Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C242 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 21.9 | ||||
| LDTP12013 | dCTP pyrophosphatase 1 (DCTPP1) | 20.7 | ||||
| LDTP01333 | Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) | 14.6 | ||||
| LDTP04211 | Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) | 13.7 | ||||
| LDTP12628 | Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) | 11.5 | ||||
| LDTP13751 | Exonuclease 1 (EXO1) | 10.6 | ||||
| LDTP06375 | Delta(24)-sterol reductase (DHCR24) | 9.6 | ||||
| LDTP01982 | NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) | 7.7 | ||||
| LDTP04246 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) | 6.4 | ||||
| LDTP03540 | Heme oxygenase 2 (HMOX2) | 6.3 | ||||
| LDTP00032 | 2-hydroxyacyl-CoA lyase 2 (ILVBL) | 6.1 | ||||
| LDTP04285 | Proteasome subunit beta type-2 (PSMB2) | 6.1 | ||||
| LDTP04051 | Nicotinamide phosphoribosyltransferase (NAMPT) | 5.9 | ||||
| LDTP05408 | Antigen peptide transporter 1 (TAP1) | 5.1 | ||||
| LDTP12363 | Lysophosphatidic acid phosphatase type 6 (ACP6) | 5.1 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP10958 | Sigma non-opioid intracellular receptor 1 (SIGMAR1) | 12.6 | ||||
| LDTP09547 | Scavenger receptor class B member 1 (SCARB1) | 7.8 | ||||
| LDTP05900 | Metaxin-1 (MTX1) | 7.1 | ||||
| LDTP18153 | Major facilitator superfamily domain-containing protein 3 (MFSD3) | 7.0 | ||||
| LDTP11813 | Solute carrier family 25 member 32 (SLC25A32) | 7.0 | ||||
| LDTP00562 | Membrane-associated progesterone receptor component 2 (PGRMC2) | 6.9 | ||||
| LDTP05384 | Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) | 6.9 | ||||
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 6.6 | ||||
| LDTP02724 | Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) | 6.4 | ||||
| LDTP11095 | Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) | 6.1 | ||||
| LDTP06034 | Lysosome membrane protein 2 (SCARB2) | 5.6 | ||||
| LDTP17362 | Magnesium transporter NIPA3 (NIPAL1) | 5.4 | ||||
| LDTP06945 | Sigma intracellular receptor 2 (TMEM97) | 5.3 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP11076 | Apolipoprotein L2 (APOL2) | 11.4 | ||||
| LDTP00105 | Protein unc-119 homolog B (UNC119B) | 7.8 | ||||
| LDTP15623 | Neuferricin (CYB5D2) | 7.1 | ||||
| LDTP15067 | Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) | 6.5 | ||||
| LDTP12565 | Mitochondrial import receptor subunit TOM22 homolog (TOMM22) | 6.0 | ||||
| LDTP08081 | Hepatoma-derived growth factor-related protein 2 (HDGFL2) | 5.8 | ||||
| LDTP04241 | Nuclear autoantigenic sperm protein (NASP) | 5.5 | ||||
| LDTP14486 | Clustered mitochondria protein homolog (CLUH) | 5.0 | ||||
| LDTP06391 | Protein transport protein Sec23B (SEC23B) | 5.0 | ||||