Details of the Target

General Information of Target

Target ID LDTP14676
Target Name Guanine nucleotide-binding protein-like 1 (GNL1)
Gene Name GNL1
Gene ID 2794
Synonyms
HSR1; Guanine nucleotide-binding protein-like 1; GTP-binding protein HSR1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MALKWTTVLLIQLSFYFSSGSCGKVLVWAAEYSLWMNMKTILKELVQRGHEVTVLASSAS
ILFDPNDSSTLKLEVYPTSLTKTEFENIIMQLVKRLSEIQKDTFWLPFSQEQEILWAIND
IIRNFCKDVVSNKKLMKKLQESRFDIVFADAYLPCGELLAELFNIPFVYSHSFSPGYSFE
RHSGGFIFPPSYVPVVMSKLSDQMTFMERVKNMLYVLYFDFWFQIFNMKKWDQFYSEVLG
RPTTLSETMRKADIWLMRNSWNFKFPHPFLPNVDFVGGLHCKPAKPLPKEMEEFVQSSGE
NGVVVFSLGSMVSNMTEERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQND
LLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRVDFNTMS
STDLLNALKTVINDPSYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAH
NLTWFQYHSLDVIGFLLACVATVLFIITKCCLFCFWKFARKGKKGKRD
Target Bioclass
Enzyme
Family
TRAFAC class YlqF/YawG GTPase family
Function Possible regulatory or functional link with the histocompatibility cluster.
Uniprot ID
P36915
Ensemble ID
ENST00000376621.8
HGNC ID
HGNC:4413

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
A2780 SNV: p.S374F DBIA    Probe Info 
DU145 SNV: p.V212M DBIA    Probe Info 
HCT15 SNV: p.G603D DBIA    Probe Info 
HT SNV: p.S524G DBIA    Probe Info 
ICC8 SNV: p.P247A DBIA    Probe Info 
LS180 SNV: p.L456R .
NCIH1793 SNV: p.G29W .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 21 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		12.50  LDD0402  [1]
TH211
 Probe Info  		Y441(20.00); Y446(15.11); Y432(12.84)  LDD0260  [2]
STPyne
 Probe Info  		K167(10.00)  LDD0277  [3]
ONAyne
 Probe Info  		N.A.  LDD0273  [3]
IPM
 Probe Info  		N.A.  LDD0241  [4]
Probe 1
 Probe Info  		Y81(33.85); Y121(9.22); Y155(28.14); Y163(22.76)  LDD3495  [5]
HHS-475
 Probe Info  		Y76(1.27)  LDD0264  [6]
HHS-465
 Probe Info  		Y170(4.57)  LDD2237  [7]
DBIA
 Probe Info  		C607(0.97)  LDD0078  [8]
ATP probe
 Probe Info  		N.A.  LDD0199  [9]
4-Iodoacetamidophenylacetylene
 Probe Info  		C294(0.00); C365(0.00); C517(0.00); C607(0.00)  LDD0038  [10]
IA-alkyne
 Probe Info  		C410(0.00); C365(0.00)  LDD0032  [11]
Lodoacetamide azide
 Probe Info  		C294(0.00); C365(0.00); C517(0.00); C410(0.00)  LDD0037  [10]
NAIA_4
 Probe Info  		N.A.  LDD2226  [12]
TFBX
 Probe Info  		N.A.  LDD0027  [13]
Compound 10
 Probe Info  		N.A.  LDD2216  [14]
PF-06672131
 Probe Info  		C365(0.00); C412(0.00)  LDD0017  [15]
Acrolein
 Probe Info  		N.A.  LDD0217  [16]
W1
 Probe Info  		N.A.  LDD0236  [4]
AOyne
 Probe Info  		10.10  LDD0443  [17]
NAIA_5
 Probe Info  		C294(0.00); C517(0.00); C365(0.00)  LDD2223  [12]
PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STS-2
 Probe Info  		N.A.  LDD0139  [18]
VE-P
 Probe Info  		N.A.  LDD0396  [19]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C365(1.10); C474(0.62); C479(0.62); C607(1.04)  LDD0531  [8]
 LDCM0215  AC10 HCT 116 C365(1.14); C410(0.75); C412(0.75); C474(0.68)  LDD0532  [8]
 LDCM0216  AC100 HCT 116 C365(0.79); C474(0.72); C479(0.75); C607(0.87)  LDD0533  [8]
 LDCM0217  AC101 HCT 116 C365(0.85); C474(0.68); C479(0.68); C607(0.90)  LDD0534  [8]
 LDCM0218  AC102 HCT 116 C365(0.94); C474(0.76); C479(0.80); C607(0.95)  LDD0535  [8]
 LDCM0219  AC103 HCT 116 C365(0.81); C474(0.63); C479(0.65); C607(1.08)  LDD0536  [8]
 LDCM0220  AC104 HCT 116 C365(0.89); C474(0.66); C479(0.72); C607(0.97)  LDD0537  [8]
 LDCM0221  AC105 HCT 116 C365(0.82); C474(0.65); C479(0.68); C607(1.17)  LDD0538  [8]
 LDCM0222  AC106 HCT 116 C365(0.76); C474(0.71); C479(0.76); C607(1.21)  LDD0539  [8]
 LDCM0223  AC107 HCT 116 C365(0.78); C474(0.75); C479(0.78); C607(1.22)  LDD0540  [8]
 LDCM0224  AC108 HCT 116 C365(0.84); C474(0.66); C479(0.72); C607(0.88)  LDD0541  [8]
 LDCM0225  AC109 HCT 116 C365(0.90); C474(0.76); C479(0.78); C607(0.77)  LDD0542  [8]
 LDCM0226  AC11 HCT 116 C365(1.15); C410(0.54); C412(0.54); C474(0.72)  LDD0543  [8]
 LDCM0227  AC110 HCT 116 C365(0.88); C474(0.72); C479(0.70); C607(0.85)  LDD0544  [8]
 LDCM0228  AC111 HCT 116 C365(0.80); C474(0.67); C479(0.71); C607(0.83)  LDD0545  [8]
 LDCM0229  AC112 HCT 116 C365(0.87); C474(0.62); C479(0.65); C607(0.96)  LDD0546  [8]
 LDCM0230  AC113 HCT 116 C365(1.11); C474(1.12); C479(1.04)  LDD0547  [8]
 LDCM0231  AC114 HCT 116 C365(0.96); C474(0.90); C479(0.82)  LDD0548  [8]
 LDCM0232  AC115 HCT 116 C365(0.88); C474(0.76); C479(0.74)  LDD0549  [8]
 LDCM0233  AC116 HCT 116 C365(0.82); C474(0.81); C479(0.80)  LDD0550  [8]
 LDCM0234  AC117 HCT 116 C365(0.89); C474(0.84); C479(0.82)  LDD0551  [8]
 LDCM0235  AC118 HCT 116 C365(0.93); C474(0.92); C479(0.87)  LDD0552  [8]
 LDCM0236  AC119 HCT 116 C365(0.91); C474(0.90); C479(0.92)  LDD0553  [8]
 LDCM0237  AC12 HCT 116 C365(1.33); C410(0.73); C412(0.73); C474(0.86)  LDD0554  [8]
 LDCM0238  AC120 HCT 116 C365(0.88); C474(0.88); C479(0.82)  LDD0555  [8]
 LDCM0239  AC121 HCT 116 C365(0.91); C474(0.90); C479(0.90)  LDD0556  [8]
 LDCM0240  AC122 HCT 116 C365(0.79); C474(0.79); C479(0.77)  LDD0557  [8]
 LDCM0241  AC123 HCT 116 C365(0.99); C474(0.79); C479(0.76)  LDD0558  [8]
 LDCM0242  AC124 HCT 116 C365(0.86); C474(1.03); C479(1.01)  LDD0559  [8]
 LDCM0243  AC125 HCT 116 C365(0.96); C474(1.00); C479(0.99)  LDD0560  [8]
 LDCM0244  AC126 HCT 116 C365(0.85); C474(0.79); C479(0.81)  LDD0561  [8]
 LDCM0245  AC127 HCT 116 C365(0.84); C474(0.82); C479(0.75)  LDD0562  [8]
 LDCM0246  AC128 HCT 116 C365(1.22); C474(0.96); C479(0.96); C607(1.02)  LDD0563  [8]
 LDCM0247  AC129 HCT 116 C365(1.21); C474(1.15); C479(1.15); C607(1.02)  LDD0564  [8]
 LDCM0249  AC130 HCT 116 C365(1.07); C474(0.80); C479(0.80); C607(0.91)  LDD0566  [8]
 LDCM0250  AC131 HCT 116 C365(1.15); C474(1.20); C479(1.20); C607(1.04)  LDD0567  [8]
 LDCM0251  AC132 HCT 116 C365(1.00); C474(1.19); C479(1.19); C607(1.11)  LDD0568  [8]
 LDCM0252  AC133 HCT 116 C365(1.00); C474(0.98); C479(0.98); C607(1.00)  LDD0569  [8]
 LDCM0253  AC134 HCT 116 C365(1.01); C474(0.97); C479(0.97); C607(0.94)  LDD0570  [8]
 LDCM0254  AC135 HCT 116 C365(1.06); C474(0.92); C479(0.92); C607(1.01)  LDD0571  [8]
 LDCM0255  AC136 HCT 116 C365(0.86); C474(0.89); C479(0.89); C607(0.96)  LDD0572  [8]
 LDCM0256  AC137 HCT 116 C365(0.88); C474(0.99); C479(0.99); C607(0.95)  LDD0573  [8]
 LDCM0257  AC138 HCT 116 C365(0.91); C474(0.94); C479(0.94); C607(0.83)  LDD0574  [8]
 LDCM0258  AC139 HCT 116 C365(0.88); C474(0.96); C479(0.96); C607(0.99)  LDD0575  [8]
 LDCM0259  AC14 HCT 116 C365(1.19); C410(0.42); C412(0.42); C474(0.66)  LDD0576  [8]
 LDCM0260  AC140 HCT 116 C365(1.03); C474(0.98); C479(0.98); C607(0.96)  LDD0577  [8]
 LDCM0261  AC141 HCT 116 C365(0.94); C474(0.98); C479(0.98); C607(0.99)  LDD0578  [8]
 LDCM0262  AC142 HCT 116 C365(0.88); C474(1.01); C479(1.01); C607(1.01)  LDD0579  [8]
 LDCM0263  AC143 HCT 116 C410(1.32); C412(1.32); C474(0.97); C479(0.97)  LDD0580  [8]
 LDCM0264  AC144 HCT 116 C410(0.17); C412(0.17); C474(0.67); C479(0.67)  LDD0581  [8]
 LDCM0265  AC145 HCT 116 C410(0.37); C412(0.37); C607(1.06); C474(1.08)  LDD0582  [8]
 LDCM0266  AC146 HCT 116 C410(0.27); C412(0.27); C474(0.72); C479(0.72)  LDD0583  [8]
 LDCM0267  AC147 HCT 116 C410(0.24); C412(0.24); C474(0.75); C479(0.75)  LDD0584  [8]
 LDCM0268  AC148 HCT 116 C410(0.19); C412(0.19); C474(0.67); C479(0.67)  LDD0585  [8]
 LDCM0269  AC149 HCT 116 C410(0.19); C412(0.19); C474(0.64); C479(0.64)  LDD0586  [8]
 LDCM0270  AC15 HCT 116 C410(0.55); C412(0.55); C474(0.70); C479(0.70)  LDD0587  [8]
 LDCM0271  AC150 HCT 116 C410(0.52); C412(0.52); C474(0.83); C479(0.83)  LDD0588  [8]
 LDCM0272  AC151 HCT 116 C410(0.47); C412(0.47); C474(0.84); C479(0.84)  LDD0589  [8]
 LDCM0273  AC152 HCT 116 C410(0.24); C412(0.24); C474(0.65); C479(0.65)  LDD0590  [8]
 LDCM0274  AC153 HCT 116 C410(0.18); C412(0.18); C474(0.73); C479(0.73)  LDD0591  [8]
 LDCM0621  AC154 HCT 116 C410(0.27); C412(0.27); C474(0.88); C479(0.88)  LDD2158  [8]
 LDCM0622  AC155 HCT 116 C410(0.27); C412(0.27); C474(0.89); C479(0.89)  LDD2159  [8]
 LDCM0623  AC156 HCT 116 C410(0.45); C412(0.45); C474(0.90); C479(0.90)  LDD2160  [8]
 LDCM0624  AC157 HCT 116 C410(0.37); C412(0.37); C474(1.12); C479(1.12)  LDD2161  [8]
 LDCM0276  AC17 HCT 116 C474(0.94); C479(0.94); C607(1.06)  LDD0593  [8]
 LDCM0277  AC18 HCT 116 C474(0.75); C479(0.77); C607(1.08)  LDD0594  [8]
 LDCM0278  AC19 HCT 116 C474(0.85); C479(0.87); C607(1.15)  LDD0595  [8]
 LDCM0279  AC2 HCT 116 C474(0.74); C479(0.74); C365(0.91); C607(1.09)  LDD0596  [8]
 LDCM0280  AC20 HCT 116 C474(0.98); C479(1.04); C607(1.10)  LDD0597  [8]
 LDCM0281  AC21 HCT 116 C474(0.89); C479(0.93); C607(1.00)  LDD0598  [8]
 LDCM0282  AC22 HCT 116 C607(1.00); C474(1.02); C479(1.04)  LDD0599  [8]
 LDCM0283  AC23 HCT 116 C607(0.98); C474(1.00); C479(1.03)  LDD0600  [8]
 LDCM0284  AC24 HCT 116 C474(1.11); C479(1.15); C607(1.20)  LDD0601  [8]
 LDCM0285  AC25 HCT 116 C474(0.72); C479(0.72); C365(0.84); C607(1.00)  LDD0602  [8]
 LDCM0286  AC26 HCT 116 C474(0.55); C479(0.56); C365(0.73); C607(1.04)  LDD0603  [8]
 LDCM0287  AC27 HCT 116 C474(0.55); C479(0.56); C365(0.75); C607(1.21)  LDD0604  [8]
 LDCM0288  AC28 HCT 116 C474(0.59); C479(0.60); C365(0.85); C607(1.01)  LDD0605  [8]
 LDCM0289  AC29 HCT 116 C474(0.56); C479(0.58); C365(0.69); C607(1.14)  LDD0606  [8]
 LDCM0290  AC3 HCT 116 C474(0.79); C479(0.79); C365(0.98); C607(1.17)  LDD0607  [8]
 LDCM0291  AC30 HCT 116 C474(0.53); C479(0.53); C365(0.69); C607(1.28)  LDD0608  [8]
 LDCM0292  AC31 HCT 116 C474(0.54); C479(0.54); C365(0.75); C607(1.29)  LDD0609  [8]
 LDCM0293  AC32 HCT 116 C479(0.45); C474(0.46); C365(0.64); C607(1.41)  LDD0610  [8]
 LDCM0294  AC33 HCT 116 C474(0.50); C479(0.50); C365(0.75); C607(1.38)  LDD0611  [8]
 LDCM0295  AC34 HCT 116 C479(0.53); C474(0.53); C365(0.75); C607(1.30)  LDD0612  [8]
 LDCM0296  AC35 HCT 116 C607(1.08); C365(1.30); C474(1.36); C479(1.38)  LDD0613  [8]
 LDCM0297  AC36 HCT 116 C474(1.03); C365(1.03); C479(1.13); C607(1.24)  LDD0614  [8]
 LDCM0298  AC37 HCT 116 C410(0.73); C412(0.73); C607(0.97); C474(0.97)  LDD0615  [8]
 LDCM0299  AC38 HCT 116 C410(0.94); C412(0.94); C365(1.01); C474(1.12)  LDD0616  [8]
 LDCM0300  AC39 HCT 116 C474(1.01); C479(1.03); C365(1.07); C410(1.10)  LDD0617  [8]
 LDCM0301  AC4 HCT 116 C474(0.78); C479(0.78); C365(1.22); C607(1.26)  LDD0618  [8]
 LDCM0302  AC40 HCT 116 C410(0.74); C412(0.74); C365(0.91); C474(0.94)  LDD0619  [8]
 LDCM0303  AC41 HCT 116 C410(0.74); C412(0.74); C365(0.94); C474(1.02)  LDD0620  [8]
 LDCM0304  AC42 HCT 116 C365(0.94); C479(0.99); C474(1.00); C410(1.04)  LDD0621  [8]
 LDCM0305  AC43 HCT 116 C410(0.65); C412(0.65); C365(0.79); C474(0.84)  LDD0622  [8]
 LDCM0306  AC44 HCT 116 C365(0.85); C410(0.87); C412(0.87); C474(1.00)  LDD0623  [8]
 LDCM0307  AC45 HCT 116 C410(0.56); C412(0.56); C365(0.77); C474(0.87)  LDD0624  [8]
 LDCM0308  AC46 HCT 116 C474(0.88); C479(0.92)  LDD0625  [8]
 LDCM0309  AC47 HCT 116 C474(0.87); C479(0.91)  LDD0626  [8]
 LDCM0310  AC48 HCT 116 C474(0.68); C479(0.71)  LDD0627  [8]
 LDCM0311  AC49 HCT 116 C479(0.73); C474(0.74)  LDD0628  [8]
 LDCM0312  AC5 HCT 116 C474(0.75); C479(0.75); C365(1.20); C607(1.29)  LDD0629  [8]
 LDCM0313  AC50 HCT 116 C479(0.72); C474(0.72)  LDD0630  [8]
 LDCM0314  AC51 HCT 116 C474(0.95); C479(1.02)  LDD0631  [8]
 LDCM0315  AC52 HCT 116 C474(0.98); C479(1.03)  LDD0632  [8]
 LDCM0316  AC53 HCT 116 C474(0.84); C479(0.88)  LDD0633  [8]
 LDCM0317  AC54 HCT 116 C474(0.85); C479(0.93)  LDD0634  [8]
 LDCM0318  AC55 HCT 116 C474(0.75); C479(0.77)  LDD0635  [8]
 LDCM0319  AC56 HCT 116 C474(0.72); C479(0.74)  LDD0636  [8]
 LDCM0320  AC57 HCT 116 C365(0.37); C474(0.64); C479(0.64); C607(1.55)  LDD0637  [8]
 LDCM0321  AC58 HCT 116 C365(0.33); C474(0.58); C479(0.58); C607(1.89)  LDD0638  [8]
 LDCM0322  AC59 HCT 116 C365(0.41); C474(0.56); C479(0.56); C607(1.89)  LDD0639  [8]
 LDCM0323  AC6 HCT 116 C410(0.57); C412(0.57); C474(0.65); C479(0.65)  LDD0640  [8]
 LDCM0324  AC60 HCT 116 C365(0.32); C474(0.51); C479(0.51); C607(1.91)  LDD0641  [8]
 LDCM0325  AC61 HCT 116 C365(0.28); C474(0.47); C479(0.47); C607(1.56)  LDD0642  [8]
 LDCM0326  AC62 HCT 116 C365(0.37); C474(0.50); C479(0.50); C607(1.89)  LDD0643  [8]
 LDCM0327  AC63 HCT 116 C365(0.35); C474(0.52); C479(0.52); C607(1.68)  LDD0644  [8]
 LDCM0328  AC64 HCT 116 C365(0.34); C474(0.54); C479(0.54); C607(2.27)  LDD0645  [8]
 LDCM0329  AC65 HCT 116 C365(0.38); C474(0.51); C479(0.51); C607(1.75)  LDD0646  [8]
 LDCM0330  AC66 HCT 116 C365(0.38); C474(0.58); C479(0.58); C607(1.54)  LDD0647  [8]
 LDCM0331  AC67 HCT 116 C365(0.28); C474(0.45); C479(0.45); C607(1.67)  LDD0648  [8]
 LDCM0332  AC68 HCT 116 C410(0.51); C412(0.51); C474(0.84); C479(0.84)  LDD0649  [8]
 LDCM0333  AC69 HCT 116 C410(0.50); C412(0.50); C474(0.83); C479(0.83)  LDD0650  [8]
 LDCM0334  AC7 HCT 116 C410(0.68); C412(0.68); C474(0.74); C479(0.74)  LDD0651  [8]
 LDCM0335  AC70 HCT 116 C410(0.36); C412(0.36); C474(0.74); C479(0.74)  LDD0652  [8]
 LDCM0336  AC71 HCT 116 C410(0.58); C412(0.58); C607(1.00); C474(1.07)  LDD0653  [8]
 LDCM0337  AC72 HCT 116 C410(0.62); C412(0.62); C474(0.80); C479(0.80)  LDD0654  [8]
 LDCM0338  AC73 HCT 116 C410(0.38); C412(0.38); C474(0.68); C479(0.68)  LDD0655  [8]
 LDCM0339  AC74 HCT 116 C410(0.39); C412(0.39); C474(0.84); C479(0.84)  LDD0656  [8]
 LDCM0340  AC75 HCT 116 C410(0.44); C412(0.44); C474(0.78); C479(0.78)  LDD0657  [8]
 LDCM0341  AC76 HCT 116 C410(0.44); C412(0.44); C474(0.90); C479(0.90)  LDD0658  [8]
 LDCM0342  AC77 HCT 116 C410(0.41); C412(0.41); C474(0.74); C479(0.74)  LDD0659  [8]
 LDCM0343  AC78 HCT 116 C410(0.42); C412(0.42); C474(0.74); C479(0.74)  LDD0660  [8]
 LDCM0344  AC79 HCT 116 C410(0.73); C412(0.73); C474(0.95); C479(0.95)  LDD0661  [8]
 LDCM0345  AC8 HCT 116 C410(0.68); C412(0.68); C474(0.74); C479(0.74)  LDD0662  [8]
 LDCM0346  AC80 HCT 116 C410(0.49); C412(0.49); C474(0.93); C479(0.93)  LDD0663  [8]
 LDCM0347  AC81 HCT 116 C410(0.62); C412(0.62); C607(0.88); C474(1.07)  LDD0664  [8]
 LDCM0348  AC82 HCT 116 C410(0.48); C412(0.48); C474(0.89); C479(0.89)  LDD0665  [8]
 LDCM0349  AC83 HCT 116 C479(0.59); C474(0.65); C365(0.74); C607(1.45)  LDD0666  [8]
 LDCM0350  AC84 HCT 116 C479(0.70); C365(0.72); C474(0.77); C607(1.05)  LDD0667  [8]
 LDCM0351  AC85 HCT 116 C479(0.67); C365(0.70); C474(0.70); C607(0.95)  LDD0668  [8]
 LDCM0352  AC86 HCT 116 C365(0.74); C479(0.86); C474(0.90); C607(1.10)  LDD0669  [8]
 LDCM0353  AC87 HCT 116 C607(0.90); C479(0.91); C474(0.96); C365(1.12)  LDD0670  [8]
 LDCM0354  AC88 HCT 116 C479(0.98); C474(0.99); C607(1.03); C365(1.21)  LDD0671  [8]
 LDCM0355  AC89 HCT 116 C479(0.71); C474(0.75); C365(0.82); C607(1.13)  LDD0672  [8]
 LDCM0357  AC90 HCT 116 C365(0.95); C607(1.01); C479(1.26); C474(1.32)  LDD0674  [8]
 LDCM0358  AC91 HCT 116 C479(0.67); C474(0.71); C365(0.74); C607(1.29)  LDD0675  [8]
 LDCM0359  AC92 HCT 116 C479(0.69); C365(0.70); C474(0.72); C607(1.33)  LDD0676  [8]
 LDCM0360  AC93 HCT 116 C365(0.76); C479(0.86); C474(0.91); C607(0.98)  LDD0677  [8]
 LDCM0361  AC94 HCT 116 C365(0.69); C607(0.86); C479(0.90); C474(0.96)  LDD0678  [8]
 LDCM0362  AC95 HCT 116 C479(0.65); C474(0.73); C607(0.89); C365(0.98)  LDD0679  [8]
 LDCM0363  AC96 HCT 116 C365(0.79); C479(0.87); C474(0.90); C607(1.16)  LDD0680  [8]
 LDCM0364  AC97 HCT 116 C479(0.66); C474(0.71); C365(0.73); C607(1.05)  LDD0681  [8]
 LDCM0365  AC98 HCT 116 C479(0.50); C474(0.51); C365(0.77); C607(0.95)  LDD0682  [8]
 LDCM0366  AC99 HCT 116 C474(0.75); C479(0.76); C607(0.77); C365(0.80)  LDD0683  [8]
 LDCM0248  AKOS034007472 HCT 116 C365(1.21); C410(0.78); C412(0.78); C474(0.89)  LDD0565  [8]
 LDCM0356  AKOS034007680 HCT 116 C410(0.62); C412(0.62); C474(0.73); C479(0.73)  LDD0673  [8]
 LDCM0275  AKOS034007705 HCT 116 C410(0.32); C412(0.32); C474(0.54); C479(0.54)  LDD0592  [8]
 LDCM0156  Aniline NCI-H1299 11.33  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C607(0.97)  LDD0078  [8]
 LDCM0108  Chloroacetamide HeLa H160(0.00); C517(0.00); C607(0.00)  LDD0222  [16]
 LDCM0367  CL1 HCT 116 C412(0.86); C365(0.94); C410(1.02); C474(1.05)  LDD0684  [8]
 LDCM0368  CL10 HCT 116 C365(0.57); C474(0.58); C479(0.58); C412(0.58)  LDD0685  [8]
 LDCM0369  CL100 HCT 116 C474(0.66); C479(0.66); C365(1.03); C607(1.08)  LDD0686  [8]
 LDCM0370  CL101 HCT 116 C410(0.58); C412(0.58); C474(0.68); C479(0.68)  LDD0687  [8]
 LDCM0371  CL102 HCT 116 C410(0.69); C412(0.69); C474(0.72); C479(0.72)  LDD0688  [8]
 LDCM0372  CL103 HCT 116 C410(0.63); C412(0.63); C474(0.96); C479(0.96)  LDD0689  [8]
 LDCM0373  CL104 HCT 116 C410(0.71); C412(0.71); C474(0.76); C479(0.76)  LDD0690  [8]
 LDCM0374  CL105 HCT 116 C474(0.79); C479(0.84); C607(1.03)  LDD0691  [8]
 LDCM0375  CL106 HCT 116 C474(0.69); C479(0.76); C607(1.28)  LDD0692  [8]
 LDCM0376  CL107 HCT 116 C474(0.76); C479(0.79); C607(1.12)  LDD0693  [8]
 LDCM0377  CL108 HCT 116 C474(0.72); C479(0.78); C607(1.33)  LDD0694  [8]
 LDCM0378  CL109 HCT 116 C474(0.77); C479(0.79); C607(1.12)  LDD0695  [8]
 LDCM0379  CL11 HCT 116 C410(0.44); C365(0.55); C412(0.59); C474(0.65)  LDD0696  [8]
 LDCM0380  CL110 HCT 116 C474(0.80); C479(0.84); C607(1.07)  LDD0697  [8]
 LDCM0381  CL111 HCT 116 C474(0.81); C479(0.83); C607(1.07)  LDD0698  [8]
 LDCM0382  CL112 HCT 116 C365(0.80); C474(0.85); C479(0.87); C607(1.02)  LDD0699  [8]
 LDCM0383  CL113 HCT 116 C474(0.51); C479(0.52); C365(0.67); C607(1.12)  LDD0700  [8]
 LDCM0384  CL114 HCT 116 C365(0.57); C479(0.61); C474(0.61); C607(1.15)  LDD0701  [8]
 LDCM0385  CL115 HCT 116 C474(0.55); C479(0.55); C365(0.69); C607(1.12)  LDD0702  [8]
 LDCM0386  CL116 HCT 116 C479(0.56); C474(0.56); C365(0.69); C607(1.34)  LDD0703  [8]
 LDCM0387  CL117 HCT 116 C410(0.61); C412(0.61); C474(0.68); C479(0.70)  LDD0704  [8]
 LDCM0388  CL118 HCT 116 C410(0.60); C412(0.60); C365(0.88); C474(1.01)  LDD0705  [8]
 LDCM0389  CL119 HCT 116 C410(0.59); C412(0.59); C365(0.85); C474(0.89)  LDD0706  [8]
 LDCM0390  CL12 HCT 116 C365(0.54); C474(0.57); C479(0.57); C410(0.80)  LDD0707  [8]
 LDCM0391  CL120 HCT 116 C410(0.88); C412(0.88); C365(1.01); C474(1.07)  LDD0708  [8]
 LDCM0392  CL121 HCT 116 C474(1.18); C479(1.39)  LDD0709  [8]
 LDCM0393  CL122 HCT 116 C474(0.76); C479(0.78)  LDD0710  [8]
 LDCM0394  CL123 HCT 116 C474(0.78); C479(0.83)  LDD0711  [8]
 LDCM0395  CL124 HCT 116 C474(0.73); C479(0.77)  LDD0712  [8]
 LDCM0396  CL125 HCT 116 C365(0.69); C474(0.69); C479(0.69); C607(1.15)  LDD0713  [8]
 LDCM0397  CL126 HCT 116 C365(0.52); C474(0.65); C479(0.65); C607(1.26)  LDD0714  [8]
 LDCM0398  CL127 HCT 116 C365(0.53); C474(0.57); C479(0.57); C607(1.22)  LDD0715  [8]
 LDCM0399  CL128 HCT 116 C365(0.41); C474(0.63); C479(0.63); C607(1.72)  LDD0716  [8]
 LDCM0400  CL13 HCT 116 C412(0.49); C365(0.57); C474(0.59); C479(0.59)  LDD0717  [8]
 LDCM0401  CL14 HCT 116 C474(0.69); C479(0.69); C365(0.77); C412(0.84)  LDD0718  [8]
 LDCM0402  CL15 HCT 116 C410(0.54); C365(0.55); C474(0.55); C479(0.55)  LDD0719  [8]
 LDCM0403  CL16 HCT 116 C410(0.63); C412(0.63); C474(0.68); C479(0.68)  LDD0720  [8]
 LDCM0404  CL17 HCT 116 C410(0.56); C412(0.56); C474(0.59); C479(0.59)  LDD0721  [8]
 LDCM0405  CL18 HCT 116 C410(0.28); C412(0.28); C474(0.45); C479(0.45)  LDD0722  [8]
 LDCM0406  CL19 HCT 116 C410(0.48); C412(0.48); C474(0.62); C479(0.62)  LDD0723  [8]
 LDCM0407  CL2 HCT 116 C410(0.89); C474(0.90); C479(0.90); C412(1.01)  LDD0724  [8]
 LDCM0408  CL20 HCT 116 C410(0.48); C412(0.48); C474(0.56); C479(0.56)  LDD0725  [8]
 LDCM0409  CL21 HCT 116 C410(0.37); C412(0.37); C474(0.56); C479(0.56)  LDD0726  [8]
 LDCM0410  CL22 HCT 116 C410(0.39); C412(0.39); C474(0.56); C479(0.56)  LDD0727  [8]
 LDCM0411  CL23 HCT 116 C410(0.55); C412(0.55); C365(0.68); C474(0.74)  LDD0728  [8]
 LDCM0412  CL24 HCT 116 C410(0.38); C412(0.38); C474(0.52); C479(0.52)  LDD0729  [8]
 LDCM0413  CL25 HCT 116 C365(0.60); C410(0.44); C412(0.44); C474(0.55)  LDD0730  [8]
 LDCM0414  CL26 HCT 116 C365(0.66); C410(0.56); C412(0.56); C474(0.57)  LDD0731  [8]
 LDCM0415  CL27 HCT 116 C365(0.71); C410(0.48); C412(0.48); C474(0.63)  LDD0732  [8]
 LDCM0416  CL28 HCT 116 C365(0.58); C410(0.53); C412(0.53); C474(0.51)  LDD0733  [8]
 LDCM0417  CL29 HCT 116 C365(0.65); C410(0.47); C412(0.47); C474(0.53)  LDD0734  [8]
 LDCM0418  CL3 HCT 116 C365(0.83); C410(0.91); C412(0.89); C474(0.78)  LDD0735  [8]
 LDCM0419  CL30 HCT 116 C365(0.70); C410(0.56); C412(0.56); C474(0.73)  LDD0736  [8]
 LDCM0420  CL31 HCT 116 C365(0.75); C410(0.85); C412(0.85); C474(0.75)  LDD0737  [8]
 LDCM0421  CL32 HCT 116 C365(0.64); C410(0.32); C412(0.32); C474(0.53)  LDD0738  [8]
 LDCM0422  CL33 HCT 116 C365(0.56); C410(0.37); C412(0.37); C474(0.59)  LDD0739  [8]
 LDCM0423  CL34 HCT 116 C365(0.68); C410(0.51); C412(0.51); C474(0.57)  LDD0740  [8]
 LDCM0424  CL35 HCT 116 C365(0.65); C410(0.48); C412(0.48); C474(0.58)  LDD0741  [8]
 LDCM0425  CL36 HCT 116 C365(0.70); C410(0.54); C412(0.54); C474(0.66)  LDD0742  [8]
 LDCM0426  CL37 HCT 116 C365(0.72); C410(0.41); C412(0.41); C474(0.62)  LDD0743  [8]
 LDCM0428  CL39 HCT 116 C365(0.77); C410(0.47); C412(0.47); C474(0.73)  LDD0745  [8]
 LDCM0429  CL4 HCT 116 C365(0.84); C410(0.87); C412(0.65); C474(0.77)  LDD0746  [8]
 LDCM0430  CL40 HCT 116 C365(0.72); C410(0.53); C412(0.53); C474(0.72)  LDD0747  [8]
 LDCM0431  CL41 HCT 116 C365(0.77); C410(0.52); C412(0.52); C474(0.67)  LDD0748  [8]
 LDCM0432  CL42 HCT 116 C365(0.66); C410(0.43); C412(0.43); C474(0.64)  LDD0749  [8]
 LDCM0433  CL43 HCT 116 C365(0.70); C410(0.42); C412(0.42); C474(0.56)  LDD0750  [8]
 LDCM0434  CL44 HCT 116 C365(0.68); C410(0.38); C412(0.38); C474(0.56)  LDD0751  [8]
 LDCM0435  CL45 HCT 116 C365(0.68); C410(0.41); C412(0.41); C474(0.55)  LDD0752  [8]
 LDCM0436  CL46 HCT 116 C365(0.99); C474(1.58); C479(1.58); C607(0.99)  LDD0753  [8]
 LDCM0437  CL47 HCT 116 C365(0.74); C474(1.34); C479(1.34); C607(0.98)  LDD0754  [8]
 LDCM0438  CL48 HCT 116 C365(0.83); C474(1.54); C479(1.54); C607(0.96)  LDD0755  [8]
 LDCM0439  CL49 HCT 116 C365(1.12); C474(1.23); C479(1.23); C607(0.90)  LDD0756  [8]
 LDCM0440  CL5 HCT 116 C365(0.80); C410(0.77); C412(0.81); C474(0.77)  LDD0757  [8]
 LDCM0441  CL50 HCT 116 C365(1.15); C474(1.40); C479(1.40); C607(0.81)  LDD0758  [8]
 LDCM0442  CL51 HCT 116 C365(0.95); C474(1.45); C479(1.45); C607(0.91)  LDD0759  [8]
 LDCM0443  CL52 HCT 116 C365(0.92); C474(1.29); C479(1.29); C607(1.10)  LDD0760  [8]
 LDCM0444  CL53 HCT 116 C365(0.74); C474(1.36); C479(1.36); C607(1.02)  LDD0761  [8]
 LDCM0445  CL54 HCT 116 C365(0.79); C474(1.44); C479(1.44); C607(0.97)  LDD0762  [8]
 LDCM0446  CL55 HCT 116 C365(0.84); C474(1.65); C479(1.65); C607(0.94)  LDD0763  [8]
 LDCM0447  CL56 HCT 116 C365(0.83); C474(1.23); C479(1.23); C607(1.11)  LDD0764  [8]
 LDCM0448  CL57 HCT 116 C365(0.88); C474(1.36); C479(1.36); C607(1.05)  LDD0765  [8]
 LDCM0449  CL58 HCT 116 C365(0.97); C474(1.31); C479(1.31); C607(1.01)  LDD0766  [8]
 LDCM0450  CL59 HCT 116 C365(0.91); C474(1.19); C479(1.19); C607(1.01)  LDD0767  [8]
 LDCM0451  CL6 HCT 116 C365(0.56); C410(0.60); C412(0.64); C474(0.54)  LDD0768  [8]
 LDCM0452  CL60 HCT 116 C365(0.92); C474(1.22); C479(1.22); C607(1.00)  LDD0769  [8]
 LDCM0453  CL61 HCT 116 C365(0.99); C410(0.95); C412(0.95); C474(0.97)  LDD0770  [8]
 LDCM0454  CL62 HCT 116 C365(0.94); C410(0.93); C412(0.93); C474(0.89)  LDD0771  [8]
 LDCM0455  CL63 HCT 116 C365(0.82); C410(0.70); C412(0.70); C474(0.97)  LDD0772  [8]
 LDCM0456  CL64 HCT 116 C365(0.84); C410(0.67); C412(0.67); C474(0.97)  LDD0773  [8]
 LDCM0457  CL65 HCT 116 C365(0.95); C410(0.79); C412(0.79); C474(0.95)  LDD0774  [8]
 LDCM0458  CL66 HCT 116 C365(0.73); C410(0.54); C412(0.54); C474(0.94)  LDD0775  [8]
 LDCM0459  CL67 HCT 116 C365(0.75); C410(0.66); C412(0.66); C474(0.95)  LDD0776  [8]
 LDCM0460  CL68 HCT 116 C365(0.62); C410(0.53); C412(0.53); C474(0.90)  LDD0777  [8]
 LDCM0461  CL69 HCT 116 C365(0.65); C410(0.41); C412(0.41); C474(0.76)  LDD0778  [8]
 LDCM0462  CL7 HCT 116 C365(0.64); C410(0.74); C412(0.75); C474(0.63)  LDD0779  [8]
 LDCM0463  CL70 HCT 116 C365(0.76); C410(0.54); C412(0.54); C474(0.76)  LDD0780  [8]
 LDCM0464  CL71 HCT 116 C365(0.88); C410(0.73); C412(0.73); C474(0.93)  LDD0781  [8]
 LDCM0465  CL72 HCT 116 C365(1.11); C410(0.85); C412(0.85); C474(0.88)  LDD0782  [8]
 LDCM0466  CL73 HCT 116 C365(0.81); C410(0.61); C412(0.61); C474(1.00)  LDD0783  [8]
 LDCM0467  CL74 HCT 116 C365(0.77); C410(0.64); C412(0.64); C474(0.95)  LDD0784  [8]
 LDCM0469  CL76 HCT 116 C365(0.81); C410(0.76); C412(0.81); C474(0.66)  LDD0786  [8]
 LDCM0470  CL77 HCT 116 C365(0.91); C410(0.83); C412(0.95); C474(0.98)  LDD0787  [8]
 LDCM0471  CL78 HCT 116 C365(0.82); C410(0.92); C412(0.88); C474(0.93)  LDD0788  [8]
 LDCM0472  CL79 HCT 116 C365(0.86); C410(0.76); C412(0.82); C474(0.72)  LDD0789  [8]
 LDCM0473  CL8 HCT 116 C365(0.59); C410(0.62); C412(0.67); C474(0.70)  LDD0790  [8]
 LDCM0474  CL80 HCT 116 C365(0.77); C410(0.74); C412(0.71); C474(0.69)  LDD0791  [8]
 LDCM0475  CL81 HCT 116 C365(1.01); C410(0.84); C412(0.92); C474(0.85)  LDD0792  [8]
 LDCM0476  CL82 HCT 116 C365(0.90); C410(0.86); C412(0.86); C474(0.66)  LDD0793  [8]
 LDCM0477  CL83 HCT 116 C365(0.86); C410(0.82); C412(0.91); C474(0.69)  LDD0794  [8]
 LDCM0478  CL84 HCT 116 C365(0.78); C410(0.65); C412(0.65); C474(0.65)  LDD0795  [8]
 LDCM0479  CL85 HCT 116 C365(0.92); C410(0.88); C412(0.88); C474(0.77)  LDD0796  [8]
 LDCM0480  CL86 HCT 116 C365(0.91); C410(1.11); C412(1.12); C474(0.94)  LDD0797  [8]
 LDCM0481  CL87 HCT 116 C365(1.11); C410(0.93); C412(1.00); C474(0.75)  LDD0798  [8]
 LDCM0482  CL88 HCT 116 C365(1.03); C410(0.70); C412(0.71); C474(0.74)  LDD0799  [8]
 LDCM0483  CL89 HCT 116 C365(0.73); C410(0.81); C412(0.82); C474(0.77)  LDD0800  [8]
 LDCM0484  CL9 HCT 116 C365(0.81); C410(0.86); C412(0.76); C474(0.68)  LDD0801  [8]
 LDCM0485  CL90 HCT 116 C365(0.96); C410(1.07); C412(1.28); C474(1.12)  LDD0802  [8]
 LDCM0486  CL91 HCT 116 C365(0.97); C474(0.81); C479(0.81); C607(1.18)  LDD0803  [8]
 LDCM0487  CL92 HCT 116 C365(1.03); C474(0.86); C479(0.86); C607(1.09)  LDD0804  [8]
 LDCM0488  CL93 HCT 116 C365(1.26); C474(0.79); C479(0.79); C607(0.98)  LDD0805  [8]
 LDCM0489  CL94 HCT 116 C365(1.08); C474(0.70); C479(0.70); C607(0.90)  LDD0806  [8]
 LDCM0490  CL95 HCT 116 C365(1.05); C474(0.67); C479(0.67); C607(1.16)  LDD0807  [8]
 LDCM0491  CL96 HCT 116 C365(0.95); C474(0.79); C479(0.79); C607(1.28)  LDD0808  [8]
 LDCM0492  CL97 HCT 116 C365(0.87); C474(0.72); C479(0.72); C607(1.25)  LDD0809  [8]
 LDCM0493  CL98 HCT 116 C365(0.92); C474(0.68); C479(0.68); C607(1.24)  LDD0810  [8]
 LDCM0494  CL99 HCT 116 C365(1.05); C474(0.70); C479(0.70); C607(1.32)  LDD0811  [8]
 LDCM0495  E2913 HEK-293T C294(1.05); C517(1.01); C365(0.93); C410(1.24)  LDD1698  [20]
 LDCM0468  Fragment33 HCT 116 C365(0.83); C410(0.71); C412(0.71); C474(0.95)  LDD0785  [8]
 LDCM0427  Fragment51 HCT 116 C365(0.67); C410(0.44); C412(0.44); C474(0.65)  LDD0744  [8]
 LDCM0116  HHS-0101 DM93 Y76(1.27)  LDD0264  [6]
 LDCM0117  HHS-0201 DM93 Y76(1.04)  LDD0265  [6]
 LDCM0118  HHS-0301 DM93 Y76(0.99)  LDD0266  [6]
 LDCM0119  HHS-0401 DM93 Y76(1.04)  LDD0267  [6]
 LDCM0120  HHS-0701 DM93 Y76(1.73)  LDD0268  [6]
 LDCM0022  KB02 HEK-293T C517(1.03); C365(1.04); C412(1.27); C294(0.94)  LDD1492  [20]
 LDCM0023  KB03 HEK-293T C517(1.00); C365(1.07); C412(0.98); C294(0.95)  LDD1497  [20]
 LDCM0024  KB05 G361 C294(2.70)  LDD3311  [21]
 LDCM0109  NEM HeLa N.A.  LDD0223  [16]

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
3 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
4 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
5 An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. Anal Chem. 2021 Jul 27;93(29):10334-10342. doi: 10.1021/acs.analchem.1c01935. Epub 2021 Jul 12.
6 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
7 Global targeting of functional tyrosines using sulfur-triazole exchange chemistry. Nat Chem Biol. 2020 Feb;16(2):150-159. doi: 10.1038/s41589-019-0404-5. Epub 2019 Nov 25.
8 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
9 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
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Mass spectrometry data entry: PXD028853
11 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
12 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
13 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
14 Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20.
Mass spectrometry data entry: PXD022279
15 Site-Specific Activity-Based Protein Profiling Using Phosphonate Handles. Mol Cell Proteomics. 2023 Jan;22(1):100455. doi: 10.1016/j.mcpro.2022.100455. Epub 2022 Nov 24.
Mass spectrometry data entry: PXD036569
16 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
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18 Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8551-6. doi: 10.1002/anie.201300683. Epub 2013 Jun 10.
19 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.
20 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
21 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840