Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name Kambe_26  Probe Info 
Probe concentration 10 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name Kambe_cp3  Competitor Info 
Competitor Concentration 10 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Prostate
Disease Model Prostate carcinoma [ICD-11:2C82]
Model Name Human prostate carcinoma cells (PC-3)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 6 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03223  Small ribosomal subunit protein uS3 (RPS3) 20.0
 LDTP03515  Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3) 16.9
 LDTP02385  Leukotriene A-4 hydrolase (LTA4H) 12.5
 LDTP06384  Ribosomal protein S6 kinase alpha-1 (RPS6KA1) 8.0
 LDTP04471  Ribosomal protein S6 kinase alpha-3 (RPS6KA3) 6.2
 LDTP01766  L-lactate dehydrogenase A chain (LDHA) 3.3
Other
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01316  Breast cancer anti-estrogen resistance protein 3 (BCAR3) 12.4

References

1 Mapping the protein interaction landscape for fully functionalized small-molecule probes in human cells. J Am Chem Soc. 2014 Jul 30;136(30):10777-82. doi: 10.1021/ja505517t. Epub 2014 Jul 21.