General Information of Experiment

Probe Name C195  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 13 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 28.8
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 13.3
 LDTP01769  Dihydrofolate reductase (DHFR) 11.1
 LDTP10318  Ubiquitin thioesterase OTUB1 (OTUB1) 7.6
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 7.2
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 7.1
 LDTP07003  Presequence protease, mitochondrial (PITRM1) 6.7
 LDTP10188  FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) 6.5
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 6.4
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 5.7
 LDTP03417  Proteasome subunit beta type-4 (PSMB4) 5.5
 LDTP09043  Lysine-specific histone demethylase 2 (KDM1B) 5.5
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 5.2
Transporter and channel
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP11531  Oxysterol-binding protein-related protein 8 (OSBPL8) 9.8
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 9.1
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 6.1
 LDTP17641  Solute carrier family 35 member F2 (SLC35F2) 5.0
Other
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP13755  Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) 13.7
 LDTP16099  p53 and DNA damage-regulated protein 1 (PDRG1) 10.6
 LDTP15623  Neuferricin (CYB5D2) 5.3
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 5.2

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587