Details of the Target

General Information of Target

Target ID LDTP16962
Target Name Melanoma-associated antigen B1 (MAGEB1)
Gene Name MAGEB1
Gene ID 4112
Synonyms
MAGEL1; MAGEXP; Melanoma-associated antigen B1; Cancer/testis antigen 3.1; CT3.1; DSS-AHC critical interval MAGE superfamily 10; DAM10; MAGE-B1 antigen; MAGE-XP antigen
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSLEQRSPHCKPDEDLEAQGEDLGLMGAQEPTGEEEETTSSSDSKEEEVSAAGSSSPPQS
PQGGASSSISVYYTLWSQFDEGSSSQEEEEPSSSVDPAQLEFMFQEALKLKVAELVHFLL
HKYRVKEPVTKAEMLESVIKNYKRYFPVIFGKASEFMQVIFGTDVKEVDPAGHSYILVTA
LGLSCDSMLGDGHSMPKAALLIIVLGVILTKDNCAPEEVIWEALSVMGVYVGKEHMFYGE
PRKLLTQDWVQENYLEYRQVPGSDPAHYEFLWGSKAHAETSYEKVINYLVMLNAREPICY
PSLYEEVLGEEQEGV
Target Bioclass
Other
Uniprot ID
P43366
Ensemble ID
ENST00000378981.8
HGNC ID
HGNC:6808

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C206(0.00); C8(0.00); C147(0.00); C715(0.00)  LDD0161  [1]
PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FFF probe11
 Probe Info  		10.25  LDD0472  [2]
FFF probe3
 Probe Info  		17.58  LDD0465  [2]

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
2 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.