Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C156 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02175 | Epoxide hydrolase 1 (EPHX1) | 28.1 | ||||
| LDTP08728 | Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) | 20.1 | ||||
| LDTP05758 | S-methyl-5'-thioadenosine phosphorylase (MTAP) | 19.3 | ||||
| LDTP00697 | Cytochrome b5 type B (CYB5B) | 10.4 | ||||
| LDTP12020 | Histone-lysine N-methyltransferase SMYD3 (SMYD3) | 9.4 | ||||
| LDTP00907 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) | 9.4 | ||||
| LDTP02359 | Heme oxygenase 1 (HMOX1) | 9.3 | ||||
| LDTP14218 | Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) | 8.8 | ||||
| LDTP11273 | N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) | 8.5 | ||||
| LDTP04285 | Proteasome subunit beta type-2 (PSMB2) | 8.4 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 8.3 | ||||
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 7.9 | ||||
| LDTP09391 | Ceramide kinase (CERK) | 7.2 | ||||
| LDTP09088 | Phospholipase A2 group XV (PLA2G15) | 6.4 | ||||
| LDTP15988 | Probable serine carboxypeptidase CPVL (CPVL) | 6.2 | ||||
| LDTP10188 | FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) | 6.0 | ||||
| LDTP15484 | Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) | 5.9 | ||||
| LDTP06477 | Methylsterol monooxygenase 1 (MSMO1) | 5.8 | ||||
| LDTP07831 | Transmembrane protein with metallophosphoesterase domain (TMPPE) | 5.5 | ||||
| LDTP01562 | Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) | 5.2 | ||||
| LDTP01982 | NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) | 5.1 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 23.4 | ||||
| LDTP10958 | Sigma non-opioid intracellular receptor 1 (SIGMAR1) | 22.9 | ||||
| LDTP08881 | Transmembrane protein 199 (TMEM199) | 16.0 | ||||
| LDTP09547 | Scavenger receptor class B member 1 (SCARB1) | 15.9 | ||||
| LDTP11136 | Sugar transporter SWEET1 (SLC50A1) | 15.0 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 14.9 | ||||
| LDTP06034 | Lysosome membrane protein 2 (SCARB2) | 14.8 | ||||
| LDTP07236 | Protein GPR107 (GPR107) | 12.0 | ||||
| LDTP03277 | ER lumen protein-retaining receptor 1 (KDELR1) | 11.2 | ||||
| LDTP06945 | Sigma intracellular receptor 2 (TMEM97) | 8.3 | ||||
| LDTP04071 | Voltage-dependent anion-selective channel protein 2 (VDAC2) | 7.8 | ||||
| LDTP17641 | Solute carrier family 35 member F2 (SLC35F2) | 7.4 | ||||
| LDTP17106 | Solute carrier family 25 member 35 (SLC25A35) | 7.3 | ||||
| LDTP06365 | Transmembrane emp24 domain-containing protein 2 (TMED2) | 6.4 | ||||
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 6.1 | ||||
| LDTP16813 | Tetraspanin-3 (TSPAN3) | 5.7 | ||||
| LDTP07885 | Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) | 5.5 | ||||
| LDTP11615 | Protein tweety homolog 3 (TTYH3) | 5.3 | ||||
| LDTP11406 | Transmembrane protein 59 (TMEM59) | 5.3 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP03678 | ER lumen protein-retaining receptor 2 (KDELR2) | 28.1 | ||||
| LDTP12565 | Mitochondrial import receptor subunit TOM22 homolog (TOMM22) | 12.1 | ||||
| LDTP16099 | p53 and DNA damage-regulated protein 1 (PDRG1) | 10.1 | ||||
| LDTP13828 | Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) | 9.7 | ||||
| LDTP00105 | Protein unc-119 homolog B (UNC119B) | 9.7 | ||||
| LDTP10281 | Cytoplasmic dynein 2 intermediate chain 2 (DYNC2I2) | 9.3 | ||||
| LDTP14486 | Clustered mitochondria protein homolog (CLUH) | 8.2 | ||||
| LDTP04094 | Large proline-rich protein BAG6 (BAG6) | 6.5 | ||||
| LDTP13755 | Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) | 6.1 | ||||
| LDTP06302 | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (ACAP2) | 6.0 | ||||
| LDTP05160 | Nucleobindin-2 (NUCB2) | 5.9 | ||||
| LDTP15067 | Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) | 5.9 | ||||
| LDTP13606 | Mammalian ependymin-related protein 1 (EPDR1) | 5.9 | ||||
| LDTP05375 | Nucleobindin-1 (NUCB1) | 5.8 | ||||
| LDTP05868 | Protein unc-119 homolog A (UNC119) | 5.5 | ||||
| LDTP06097 | Reticulocalbin-2 (RCN2) | 5.3 | ||||
| LDTP14458 | Tetraspanin-6 (TSPAN6) | 5.3 | ||||
| LDTP03520 | Phosphatidylethanolamine-binding protein 1 (PEBP1) | 5.2 | ||||
| LDTP01522 | Reticulon-3 (RTN3) | 5.0 | ||||