Details of the Target

General Information of Target

Target ID LDTP19497
Target Name Armadillo repeat-containing X-linked protein 5 (ARMCX5)
Gene Name ARMCX5
Gene ID 64860
Synonyms
Armadillo repeat-containing X-linked protein 5
3D Structure
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2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MAATLQFLVCLVVAICLLSGVTTTQPHAGQPMDSTSVGGGLQEPEAPEVMFELLWAGLEL
DVMGQLHIQDEELASTHPGRRLRLLLQHHVPSDLEGTEQWLQQLQDLRKGPPLSTWDFEH
LLLTGLSCVYRLHAASEAEERGRWAQVFALLAQETLWDLCKGFCPQDRPPSLGSWASILD
PFP
Target Bioclass
Other
Family
Eutherian X-chromosome-specific Armcx family
Uniprot ID
Q6P1M9
Ensemble ID
ENST00000246174.6
HGNC ID
HGNC:25772

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C458(1.12)  LDD0531  [1]
PF-06672131
 Probe Info  		N.A.  LDD0152  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C458(1.12)  LDD0531  [1]
 LDCM0216  AC100 HEK-293T C458(0.90)  LDD0814  [1]
 LDCM0217  AC101 HEK-293T C458(0.96)  LDD0815  [1]
 LDCM0218  AC102 HEK-293T C458(1.08)  LDD0816  [1]
 LDCM0219  AC103 HEK-293T C458(0.97)  LDD0817  [1]
 LDCM0220  AC104 HEK-293T C458(1.10)  LDD0818  [1]
 LDCM0221  AC105 HEK-293T C458(0.88)  LDD0819  [1]
 LDCM0222  AC106 HEK-293T C458(1.21)  LDD0820  [1]
 LDCM0223  AC107 HEK-293T C458(0.78)  LDD0821  [1]
 LDCM0224  AC108 HEK-293T C458(1.22)  LDD0822  [1]
 LDCM0225  AC109 HEK-293T C458(0.91)  LDD0823  [1]
 LDCM0226  AC11 HEK-293T C403(1.04)  LDD1509  [3]
 LDCM0227  AC110 HEK-293T C458(0.79)  LDD0825  [1]
 LDCM0228  AC111 HEK-293T C458(0.69)  LDD0826  [1]
 LDCM0229  AC112 HEK-293T C458(0.89)  LDD0827  [1]
 LDCM0230  AC113 HEK-293T C458(1.60)  LDD0828  [1]
 LDCM0231  AC114 HEK-293T C458(0.99)  LDD0829  [1]
 LDCM0232  AC115 HEK-293T C458(1.13)  LDD0830  [1]
 LDCM0233  AC116 HEK-293T C458(1.41)  LDD0831  [1]
 LDCM0234  AC117 HEK-293T C458(1.15)  LDD0832  [1]
 LDCM0235  AC118 HEK-293T C458(1.07)  LDD0833  [1]
 LDCM0236  AC119 HEK-293T C458(1.50)  LDD0834  [1]
 LDCM0237  AC12 HEK-293T C403(0.91)  LDD1510  [3]
 LDCM0238  AC120 HEK-293T C458(2.02)  LDD0836  [1]
 LDCM0239  AC121 HEK-293T C458(1.45)  LDD0837  [1]
 LDCM0240  AC122 HEK-293T C458(1.34)  LDD0838  [1]
 LDCM0241  AC123 HEK-293T C458(1.24)  LDD0839  [1]
 LDCM0242  AC124 HEK-293T C458(1.41)  LDD0840  [1]
 LDCM0243  AC125 HEK-293T C458(1.17)  LDD0841  [1]
 LDCM0244  AC126 HEK-293T C458(1.44)  LDD0842  [1]
 LDCM0245  AC127 HEK-293T C458(1.31)  LDD0843  [1]
 LDCM0246  AC128 HEK-293T C458(1.03)  LDD0844  [1]
 LDCM0247  AC129 HEK-293T C458(0.92)  LDD0845  [1]
 LDCM0249  AC130 HEK-293T C458(1.50)  LDD0847  [1]
 LDCM0250  AC131 HEK-293T C458(1.30)  LDD0848  [1]
 LDCM0251  AC132 HEK-293T C458(1.05)  LDD0849  [1]
 LDCM0252  AC133 HEK-293T C458(0.99)  LDD0850  [1]
 LDCM0253  AC134 HEK-293T C458(0.99)  LDD0851  [1]
 LDCM0254  AC135 HEK-293T C458(1.54)  LDD0852  [1]
 LDCM0255  AC136 HEK-293T C458(1.19)  LDD0853  [1]
 LDCM0256  AC137 HEK-293T C458(1.00)  LDD0854  [1]
 LDCM0257  AC138 HEK-293T C458(1.02)  LDD0855  [1]
 LDCM0258  AC139 HEK-293T C458(1.29)  LDD0856  [1]
 LDCM0259  AC14 HEK-293T C403(0.99)  LDD1512  [3]
 LDCM0260  AC140 HEK-293T C458(1.22)  LDD0858  [1]
 LDCM0261  AC141 HEK-293T C458(1.15)  LDD0859  [1]
 LDCM0262  AC142 HEK-293T C458(1.35)  LDD0860  [1]
 LDCM0270  AC15 HEK-293T C403(0.98)  LDD1513  [3]
 LDCM0276  AC17 HCT 116 C458(1.47)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C458(1.62)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C458(1.18)  LDD0595  [1]
 LDCM0279  AC2 HCT 116 C458(1.08)  LDD0596  [1]
 LDCM0280  AC20 HCT 116 C458(0.90)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C458(1.77)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C458(1.14)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C458(1.35)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C458(1.19)  LDD0601  [1]
 LDCM0285  AC25 HCT 116 C458(1.01)  LDD0602  [1]
 LDCM0286  AC26 HCT 116 C458(1.28)  LDD0603  [1]
 LDCM0287  AC27 HCT 116 C458(1.10)  LDD0604  [1]
 LDCM0288  AC28 HCT 116 C458(1.22)  LDD0605  [1]
 LDCM0289  AC29 HCT 116 C458(1.48)  LDD0606  [1]
 LDCM0290  AC3 HCT 116 C458(1.00)  LDD0607  [1]
 LDCM0291  AC30 HCT 116 C458(1.25)  LDD0608  [1]
 LDCM0292  AC31 HCT 116 C458(1.26)  LDD0609  [1]
 LDCM0293  AC32 HCT 116 C458(1.22)  LDD0610  [1]
 LDCM0294  AC33 HCT 116 C458(1.05)  LDD0611  [1]
 LDCM0295  AC34 HCT 116 C458(0.80)  LDD0612  [1]
 LDCM0296  AC35 HEK-293T C403(0.90)  LDD1535  [3]
 LDCM0297  AC36 HEK-293T C403(0.99)  LDD1536  [3]
 LDCM0299  AC38 HEK-293T C403(0.98)  LDD1538  [3]
 LDCM0300  AC39 HEK-293T C403(1.08)  LDD1539  [3]
 LDCM0301  AC4 HCT 116 C458(1.16)  LDD0618  [1]
 LDCM0303  AC41 HEK-293T C403(1.01)  LDD1542  [3]
 LDCM0305  AC43 HEK-293T C403(0.99)  LDD1544  [3]
 LDCM0306  AC44 HEK-293T C403(0.98)  LDD1545  [3]
 LDCM0308  AC46 HEK-293T C403(0.96)  LDD1547  [3]
 LDCM0309  AC47 HEK-293T C403(0.99)  LDD1548  [3]
 LDCM0311  AC49 HEK-293T C403(0.89)  LDD1550  [3]
 LDCM0312  AC5 HCT 116 C458(1.11)  LDD0629  [1]
 LDCM0314  AC51 HEK-293T C403(0.97)  LDD1553  [3]
 LDCM0315  AC52 HEK-293T C403(0.85)  LDD1554  [3]
 LDCM0317  AC54 HEK-293T C403(0.93)  LDD1556  [3]
 LDCM0318  AC55 HEK-293T C403(0.91)  LDD1557  [3]
 LDCM0320  AC57 HEK-293T C458(0.99)  LDD0918  [1]
 LDCM0321  AC58 HEK-293T C458(0.90)  LDD0919  [1]
 LDCM0322  AC59 HEK-293T C458(1.05)  LDD0920  [1]
 LDCM0323  AC6 HEK-293T C403(0.95)  LDD1562  [3]
 LDCM0324  AC60 HEK-293T C458(3.76)  LDD0922  [1]
 LDCM0325  AC61 HEK-293T C458(0.97)  LDD0923  [1]
 LDCM0326  AC62 HEK-293T C458(0.95)  LDD0924  [1]
 LDCM0327  AC63 HEK-293T C458(1.07)  LDD0925  [1]
 LDCM0328  AC64 HEK-293T C458(0.92)  LDD0926  [1]
 LDCM0329  AC65 HEK-293T C458(0.86)  LDD0927  [1]
 LDCM0330  AC66 HEK-293T C458(0.87)  LDD0928  [1]
 LDCM0331  AC67 HEK-293T C458(0.76)  LDD0929  [1]
 LDCM0334  AC7 HEK-293T C403(1.00)  LDD1568  [3]
 LDCM0349  AC83 HEK-293T C458(0.84)  LDD0947  [1]
 LDCM0350  AC84 HEK-293T C458(1.19)  LDD0948  [1]
 LDCM0351  AC85 HEK-293T C458(0.94)  LDD0949  [1]
 LDCM0352  AC86 HEK-293T C458(0.88)  LDD0950  [1]
 LDCM0353  AC87 HEK-293T C458(1.45)  LDD0951  [1]
 LDCM0354  AC88 HEK-293T C458(1.18)  LDD0952  [1]
 LDCM0355  AC89 HEK-293T C458(1.35)  LDD0953  [1]
 LDCM0357  AC90 HEK-293T C458(1.13)  LDD0955  [1]
 LDCM0358  AC91 HEK-293T C458(1.31)  LDD0956  [1]
 LDCM0359  AC92 HEK-293T C458(0.89)  LDD0957  [1]
 LDCM0360  AC93 HEK-293T C458(0.92)  LDD0958  [1]
 LDCM0361  AC94 HEK-293T C458(1.50)  LDD0959  [1]
 LDCM0362  AC95 HEK-293T C458(1.18)  LDD0960  [1]
 LDCM0363  AC96 HEK-293T C458(1.17)  LDD0961  [1]
 LDCM0364  AC97 HEK-293T C458(0.97)  LDD0962  [1]
 LDCM0365  AC98 HEK-293T C458(0.98)  LDD0963  [1]
 LDCM0366  AC99 HEK-293T C458(1.09)  LDD0964  [1]
 LDCM0356  AKOS034007680 HEK-293T C403(0.91)  LDD1570  [3]
 LDCM0368  CL10 HEK-293T C403(1.54)  LDD1572  [3]
 LDCM0369  CL100 HCT 116 C458(0.91)  LDD0686  [1]
 LDCM0371  CL102 HEK-293T C403(1.14)  LDD1575  [3]
 LDCM0372  CL103 HEK-293T C403(1.13)  LDD1576  [3]
 LDCM0373  CL104 HEK-293T C403(0.87)  LDD1577  [3]
 LDCM0374  CL105 HCT 116 C458(1.47)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C458(1.38)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C458(1.29)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C458(1.28)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C458(1.30)  LDD0695  [1]
 LDCM0379  CL11 HEK-293T C403(1.39)  LDD1583  [3]
 LDCM0380  CL110 HCT 116 C458(1.25)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C458(1.23)  LDD0698  [1]
 LDCM0382  CL112 HCT 116 C458(0.97)  LDD0699  [1]
 LDCM0383  CL113 HCT 116 C458(0.95)  LDD0700  [1]
 LDCM0384  CL114 HCT 116 C458(1.09)  LDD0701  [1]
 LDCM0385  CL115 HCT 116 C458(1.08)  LDD0702  [1]
 LDCM0386  CL116 HCT 116 C458(1.00)  LDD0703  [1]
 LDCM0388  CL118 HEK-293T C403(0.97)  LDD1592  [3]
 LDCM0389  CL119 HEK-293T C403(0.99)  LDD1593  [3]
 LDCM0391  CL120 HEK-293T C403(0.83)  LDD1595  [3]
 LDCM0393  CL122 HEK-293T C403(0.97)  LDD1597  [3]
 LDCM0394  CL123 HEK-293T C403(1.15)  LDD1598  [3]
 LDCM0395  CL124 HEK-293T C403(0.99)  LDD1599  [3]
 LDCM0396  CL125 HEK-293T C458(1.21)  LDD0994  [1]
 LDCM0397  CL126 HEK-293T C458(0.96)  LDD0995  [1]
 LDCM0398  CL127 HEK-293T C458(0.76)  LDD0996  [1]
 LDCM0399  CL128 HEK-293T C458(0.81)  LDD0997  [1]
 LDCM0401  CL14 HEK-293T C403(1.17)  LDD1605  [3]
 LDCM0402  CL15 HEK-293T C403(1.10)  LDD1606  [3]
 LDCM0403  CL16 HEK-293T C403(1.04)  LDD1607  [3]
 LDCM0404  CL17 HEK-293T C403(1.25)  LDD1608  [3]
 LDCM0406  CL19 HEK-293T C403(1.00)  LDD1610  [3]
 LDCM0407  CL2 HEK-293T C403(1.06)  LDD1611  [3]
 LDCM0408  CL20 HEK-293T C403(1.19)  LDD1612  [3]
 LDCM0410  CL22 HEK-293T C403(1.15)  LDD1614  [3]
 LDCM0411  CL23 HEK-293T C403(1.41)  LDD1615  [3]
 LDCM0414  CL26 HEK-293T C403(1.07)  LDD1618  [3]
 LDCM0415  CL27 HEK-293T C403(1.01)  LDD1619  [3]
 LDCM0416  CL28 HEK-293T C403(1.17)  LDD1620  [3]
 LDCM0417  CL29 HEK-293T C403(0.98)  LDD1621  [3]
 LDCM0418  CL3 HEK-293T C403(1.11)  LDD1622  [3]
 LDCM0420  CL31 HCT 116 C458(0.98)  LDD0737  [1]
 LDCM0421  CL32 HCT 116 C458(0.98)  LDD0738  [1]
 LDCM0422  CL33 HCT 116 C458(0.96)  LDD0739  [1]
 LDCM0423  CL34 HCT 116 C458(1.14)  LDD0740  [1]
 LDCM0424  CL35 HCT 116 C458(1.08)  LDD0741  [1]
 LDCM0425  CL36 HCT 116 C458(1.01)  LDD0742  [1]
 LDCM0426  CL37 HCT 116 C458(0.98)  LDD0743  [1]
 LDCM0428  CL39 HCT 116 C458(0.92)  LDD0745  [1]
 LDCM0429  CL4 HEK-293T C403(1.07)  LDD1633  [3]
 LDCM0430  CL40 HCT 116 C458(0.88)  LDD0747  [1]
 LDCM0431  CL41 HCT 116 C458(1.09)  LDD0748  [1]
 LDCM0432  CL42 HCT 116 C458(1.00)  LDD0749  [1]
 LDCM0433  CL43 HCT 116 C458(0.93)  LDD0750  [1]
 LDCM0434  CL44 HCT 116 C458(1.07)  LDD0751  [1]
 LDCM0435  CL45 HCT 116 C458(1.06)  LDD0752  [1]
 LDCM0436  CL46 HEK-293T C403(1.40)  LDD1640  [3]
 LDCM0437  CL47 HEK-293T C403(1.24)  LDD1641  [3]
 LDCM0440  CL5 HEK-293T C403(1.02)  LDD1644  [3]
 LDCM0441  CL50 HEK-293T C403(1.25)  LDD1645  [3]
 LDCM0443  CL52 HEK-293T C403(0.96)  LDD1646  [3]
 LDCM0444  CL53 HEK-293T C403(0.92)  LDD1647  [3]
 LDCM0446  CL55 HEK-293T C403(1.12)  LDD1649  [3]
 LDCM0447  CL56 HEK-293T C403(1.20)  LDD1650  [3]
 LDCM0449  CL58 HEK-293T C403(1.28)  LDD1652  [3]
 LDCM0450  CL59 HEK-293T C403(1.32)  LDD1653  [3]
 LDCM0454  CL62 HEK-293T C403(0.98)  LDD1657  [3]
 LDCM0455  CL63 HEK-293T C403(1.01)  LDD1658  [3]
 LDCM0456  CL64 HEK-293T C403(1.20)  LDD1659  [3]
 LDCM0457  CL65 HEK-293T C403(0.89)  LDD1660  [3]
 LDCM0459  CL67 HEK-293T C403(1.07)  LDD1662  [3]
 LDCM0460  CL68 HEK-293T C403(1.18)  LDD1663  [3]
 LDCM0462  CL7 HEK-293T C403(0.98)  LDD1665  [3]
 LDCM0463  CL70 HEK-293T C403(1.14)  LDD1666  [3]
 LDCM0464  CL71 HEK-293T C403(1.16)  LDD1667  [3]
 LDCM0467  CL74 HEK-293T C403(1.02)  LDD1670  [3]
 LDCM0469  CL76 HEK-293T C403(0.80)  LDD1672  [3]
 LDCM0470  CL77 HEK-293T C403(0.96)  LDD1673  [3]
 LDCM0472  CL79 HEK-293T C403(1.14)  LDD1675  [3]
 LDCM0473  CL8 HEK-293T C403(1.30)  LDD1676  [3]
 LDCM0474  CL80 HEK-293T C403(1.02)  LDD1677  [3]
 LDCM0476  CL82 HEK-293T C403(1.32)  LDD1679  [3]
 LDCM0477  CL83 HEK-293T C403(1.09)  LDD1680  [3]
 LDCM0480  CL86 HEK-293T C403(0.74)  LDD1683  [3]
 LDCM0481  CL87 HEK-293T C403(1.03)  LDD1684  [3]
 LDCM0482  CL88 HEK-293T C403(0.98)  LDD1685  [3]
 LDCM0483  CL89 HEK-293T C403(0.98)  LDD1686  [3]
 LDCM0486  CL91 HCT 116 C458(1.05)  LDD0803  [1]
 LDCM0487  CL92 HCT 116 C458(0.84)  LDD0804  [1]
 LDCM0488  CL93 HCT 116 C458(0.88)  LDD0805  [1]
 LDCM0489  CL94 HCT 116 C458(0.88)  LDD0806  [1]
 LDCM0490  CL95 HCT 116 C458(1.01)  LDD0807  [1]
 LDCM0491  CL96 HCT 116 C458(0.99)  LDD0808  [1]
 LDCM0492  CL97 HCT 116 C458(1.01)  LDD0809  [1]
 LDCM0493  CL98 HCT 116 C458(1.03)  LDD0810  [1]
 LDCM0494  CL99 HCT 116 C458(0.89)  LDD0811  [1]
 LDCM0495  E2913 HEK-293T C403(1.08)  LDD1698  [3]
 LDCM0468  Fragment33 HEK-293T C403(0.94)  LDD1671  [3]
 LDCM0427  Fragment51 HCT 116 C458(1.35)  LDD0744  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Huntingtin (HTT) Huntingtin family P42858
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Amyloid protein-binding protein 2 (APPBP2) . Q92624

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 Site-Specific Activity-Based Protein Profiling Using Phosphonate Handles. Mol Cell Proteomics. 2023 Jan;22(1):100455. doi: 10.1016/j.mcpro.2022.100455. Epub 2022 Nov 24.
Mass spectrometry data entry: PXD036569
3 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402