General Information of Experiment

Probe Name WYneC  Probe Info 
Probe concentration 10 uM
Criteria Qualitation: Labeling site identification
Quantitative Method
Isotope tag
In Vivo Experiment Model Model Type Cell lysate
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cell lysate (HEK-293T)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 43 Protein Related to This Bioclass
Target ID Target Name Binding Sites
 LDTP02522  60 kDa heat shock protein, mitochondrial (HSPD1) C447
 LDTP00912  Aldo-keto reductase family 1 member B10 (AKR1B10) C187
 LDTP04561  ATP-citrate synthase (ACLY) C20
 LDTP05550  ATP-dependent RNA helicase A (DHX9) C438
 LDTP02831  Carbonyl reductase [NADPH] 1 (CBR1) C150
 LDTP02001  Catalase (CAT) C460
 LDTP02001  Catalase (CAT) C232
 LDTP01341  Cytosolic 10-formyltetrahydrofolate dehydrogenase (ALDH1L1) C662
 LDTP05136  DNA-dependent protein kinase catalytic subunit (PRKDC) C1312
 LDTP02672  Elongation factor 2 (EEF2) C41
 LDTP04243  Fatty acid synthase (FASN) C2202
 LDTP02008  Fructose-bisphosphate aldolase A (ALDOA) C339
 LDTP02328  Gamma-enolase (ENO2) C357
 LDTP01768  Glutamate dehydrogenase 1, mitochondrial (GLUD1) C172
 LDTP04185  Glutamate--cysteine ligase catalytic subunit (GCLC) C501
 LDTP02038  Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) C156
 LDTP02038  Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) C152
 LDTP02038  Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) C247
 LDTP02552  Glycogen phosphorylase, brain form (PYGB) C326
 LDTP05007  GTP-binding nuclear protein Ran (RAN) C120
 LDTP05007  GTP-binding nuclear protein Ran (RAN) C112
 LDTP12687  Guanine nucleotide-binding protein-like 3-like protein (GNL3L) C278
 LDTP02541  Heat shock cognate 71 kDa protein (HSPA8) C603
 LDTP01766  L-lactate dehydrogenase A chain (LDHA) C163
 LDTP02179  L-lactate dehydrogenase B chain (LDHB) C164
 LDTP02385  Leukotriene A-4 hydrolase (LTA4H) C147
 LDTP02506  Microsomal glutathione S-transferase 1 (MGST1) C50
 LDTP03764  Myosin-9 (MYH9) C671
 LDTP03764  Myosin-9 (MYH9) C988
 LDTP05372  Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) C107
 LDTP01787  Phosphoglycerate kinase 1 (PGK1) C367
 LDTP02733  Pyruvate kinase PKM (PKM) C49
 LDTP04877  Ras-related C3 botulinum toxin substrate 3 (RAC3) C157
 LDTP04877  Ras-related C3 botulinum toxin substrate 3 (RAC3) C178
 LDTP04877  Ras-related C3 botulinum toxin substrate 3 (RAC3) C6
 LDTP05006  Ras-related protein Rab-1A (RAB1A) C126
 LDTP01127  Rho-associated protein kinase 2 (ROCK2) C804
 LDTP01127  Rho-associated protein kinase 2 (ROCK2) C649
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) C447
 LDTP04392  Sodium/potassium-transporting ATPase subunit alpha-2 (ATP1A2) C660
 LDTP04851  Triosephosphate isomerase (TPI1) C67
 LDTP04074  Ubiquitin carboxyl-terminal hydrolase 5 (USP5) C838
 LDTP02383  Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCHL1) C152
Transporter and channel
Click to Show/Hide to Show 10 Protein Related to This Bioclass
Target ID Target Name Binding Sites
 LDTP02199  Annexin A2 (ANXA2) C9
 LDTP05252  Clathrin heavy chain 1 (CLTC) C870
 LDTP03107  Filamin-A (FLNA) C1157
 LDTP03107  Filamin-A (FLNA) C2543
 LDTP01197  Filamin-B (FLNB) C2333
 LDTP01197  Filamin-B (FLNB) C1617
 LDTP01197  Filamin-B (FLNB) C2431
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) C129
 LDTP14031  Talin-1 (TLN1) C1199
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) C47
Other
Click to Show/Hide to Show 50 Protein Related to This Bioclass
Target ID Target Name Binding Sites
 LDTP05294  Adenylyl cyclase-associated protein 1 (CAP1) C93
 LDTP05294  Adenylyl cyclase-associated protein 1 (CAP1) C375
 LDTP02631  Alpha-actinin-1 (ACTN1) C480
 LDTP13464  CASP8-associated protein 2 (CASP8AP2) C1240
 LDTP03665  Cleavage stimulation factor subunit 2 (CSTF2) C150
 LDTP14486  Clustered mitochondria protein homolog (CLUH) C1196
 LDTP03244  Cofilin-1 (CFL1) C139
 LDTP07613  Complexin-2 (CPLX2) C90
 LDTP13580  Coronin-1C (CORO1C) C420
 LDTP13580  Coronin-1C (CORO1C) C190
 LDTP04887  Destrin (DSTN) C23
 LDTP04887  Destrin (DSTN) C135
 LDTP02101  Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) C218
 LDTP06055  Eukaryotic translation initiation factor 3 subunit A (EIF3A) C478
 LDTP10078  Far upstream element-binding protein 1 (FUBP1) C148
 LDTP02341  Galectin-1 (LGALS1) C61
 LDTP01048  General vesicular transport factor p115 (USO1) C303
 LDTP04621  Heat shock-related 70 kDa protein 2 (HSPA2) C606
 LDTP03615  Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) C34
 LDTP12571  LanC-like protein 2 (LANCL2) C169
 LDTP05360  Large ribosomal subunit protein eL20 (RPL18A) C22
 LDTP04990  Large ribosomal subunit protein eL8 (RPL7A) C199
 LDTP02109  Large ribosomal subunit protein uL10 (RPLP0) C119
 LDTP02109  Large ribosomal subunit protein uL10 (RPLP0) C27
 LDTP03517  Large ribosomal subunit protein uL11 (RPL12) C141
 LDTP03517  Large ribosomal subunit protein uL11 (RPL12) C17
 LDTP05008  Large ribosomal subunit protein uL14 (RPL23) C125
 LDTP03404  Microtubule-associated protein 4 (MAP4) C635
 LDTP14136  Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13) C50
 LDTP06366  Poly(rC)-binding protein 1 (PCBP1) C109
 LDTP02218  Profilin-1 (PFN1) C128
 LDTP13519  Proteasome activator complex subunit 2 (PSME2) C91
 LDTP03574  Rab GDP dissociation inhibitor alpha (GDI1) C317
 LDTP10834  RUN and FYVE domain-containing protein 1 (RUFY1) C351
 LDTP05898  Sequestosome-1 (SQSTM1) C113
 LDTP13991  Serine-threonine kinase receptor-associated protein (STRAP) C305
 LDTP04982  Small nuclear ribonucleoprotein Sm D2 (SNRPD2) C63
 LDTP04913  Small ribosomal subunit protein eS1 (RPS3A) C96
 LDTP02302  Small ribosomal subunit protein eS17 (RPS17) C35
 LDTP02312  Small ribosomal subunit protein uS2 (RPSA) C148
 LDTP06094  Src substrate cortactin (CTTN) C112
 LDTP06094  Src substrate cortactin (CTTN) C246
 LDTP02205  Tubulin beta chain (TUBB) C12
 LDTP02205  Tubulin beta chain (TUBB) C354
 LDTP05904  Tubulin beta-3 chain (TUBB3) C12
 LDTP05076  Tubulin beta-4B chain (TUBB4B) C354
 LDTP05034  Ubiquitin-ribosomal protein eL40 fusion protein (UBA52) C115
 LDTP02297  Vimentin (VIM) C328
 LDTP02946  Vinculin (VCL) C313
 LDTP08018  Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) C272

References

1 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764