Details of the Target

General Information of Target

Target ID LDTP02230
Target Name Laminin subunit beta-1 (LAMB1)
Gene Name LAMB1
Gene ID 3912
Synonyms
Laminin subunit beta-1; Laminin B1 chain; Laminin-1 subunit beta; Laminin-10 subunit beta; Laminin-12 subunit beta; Laminin-2 subunit beta; Laminin-6 subunit beta; Laminin-8 subunit beta
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGLLQLLAFSFLALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHK
PEPYCIVSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVEN
VTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDCEASFPGISTG
PMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKL
HTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMC
RHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGG
VCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTG
LIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCY
CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQC
NEVEPGYYFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVPEGAYLEFF
IDNIPYSMEYDILIRYEPQLPDHWEKAVITVQRPGRIPTSSRCGNTIPDDDNQVVSLSPG
SRYVVLPRPVCFEKGTNYTVRLELPQYTSSDSDVESPYTLIDSLVLMPYCKSLDIFTVGG
SGDGVVTNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGS
LSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQC
HCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLA
GYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCAS
GYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDA
LQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTG
CDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIE
TPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRF
LEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAAEPLKNIGNLFEEAEKLIKDV
TEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDS
ITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDE
LAGKLQSLDLSAAAEMTCGTPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNA
WQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEEL
RNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVI
LQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDI
QGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVK
QSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLL
KDLERKYEDNQRYLEDKAQELARLEGEVRSLLKDISQKVAVYSTCL
Target Bioclass
Other
Subcellular location
Secreted, extracellular space, extracellular matrix, basement membrane
Function
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface.
Uniprot ID
P07942
Ensemble ID
ENST00000222399.11
HGNC ID
HGNC:6486
ChEMBL ID
CHEMBL2364187

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 14 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DA-P2
 Probe Info  		9.94  LDD0348  [1]
HRP
 Probe Info  		6.61  LDD0347  [1]
STPyne
 Probe Info  		K1736(7.69); K1741(2.10)  LDD0277  [2]
OPA-S-S-alkyne
 Probe Info  		K1778(1.02); K184(1.21); K1368(1.59); K1370(1.62)  LDD3494  [3]
BTD
 Probe Info  		C755(0.92); C671(1.26); C332(1.60)  LDD2099  [4]
DA-P3
 Probe Info  		5.61  LDD0179  [1]
HHS-475
 Probe Info  		Y663(0.61)  LDD0264  [5]
DBIA
 Probe Info  		C1425(3.84); C1430(3.84)  LDD0080  [6]
m-APA
 Probe Info  		H86(0.00); H1563(0.00)  LDD2231  [7]
IA-alkyne
 Probe Info  		C374(0.00); C755(0.00); C395(0.00); C1785(0.00)  LDD0162  [8]
PF-06672131
 Probe Info  		N.A.  LDD0017  [9]
Acrolein
 Probe Info  		C190(0.00); H1563(0.00)  LDD0217  [10]
HHS-465
 Probe Info  		N.A.  LDD2240  [11]
HHS-482
 Probe Info  		Y663(0.56)  LDD2239  [12]
PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C017
 Probe Info  		5.86  LDD1725  [13]
C310
 Probe Info  		9.06  LDD1977  [13]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C755(1.46); C332(1.61)  LDD2117  [4]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C755(1.19)  LDD2152  [4]
 LDCM0214  AC1 HCT 116 C1430(1.16); C1785(1.05); C309(1.14)  LDD0531  [6]
 LDCM0215  AC10 HCT 116 C1425(0.99); C1430(0.99)  LDD0532  [6]
 LDCM0216  AC100 HCT 116 C1425(0.89); C1430(0.89); C1785(0.84)  LDD0533  [6]
 LDCM0217  AC101 HCT 116 C1425(0.98); C1430(0.98); C1785(0.95)  LDD0534  [6]
 LDCM0218  AC102 HCT 116 C1425(0.95); C1430(0.95); C1785(0.97)  LDD0535  [6]
 LDCM0219  AC103 HCT 116 C1425(1.19); C1430(1.19); C1785(1.11)  LDD0536  [6]
 LDCM0220  AC104 HCT 116 C1425(1.07); C1430(1.07); C1785(1.16)  LDD0537  [6]
 LDCM0221  AC105 HCT 116 C1425(1.34); C1430(1.34); C1785(0.96)  LDD0538  [6]
 LDCM0222  AC106 HCT 116 C1425(0.99); C1430(0.99); C1785(0.90)  LDD0539  [6]
 LDCM0223  AC107 HCT 116 C1425(1.07); C1430(1.07); C1785(0.51)  LDD0540  [6]
 LDCM0224  AC108 HCT 116 C1425(0.87); C1430(0.87); C1785(1.48)  LDD0541  [6]
 LDCM0225  AC109 HCT 116 C1425(0.93); C1430(0.93); C1785(1.37)  LDD0542  [6]
 LDCM0226  AC11 HCT 116 C1425(1.05); C1430(1.05)  LDD0543  [6]
 LDCM0227  AC110 HCT 116 C1425(1.01); C1430(1.01); C1785(1.09)  LDD0544  [6]
 LDCM0228  AC111 HCT 116 C1425(1.04); C1430(1.04); C1785(1.29)  LDD0545  [6]
 LDCM0229  AC112 HCT 116 C1425(1.03); C1430(1.03); C1785(0.78)  LDD0546  [6]
 LDCM0230  AC113 HCT 116 C1425(1.08); C1430(0.94); C1785(1.04)  LDD0547  [6]
 LDCM0231  AC114 HCT 116 C1425(1.28); C1430(1.30); C1785(1.13)  LDD0548  [6]
 LDCM0232  AC115 HCT 116 C1425(1.38); C1430(1.28); C1785(0.97)  LDD0549  [6]
 LDCM0233  AC116 HCT 116 C1425(1.33); C1430(1.35); C1785(1.08)  LDD0550  [6]
 LDCM0234  AC117 HCT 116 C1425(1.15); C1430(1.18); C1785(1.13)  LDD0551  [6]
 LDCM0235  AC118 HCT 116 C1425(1.15); C1430(1.08); C1785(0.98)  LDD0552  [6]
 LDCM0236  AC119 HCT 116 C1425(1.09); C1430(1.18); C1785(1.23)  LDD0553  [6]
 LDCM0237  AC12 HCT 116 C1425(0.88); C1430(0.88)  LDD0554  [6]
 LDCM0238  AC120 HCT 116 C1425(1.15); C1430(1.06); C1785(0.94)  LDD0555  [6]
 LDCM0239  AC121 HCT 116 C1425(1.07); C1430(1.13); C1785(0.93)  LDD0556  [6]
 LDCM0240  AC122 HCT 116 C1425(1.08); C1430(1.05); C1785(0.98)  LDD0557  [6]
 LDCM0241  AC123 HCT 116 C1425(1.04); C1430(0.99); C1785(1.04)  LDD0558  [6]
 LDCM0242  AC124 HCT 116 C1425(1.22); C1430(1.41); C1785(0.84)  LDD0559  [6]
 LDCM0243  AC125 HCT 116 C1425(1.14); C1430(1.11); C1785(1.09)  LDD0560  [6]
 LDCM0244  AC126 HCT 116 C1425(1.29); C1430(1.23); C1785(1.07)  LDD0561  [6]
 LDCM0245  AC127 HCT 116 C1425(1.31); C1430(1.31); C1785(1.10)  LDD0562  [6]
 LDCM0246  AC128 HCT 116 C1425(0.91); C1430(0.91); C309(0.49)  LDD0563  [6]
 LDCM0247  AC129 HCT 116 C1425(0.62); C1430(0.62); C309(0.91)  LDD0564  [6]
 LDCM0249  AC130 HCT 116 C1425(0.67); C1430(0.67); C309(1.12)  LDD0566  [6]
 LDCM0250  AC131 HCT 116 C1425(0.98); C1430(0.98); C309(0.70)  LDD0567  [6]
 LDCM0251  AC132 HCT 116 C1425(0.77); C1430(0.77); C309(1.13)  LDD0568  [6]
 LDCM0252  AC133 HCT 116 C1425(0.73); C1430(0.73); C309(0.81)  LDD0569  [6]
 LDCM0253  AC134 HCT 116 C1425(0.92); C1430(0.92); C309(0.99)  LDD0570  [6]
 LDCM0254  AC135 HCT 116 C1425(0.86); C1430(0.86); C309(1.08)  LDD0571  [6]
 LDCM0255  AC136 HCT 116 C1425(1.03); C1430(1.03); C309(1.17)  LDD0572  [6]
 LDCM0256  AC137 HCT 116 C1425(0.91); C1430(0.91); C309(0.80)  LDD0573  [6]
 LDCM0257  AC138 HCT 116 C1425(0.97); C1430(0.97); C309(1.79)  LDD0574  [6]
 LDCM0258  AC139 HCT 116 C1425(0.88); C1430(0.88); C309(1.28)  LDD0575  [6]
 LDCM0259  AC14 HCT 116 C1425(0.97); C1430(0.97)  LDD0576  [6]
 LDCM0260  AC140 HCT 116 C1425(0.97); C1430(0.97); C309(1.90)  LDD0577  [6]
 LDCM0261  AC141 HCT 116 C1425(1.02); C1430(1.02); C309(1.48)  LDD0578  [6]
 LDCM0262  AC142 HCT 116 C1425(0.83); C1430(0.83); C309(1.78)  LDD0579  [6]
 LDCM0263  AC143 HCT 116 C1425(0.95); C1430(0.95)  LDD0580  [6]
 LDCM0264  AC144 HCT 116 C1425(1.33); C1430(1.33)  LDD0581  [6]
 LDCM0265  AC145 HCT 116 C1425(1.15); C1430(1.15)  LDD0582  [6]
 LDCM0266  AC146 HCT 116 C1425(1.08); C1430(1.08)  LDD0583  [6]
 LDCM0267  AC147 HCT 116 C1425(1.21); C1430(1.21)  LDD0584  [6]
 LDCM0268  AC148 HCT 116 C1425(1.38); C1430(1.38)  LDD0585  [6]
 LDCM0269  AC149 HCT 116 C1425(1.21); C1430(1.21)  LDD0586  [6]
 LDCM0270  AC15 HCT 116 C1425(0.95); C1430(0.95)  LDD0587  [6]
 LDCM0271  AC150 HCT 116 C1425(0.90); C1430(0.90)  LDD0588  [6]
 LDCM0272  AC151 HCT 116 C1425(1.09); C1430(1.09)  LDD0589  [6]
 LDCM0273  AC152 HCT 116 C1425(1.11); C1430(1.11)  LDD0590  [6]
 LDCM0274  AC153 HCT 116 C1425(1.46); C1430(1.46)  LDD0591  [6]
 LDCM0621  AC154 HCT 116 C1425(1.21); C1430(1.21)  LDD2158  [6]
 LDCM0622  AC155 HCT 116 C1425(1.10); C1430(1.10)  LDD2159  [6]
 LDCM0623  AC156 HCT 116 C1425(0.92); C1430(0.92)  LDD2160  [6]
 LDCM0624  AC157 HCT 116 C1425(1.51); C1430(1.51)  LDD2161  [6]
 LDCM0276  AC17 HCT 116 C1785(1.30); C1425(1.37); C1430(1.37)  LDD0593  [6]
 LDCM0277  AC18 HCT 116 C1425(1.30); C1430(1.30); C1785(1.32)  LDD0594  [6]
 LDCM0278  AC19 HCT 116 C1785(1.41); C1425(1.94); C1430(1.94)  LDD0595  [6]
 LDCM0279  AC2 HCT 116 C309(0.86); C1430(1.07); C1785(1.24)  LDD0596  [6]
 LDCM0280  AC20 HCT 116 C1785(1.19); C1425(1.47); C1430(1.47)  LDD0597  [6]
 LDCM0281  AC21 HCT 116 C1785(1.39); C1425(1.61); C1430(1.61)  LDD0598  [6]
 LDCM0282  AC22 HCT 116 C1785(1.21); C1425(1.31); C1430(1.31)  LDD0599  [6]
 LDCM0283  AC23 HCT 116 C1785(1.21); C1425(1.64); C1430(1.64)  LDD0600  [6]
 LDCM0284  AC24 HCT 116 C1785(1.26); C1425(1.39); C1430(1.39)  LDD0601  [6]
 LDCM0285  AC25 HCT 116 C1785(1.01); C1425(1.07); C1430(1.09)  LDD0602  [6]
 LDCM0286  AC26 HCT 116 C1785(1.04); C1425(1.06); C1430(1.15)  LDD0603  [6]
 LDCM0287  AC27 HCT 116 C1785(1.15); C1425(1.22); C1430(1.32)  LDD0604  [6]
 LDCM0288  AC28 HCT 116 C1785(1.18); C1425(1.18); C1430(1.28)  LDD0605  [6]
 LDCM0289  AC29 HCT 116 C1785(1.20); C1425(1.40); C1430(1.40)  LDD0606  [6]
 LDCM0290  AC3 HCT 116 C1430(1.04); C1785(1.18); C309(1.90)  LDD0607  [6]
 LDCM0291  AC30 HCT 116 C1785(1.19); C1425(1.40); C1430(1.42)  LDD0608  [6]
 LDCM0292  AC31 HCT 116 C1785(1.19); C1425(1.31); C1430(1.50)  LDD0609  [6]
 LDCM0293  AC32 HCT 116 C1785(1.28); C1425(1.54); C1430(1.65)  LDD0610  [6]
 LDCM0294  AC33 HCT 116 C1785(1.27); C1430(1.33); C1425(1.38)  LDD0611  [6]
 LDCM0295  AC34 HCT 116 C1785(1.34); C1430(1.55); C1425(1.57)  LDD0612  [6]
 LDCM0296  AC35 HCT 116 C1425(0.60); C1430(0.60); C309(0.74); C1785(0.91)  LDD0613  [6]
 LDCM0297  AC36 HCT 116 C309(0.78); C1425(0.81); C1430(0.81); C1785(0.96)  LDD0614  [6]
 LDCM0298  AC37 HCT 116 C309(0.68); C1425(0.81); C1430(0.81); C1785(0.96)  LDD0615  [6]
 LDCM0299  AC38 HCT 116 C1785(0.91); C1425(0.92); C1430(0.92); C309(1.58)  LDD0616  [6]
 LDCM0300  AC39 HCT 116 C1425(0.71); C1430(0.71); C1785(1.03); C309(1.30)  LDD0617  [6]
 LDCM0301  AC4 HCT 116 C1785(1.11); C1430(1.11); C309(2.69)  LDD0618  [6]
 LDCM0302  AC40 HCT 116 C1425(0.92); C1430(0.92); C1785(1.14); C309(1.75)  LDD0619  [6]
 LDCM0303  AC41 HCT 116 C309(0.55); C1425(0.70); C1430(0.70); C1785(1.07)  LDD0620  [6]
 LDCM0304  AC42 HCT 116 C309(0.66); C1425(0.88); C1430(0.88); C1785(1.04)  LDD0621  [6]
 LDCM0305  AC43 HCT 116 C309(0.43); C1425(0.75); C1430(0.75); C1785(1.05)  LDD0622  [6]
 LDCM0306  AC44 HCT 116 C1425(0.72); C1430(0.72); C309(0.97); C1785(0.99)  LDD0623  [6]
 LDCM0307  AC45 HCT 116 C309(0.70); C1425(0.95); C1430(0.95); C1785(1.17)  LDD0624  [6]
 LDCM0308  AC46 HCT 116 C1785(0.97)  LDD0625  [6]
 LDCM0309  AC47 HCT 116 C1785(0.88)  LDD0626  [6]
 LDCM0310  AC48 HCT 116 C1785(0.89)  LDD0627  [6]
 LDCM0311  AC49 HCT 116 C1785(1.26)  LDD0628  [6]
 LDCM0312  AC5 HCT 116 C1430(1.16); C1785(1.25); C309(3.08)  LDD0629  [6]
 LDCM0313  AC50 HCT 116 C1785(1.17)  LDD0630  [6]
 LDCM0314  AC51 HCT 116 C1785(0.72)  LDD0631  [6]
 LDCM0315  AC52 HCT 116 C1785(1.09)  LDD0632  [6]
 LDCM0316  AC53 HCT 116 C1785(1.06)  LDD0633  [6]
 LDCM0317  AC54 HCT 116 C1785(1.20)  LDD0634  [6]
 LDCM0318  AC55 HCT 116 C1785(1.31)  LDD0635  [6]
 LDCM0319  AC56 HCT 116 C1785(1.57)  LDD0636  [6]
 LDCM0320  AC57 HCT 116 C1425(1.21); C1430(1.21); C1785(1.44)  LDD0637  [6]
 LDCM0321  AC58 HCT 116 C1425(1.22); C1430(1.22); C1785(1.98)  LDD0638  [6]
 LDCM0322  AC59 HCT 116 C1425(1.34); C1430(1.34); C1785(1.59)  LDD0639  [6]
 LDCM0323  AC6 HCT 116 C1425(1.01); C1430(1.01)  LDD0640  [6]
 LDCM0324  AC60 HCT 116 C1425(1.09); C1430(1.09); C1785(1.48)  LDD0641  [6]
 LDCM0325  AC61 HCT 116 C1425(1.07); C1430(1.07); C1785(1.85)  LDD0642  [6]
 LDCM0326  AC62 HCT 116 C1425(1.52); C1430(1.52); C1785(1.75)  LDD0643  [6]
 LDCM0327  AC63 HCT 116 C1425(1.08); C1430(1.08); C1785(1.79)  LDD0644  [6]
 LDCM0328  AC64 HCT 116 C1425(1.15); C1430(1.15); C1785(1.87)  LDD0645  [6]
 LDCM0329  AC65 HCT 116 C1425(0.73); C1430(0.73); C1785(1.37)  LDD0646  [6]
 LDCM0330  AC66 HCT 116 C1425(0.85); C1430(0.85); C1785(1.51)  LDD0647  [6]
 LDCM0331  AC67 HCT 116 C1425(0.84); C1430(0.84); C1785(1.44)  LDD0648  [6]
 LDCM0332  AC68 HCT 116 C1430(0.89); C1425(0.89)  LDD0649  [6]
 LDCM0333  AC69 HCT 116 C1430(1.01); C1425(1.02)  LDD0650  [6]
 LDCM0334  AC7 HCT 116 C1425(0.75); C1430(0.75)  LDD0651  [6]
 LDCM0335  AC70 HCT 116 C1425(1.08); C1430(1.09)  LDD0652  [6]
 LDCM0336  AC71 HCT 116 C1430(0.84); C1425(0.85)  LDD0653  [6]
 LDCM0337  AC72 HCT 116 C1425(1.00); C1430(1.03)  LDD0654  [6]
 LDCM0338  AC73 HCT 116 C1430(1.48); C1425(1.49)  LDD0655  [6]
 LDCM0339  AC74 HCT 116 C1425(1.00); C1430(1.02)  LDD0656  [6]
 LDCM0340  AC75 HCT 116 C1425(1.60); C1430(1.63)  LDD0657  [6]
 LDCM0341  AC76 HCT 116 C1425(1.14); C1430(1.20)  LDD0658  [6]
 LDCM0342  AC77 HCT 116 C1430(1.20); C1425(1.22)  LDD0659  [6]
 LDCM0343  AC78 HCT 116 C1425(0.91); C1430(0.91)  LDD0660  [6]
 LDCM0344  AC79 HCT 116 C1425(0.82); C1430(0.82)  LDD0661  [6]
 LDCM0345  AC8 HCT 116 C1425(0.76); C1430(0.76)  LDD0662  [6]
 LDCM0346  AC80 HCT 116 C1425(1.01); C1430(1.02)  LDD0663  [6]
 LDCM0347  AC81 HCT 116 C1430(0.81); C1425(0.81)  LDD0664  [6]
 LDCM0348  AC82 HCT 116 C1430(1.27); C1425(1.28)  LDD0665  [6]
 LDCM0349  AC83 HCT 116 C1430(1.67); C1785(1.71); C1425(1.74)  LDD0666  [6]
 LDCM0350  AC84 HCT 116 C1425(1.38); C1430(1.42); C1785(2.02)  LDD0667  [6]
 LDCM0351  AC85 HCT 116 C1430(1.20); C1425(1.28); C1785(1.59)  LDD0668  [6]
 LDCM0352  AC86 HCT 116 C1785(1.30); C1430(1.43); C1425(1.54)  LDD0669  [6]
 LDCM0353  AC87 HCT 116 C1785(1.20); C1430(1.35); C1425(1.40)  LDD0670  [6]
 LDCM0354  AC88 HCT 116 C1785(1.38); C1430(1.47); C1425(1.58)  LDD0671  [6]
 LDCM0355  AC89 HCT 116 C1785(1.60); C1430(1.83); C1425(1.91)  LDD0672  [6]
 LDCM0357  AC90 HCT 116 C1785(1.17); C1430(1.49); C1425(1.67)  LDD0674  [6]
 LDCM0358  AC91 HCT 116 C1785(1.65); C1430(1.82); C1425(1.89)  LDD0675  [6]
 LDCM0359  AC92 HCT 116 C1430(1.72); C1785(1.76); C1425(1.88)  LDD0676  [6]
 LDCM0360  AC93 HCT 116 C1430(1.38); C1425(1.41); C1785(1.51)  LDD0677  [6]
 LDCM0361  AC94 HCT 116 C1785(1.31); C1430(1.41); C1425(1.53)  LDD0678  [6]
 LDCM0362  AC95 HCT 116 C1430(1.43); C1785(1.49); C1425(1.50)  LDD0679  [6]
 LDCM0363  AC96 HCT 116 C1785(1.62); C1430(1.83); C1425(1.87)  LDD0680  [6]
 LDCM0364  AC97 HCT 116 C1430(1.61); C1425(1.67); C1785(1.70)  LDD0681  [6]
 LDCM0365  AC98 HCT 116 C1785(1.03); C1425(1.16); C1430(1.16)  LDD0682  [6]
 LDCM0366  AC99 HCT 116 C1785(0.76); C1425(0.78); C1430(0.78)  LDD0683  [6]
 LDCM0248  AKOS034007472 HCT 116 C1425(0.88); C1430(0.88)  LDD0565  [6]
 LDCM0356  AKOS034007680 HCT 116 C1425(0.85); C1430(0.85)  LDD0673  [6]
 LDCM0275  AKOS034007705 HCT 116 C1425(1.31); C1430(1.31)  LDD0592  [6]
 LDCM0020  ARS-1620 HCC44 C1398(1.29); C1411(1.29); C1425(1.02); C1430(1.02)  LDD2171  [6]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [10]
 LDCM0367  CL1 HCT 116 C1785(0.79); C1425(0.89); C1430(0.89)  LDD0684  [6]
 LDCM0368  CL10 HCT 116 C1785(0.73); C1425(1.29); C1430(1.29)  LDD0685  [6]
 LDCM0369  CL100 HCT 116 C1785(1.12); C1430(1.26); C309(1.55)  LDD0686  [6]
 LDCM0370  CL101 HCT 116 C1425(1.02); C1430(1.02)  LDD0687  [6]
 LDCM0371  CL102 HCT 116 C1425(0.99); C1430(0.99)  LDD0688  [6]
 LDCM0372  CL103 HCT 116 C1425(1.31); C1430(1.31)  LDD0689  [6]
 LDCM0373  CL104 HCT 116 C1425(1.35); C1430(1.35)  LDD0690  [6]
 LDCM0374  CL105 HCT 116 C1785(1.56); C1425(1.91); C1430(1.91)  LDD0691  [6]
 LDCM0375  CL106 HCT 116 C1785(1.77); C1425(2.04); C1430(2.04)  LDD0692  [6]
 LDCM0376  CL107 HCT 116 C1425(1.47); C1430(1.47); C1785(1.52)  LDD0693  [6]
 LDCM0377  CL108 HCT 116 C1785(1.93); C1425(2.20); C1430(2.20)  LDD0694  [6]
 LDCM0378  CL109 HCT 116 C1785(1.40); C1425(1.91); C1430(1.91)  LDD0695  [6]
 LDCM0379  CL11 HCT 116 C1785(0.60); C1425(1.02); C1430(1.02)  LDD0696  [6]
 LDCM0380  CL110 HCT 116 C1785(1.60); C1425(2.25); C1430(2.25)  LDD0697  [6]
 LDCM0381  CL111 HCT 116 C1785(1.40); C1425(2.11); C1430(2.11)  LDD0698  [6]
 LDCM0382  CL112 HCT 116 C1785(1.03); C1430(1.18); C1425(1.22)  LDD0699  [6]
 LDCM0383  CL113 HCT 116 C1785(1.13); C1425(1.35); C1430(1.56)  LDD0700  [6]
 LDCM0384  CL114 HCT 116 C1785(1.12); C1430(1.23); C1425(1.26)  LDD0701  [6]
 LDCM0385  CL115 HCT 116 C1785(1.19); C1430(1.23); C1425(1.25)  LDD0702  [6]
 LDCM0386  CL116 HCT 116 C1785(1.17); C1425(1.24); C1430(1.32)  LDD0703  [6]
 LDCM0387  CL117 HCT 116 C1425(1.35); C1430(1.35); C1785(1.56); C309(2.41)  LDD0704  [6]
 LDCM0388  CL118 HCT 116 C309(0.64); C1425(0.83); C1430(0.83); C1785(1.10)  LDD0705  [6]
 LDCM0389  CL119 HCT 116 C309(0.56); C1425(0.95); C1430(0.95); C1785(1.05)  LDD0706  [6]
 LDCM0390  CL12 HCT 116 C1785(0.74); C1425(1.58); C1430(1.58)  LDD0707  [6]
 LDCM0391  CL120 HCT 116 C309(0.58); C1425(0.72); C1430(0.72); C1785(0.92)  LDD0708  [6]
 LDCM0392  CL121 HCT 116 C1785(1.24)  LDD0709  [6]
 LDCM0393  CL122 HCT 116 C1785(1.04)  LDD0710  [6]
 LDCM0394  CL123 HCT 116 C1785(1.22)  LDD0711  [6]
 LDCM0395  CL124 HCT 116 C1785(1.29)  LDD0712  [6]
 LDCM0396  CL125 HCT 116 C1425(1.05); C1430(1.05); C1785(1.20)  LDD0713  [6]
 LDCM0397  CL126 HCT 116 C1425(1.28); C1430(1.28); C1785(1.51)  LDD0714  [6]
 LDCM0398  CL127 HCT 116 C1425(1.11); C1430(1.11); C1785(1.89)  LDD0715  [6]
 LDCM0399  CL128 HCT 116 C1425(1.21); C1430(1.21); C1785(1.61)  LDD0716  [6]
 LDCM0400  CL13 HCT 116 C1785(0.69); C1425(1.27); C1430(1.27)  LDD0717  [6]
 LDCM0401  CL14 HCT 116 C1785(0.80); C1425(1.26); C1430(1.26)  LDD0718  [6]
 LDCM0402  CL15 HCT 116 C1785(0.69); C1425(1.20); C1430(1.20)  LDD0719  [6]
 LDCM0403  CL16 HCT 116 C1425(1.14); C1430(1.14)  LDD0720  [6]
 LDCM0404  CL17 HCT 116 C1425(1.05); C1430(1.05); C1785(1.05)  LDD0721  [6]
 LDCM0405  CL18 HCT 116 C1785(0.89); C1425(1.07); C1430(1.07)  LDD0722  [6]
 LDCM0406  CL19 HCT 116 C1785(1.02); C1425(1.20); C1430(1.20)  LDD0723  [6]
 LDCM0407  CL2 HCT 116 C1785(0.74); C1425(0.95); C1430(0.95)  LDD0724  [6]
 LDCM0408  CL20 HCT 116 C1425(1.19); C1430(1.19); C1785(1.20)  LDD0725  [6]
 LDCM0409  CL21 HCT 116 C1785(1.01); C1425(1.03); C1430(1.03)  LDD0726  [6]
 LDCM0410  CL22 HCT 116 C1785(1.16); C1425(1.29); C1430(1.29)  LDD0727  [6]
 LDCM0411  CL23 HCT 116 C1425(1.01); C1430(1.01); C1785(1.37)  LDD0728  [6]
 LDCM0412  CL24 HCT 116 C1785(1.04); C1425(1.05); C1430(1.05)  LDD0729  [6]
 LDCM0413  CL25 HCT 116 C1425(0.97); C1430(0.97); C1785(0.86)  LDD0730  [6]
 LDCM0414  CL26 HCT 116 C1425(1.26); C1430(1.26); C1785(0.97)  LDD0731  [6]
 LDCM0415  CL27 HCT 116 C1425(1.04); C1430(1.04); C1785(0.97)  LDD0732  [6]
 LDCM0416  CL28 HCT 116 C1425(1.10); C1430(1.10); C1785(1.01)  LDD0733  [6]
 LDCM0417  CL29 HCT 116 C1425(1.07); C1430(1.07); C1785(1.20)  LDD0734  [6]
 LDCM0418  CL3 HCT 116 C1425(1.00); C1430(1.00); C1785(0.80)  LDD0735  [6]
 LDCM0419  CL30 HCT 116 C1425(1.04); C1430(1.04); C1785(0.94)  LDD0736  [6]
 LDCM0420  CL31 HCT 116 C1425(1.25); C1430(1.25); C1785(1.21); C309(0.89)  LDD0737  [6]
 LDCM0421  CL32 HCT 116 C1425(1.06); C1430(1.06); C309(0.72)  LDD0738  [6]
 LDCM0422  CL33 HCT 116 C1425(0.93); C1430(0.93); C309(0.73)  LDD0739  [6]
 LDCM0423  CL34 HCT 116 C1425(1.31); C1430(1.31); C309(0.75)  LDD0740  [6]
 LDCM0424  CL35 HCT 116 C1425(1.32); C1430(1.32); C309(1.14)  LDD0741  [6]
 LDCM0425  CL36 HCT 116 C1425(1.57); C1430(1.57); C309(0.63)  LDD0742  [6]
 LDCM0426  CL37 HCT 116 C1425(1.10); C1430(1.10); C309(0.84)  LDD0743  [6]
 LDCM0428  CL39 HCT 116 C1425(1.20); C1430(1.20); C309(0.62)  LDD0745  [6]
 LDCM0429  CL4 HCT 116 C1425(0.90); C1430(0.90); C1785(0.77)  LDD0746  [6]
 LDCM0430  CL40 HCT 116 C1425(1.03); C1430(1.03); C309(0.57)  LDD0747  [6]
 LDCM0431  CL41 HCT 116 C1425(1.30); C1430(1.30); C309(0.50)  LDD0748  [6]
 LDCM0432  CL42 HCT 116 C1425(1.17); C1430(1.17); C309(0.55)  LDD0749  [6]
 LDCM0433  CL43 HCT 116 C1425(1.30); C1430(1.30); C309(0.47)  LDD0750  [6]
 LDCM0434  CL44 HCT 116 C1425(1.26); C1430(1.26); C309(0.76)  LDD0751  [6]
 LDCM0435  CL45 HCT 116 C1425(1.22); C1430(1.22); C309(0.88)  LDD0752  [6]
 LDCM0436  CL46 HCT 116 C1425(1.06); C1430(1.06); C309(0.96)  LDD0753  [6]
 LDCM0437  CL47 HCT 116 C1425(1.02); C1430(1.02); C309(1.13)  LDD0754  [6]
 LDCM0438  CL48 HCT 116 C1425(1.15); C1430(1.15); C309(1.44)  LDD0755  [6]
 LDCM0439  CL49 HCT 116 C1425(1.32); C1430(1.32); C309(1.04)  LDD0756  [6]
 LDCM0440  CL5 HCT 116 C1425(1.24); C1430(1.24); C1785(0.68)  LDD0757  [6]
 LDCM0441  CL50 HCT 116 C1425(1.22); C1430(1.22); C309(1.22)  LDD0758  [6]
 LDCM0442  CL51 HCT 116 C1425(0.93); C1430(0.93); C309(0.94)  LDD0759  [6]
 LDCM0443  CL52 HCT 116 C1425(1.07); C1430(1.07); C309(1.34)  LDD0760  [6]
 LDCM0444  CL53 HCT 116 C1425(1.26); C1430(1.26); C309(1.68)  LDD0761  [6]
 LDCM0445  CL54 HCT 116 C1425(1.38); C1430(1.38); C309(0.88)  LDD0762  [6]
 LDCM0446  CL55 HCT 116 C1425(1.20); C1430(1.20); C309(0.96)  LDD0763  [6]
 LDCM0447  CL56 HCT 116 C1425(1.08); C1430(1.08); C309(1.27)  LDD0764  [6]
 LDCM0448  CL57 HCT 116 C1425(1.16); C1430(1.16); C309(1.26)  LDD0765  [6]
 LDCM0449  CL58 HCT 116 C1425(1.14); C1430(1.14); C309(1.06)  LDD0766  [6]
 LDCM0450  CL59 HCT 116 C1425(1.33); C1430(1.33); C309(1.35)  LDD0767  [6]
 LDCM0451  CL6 HCT 116 C1425(1.19); C1430(1.19); C1785(0.82)  LDD0768  [6]
 LDCM0452  CL60 HCT 116 C1425(1.45); C1430(1.45); C309(1.13)  LDD0769  [6]
 LDCM0453  CL61 HCT 116 C1425(1.09); C1430(1.09); C1785(1.09); C309(1.59)  LDD0770  [6]
 LDCM0454  CL62 HCT 116 C1425(1.03); C1430(1.03); C1785(1.29); C309(2.08)  LDD0771  [6]
 LDCM0455  CL63 HCT 116 C1425(1.11); C1430(1.11); C1785(1.29); C309(1.94)  LDD0772  [6]
 LDCM0456  CL64 HCT 116 C1425(1.16); C1430(1.16); C1785(1.43); C309(1.51)  LDD0773  [6]
 LDCM0457  CL65 HCT 116 C1425(1.03); C1430(1.03); C1785(1.25); C309(1.44)  LDD0774  [6]
 LDCM0458  CL66 HCT 116 C1425(0.99); C1430(0.99); C1785(1.53); C309(1.77)  LDD0775  [6]
 LDCM0459  CL67 HCT 116 C1425(1.22); C1430(1.22); C1785(1.37); C309(1.09)  LDD0776  [6]
 LDCM0460  CL68 HCT 116 C1425(1.10); C1430(1.10); C1785(1.34); C309(1.39)  LDD0777  [6]
 LDCM0461  CL69 HCT 116 C1425(1.14); C1430(1.14); C1785(1.40); C309(1.59)  LDD0778  [6]
 LDCM0462  CL7 HCT 116 C1425(1.24); C1430(1.24); C1785(0.72)  LDD0779  [6]
 LDCM0463  CL70 HCT 116 C1425(1.04); C1430(1.04); C1785(1.52); C309(1.27)  LDD0780  [6]
 LDCM0464  CL71 HCT 116 C1425(1.07); C1430(1.07); C1785(1.14); C309(1.40)  LDD0781  [6]
 LDCM0465  CL72 HCT 116 C1425(1.38); C1430(1.38); C1785(0.98); C309(1.26)  LDD0782  [6]
 LDCM0466  CL73 HCT 116 C1425(0.93); C1430(0.93); C1785(1.77); C309(1.09)  LDD0783  [6]
 LDCM0467  CL74 HCT 116 C1425(1.27); C1430(1.27); C1785(1.46); C309(1.05)  LDD0784  [6]
 LDCM0469  CL76 HCT 116 C1785(1.03); C309(1.20)  LDD0786  [6]
 LDCM0470  CL77 HCT 116 C1785(1.61); C309(1.01)  LDD0787  [6]
 LDCM0471  CL78 HCT 116 C1785(1.13); C309(0.81)  LDD0788  [6]
 LDCM0472  CL79 HCT 116 C1785(1.39); C309(1.36)  LDD0789  [6]
 LDCM0473  CL8 HCT 116 C1425(0.98); C1430(0.98); C1785(0.79)  LDD0790  [6]
 LDCM0474  CL80 HCT 116 C1785(1.34); C309(1.30)  LDD0791  [6]
 LDCM0475  CL81 HCT 116 C1785(1.12); C309(1.03)  LDD0792  [6]
 LDCM0476  CL82 HCT 116 C1785(1.68); C309(1.81)  LDD0793  [6]
 LDCM0477  CL83 HCT 116 C1785(1.30); C309(1.67)  LDD0794  [6]
 LDCM0478  CL84 HCT 116 C1785(1.60); C309(2.55)  LDD0795  [6]
 LDCM0479  CL85 HCT 116 C1785(1.06); C309(1.90)  LDD0796  [6]
 LDCM0480  CL86 HCT 116 C1785(1.07); C309(2.07)  LDD0797  [6]
 LDCM0481  CL87 HCT 116 C1785(1.24); C309(1.77)  LDD0798  [6]
 LDCM0482  CL88 HCT 116 C1785(1.42); C309(2.35)  LDD0799  [6]
 LDCM0483  CL89 HCT 116 C1785(2.01); C309(1.63)  LDD0800  [6]
 LDCM0484  CL9 HCT 116 C1425(1.04); C1430(1.04); C1785(0.75)  LDD0801  [6]
 LDCM0485  CL90 HCT 116 C1785(0.99); C309(0.87)  LDD0802  [6]
 LDCM0486  CL91 HCT 116 C1430(1.31); C1785(1.18); C309(0.87)  LDD0803  [6]
 LDCM0487  CL92 HCT 116 C1430(1.04); C1785(1.04); C309(0.68)  LDD0804  [6]
 LDCM0488  CL93 HCT 116 C1430(1.03); C1785(1.04); C309(0.61)  LDD0805  [6]
 LDCM0489  CL94 HCT 116 C1430(1.22); C1785(1.24); C309(0.48)  LDD0806  [6]
 LDCM0490  CL95 HCT 116 C1430(1.02); C1785(1.32); C309(0.78)  LDD0807  [6]
 LDCM0491  CL96 HCT 116 C1430(1.17); C1785(1.27); C309(0.73)  LDD0808  [6]
 LDCM0492  CL97 HCT 116 C1430(1.18); C1785(1.28); C309(0.88)  LDD0809  [6]
 LDCM0493  CL98 HCT 116 C1430(0.96); C1785(1.31); C309(1.98)  LDD0810  [6]
 LDCM0494  CL99 HCT 116 C1430(1.32); C1785(1.59); C309(1.54)  LDD0811  [6]
 LDCM0027  Dopamine HEK-293T 5.61  LDD0179  [1]
 LDCM0468  Fragment33 HCT 116 C1425(0.96); C1430(0.96); C1785(1.60); C309(1.83)  LDD0785  [6]
 LDCM0427  Fragment51 HCT 116 C1425(1.37); C1430(1.37); C309(0.60)  LDD0744  [6]
 LDCM0116  HHS-0101 DM93 Y663(0.61)  LDD0264  [5]
 LDCM0117  HHS-0201 DM93 Y663(0.78)  LDD0265  [5]
 LDCM0118  HHS-0301 DM93 Y663(0.46)  LDD0266  [5]
 LDCM0119  HHS-0401 DM93 Y663(0.79)  LDD0267  [5]
 LDCM0120  HHS-0701 DM93 Y663(0.35)  LDD0268  [5]
 LDCM0107  IAA HeLa N.A.  LDD0221  [10]
 LDCM0022  KB02 HCT 116 C1425(3.84); C1430(3.84)  LDD0080  [6]
 LDCM0023  KB03 HCT 116 C1425(2.32); C1430(2.32)  LDD0081  [6]
 LDCM0024  KB05 HCT 116 C1425(4.54); C1430(4.54)  LDD0082  [6]
 LDCM0109  NEM HeLa N.A.  LDD0227  [10]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C755(0.92); C671(1.26); C332(1.60)  LDD2099  [4]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C755(0.40); C671(0.95); C332(0.99)  LDD2107  [4]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C755(0.86); C671(0.73); C332(0.74)  LDD2109  [4]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C755(0.98); C671(0.98)  LDD2111  [4]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C671(1.36)  LDD2119  [4]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C755(0.83)  LDD2123  [4]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C671(0.65)  LDD2127  [4]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C755(1.52); C671(0.59); C332(1.39)  LDD2137  [4]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C755(0.96); C332(0.43)  LDD2140  [4]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C671(0.66)  LDD2146  [4]
 LDCM0021  THZ1 HCT 116 C1398(1.29); C1411(1.29); C1425(1.02); C1430(1.02)  LDD2173  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

GPCR
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Probable G-protein coupled receptor 152 (GPR152) G-protein coupled receptor 1 family Q8TDT2
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
B-cell antigen receptor complex-associated protein alpha chain (CD79A) . P11912
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ubiquilin-1 (UBQLN1) . Q9UMX0

The Drug(s) Related To This Target

Investigative
Click To Hide/Show 1 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Lanoteplase . DB06245

References

1 A chemical probe unravels the reactive proteome of health-associated catechols. Chem Sci. 2023 Jul 22;14(32):8635-8643. doi: 10.1039/d3sc00888f. eCollection 2023 Aug 16.
Mass spectrometry data entry: PXD043348
2 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
3 A chemical proteomics approach for global mapping of functional lysines on cell surface of living cell. Nat Commun. 2024 Apr 8;15(1):2997. doi: 10.1038/s41467-024-47033-w.
Mass spectrometry data entry: PXD042888
4 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
5 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
6 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
7 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
8 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
9 Site-Specific Activity-Based Protein Profiling Using Phosphonate Handles. Mol Cell Proteomics. 2023 Jan;22(1):100455. doi: 10.1016/j.mcpro.2022.100455. Epub 2022 Nov 24.
Mass spectrometry data entry: PXD036569
10 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
11 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010
12 Global targeting of functional tyrosines using sulfur-triazole exchange chemistry. Nat Chem Biol. 2020 Feb;16(2):150-159. doi: 10.1038/s41589-019-0404-5. Epub 2019 Nov 25.
13 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587