Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C167  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 9 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 62.7
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 19.4
 LDTP00907  Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) 10.3
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 9.9
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 8.2
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 8.0
 LDTP08265  N-alpha-acetyltransferase 40 (NAA40) 7.0
 LDTP10286  Corrinoid adenosyltransferase MMAB (MMAB) 6.6
 LDTP10188  FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) 5.4
Transporter and channel
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 10.1
Other
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00105  Protein unc-119 homolog B (UNC119B) 6.2

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587