Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | HRP | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 15 uM | |||||
| Criteria | Quantification: Probe vs DMSO | |||||
| Quantitative Method |
LFQ
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP07227 | Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) | 27.8 | ||||
| LDTP09517 | Ubiquitin carboxyl-terminal hydrolase 33 (USP33) | 25.9 | ||||
| LDTP00598 | Serine palmitoyltransferase 2 (SPTLC2) | 23.1 | ||||
| LDTP00968 | Acyl-CoA (8-3)-desaturase (FADS1) | 21.9 | ||||
| LDTP06270 | Signal peptidase complex subunit 2 (SPCS2) | 20.6 | ||||
| LDTP03540 | Heme oxygenase 2 (HMOX2) | 19.5 | ||||
| LDTP08378 | Serine/threonine-protein kinase VRK2 (VRK2) | 16.1 | ||||
| LDTP02000 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) | 8.4 | ||||
| LDTP01004 | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B) | 8.3 | ||||
| LDTP05874 | Disintegrin and metalloproteinase domain-containing protein 15 (ADAM15) | 7.9 | ||||
| LDTP12279 | Endoplasmic reticulum transmembrane helix translocase (ATP13A1) | 7.9 | ||||
| LDTP01707 | Thioredoxin domain-containing protein 12 (TXNDC12) | 6.6 | ||||
| LDTP09188 | Lysophosphatidylcholine acyltransferase 1 (LPCAT1) | 6.6 | ||||
| LDTP08799 | Lysophosphatidylserine lipase ABHD12 (ABHD12) | 5.6 | ||||
| LDTP02935 | Tyrosine-protein phosphatase non-receptor type 1 (PTPN1) | 5.6 | ||||
| LDTP04203 | Phosphatidylserine synthase 1 (PTDSS1) | 5.5 | ||||
| LDTP00544 | Sphingolipid delta(4)-desaturase DES1 (DEGS1) | 4.9 | ||||
| LDTP06104 | Peptidyl-prolyl cis-trans isomerase FKBP8 (FKBP8) | 4.9 | ||||
| LDTP12886 | Glycerophosphodiester phosphodiesterase 1 (GDE1) | 4.9 | ||||
| LDTP06145 | Protein disulfide-isomerase A5 (PDIA5) | 4.7 | ||||
| LDTP00089 | Glycerol-3-phosphate phosphatase (PGP) | 4.5 | ||||
| LDTP16105 | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 (TYW1) | 4.4 | ||||
| LDTP10245 | Dehydrodolichyl diphosphate synthase complex subunit NUS1 (NUS1) | 4.1 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP12191 | Vezatin (VEZT) | 47.1 | ||||
| LDTP06633 | Reticulon-1 (RTN1) | 35.4 | ||||
| LDTP13018 | Stromal interaction molecule 2 (STIM2) | 17.5 | ||||
| LDTP04770 | Syntaxin-17 (STX17) | 12.5 | ||||
| LDTP08897 | Macoilin (MACO1) | 12.2 | ||||
| LDTP04309 | Nuclear pore complex protein Nup153 (NUP153) | 9.8 | ||||
| LDTP10669 | Melanoma inhibitory activity protein 2 (MIA2) | 9.1 | ||||
| LDTP09352 | DnaJ homolog subfamily B member 14 (DNAJB14) | 8.9 | ||||
| LDTP10181 | Protein Aster-A (GRAMD1A) | 8.4 | ||||
| LDTP06902 | mRNA export factor GLE1 (GLE1) | 7.2 | ||||
| LDTP04227 | Guided entry of tail-anchored proteins factor CAMLG (CAMLG) | 7.0 | ||||
| LDTP08040 | Zinc finger FYVE domain-containing protein 16 (ZFYVE16) | 7.0 | ||||
| LDTP02122 | Integrin beta-1 (ITGB1) | 5.7 | ||||
| LDTP01454 | SUN domain-containing protein 1 (SUN1) | 5.2 | ||||
| LDTP09204 | Nucleoporin NUP35 (NUP35) | 5.2 | ||||
| LDTP07002 | Transport and Golgi organization protein 1 homolog (MIA3) | 4.6 | ||||
| LDTP04866 | Protein transport protein Sec61 subunit beta (SEC61B) | 4.2 | ||||
| LDTP11161 | Extended synaptotagmin-1 (ESYT1) | 4.0 | ||||
Transcription factor
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP00461 | Transcription regulator protein BACH1 (BACH1) | 8.1 | ||||
| LDTP02970 | Cyclic AMP-dependent transcription factor ATF-6 alpha (ATF6) | 6.5 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP01210 | Transforming acidic coiled-coil-containing protein 1 (TACC1) | 109.5 | ||||
| LDTP09806 | UBX domain-containing protein 4 (UBXN4) | 38.1 | ||||
| LDTP01522 | Reticulon-3 (RTN3) | 34.0 | ||||
| LDTP09702 | Nesprin-2 (SYNE2) | 22.0 | ||||
| LDTP00512 | Protein transport protein Sec16A (SEC16A) | 21.1 | ||||
| LDTP08364 | Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) | 17.1 | ||||
| LDTP18272 | Transmembrane protein 209 (TMEM209) | 16.7 | ||||
| LDTP02535 | Laminin subunit gamma-1 (LAMC1) | 11.0 | ||||
| LDTP08902 | CDGSH iron-sulfur domain-containing protein 2 (CISD2) | 9.9 | ||||
| LDTP09837 | A-kinase anchor protein 1, mitochondrial (AKAP1) | 9.7 | ||||
| LDTP03426 | Protein ITPRID2 (ITPRID2) | 9.0 | ||||
| LDTP05382 | A-kinase anchor protein 12 (AKAP12) | 8.6 | ||||
| LDTP07345 | Cell division cycle-associated protein 2 (CDCA2) | 6.8 | ||||
| LDTP02230 | Laminin subunit beta-1 (LAMB1) | 6.6 | ||||
| LDTP13913 | Inner nuclear membrane protein Man1 (LEMD3) | 5.7 | ||||
| LDTP14217 | Lipid droplet-regulating VLDL assembly factor AUP1 (AUP1) | 5.5 | ||||
| LDTP09787 | Nicastrin (NCSTN) | 5.4 | ||||
| LDTP13241 | LIM domain-containing protein 1 (LIMD1) | 5.4 | ||||
| LDTP15840 | Tetratricopeptide repeat protein 1 (TTC1) | 4.8 | ||||
| LDTP13507 | BAG family molecular chaperone regulator 5 (BAG5) | 4.7 | ||||
| LDTP16285 | Transducin beta-like protein 2 (TBL2) | 4.6 | ||||
| LDTP08535 | MAP7 domain-containing protein 3 (MAP7D3) | 4.4 | ||||
| LDTP14228 | Transforming acidic coiled-coil-containing protein 3 (TACC3) | 4.2 | ||||
| LDTP02282 | Collagen alpha-2(IV) chain (COL4A2) | 4.2 | ||||
| LDTP09137 | Trinucleotide repeat-containing gene 6A protein (TNRC6A) | 4.2 | ||||
| LDTP10431 | Vesicle-trafficking protein SEC22a (SEC22A) | 4.1 | ||||
| LDTP19744 | Uncharacterized protein FAM241A (FAM241A) | 4.1 | ||||