1.01); C359(1.17); C385(1.07); C260(1.11) | LDD1577 | [10] |
LDCM0374 | CL105 | HEK-293T | C115(0.99); C359(1.06); C385(1.03); C260(1.08) | LDD1578 | [10] |
LDCM0375 | CL106 | HEK-293T | C115(0.96); C359(1.08); C385(1.05); C260(1.13) | LDD1579 | [10] |
LDCM0376 | CL107 | HEK-293T | C115(1.06); C359(0.87); C385(0.99); C260(0.89) | LDD1580 | [10] |
LDCM0377 | CL108 | HEK-293T | C115(1.01); C359(0.99); C385(1.06); C260(1.05) | LDD1581 | [10] |
LDCM0378 | CL109 | HEK-293T | C115(1.08); C359(1.16); C385(0.99); C260(1.14) | LDD1582 | [10] |
LDCM0379 | CL11 | HEK-293T | C115(1.03); C359(1.08); C385(2.03); C260(1.08) | LDD1583 | [10] |
LDCM0380 | CL110 | HEK-293T | C115(0.95); C359(1.03); C385(1.02); C260(0.91) | LDD1584 | [10] |
LDCM0381 | CL111 | HEK-293T | C115(1.08); C359(0.89); C385(1.11); C260(1.04) | LDD1585 | [10] |
LDCM0382 | CL112 | HEK-293T | C115(0.93); C359(1.09); C385(1.05); C260(1.11) | LDD1586 | [10] |
LDCM0383 | CL113 | HEK-293T | C115(0.99); C359(0.97); C385(0.94); C260(1.25) | LDD1587 | [10] |
LDCM0384 | CL114 | HEK-293T | C115(0.99); C359(1.06); C385(1.11); C260(1.18) | LDD1588 | [10] |
LDCM0385 | CL115 | HEK-293T | C115(1.02); C359(1.17); C385(0.97); C260(1.00) | LDD1589 | [10] |
LDCM0386 | CL116 | HEK-293T | C115(0.92); C359(1.18); C385(1.04); C260(1.11) | LDD1590 | [10] |
LDCM0387 | CL117 | HEK-293T | C115(0.98); C359(1.17); C385(0.94); C260(1.21) | LDD1591 | [10] |
LDCM0388 | CL118 | HEK-293T | C115(0.98); C359(1.15); C385(1.04); C260(1.08) | LDD1592 | [10] |
LDCM0389 | CL119 | HEK-293T | C115(1.05); C359(1.04); C385(0.97); C260(1.06) | LDD1593 | [10] |
LDCM0390 | CL12 | HEK-293T | C115(0.98); C359(0.94); C385(1.05); C260(0.95) | LDD1594 | [10] |
LDCM0391 | CL120 | HEK-293T | C115(0.95); C359(0.95); C385(1.09); C260(1.11) | LDD1595 | [10] |
LDCM0392 | CL121 | HEK-293T | C115(1.00); C359(0.95); C385(0.99); C260(1.03) | LDD1596 | [10] |
LDCM0393 | CL122 | HEK-293T | C115(0.91); C359(1.11); C385(1.01); C260(1.11) | LDD1597 | [10] |
LDCM0394 | CL123 | HEK-293T | C115(0.97); C359(0.82); C385(1.05); C260(1.00) | LDD1598 | [10] |
LDCM0395 | CL124 | HEK-293T | C115(0.92); C359(1.08); C385(1.07); C260(1.03) | LDD1599 | [10] |
LDCM0396 | CL125 | HEK-293T | C115(1.01); C359(0.98); C385(1.04); C260(1.25) | LDD1600 | [10] |
LDCM0397 | CL126 | HEK-293T | C115(1.00); C359(1.16); C385(1.03); C260(1.10) | LDD1601 | [10] |
LDCM0398 | CL127 | HEK-293T | C115(1.08); C359(1.08); C385(1.01); C260(1.03) | LDD1602 | [10] |
LDCM0399 | CL128 | HEK-293T | C115(0.94); C359(1.16); C385(1.00); C260(1.00) | LDD1603 | [10] |
LDCM0400 | CL13 | HEK-293T | C115(1.02); C359(1.09); C385(1.00); C260(1.28) | LDD1604 | [10] |
LDCM0401 | CL14 | HEK-293T | C115(0.89); C359(1.17); C385(1.13); C260(1.06) | LDD1605 | [10] |
LDCM0402 | CL15 | HEK-293T | C115(0.98); C359(0.91); C385(1.16); C260(1.06) | LDD1606 | [10] |
LDCM0403 | CL16 | HEK-293T | C115(0.97); C359(1.16); C385(1.14); C260(1.03) | LDD1607 | [10] |
LDCM0404 | CL17 | HEK-293T | C115(0.97); C359(2.03); C385(1.13); C260(1.19) | LDD1608 | [10] |
LDCM0405 | CL18 | HEK-293T | C115(1.00); C359(1.10); C385(0.92) | LDD1609 | [10] |
LDCM0406 | CL19 | HEK-293T | C115(0.94); C359(1.09); C385(1.02); C260(1.02) | LDD1610 | [10] |
LDCM0407 | CL2 | HEK-293T | C115(1.00); C359(1.13); C385(1.29); C260(1.05) | LDD1611 | [10] |
LDCM0408 | CL20 | HEK-293T | C115(1.07); C359(1.04); C385(1.81); C260(0.96) | LDD1612 | [10] |
LDCM0409 | CL21 | HEK-293T | C115(0.91); C359(1.02); C385(1.92); C260(0.97) | LDD1613 | [10] |
LDCM0410 | CL22 | HEK-293T | C115(1.12); C359(0.95); C385(1.23); C260(1.01) | LDD1614 | [10] |
LDCM0411 | CL23 | HEK-293T | C115(0.86); C359(0.99); C385(2.11); C260(1.03) | LDD1615 | [10] |
LDCM0412 | CL24 | HEK-293T | C115(1.04); C359(1.08); C385(1.27); C260(0.98) | LDD1616 | [10] |
LDCM0413 | CL25 | HEK-293T | C115(0.89); C359(1.05); C385(0.97); C260(1.21) | LDD1617 | [10] |
LDCM0414 | CL26 | HEK-293T | C115(0.94); C359(1.08); C385(1.02); C260(0.95) | LDD1618 | [10] |
LDCM0415 | CL27 | HEK-293T | C115(1.15); C359(0.90); C385(1.02); C260(0.97) | LDD1619 | [10] |
LDCM0416 | CL28 | HEK-293T | C115(0.96); C359(1.09); C385(1.12); C260(1.07) | LDD1620 | [10] |
LDCM0417 | CL29 | HEK-293T | C115(1.07); C359(1.08); C385(1.12); C260(1.05) | LDD1621 | [10] |
LDCM0418 | CL3 | HEK-293T | C115(1.06); C359(0.97); C385(1.01); C260(1.11) | LDD1622 | [10] |
LDCM0419 | CL30 | HEK-293T | C115(1.00); C359(0.96); C385(0.91) | LDD1623 | [10] |
LDCM0420 | CL31 | HEK-293T | C115(0.99); C359(0.94); C385(1.09); C260(1.06) | LDD1624 | [10] |
LDCM0421 | CL32 | HEK-293T | C115(0.98); C359(1.08); C385(1.61); C260(0.73) | LDD1625 | [10] |
LDCM0422 | CL33 | HEK-293T | C115(0.96); C359(0.99); C385(1.82); C260(1.26) | LDD1626 | [10] |
LDCM0423 | CL34 | HEK-293T | C115(1.06); C359(0.99); C385(1.46); C260(1.02) | LDD1627 | [10] |
LDCM0424 | CL35 | HEK-293T | C115(0.86); C359(1.00); C385(1.97); C260(0.95) | LDD1628 | [10] |
LDCM0425 | CL36 | HEK-293T | C115(0.98); C359(1.04); C385(1.02); C260(0.90) | LDD1629 | [10] |
LDCM0426 | CL37 | HEK-293T | C115(0.97); C359(1.08); C385(0.98); C260(1.09) | LDD1630 | [10] |
LDCM0428 | CL39 | HEK-293T | C115(0.96); C359(0.92); C385(1.01); C260(1.02) | LDD1632 | [10] |
LDCM0429 | CL4 | HEK-293T | C115(0.98); C359(1.03); C385(1.15); C260(1.14) | LDD1633 | [10] |
LDCM0430 | CL40 | HEK-293T | C115(0.96); C359(0.97); C385(1.08); C260(1.04) | LDD1634 | [10] |
LDCM0431 | CL41 | HEK-293T | C115(1.05); C359(1.28); C385(1.17); C260(1.17) | LDD1635 | [10] |
LDCM0432 | CL42 | HEK-293T | C115(1.04); C359(1.10); C385(1.25) | LDD1636 | [10] |
LDCM0433 | CL43 | HEK-293T | C115(1.01); C359(0.91); C385(1.08); C260(0.94) | LDD1637 | [10] |
LDCM0434 | CL44 | HEK-293T | C115(1.00); C359(1.03); C385(1.55); C260(1.14) | LDD1638 | [10] |
LDCM0435 | CL45 | HEK-293T | C115(1.03); C359(1.13); C385(1.86); C260(1.09) | LDD1639 | [10] |
LDCM0436 | CL46 | HEK-293T | C115(1.09); C359(0.89); C385(1.33); C260(1.00) | LDD1640 | [10] |
LDCM0437 | CL47 | HEK-293T | C115(0.88); C359(0.96); C385(1.93); C260(0.99) | LDD1641 | [10] |
LDCM0438 | CL48 | HEK-293T | C115(1.04); C359(0.88); C385(1.04); C260(0.98) | LDD1642 | [10] |
LDCM0439 | CL49 | HEK-293T | C115(1.05); C359(0.98); C385(0.96); C260(1.29) | LDD1643 | [10] |
LDCM0440 | CL5 | HEK-293T | C115(1.05); C359(1.25); C385(0.95); C260(0.99) | LDD1644 | [10] |
LDCM0441 | CL50 | HEK-293T | C115(0.94); C359(1.05); C385(1.16); C260(1.17) | LDD1645 | [10] |
LDCM0443 | CL52 | HEK-293T | C115(1.00); C359(1.06); C385(1.12); C260(1.11) | LDD1646 | [10] |
LDCM0444 | CL53 | HEK-293T | C115(1.02); C359(1.68); C385(1.22); C260(1.18) | LDD1647 | [10] |
LDCM0445 | CL54 | HEK-293T | C115(0.84); C359(0.96); C385(1.11) | LDD1648 | [10] |
LDCM0446 | CL55 | HEK-293T | C115(0.92); C359(1.05); C385(1.11); C260(0.97) | LDD1649 | [10] |
LDCM0447 | CL56 | HEK-293T | C115(0.96); C359(1.11); C385(1.71); C260(0.91) | LDD1650 | [10] |
LDCM0448 | CL57 | HEK-293T | C115(0.91); C359(1.01); C385(2.07); C260(1.20) | LDD1651 | [10] |
LDCM0449 | CL58 | HEK-293T | C115(1.19); C359(0.97); C385(1.42); C260(1.16) | LDD1652 | [10] |
LDCM0450 | CL59 | HEK-293T | C115(1.02); C359(1.09); C385(1.92); C260(0.92) | LDD1653 | [10] |
LDCM0451 | CL6 | HEK-293T | C115(0.90); C359(0.97); C385(0.93) | LDD1654 | [10] |
LDCM0452 | CL60 | HEK-293T | C115(1.17); C359(0.88); C385(0.96); C260(0.99) | LDD1655 | [10] |
LDCM0453 | CL61 | HEK-293T | C115(1.01); C359(1.04); C385(0.96); C260(1.33) | LDD1656 | [10] |
LDCM0454 | CL62 | HEK-293T | C115(0.96); C359(1.13); C385(1.07); C260(1.03) | LDD1657 | [10] |
LDCM0455 | CL63 | HEK-293T | C115(1.05); C359(1.02); C385(1.02); C260(1.06) | LDD1658 | [10] |
LDCM0456 | CL64 | HEK-293T | C115(0.90); C359(1.03); C385(1.18); C260(1.14) | LDD1659 | [10] |
LDCM0457 | CL65 | HEK-293T | C115(1.12); C359(1.12); C385(0.96); C260(0.93) | LDD1660 | [10] |
LDCM0458 | CL66 | HEK-293T | C115(0.99); C359(0.87); C385(0.97) | LDD1661 | [10] |
LDCM0459 | CL67 | HEK-293T | C115(0.99); C359(1.13); C385(1.08); C260(1.20) | LDD1662 | [10] |
LDCM0460 | CL68 | HEK-293T | C115(1.11); C359(1.10); C385(1.81); C260(0.70) | LDD1663 | [10] |
LDCM0461 | CL69 | HEK-293T | C115(0.96); C359(0.96); C385(1.65); C260(0.91) | LDD1664 | [10] |
LDCM0462 | CL7 | HEK-293T | C115(0.91); C359(1.07); C385(1.07); C260(1.00) | LDD1665 | [10] |
LDCM0463 | CL70 | HEK-293T | C115(1.08); C359(0.90); C385(1.28); C260(0.91) | LDD1666 | [10] |
LDCM0464 | CL71 | HEK-293T | C115(0.95); C359(1.02); C385(1.69); C260(0.89) | LDD1667 | [10] |
LDCM0465 | CL72 | HEK-293T | C115(1.12); C359(0.95); C385(1.19); C260(0.98) | LDD1668 | [10] |
LDCM0466 | CL73 | HEK-293T | C115(0.98); C359(1.04); C385(1.02); C260(1.17) | LDD1669 | [10] |
LDCM0467 | CL74 | HEK-293T | C115(1.01); C359(1.28); C385(0.98); C260(0.98) | LDD1670 | [10] |
LDCM0469 | CL76 | HEK-293T | C115(0.96); C359(1.22); C385(1.13); C260(1.04) | LDD1672 | [10] |
LDCM0470 | CL77 | HEK-293T | C115(0.91); C359(1.58); C385(1.15); C260(1.25) | LDD1673 | [10] |
LDCM0471 | CL78 | HEK-293T | C115(0.93); C359(0.94); C385(1.01) | LDD1674 | [10] |
LDCM0472 | CL79 | HEK-293T | C115(0.99); C359(1.00); C385(1.05); C260(0.95) | LDD1675 | [10] |
LDCM0473 | CL8 | HEK-293T | C115(0.92); C359(0.94); C385(1.91); C260(1.14) | LDD1676 | [10] |
LDCM0474 | CL80 | HEK-293T | C115(1.08); C359(0.99); C385(1.59); C260(0.98) | LDD1677 | [10] |
LDCM0475 | CL81 | HEK-293T | C115(0.92); C359(1.02); C385(1.64); C260(0.98) | LDD1678 | [10] |
LDCM0476 | CL82 | HEK-293T | C115(1.04); C359(0.91); C385(1.36); C260(1.04) | LDD1679 | [10] |
LDCM0477 | CL83 | HEK-293T | C115(1.05); C359(1.02); C385(1.75); C260(0.95) | LDD1680 | [10] |
LDCM0478 | CL84 | HEK-293T | C115(1.02); C359(1.03); C385(1.38); C260(0.88) | LDD1681 | [10] |
LDCM0479 | CL85 | HEK-293T | C115(0.99); C359(1.06); C385(0.88); C260(1.07) | LDD1682 | [10] |
LDCM0480 | CL86 | HEK-293T | C115(1.00); C359(1.06); C385(0.98); C260(1.08) | LDD1683 | [10] |
LDCM0481 | CL87 | HEK-293T | C115(1.03); C359(1.13); C385(0.97); C260(1.12) | LDD1684 | [10] |
LDCM0482 | CL88 | HEK-293T | C115(0.93); C359(1.15); C385(1.05); C260(1.08) | LDD1685 | [10] |
LDCM0483 | CL89 | HEK-293T | C115(1.07); C359(1.39); C385(0.94); C260(1.09) | LDD1686 | [10] |
LDCM0484 | CL9 | HEK-293T | C115(0.93); C359(0.96); C385(2.07); C260(1.11) | LDD1687 | [10] |
LDCM0485 | CL90 | HEK-293T | C115(0.78); C359(0.95); C385(1.18) | LDD1688 | [10] |
LDCM0486 | CL91 | HEK-293T | C115(1.04); C359(1.16); C385(0.66); C260(1.02) | LDD1689 | [10] |
LDCM0487 | CL92 | HEK-293T | C115(0.95); C359(1.01); C385(1.54); C260(1.02) | LDD1690 | [10] |
LDCM0488 | CL93 | HEK-293T | C115(0.92); C359(1.20); C385(1.54); C260(0.95) | LDD1691 | [10] |
LDCM0489 | CL94 | HEK-293T | C115(1.21); C359(1.00); C385(1.27); C260(1.03) | LDD1692 | [10] |
LDCM0490 | CL95 | HEK-293T | C115(0.85); C359(1.16); C385(1.69); C260(1.40) | LDD1693 | [10] |
LDCM0491 | CL96 | HEK-293T | C115(0.96); C359(1.03); C385(1.07); C260(0.87) | LDD1694 | [10] |
LDCM0492 | CL97 | HEK-293T | C115(0.97); C359(0.94); C385(1.02); C260(1.19) | LDD1695 | [10] |
LDCM0493 | CL98 | HEK-293T | C115(0.98); C359(1.01); C385(1.02); C260(0.98) | LDD1696 | [10] |
LDCM0494 | CL99 | HEK-293T | C115(0.95); C359(1.02); C385(0.92); C260(1.07) | LDD1697 | [10] |
LDCM0495 | E2913 | HEK-293T | C115(1.08); C359(1.16); C385(1.11); C260(1.14) | LDD1698 | [10] |
LDCM0468 | Fragment33 | HEK-293T | C115(0.98); C359(1.00); C385(1.00); C260(1.05) | LDD1671 | [10] |
LDCM0427 | Fragment51 | HEK-293T | C115(0.98); C359(0.96); C385(1.09); C260(0.91) | LDD1631 | [10] |
LDCM0022 | KB02 | HEK-293T | C115(1.09); C385(0.89); C260(0.88); C359(1.08) | LDD1492 | [10] |
LDCM0023 | KB03 | HEK-293T | C115(1.04); C385(1.03); C260(0.95); C359(1.04) | LDD1497 | [10] |
LDCM0024 | KB05 | IGR37 | C115(2.27) | LDD3314 | [3] |
LDCM0509 | N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide | MDA-MB-231 | C115(1.30) | LDD2102 | [4] |
LDCM0496 | Nucleophilic fragment 11a | MDA-MB-231 | C115(1.13) | LDD2089 | [4] |
LDCM0497 | Nucleophilic fragment 11b | MDA-MB-231 | C115(1.34) | LDD2090 | [4] |
LDCM0516 | Nucleophilic fragment 21a | MDA-MB-231 | C115(0.58) | LDD2109 | [4] |
LDCM0526 | Nucleophilic fragment 26a | MDA-MB-231 | C115(1.78) | LDD2119 | [4] |
LDCM0535 | Nucleophilic fragment 30b | MDA-MB-231 | C115(1.07) | LDD2128 | [4] |
LDCM0543 | Nucleophilic fragment 38 | MDA-MB-231 | C115(0.88) | LDD2136 | [4] |
LDCM0211 | Nucleophilic fragment 3b | MDA-MB-231 | C115(1.02) | LDD1700 | [4] |
LDCM0547 | Nucleophilic fragment 41 | MDA-MB-231 | C115(0.55) | LDD2141 | [4] |
LDCM0549 | Nucleophilic fragment 43 | MDA-MB-231 | C115(0.83) | LDD2143 | [4] |
LDCM0553 | Nucleophilic fragment 6b | MDA-MB-231 | C115(2.87) | LDD2147 | [4] |
LDCM0556 | Nucleophilic fragment 8a | MDA-MB-231 | C115(0.42) | LDD2150 | [4] |
LDCM0559 | Nucleophilic fragment 9b | MDA-MB-231 | C115(2.09) | LDD2153 | [4] |
The Interaction Atlas With This Target
The Protein(s) Related To This Target
Enzyme
Transporter and channel
GPCR
Protein name | Family | Uniprot ID | |||
---|---|---|---|---|---|
C-X-C chemokine receptor type 3 (CXCR3) | G-protein coupled receptor 1 family | P49682 |
Immunoglobulin
Protein name | Family | Uniprot ID | |||
---|---|---|---|---|---|
Amphoterin-induced protein 1 (AMIGO1) | AMIGO family | Q86WK6 | |||
B-cell antigen receptor complex-associated protein alpha chain (CD79A) | . | P11912 |
Cytokine and receptor
Protein name | Family | Uniprot ID | |||
---|---|---|---|---|---|
Interleukin-3 receptor subunit alpha (IL3RA) | Type I cytokine receptor family | P26951 |
Other
References