General Information of Experiment

Probe Name Alkylaryl probe 2  Probe Info 
Probe concentration 1 mM
Criteria Quantification: Probe vs DMSO
Quantitative Method
SILAC
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 29 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00968  Acyl-CoA (8-3)-desaturase (FADS1) 20.0
 LDTP01699  Acyl-CoA 6-desaturase (FADS2) 20.0
 LDTP03540  Heme oxygenase 2 (HMOX2) 20.0
 LDTP13703  Histone lysine demethylase PHF8 (PHF8) 20.0
 LDTP00957  Lysine-specific histone demethylase 1A (KDM1A) 20.0
 LDTP01005  Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3) 20.0
 LDTP05967  Nucleic acid dioxygenase ALKBH1 (ALKBH1) 20.0
 LDTP02918  S-adenosylmethionine decarboxylase proenzyme (AMD1) 20.0
 LDTP15725  Secernin-2 (SCRN2) 20.0
 LDTP00344  Stearoyl-CoA desaturase (SCD) 20.0
 LDTP12420  Xaa-Pro aminopeptidase 3 (XPNPEP3) 20.0
 LDTP03939  Lysine-specific demethylase 5C (KDM5C) 19.0
 LDTP06307  Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) 19.0
 LDTP10215  Carboxymethylenebutenolidase homolog (CMBL) 18.0
 LDTP09043  Lysine-specific histone demethylase 2 (KDM1B) 17.0
 LDTP18414  5'-nucleotidase domain-containing protein 2 (NT5DC2) 16.0
 LDTP17022  Secernin-3 (SCRN3) 15.0
 LDTP02386  Fructose-bisphosphate aldolase C (ALDOC) 14.0
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 14.0
 LDTP11595  Alpha-ketoglutarate-dependent dioxygenase FTO (FTO) 13.0
 LDTP03592  Ribonucleoside-diphosphate reductase subunit M2 (RRM2) 13.0
 LDTP02008  Fructose-bisphosphate aldolase A (ALDOA) 12.0
 LDTP03560  Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) 11.0
 LDTP02074  Aldehyde dehydrogenase, mitochondrial (ALDH2) 11.0
 LDTP07979  FAST kinase domain-containing protein 5, mitochondrial (FASTKD5) 10.0
 LDTP07110  Putative transferase CAF17, mitochondrial (IBA57) 9.0
 LDTP08451  Ribosomal oxygenase 2 (RIOX2) 8.0
 LDTP08476  5'-3' exonuclease PLD3 (PLD3) 5.0
 LDTP12803  Dipeptidyl peptidase 3 (DPP3) 5.0
Transporter and channel
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP05231  Cytochrome c (CYCS) 7.0
Transcription factor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP09932  SWI/SNF complex subunit SMARCC1 (SMARCC1) 5.0
Other
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP19372  Tetratricopeptide repeat protein 38 (TTC38) 14.0
 LDTP14085  Protein PRRC2C (PRRC2C) 5.0

References

1 Hydrazines as versatile chemical biology probes and drug-discovery tools for cofactor-dependent enzymes. bioRxiv, 2020-06.