Details of the Target
General Information of Target
Target ID | LDTP03960 | |||||
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Target Name | Protein kinase C iota type (PRKCI) | |||||
Gene Name | PRKCI | |||||
Gene ID | 5584 | |||||
Synonyms |
DXS1179E; Protein kinase C iota type; EC 2.7.11.13; Atypical protein kinase C-lambda/iota; PRKC-lambda/iota; aPKC-lambda/iota; nPKC-iota |
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3D Structure | ||||||
Sequence |
MPTQRDSSTMSHTVAGGGSGDHSHQVRVKAYYRGDIMITHFEPSISFEGLCNEVRDMCSF
DNEQLFTMKWIDEEGDPCTVSSQLELEEAFRLYELNKDSELLIHVFPCVPERPGMPCPGE DKSIYRRGARRWRKLYCANGHTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHK KCHKLVTIECGRHSLPQEPVMPMDQSSMHSDHAQTVIPYNPSSHESLDQVGEEKEAMNTR ESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQ TEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSA EISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYI APEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIR IPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFK PNISGEFGLDNFDSQFTNEPVQLTPDDDDIVRKIDQSEFEGFEYINPLLMSAEECV |
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Target Type |
Literature-reported
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Target Bioclass |
Enzyme
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Family |
Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily
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Subcellular location |
Cytoplasm
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Function |
Calcium- and diacylglycerol-independent serine/ threonine-protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation of microtubule dynamics in the early secretory pathway. Is necessary for BCR-ABL oncogene-mediated resistance to apoptotic drug in leukemia cells, protecting leukemia cells against drug-induced apoptosis. In cultured neurons, prevents amyloid beta protein-induced apoptosis by interrupting cell death process at a very early step. In glioblastoma cells, may function downstream of phosphatidylinositol 3-kinase (PI(3)K) and PDPK1 in the promotion of cell survival by phosphorylating and inhibiting the pro-apoptotic factor BAD. Can form a protein complex in non-small cell lung cancer (NSCLC) cells with PARD6A and ECT2 and regulate ECT2 oncogenic activity by phosphorylation, which in turn promotes transformed growth and invasion. In response to nerve growth factor (NGF), acts downstream of SRC to phosphorylate and activate IRAK1, allowing the subsequent activation of NF-kappa-B and neuronal cell survival. Functions in the organization of the apical domain in epithelial cells by phosphorylating EZR. This step is crucial for activation and normal distribution of EZR at the early stages of intestinal epithelial cell differentiation. Forms a protein complex with LLGL1 and PARD6B independently of PARD3 to regulate epithelial cell polarity. Plays a role in microtubule dynamics in the early secretory pathway through interaction with RAB2A and GAPDH and recruitment to vesicular tubular clusters (VTCs). In human coronary artery endothelial cells (HCAEC), is activated by saturated fatty acids and mediates lipid-induced apoptosis. Involved in early synaptic long term potentiation phase in CA1 hippocampal cells and short term memory formation.
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TTD ID | ||||||
Uniprot ID | ||||||
DrugMap ID | ||||||
Ensemble ID | ||||||
HGNC ID | ||||||
ChEMBL ID |
Probe(s) Labeling This Target
ABPP Probe
Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
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m-APA Probe Info |
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13.25 | LDD0402 | [1] | |
STPyne Probe Info |
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K170(6.67); K29(6.27); K488(7.63); K494(5.56) | LDD0277 | [2] | |
Probe 1 Probe Info |
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Y93(77.18) | LDD3495 | [3] | |
BTD Probe Info |
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C137(1.24) | LDD2094 | [4] | |
AHL-Pu-1 Probe Info |
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C117(19.39) | LDD0170 | [5] | |
DBIA Probe Info |
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C154(0.92); C157(0.92) | LDD0078 | [6] | |
ATP probe Probe Info |
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K380(0.00); K488(0.00); K184(0.00) | LDD0199 | [7] | |
4-Iodoacetamidophenylacetylene Probe Info |
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C190(0.00); C51(0.00); C137(0.00) | LDD0038 | [8] | |
IA-alkyne Probe Info |
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N.A. | LDD0032 | [9] | |
Lodoacetamide azide Probe Info |
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C51(0.00); C507(0.00); C400(0.00); C137(0.00) | LDD0037 | [8] | |
NAIA_4 Probe Info |
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N.A. | LDD2226 | [10] | |
WYneN Probe Info |
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N.A. | LDD0021 | [11] | |
IPM Probe Info |
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C117(0.00); C108(0.00); C400(0.00); C51(0.00) | LDD2156 | [12] | |
TFBX Probe Info |
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N.A. | LDD0148 | [13] | |
Acrolein Probe Info |
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H22(0.00); C190(0.00); C400(0.00) | LDD0217 | [14] | |
Methacrolein Probe Info |
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N.A. | LDD0218 | [14] | |
W1 Probe Info |
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N.A. | LDD0236 | [15] | |
AOyne Probe Info |
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12.10 | LDD0443 | [16] | |
NAIA_5 Probe Info |
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C51(0.00); C400(0.00); C507(0.00); C321(0.00) | LDD2223 | [10] |
PAL-AfBPP Probe
Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
---|---|---|---|---|---|
STS-1 Probe Info |
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1.25 | LDD0137 | [17] | |
STS-2 Probe Info |
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N.A. | LDD0138 | [17] | |
VE-P Probe Info |
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N.A. | LDD0396 | [18] |
Competitor(s) Related to This Target
Competitor ID | Name | Cell line | Binding Site(Ratio) | Interaction ID | Ref |
---|---|---|---|---|---|
LDCM0524 | 2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide | MDA-MB-231 | C154(0.86) | LDD2117 | [4] |
LDCM0558 | 2-Cyano-N-phenylacetamide | MDA-MB-231 | C154(1.61) | LDD2152 | [4] |
LDCM0025 | 4SU-RNA | DM93 | C117(19.39) | LDD0170 | [5] |
LDCM0026 | 4SU-RNA+native RNA | DM93 | C117(5.92) | LDD0171 | [5] |
LDCM0214 | AC1 | HCT 116 | C108(0.96); C117(0.96); C400(1.22); C507(1.47) | LDD0531 | [6] |
LDCM0215 | AC10 | HCT 116 | C108(1.06); C117(1.06); C400(1.02); C507(0.98) | LDD0532 | [6] |
LDCM0216 | AC100 | HCT 116 | C400(0.86); C507(1.17) | LDD0533 | [6] |
LDCM0217 | AC101 | HCT 116 | C400(0.82); C507(0.82) | LDD0534 | [6] |
LDCM0218 | AC102 | HCT 116 | C400(1.03); C507(0.78) | LDD0535 | [6] |
LDCM0219 | AC103 | HCT 116 | C400(0.98); C507(0.78) | LDD0536 | [6] |
LDCM0220 | AC104 | HCT 116 | C400(1.01); C507(0.87) | LDD0537 | [6] |
LDCM0221 | AC105 | HCT 116 | C400(0.81); C507(0.73) | LDD0538 | [6] |
LDCM0222 | AC106 | HCT 116 | C400(0.94); C507(0.97) | LDD0539 | [6] |
LDCM0223 | AC107 | HCT 116 | C400(0.97); C507(0.41) | LDD0540 | [6] |
LDCM0224 | AC108 | HCT 116 | C400(0.92); C507(1.62) | LDD0541 | [6] |
LDCM0225 | AC109 | HCT 116 | C400(0.92); C507(1.59) | LDD0542 | [6] |
LDCM0226 | AC11 | HCT 116 | C108(1.04); C117(1.04); C400(1.10); C507(1.01) | LDD0543 | [6] |
LDCM0227 | AC110 | HCT 116 | C400(0.81); C507(1.89) | LDD0544 | [6] |
LDCM0228 | AC111 | HCT 116 | C400(0.80); C507(1.21) | LDD0545 | [6] |
LDCM0229 | AC112 | HCT 116 | C400(0.76); C507(0.79) | LDD0546 | [6] |
LDCM0230 | AC113 | HCT 116 | C108(1.04); C117(1.04); C400(1.16); C507(1.10) | LDD0547 | [6] |
LDCM0231 | AC114 | HCT 116 | C108(1.03); C117(1.03); C400(1.11); C507(0.97) | LDD0548 | [6] |
LDCM0232 | AC115 | HCT 116 | C108(1.14); C117(1.14); C400(0.98); C507(0.88) | LDD0549 | [6] |
LDCM0233 | AC116 | HCT 116 | C108(0.98); C117(0.98); C400(1.00); C507(0.99) | LDD0550 | [6] |
LDCM0234 | AC117 | HCT 116 | C108(1.11); C117(1.11); C400(1.18); C507(0.96) | LDD0551 | [6] |
LDCM0235 | AC118 | HCT 116 | C108(0.88); C117(0.88); C400(1.17); C507(1.10) | LDD0552 | [6] |
LDCM0236 | AC119 | HCT 116 | C108(0.98); C117(0.98); C400(1.07); C507(0.99) | LDD0553 | [6] |
LDCM0237 | AC12 | HCT 116 | C108(1.07); C117(1.07); C400(1.10); C507(1.45) | LDD0554 | [6] |
LDCM0238 | AC120 | HCT 116 | C108(0.90); C117(0.90); C400(1.15); C507(1.15) | LDD0555 | [6] |
LDCM0239 | AC121 | HCT 116 | C108(0.96); C117(0.96); C400(1.06); C507(1.03) | LDD0556 | [6] |
LDCM0240 | AC122 | HCT 116 | C108(1.34); C117(1.34); C400(1.08); C507(0.84) | LDD0557 | [6] |
LDCM0241 | AC123 | HCT 116 | C108(0.97); C117(0.97); C400(1.01); C507(1.09) | LDD0558 | [6] |
LDCM0242 | AC124 | HCT 116 | C108(1.01); C117(1.01); C400(1.17); C507(1.13) | LDD0559 | [6] |
LDCM0243 | AC125 | HCT 116 | C108(1.04); C117(1.04); C400(1.12); C507(1.01) | LDD0560 | [6] |
LDCM0244 | AC126 | HCT 116 | C108(1.14); C117(1.14); C400(0.96); C507(1.02) | LDD0561 | [6] |
LDCM0245 | AC127 | HCT 116 | C108(0.95); C117(0.95); C400(1.17); C507(1.10) | LDD0562 | [6] |
LDCM0246 | AC128 | HCT 116 | C400(0.97) | LDD0563 | [6] |
LDCM0247 | AC129 | HCT 116 | C400(1.05) | LDD0564 | [6] |
LDCM0249 | AC130 | HCT 116 | C400(0.98) | LDD0566 | [6] |
LDCM0250 | AC131 | HCT 116 | C400(0.96) | LDD0567 | [6] |
LDCM0251 | AC132 | HCT 116 | C400(1.06) | LDD0568 | [6] |
LDCM0252 | AC133 | HCT 116 | C400(1.00) | LDD0569 | [6] |
LDCM0253 | AC134 | HCT 116 | C400(0.92) | LDD0570 | [6] |
LDCM0254 | AC135 | HCT 116 | C400(0.85) | LDD0571 | [6] |
LDCM0255 | AC136 | HCT 116 | C400(0.97) | LDD0572 | [6] |
LDCM0256 | AC137 | HCT 116 | C400(1.04) | LDD0573 | [6] |
LDCM0257 | AC138 | HCT 116 | C400(0.78) | LDD0574 | [6] |
LDCM0258 | AC139 | HCT 116 | C400(0.98) | LDD0575 | [6] |
LDCM0259 | AC14 | HCT 116 | C108(1.15); C117(1.15); C400(1.05); C507(1.08) | LDD0576 | [6] |
LDCM0260 | AC140 | HCT 116 | C400(0.80) | LDD0577 | [6] |
LDCM0261 | AC141 | HCT 116 | C400(0.84) | LDD0578 | [6] |
LDCM0262 | AC142 | HCT 116 | C400(1.00) | LDD0579 | [6] |
LDCM0263 | AC143 | HCT 116 | C400(0.91); C507(0.93) | LDD0580 | [6] |
LDCM0264 | AC144 | HCT 116 | C400(0.80); C507(1.16) | LDD0581 | [6] |
LDCM0265 | AC145 | HCT 116 | C400(0.89); C507(1.09) | LDD0582 | [6] |
LDCM0266 | AC146 | HCT 116 | C400(0.93); C507(1.02) | LDD0583 | [6] |
LDCM0267 | AC147 | HCT 116 | C400(0.72); C507(1.07) | LDD0584 | [6] |
LDCM0268 | AC148 | HCT 116 | C400(0.71); C507(2.17) | LDD0585 | [6] |
LDCM0269 | AC149 | HCT 116 | C400(0.81); C507(1.60) | LDD0586 | [6] |
LDCM0270 | AC15 | HCT 116 | C108(0.99); C117(0.99); C400(1.03); C507(1.12) | LDD0587 | [6] |
LDCM0271 | AC150 | HCT 116 | C400(0.93); C507(1.13) | LDD0588 | [6] |
LDCM0272 | AC151 | HCT 116 | C400(0.92); C507(1.26) | LDD0589 | [6] |
LDCM0273 | AC152 | HCT 116 | C400(0.78); C507(1.18) | LDD0590 | [6] |
LDCM0274 | AC153 | HCT 116 | C400(0.88); C507(1.64) | LDD0591 | [6] |
LDCM0621 | AC154 | HCT 116 | C400(0.94); C507(1.12) | LDD2158 | [6] |
LDCM0622 | AC155 | HCT 116 | C400(0.93); C507(1.39) | LDD2159 | [6] |
LDCM0623 | AC156 | HCT 116 | C400(1.03); C507(0.96) | LDD2160 | [6] |
LDCM0624 | AC157 | HCT 116 | C400(0.97); C507(1.55) | LDD2161 | [6] |
LDCM0276 | AC17 | HCT 116 | C108(0.87); C117(0.87); C507(0.88); C400(1.00) | LDD0593 | [6] |
LDCM0277 | AC18 | HCT 116 | C507(1.00); C400(1.04); C108(1.05); C117(1.05) | LDD0594 | [6] |
LDCM0278 | AC19 | HCT 116 | C108(1.00); C117(1.00); C507(1.01); C400(1.10) | LDD0595 | [6] |
LDCM0279 | AC2 | HCT 116 | C108(0.94); C117(0.94); C507(0.98); C400(1.00) | LDD0596 | [6] |
LDCM0280 | AC20 | HCT 116 | C108(0.85); C117(0.85); C400(0.95); C507(1.31) | LDD0597 | [6] |
LDCM0281 | AC21 | HCT 116 | C108(0.76); C117(0.76); C400(0.98); C507(1.07) | LDD0598 | [6] |
LDCM0282 | AC22 | HCT 116 | C108(0.80); C117(0.80); C507(0.96); C400(0.98) | LDD0599 | [6] |
LDCM0283 | AC23 | HCT 116 | C108(0.91); C117(0.91); C507(1.03); C400(1.18) | LDD0600 | [6] |
LDCM0284 | AC24 | HCT 116 | C108(0.92); C117(0.92); C400(1.01); C507(1.15) | LDD0601 | [6] |
LDCM0285 | AC25 | HCT 116 | C108(0.95); C117(0.95); C400(0.96) | LDD0602 | [6] |
LDCM0286 | AC26 | HCT 116 | C400(0.90); C108(0.92); C117(0.92) | LDD0603 | [6] |
LDCM0287 | AC27 | HCT 116 | C400(0.80); C108(0.99); C117(0.99) | LDD0604 | [6] |
LDCM0288 | AC28 | HCT 116 | C400(0.77); C108(0.84); C117(0.84) | LDD0605 | [6] |
LDCM0289 | AC29 | HCT 116 | C400(0.74); C108(0.99); C117(0.99) | LDD0606 | [6] |
LDCM0290 | AC3 | HCT 116 | C108(1.10); C117(1.10); C400(1.14); C507(1.21) | LDD0607 | [6] |
LDCM0291 | AC30 | HCT 116 | C400(0.74); C108(0.88); C117(0.88) | LDD0608 | [6] |
LDCM0292 | AC31 | HCT 116 | C400(0.90); C108(0.91); C117(0.91) | LDD0609 | [6] |
LDCM0293 | AC32 | HCT 116 | C400(0.71); C108(0.91); C117(0.91) | LDD0610 | [6] |
LDCM0294 | AC33 | HCT 116 | C400(0.81); C108(0.94); C117(0.94) | LDD0611 | [6] |
LDCM0295 | AC34 | HCT 116 | C108(0.76); C117(0.76); C400(0.78) | LDD0612 | [6] |
LDCM0296 | AC35 | HCT 116 | C108(0.86); C117(0.86); C400(1.15) | LDD0613 | [6] |
LDCM0297 | AC36 | HCT 116 | C108(1.04); C117(1.04); C400(1.07) | LDD0614 | [6] |
LDCM0298 | AC37 | HCT 116 | C108(0.92); C117(0.92); C400(1.11) | LDD0615 | [6] |
LDCM0299 | AC38 | HCT 116 | C108(1.02); C117(1.02); C400(1.02) | LDD0616 | [6] |
LDCM0300 | AC39 | HCT 116 | C108(0.93); C117(0.93); C400(1.08) | LDD0617 | [6] |
LDCM0301 | AC4 | HCT 116 | C108(1.16); C117(1.16); C400(1.30); C507(1.54) | LDD0618 | [6] |
LDCM0302 | AC40 | HCT 116 | C400(0.91); C108(0.94); C117(0.94) | LDD0619 | [6] |
LDCM0303 | AC41 | HCT 116 | C108(1.02); C117(1.02); C400(1.05) | LDD0620 | [6] |
LDCM0304 | AC42 | HCT 116 | C108(0.91); C117(0.91); C400(0.98) | LDD0621 | [6] |
LDCM0305 | AC43 | HCT 116 | C400(0.94); C108(1.02); C117(1.02) | LDD0622 | [6] |
LDCM0306 | AC44 | HCT 116 | C108(0.94); C117(0.94); C400(0.99) | LDD0623 | [6] |
LDCM0307 | AC45 | HCT 116 | C400(0.89); C108(0.93); C117(0.93) | LDD0624 | [6] |
LDCM0308 | AC46 | HCT 116 | C507(0.70); C400(0.88); C108(1.25); C117(1.25) | LDD0625 | [6] |
LDCM0309 | AC47 | HCT 116 | C507(0.87); C400(1.00); C108(1.44); C117(1.44) | LDD0626 | [6] |
LDCM0310 | AC48 | HCT 116 | C507(0.72); C400(0.86); C108(1.12); C117(1.12) | LDD0627 | [6] |
LDCM0311 | AC49 | HCT 116 | C507(0.64); C400(0.75); C108(1.13); C117(1.13) | LDD0628 | [6] |
LDCM0312 | AC5 | HCT 116 | C108(1.08); C117(1.08); C507(1.19); C400(1.29) | LDD0629 | [6] |
LDCM0313 | AC50 | HCT 116 | C507(0.64); C400(0.79); C108(1.04); C117(1.04) | LDD0630 | [6] |
LDCM0314 | AC51 | HCT 116 | C507(0.68); C400(0.91); C108(1.18); C117(1.18) | LDD0631 | [6] |
LDCM0315 | AC52 | HCT 116 | C507(0.71); C400(0.86); C108(1.17); C117(1.17) | LDD0632 | [6] |
LDCM0316 | AC53 | HCT 116 | C400(0.92); C507(0.95); C108(1.05); C117(1.05) | LDD0633 | [6] |
LDCM0317 | AC54 | HCT 116 | C507(0.84); C400(0.88); C108(1.25); C117(1.25) | LDD0634 | [6] |
LDCM0318 | AC55 | HCT 116 | C400(0.97); C108(0.98); C117(0.98); C507(1.06) | LDD0635 | [6] |
LDCM0319 | AC56 | HCT 116 | C400(0.73); C507(1.00); C108(1.00); C117(1.00) | LDD0636 | [6] |
LDCM0320 | AC57 | HCT 116 | C108(0.98); C117(0.98); C400(1.04); C507(1.07) | LDD0637 | [6] |
LDCM0321 | AC58 | HCT 116 | C108(1.03); C117(1.03); C400(1.03); C507(1.17) | LDD0638 | [6] |
LDCM0322 | AC59 | HCT 116 | C400(0.86); C507(1.07); C108(1.29); C117(1.29) | LDD0639 | [6] |
LDCM0323 | AC6 | HCT 116 | C400(0.86); C108(0.89); C117(0.89); C507(0.97) | LDD0640 | [6] |
LDCM0324 | AC60 | HCT 116 | C400(0.92); C108(1.17); C117(1.17); C507(1.19) | LDD0641 | [6] |
LDCM0325 | AC61 | HCT 116 | C400(0.91); C507(1.00); C108(1.17); C117(1.17) | LDD0642 | [6] |
LDCM0326 | AC62 | HCT 116 | C400(0.90); C507(1.05); C108(1.26); C117(1.26) | LDD0643 | [6] |
LDCM0327 | AC63 | HCT 116 | C507(0.97); C400(1.04); C108(1.14); C117(1.14) | LDD0644 | [6] |
LDCM0328 | AC64 | HCT 116 | C400(0.96); C507(1.02); C108(1.16); C117(1.16) | LDD0645 | [6] |
LDCM0329 | AC65 | HCT 116 | C507(0.80); C400(0.94); C108(1.23); C117(1.23) | LDD0646 | [6] |
LDCM0330 | AC66 | HCT 116 | C400(0.96); C507(1.00); C108(1.14); C117(1.14) | LDD0647 | [6] |
LDCM0331 | AC67 | HCT 116 | C400(0.81); C507(0.83); C108(1.19); C117(1.19) | LDD0648 | [6] |
LDCM0332 | AC68 | HCT 116 | C400(0.85); C108(1.28); C117(1.28) | LDD0649 | [6] |
LDCM0333 | AC69 | HCT 116 | C400(0.92); C108(1.01); C117(1.01) | LDD0650 | [6] |
LDCM0334 | AC7 | HCT 116 | C507(0.86); C108(1.10); C117(1.10); C400(1.13) | LDD0651 | [6] |
LDCM0335 | AC70 | HCT 116 | C108(0.82); C117(0.82); C400(1.07) | LDD0652 | [6] |
LDCM0336 | AC71 | HCT 116 | C400(0.93); C108(1.28); C117(1.28) | LDD0653 | [6] |
LDCM0337 | AC72 | HCT 116 | C400(0.90); C108(1.02); C117(1.02) | LDD0654 | [6] |
LDCM0338 | AC73 | HCT 116 | C108(0.82); C117(0.82); C400(0.83) | LDD0655 | [6] |
LDCM0339 | AC74 | HCT 116 | C108(0.79); C117(0.79); C400(0.98) | LDD0656 | [6] |
LDCM0340 | AC75 | HCT 116 | C108(0.63); C117(0.63); C400(1.07) | LDD0657 | [6] |
LDCM0341 | AC76 | HCT 116 | C400(0.91); C108(0.99); C117(0.99) | LDD0658 | [6] |
LDCM0342 | AC77 | HCT 116 | C400(0.79); C108(0.97); C117(0.97) | LDD0659 | [6] |
LDCM0343 | AC78 | HCT 116 | C400(0.90); C108(1.18); C117(1.18) | LDD0660 | [6] |
LDCM0344 | AC79 | HCT 116 | C400(0.73); C108(1.05); C117(1.05) | LDD0661 | [6] |
LDCM0345 | AC8 | HCT 116 | C507(0.96); C108(1.02); C117(1.02); C400(1.07) | LDD0662 | [6] |
LDCM0346 | AC80 | HCT 116 | C400(0.80); C108(1.05); C117(1.05) | LDD0663 | [6] |
LDCM0347 | AC81 | HCT 116 | C400(1.08); C108(1.31); C117(1.31) | LDD0664 | [6] |
LDCM0348 | AC82 | HCT 116 | C108(0.56); C117(0.56); C400(0.98) | LDD0665 | [6] |
LDCM0349 | AC83 | HCT 116 | C108(0.51); C117(0.51); C400(0.54) | LDD0666 | [6] |
LDCM0350 | AC84 | HCT 116 | C108(0.51); C117(0.51); C400(0.57) | LDD0667 | [6] |
LDCM0351 | AC85 | HCT 116 | C108(0.62); C117(0.62); C400(0.84) | LDD0668 | [6] |
LDCM0352 | AC86 | HCT 116 | C400(0.88); C108(0.96); C117(0.96) | LDD0669 | [6] |
LDCM0353 | AC87 | HCT 116 | C108(0.63); C117(0.63); C400(1.29) | LDD0670 | [6] |
LDCM0354 | AC88 | HCT 116 | C108(0.65); C117(0.65); C400(0.75) | LDD0671 | [6] |
LDCM0355 | AC89 | HCT 116 | C400(0.71); C108(0.84); C117(0.84) | LDD0672 | [6] |
LDCM0357 | AC90 | HCT 116 | C108(0.59); C117(0.59); C400(1.85) | LDD0674 | [6] |
LDCM0358 | AC91 | HCT 116 | C400(0.58); C108(0.99); C117(0.99) | LDD0675 | [6] |
LDCM0359 | AC92 | HCT 116 | C400(0.70); C108(0.74); C117(0.74) | LDD0676 | [6] |
LDCM0360 | AC93 | HCT 116 | C108(0.70); C117(0.70); C400(0.80) | LDD0677 | [6] |
LDCM0361 | AC94 | HCT 116 | C108(0.81); C117(0.81); C400(0.96) | LDD0678 | [6] |
LDCM0362 | AC95 | HCT 116 | C108(0.58); C117(0.58); C400(0.80) | LDD0679 | [6] |
LDCM0363 | AC96 | HCT 116 | C400(0.63); C108(0.80); C117(0.80) | LDD0680 | [6] |
LDCM0364 | AC97 | HCT 116 | C108(0.58); C117(0.58); C400(0.66) | LDD0681 | [6] |
LDCM0365 | AC98 | HCT 116 | C507(0.36); C400(0.85) | LDD0682 | [6] |
LDCM0366 | AC99 | HCT 116 | C400(0.87); C507(1.06) | LDD0683 | [6] |
LDCM0520 | AKOS000195272 | MDA-MB-231 | C154(0.90) | LDD2113 | [4] |
LDCM0248 | AKOS034007472 | HCT 116 | C108(1.14); C117(1.14); C400(1.20); C507(1.08) | LDD0565 | [6] |
LDCM0356 | AKOS034007680 | HCT 116 | C400(1.03); C108(1.14); C117(1.14); C507(1.19) | LDD0673 | [6] |
LDCM0275 | AKOS034007705 | HCT 116 | C507(0.81); C400(0.85); C108(1.07); C117(1.07) | LDD0592 | [6] |
LDCM0156 | Aniline | NCI-H1299 | 12.36 | LDD0403 | [1] |
LDCM0020 | ARS-1620 | HCC44 | C154(0.92); C157(0.92) | LDD0078 | [6] |
LDCM0108 | Chloroacetamide | HeLa | C400(0.00); H22(0.00); C190(0.00); C154(0.00) | LDD0222 | [14] |
LDCM0632 | CL-Sc | Hep-G2 | C137(20.00); C507(0.45) | LDD2227 | [10] |
LDCM0367 | CL1 | HCT 116 | C507(0.94); C108(0.98); C117(0.98) | LDD0684 | [6] |
LDCM0368 | CL10 | HCT 116 | C507(0.47); C108(1.01); C117(1.01) | LDD0685 | [6] |
LDCM0369 | CL100 | HCT 116 | C400(0.97); C108(1.11); C117(1.11); C507(1.32) | LDD0686 | [6] |
LDCM0370 | CL101 | HCT 116 | C507(0.87); C400(0.98); C108(1.17); C117(1.17) | LDD0687 | [6] |
LDCM0371 | CL102 | HCT 116 | C507(1.01); C400(1.04); C108(1.15); C117(1.15) | LDD0688 | [6] |
LDCM0372 | CL103 | HCT 116 | C400(1.05); C507(1.12); C108(1.25); C117(1.25) | LDD0689 | [6] |
LDCM0373 | CL104 | HCT 116 | C108(1.00); C117(1.00); C507(1.00); C400(1.06) | LDD0690 | [6] |
LDCM0374 | CL105 | HCT 116 | C507(0.78); C400(0.99); C108(1.01); C117(1.01) | LDD0691 | [6] |
LDCM0375 | CL106 | HCT 116 | C507(0.86); C400(0.87); C108(0.93); C117(0.93) | LDD0692 | [6] |
LDCM0376 | CL107 | HCT 116 | C108(0.90); C117(0.90); C507(0.97); C400(1.02) | LDD0693 | [6] |
LDCM0377 | CL108 | HCT 116 | C507(0.79); C108(0.84); C117(0.84); C400(0.94) | LDD0694 | [6] |
LDCM0378 | CL109 | HCT 116 | C507(0.81); C108(0.88); C117(0.88); C400(0.94) | LDD0695 | [6] |
LDCM0379 | CL11 | HCT 116 | C507(0.63); C108(0.85); C117(0.85) | LDD0696 | [6] |
LDCM0380 | CL110 | HCT 116 | C400(0.89); C507(0.89); C108(0.99); C117(0.99) | LDD0697 | [6] |
LDCM0381 | CL111 | HCT 116 | C108(0.88); C117(0.88); C507(0.93); C400(1.00) | LDD0698 | [6] |
LDCM0382 | CL112 | HCT 116 | C400(0.85); C108(0.87); C117(0.87) | LDD0699 | [6] |
LDCM0383 | CL113 | HCT 116 | C400(0.70); C108(0.88); C117(0.88) | LDD0700 | [6] |
LDCM0384 | CL114 | HCT 116 | C400(0.71); C108(0.72); C117(0.72) | LDD0701 | [6] |
LDCM0385 | CL115 | HCT 116 | C400(0.76); C108(0.89); C117(0.89) | LDD0702 | [6] |
LDCM0386 | CL116 | HCT 116 | C400(0.78); C108(0.94); C117(0.94) | LDD0703 | [6] |
LDCM0387 | CL117 | HCT 116 | C400(0.83); C108(0.85); C117(0.85) | LDD0704 | [6] |
LDCM0388 | CL118 | HCT 116 | C108(0.99); C117(0.99); C400(1.02) | LDD0705 | [6] |
LDCM0389 | CL119 | HCT 116 | C108(0.96); C117(0.96); C400(0.97) | LDD0706 | [6] |
LDCM0390 | CL12 | HCT 116 | C507(0.50); C108(0.91); C117(0.91) | LDD0707 | [6] |
LDCM0391 | CL120 | HCT 116 | C108(0.99); C117(0.99); C400(1.06) | LDD0708 | [6] |
LDCM0392 | CL121 | HCT 116 | C507(0.81); C400(0.84); C108(1.85); C117(1.85) | LDD0709 | [6] |
LDCM0393 | CL122 | HCT 116 | C507(0.79); C400(0.89); C108(1.18); C117(1.18) | LDD0710 | [6] |
LDCM0394 | CL123 | HCT 116 | C507(0.83); C400(0.97); C108(1.15); C117(1.15) | LDD0711 | [6] |
LDCM0395 | CL124 | HCT 116 | C507(0.73); C400(0.80); C108(1.09); C117(1.09) | LDD0712 | [6] |
LDCM0396 | CL125 | HCT 116 | C400(0.99); C507(1.09); C108(1.16); C117(1.16) | LDD0713 | [6] |
LDCM0397 | CL126 | HCT 116 | C400(0.97); C507(1.00); C108(1.23); C117(1.23) | LDD0714 | [6] |
LDCM0398 | CL127 | HCT 116 | C400(0.84); C507(0.95); C108(1.13); C117(1.13) | LDD0715 | [6] |
LDCM0399 | CL128 | HCT 116 | C400(1.08); C108(1.08); C117(1.08); C507(1.12) | LDD0716 | [6] |
LDCM0400 | CL13 | HCT 116 | C507(0.70); C108(0.90); C117(0.90) | LDD0717 | [6] |
LDCM0401 | CL14 | HCT 116 | C507(0.87); C108(0.99); C117(0.99) | LDD0718 | [6] |
LDCM0402 | CL15 | HCT 116 | C507(0.97); C108(1.15); C117(1.15) | LDD0719 | [6] |
LDCM0403 | CL16 | HCT 116 | C400(0.99); C108(1.06); C117(1.06) | LDD0720 | [6] |
LDCM0404 | CL17 | HCT 116 | C108(1.04); C117(1.04); C400(1.22) | LDD0721 | [6] |
LDCM0405 | CL18 | HCT 116 | C400(1.00); C108(1.20); C117(1.20) | LDD0722 | [6] |
LDCM0406 | CL19 | HCT 116 | C400(0.95); C108(1.09); C117(1.09) | LDD0723 | [6] |
LDCM0407 | CL2 | HCT 116 | C108(0.90); C117(0.90); C507(0.97) | LDD0724 | [6] |
LDCM0408 | CL20 | HCT 116 | C400(0.96); C108(0.99); C117(0.99) | LDD0725 | [6] |
LDCM0409 | CL21 | HCT 116 | C400(0.96); C108(1.11); C117(1.11) | LDD0726 | [6] |
LDCM0410 | CL22 | HCT 116 | C400(0.66); C108(1.02); C117(1.02) | LDD0727 | [6] |
LDCM0411 | CL23 | HCT 116 | C400(0.89); C108(1.06); C117(1.06) | LDD0728 | [6] |
LDCM0412 | CL24 | HCT 116 | C400(0.97); C108(1.04); C117(1.04) | LDD0729 | [6] |
LDCM0413 | CL25 | HCT 116 | C108(1.25); C117(1.25); C400(1.04) | LDD0730 | [6] |
LDCM0414 | CL26 | HCT 116 | C108(0.87); C117(0.87); C400(1.03) | LDD0731 | [6] |
LDCM0415 | CL27 | HCT 116 | C108(1.33); C117(1.33); C400(1.00) | LDD0732 | [6] |
LDCM0416 | CL28 | HCT 116 | C108(1.05); C117(1.05); C400(1.10) | LDD0733 | [6] |
LDCM0417 | CL29 | HCT 116 | C108(1.26); C117(1.26); C400(0.88) | LDD0734 | [6] |
LDCM0418 | CL3 | HCT 116 | C108(0.92); C117(0.92); C507(0.93) | LDD0735 | [6] |
LDCM0419 | CL30 | HCT 116 | C108(1.02); C117(1.02); C400(1.03) | LDD0736 | [6] |
LDCM0420 | CL31 | HCT 116 | C400(1.11) | LDD0737 | [6] |
LDCM0421 | CL32 | HCT 116 | C400(1.14) | LDD0738 | [6] |
LDCM0422 | CL33 | HCT 116 | C400(1.05) | LDD0739 | [6] |
LDCM0423 | CL34 | HCT 116 | C400(0.90) | LDD0740 | [6] |
LDCM0424 | CL35 | HCT 116 | C400(0.92) | LDD0741 | [6] |
LDCM0425 | CL36 | HCT 116 | C400(0.92) | LDD0742 | [6] |
LDCM0426 | CL37 | HCT 116 | C400(0.92) | LDD0743 | [6] |
LDCM0428 | CL39 | HCT 116 | C400(0.96) | LDD0745 | [6] |
LDCM0429 | CL4 | HCT 116 | C108(0.94); C117(0.94); C507(0.82) | LDD0746 | [6] |
LDCM0430 | CL40 | HCT 116 | C400(1.01) | LDD0747 | [6] |
LDCM0431 | CL41 | HCT 116 | C400(0.98) | LDD0748 | [6] |
LDCM0432 | CL42 | HCT 116 | C400(1.07) | LDD0749 | [6] |
LDCM0433 | CL43 | HCT 116 | C400(1.06) | LDD0750 | [6] |
LDCM0434 | CL44 | HCT 116 | C400(1.02) | LDD0751 | [6] |
LDCM0435 | CL45 | HCT 116 | C400(1.01) | LDD0752 | [6] |
LDCM0436 | CL46 | HCT 116 | C108(1.01); C117(1.01); C400(1.22) | LDD0753 | [6] |
LDCM0437 | CL47 | HCT 116 | C108(1.02); C117(1.02); C400(1.25) | LDD0754 | [6] |
LDCM0438 | CL48 | HCT 116 | C108(1.01); C117(1.01); C400(1.23) | LDD0755 | [6] |
LDCM0439 | CL49 | HCT 116 | C108(0.94); C117(0.94); C400(1.11) | LDD0756 | [6] |
LDCM0440 | CL5 | HCT 116 | C108(0.99); C117(0.99); C507(0.80) | LDD0757 | [6] |
LDCM0441 | CL50 | HCT 116 | C108(1.02); C117(1.02); C400(1.31) | LDD0758 | [6] |
LDCM0442 | CL51 | HCT 116 | C108(1.07); C117(1.07); C400(1.21) | LDD0759 | [6] |
LDCM0443 | CL52 | HCT 116 | C108(0.99); C117(0.99); C400(1.17) | LDD0760 | [6] |
LDCM0444 | CL53 | HCT 116 | C108(0.95); C117(0.95); C400(1.10) | LDD0761 | [6] |
LDCM0445 | CL54 | HCT 116 | C108(1.09); C117(1.09); C400(1.16) | LDD0762 | [6] |
LDCM0446 | CL55 | HCT 116 | C108(0.97); C117(0.97); C400(1.21) | LDD0763 | [6] |
LDCM0447 | CL56 | HCT 116 | C108(1.02); C117(1.02); C400(1.16) | LDD0764 | [6] |
LDCM0448 | CL57 | HCT 116 | C108(1.14); C117(1.14); C400(1.17) | LDD0765 | [6] |
LDCM0449 | CL58 | HCT 116 | C108(1.05); C117(1.05); C400(1.19) | LDD0766 | [6] |
LDCM0450 | CL59 | HCT 116 | C108(1.01); C117(1.01); C400(1.18) | LDD0767 | [6] |
LDCM0451 | CL6 | HCT 116 | C108(0.90); C117(0.90); C507(0.79) | LDD0768 | [6] |
LDCM0452 | CL60 | HCT 116 | C108(0.95); C117(0.95); C400(1.14) | LDD0769 | [6] |
LDCM0453 | CL61 | HCT 116 | C108(1.03); C117(1.03); C400(1.11) | LDD0770 | [6] |
LDCM0454 | CL62 | HCT 116 | C108(0.87); C117(0.87); C400(1.04) | LDD0771 | [6] |
LDCM0455 | CL63 | HCT 116 | C108(0.95); C117(0.95); C400(0.91) | LDD0772 | [6] |
LDCM0456 | CL64 | HCT 116 | C108(0.96); C117(0.96); C400(0.99) | LDD0773 | [6] |
LDCM0457 | CL65 | HCT 116 | C108(0.92); C117(0.92); C400(1.01) | LDD0774 | [6] |
LDCM0458 | CL66 | HCT 116 | C108(1.03); C117(1.03); C400(1.01) | LDD0775 | [6] |
LDCM0459 | CL67 | HCT 116 | C108(0.83); C117(0.83); C400(0.82) | LDD0776 | [6] |
LDCM0460 | CL68 | HCT 116 | C108(0.97); C117(0.97); C400(0.89) | LDD0777 | [6] |
LDCM0461 | CL69 | HCT 116 | C108(1.01); C117(1.01); C400(0.95) | LDD0778 | [6] |
LDCM0462 | CL7 | HCT 116 | C108(0.85); C117(0.85); C507(0.56) | LDD0779 | [6] |
LDCM0463 | CL70 | HCT 116 | C108(0.98); C117(0.98); C400(0.95) | LDD0780 | [6] |
LDCM0464 | CL71 | HCT 116 | C108(0.90); C117(0.90); C400(1.12) | LDD0781 | [6] |
LDCM0465 | CL72 | HCT 116 | C108(0.83); C117(0.83); C400(0.87) | LDD0782 | [6] |
LDCM0466 | CL73 | HCT 116 | C108(0.85); C117(0.85); C400(0.90) | LDD0783 | [6] |
LDCM0467 | CL74 | HCT 116 | C108(0.96); C117(0.96); C400(0.92) | LDD0784 | [6] |
LDCM0469 | CL76 | HCT 116 | C400(0.90) | LDD0786 | [6] |
LDCM0470 | CL77 | HCT 116 | C400(0.90) | LDD0787 | [6] |
LDCM0471 | CL78 | HCT 116 | C400(0.93) | LDD0788 | [6] |
LDCM0472 | CL79 | HCT 116 | C400(0.84) | LDD0789 | [6] |
LDCM0473 | CL8 | HCT 116 | C108(0.87); C117(0.87); C507(0.70) | LDD0790 | [6] |
LDCM0474 | CL80 | HCT 116 | C400(0.88) | LDD0791 | [6] |
LDCM0475 | CL81 | HCT 116 | C400(0.94) | LDD0792 | [6] |
LDCM0476 | CL82 | HCT 116 | C400(0.81) | LDD0793 | [6] |
LDCM0477 | CL83 | HCT 116 | C400(0.84) | LDD0794 | [6] |
LDCM0478 | CL84 | HCT 116 | C400(0.77) | LDD0795 | [6] |
LDCM0479 | CL85 | HCT 116 | C400(1.00) | LDD0796 | [6] |
LDCM0480 | CL86 | HCT 116 | C400(0.95) | LDD0797 | [6] |
LDCM0481 | CL87 | HCT 116 | C400(0.90) | LDD0798 | [6] |
LDCM0482 | CL88 | HCT 116 | C400(0.79) | LDD0799 | [6] |
LDCM0483 | CL89 | HCT 116 | C400(0.73) | LDD0800 | [6] |
LDCM0484 | CL9 | HCT 116 | C108(0.98); C117(0.98); C507(0.79) | LDD0801 | [6] |
LDCM0485 | CL90 | HCT 116 | C400(0.77) | LDD0802 | [6] |
LDCM0486 | CL91 | HCT 116 | C108(0.78); C117(0.78); C400(1.07); C507(0.72) | LDD0803 | [6] |
LDCM0487 | CL92 | HCT 116 | C108(0.86); C117(0.86); C400(1.16); C507(1.00) | LDD0804 | [6] |
LDCM0488 | CL93 | HCT 116 | C108(0.89); C117(0.89); C400(1.34); C507(1.37) | LDD0805 | [6] |
LDCM0489 | CL94 | HCT 116 | C108(1.06); C117(1.06); C400(0.92); C507(1.65) | LDD0806 | [6] |
LDCM0490 | CL95 | HCT 116 | C108(0.81); C117(0.81); C400(1.27); C507(0.87) | LDD0807 | [6] |
LDCM0491 | CL96 | HCT 116 | C108(0.98); C117(0.98); C400(1.20); C507(0.83) | LDD0808 | [6] |
LDCM0492 | CL97 | HCT 116 | C108(1.19); C117(1.19); C400(0.97); C507(0.83) | LDD0809 | [6] |
LDCM0493 | CL98 | HCT 116 | C108(0.95); C117(0.95); C400(0.97); C507(1.10) | LDD0810 | [6] |
LDCM0494 | CL99 | HCT 116 | C108(0.90); C117(0.90); C400(1.01); C507(1.23) | LDD0811 | [6] |
LDCM0495 | E2913 | HEK-293T | C137(0.98); C51(0.94); C595(1.15); C78(0.92) | LDD1698 | [19] |
LDCM0625 | F8 | Ramos | C507(0.88); C51(0.40) | LDD2187 | [20] |
LDCM0572 | Fragment10 | Ramos | C400(0.96); C58(0.43); C507(0.35); C51(0.41) | LDD2189 | [20] |
LDCM0573 | Fragment11 | Ramos | C400(5.78); C58(1.87); C51(12.25); C414(0.42) | LDD2190 | [20] |
LDCM0574 | Fragment12 | Ramos | C58(0.43); C507(0.66); C51(0.57); C414(0.72) | LDD2191 | [20] |
LDCM0575 | Fragment13 | Ramos | C400(0.97); C58(0.64); C507(0.34); C414(0.71) | LDD2192 | [20] |
LDCM0576 | Fragment14 | Ramos | C400(1.60); C58(0.83); C507(0.45); C414(1.06) | LDD2193 | [20] |
LDCM0579 | Fragment20 | Ramos | C507(0.80); C51(1.54); C414(0.82) | LDD2194 | [20] |
LDCM0580 | Fragment21 | Ramos | C400(0.97); C58(0.31); C507(0.58); C51(0.76) | LDD2195 | [20] |
LDCM0582 | Fragment23 | Ramos | C400(0.62); C58(0.57); C507(0.60); C51(1.17) | LDD2196 | [20] |
LDCM0578 | Fragment27 | Ramos | C400(0.95); C58(0.74); C507(0.55); C51(0.70) | LDD2197 | [20] |
LDCM0586 | Fragment28 | Ramos | C400(0.62); C58(0.60); C507(0.40); C51(0.90) | LDD2198 | [20] |
LDCM0588 | Fragment30 | Ramos | C400(0.80); C58(0.32); C507(0.41); C414(0.62) | LDD2199 | [20] |
LDCM0589 | Fragment31 | Ramos | C400(0.91); C58(0.78); C507(0.52); C51(0.52) | LDD2200 | [20] |
LDCM0590 | Fragment32 | Ramos | C58(0.74); C507(0.41); C51(1.14); C414(0.50) | LDD2201 | [20] |
LDCM0468 | Fragment33 | HCT 116 | C108(0.89); C117(0.89); C400(1.00) | LDD0785 | [6] |
LDCM0596 | Fragment38 | Ramos | C400(0.91); C58(0.47); C507(0.63); C51(1.59) | LDD2203 | [20] |
LDCM0566 | Fragment4 | Ramos | C400(0.93); C507(0.87); C414(0.64) | LDD2184 | [20] |
LDCM0427 | Fragment51 | HCT 116 | C400(0.54) | LDD0744 | [6] |
LDCM0610 | Fragment52 | Ramos | C400(1.01); C507(0.48) | LDD2204 | [20] |
LDCM0614 | Fragment56 | Ramos | C400(1.24); C507(0.46); C51(0.94); C414(0.67) | LDD2205 | [20] |
LDCM0569 | Fragment7 | Ramos | C58(0.79); C507(1.11); C51(0.41); C414(1.07) | LDD2186 | [20] |
LDCM0571 | Fragment9 | Ramos | C507(0.54); C51(1.28); C414(0.74) | LDD2188 | [20] |
LDCM0107 | IAA | HeLa | C190(0.00); C154(0.00) | LDD0221 | [14] |
LDCM0022 | KB02 | HCT 116 | C108(1.64); C117(1.64); C154(1.74); C157(1.74) | LDD0080 | [6] |
LDCM0023 | KB03 | HCT 116 | C108(1.74); C117(1.74); C154(2.35); C157(2.35) | LDD0081 | [6] |
LDCM0024 | KB05 | HCT 116 | C108(1.74); C117(1.74); C154(1.69); C157(1.69) | LDD0082 | [6] |
LDCM0109 | NEM | HeLa | N.A. | LDD0223 | [14] |
LDCM0501 | Nucleophilic fragment 13b | MDA-MB-231 | C137(1.24) | LDD2094 | [4] |
LDCM0504 | Nucleophilic fragment 15a | MDA-MB-231 | C154(0.98) | LDD2097 | [4] |
LDCM0516 | Nucleophilic fragment 21a | MDA-MB-231 | C400(0.88) | LDD2109 | [4] |
LDCM0522 | Nucleophilic fragment 24a | MDA-MB-231 | C154(0.70) | LDD2115 | [4] |
LDCM0527 | Nucleophilic fragment 26b | MDA-MB-231 | C154(0.84) | LDD2120 | [4] |
LDCM0530 | Nucleophilic fragment 28a | MDA-MB-231 | C400(0.96); C154(0.95) | LDD2123 | [4] |
LDCM0534 | Nucleophilic fragment 30a | MDA-MB-231 | C190(0.87) | LDD2127 | [4] |
LDCM0535 | Nucleophilic fragment 30b | MDA-MB-231 | C154(0.71) | LDD2128 | [4] |
LDCM0536 | Nucleophilic fragment 31 | MDA-MB-231 | C400(1.23); C190(1.01) | LDD2129 | [4] |
LDCM0541 | Nucleophilic fragment 36 | MDA-MB-231 | C154(0.49) | LDD2134 | [4] |
LDCM0543 | Nucleophilic fragment 38 | MDA-MB-231 | C154(0.87) | LDD2136 | [4] |
LDCM0544 | Nucleophilic fragment 39 | MDA-MB-231 | C154(0.92) | LDD2137 | [4] |
LDCM0549 | Nucleophilic fragment 43 | MDA-MB-231 | C154(0.69) | LDD2143 | [4] |
The Interaction Atlas With This Target
The Protein(s) Related To This Target
Enzyme
Transcription factor
Protein name | Family | Uniprot ID | |||
---|---|---|---|---|---|
ETS-related transcription factor Elf-3 (ELF3) | ETS family | P78545 | |||
Nucleus accumbens-associated protein 1 (NACC1) | . | Q96RE7 | |||
Transcription factor SOX-2 (SOX2) | . | P48431 |
Other
The Drug(s) Related To This Target
Approved
Drug Name | Drug Type | External ID | |||
---|---|---|---|---|---|
Dequalinium | Small molecular drug | DB04209 | |||
Fostamatinib | Small molecular drug | DB12010 | |||
Tamoxifen | Small molecular drug | DB00675 | |||
Benzoyl Peroxide | . | DB09096 |
Investigative
Drug Name | Drug Type | External ID | |||
---|---|---|---|---|---|
Bisindolylmaleimide I | Small molecular drug | DB03777 | |||
Staurosporine | Small molecular drug | DB02010 | |||
Crt-0004592 | . | D0K6ES |
Discontinued
Drug Name | Drug Type | External ID | |||
---|---|---|---|---|---|
Ica-1 | . | D0B8NW |
References