Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C044 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP12363 | Lysophosphatidic acid phosphatase type 6 (ACP6) | 19.7 | ||||
| LDTP10188 | FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) | 12.6 | ||||
| LDTP00907 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) | 12.1 | ||||
| LDTP03842 | Squalene synthase (FDFT1) | 9.1 | ||||
| LDTP10032 | 7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) | 8.8 | ||||
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 7.9 | ||||
| LDTP05758 | S-methyl-5'-thioadenosine phosphorylase (MTAP) | 7.7 | ||||
| LDTP01982 | NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) | 7.6 | ||||
| LDTP00325 | Pirin (PIR) | 7.6 | ||||
| LDTP03540 | Heme oxygenase 2 (HMOX2) | 7.5 | ||||
| LDTP11273 | N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) | 7.4 | ||||
| LDTP09088 | Phospholipase A2 group XV (PLA2G15) | 7.2 | ||||
| LDTP03257 | Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) | 6.9 | ||||
| LDTP13358 | Leucyl-cystinyl aminopeptidase (LNPEP) | 6.7 | ||||
| LDTP04285 | Proteasome subunit beta type-2 (PSMB2) | 6.7 | ||||
| LDTP12020 | Histone-lysine N-methyltransferase SMYD3 (SMYD3) | 6.6 | ||||
| LDTP06333 | Serum paraoxonase/arylesterase 2 (PON2) | 6.6 | ||||
| LDTP00832 | NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) | 6.4 | ||||
| LDTP02175 | Epoxide hydrolase 1 (EPHX1) | 6.1 | ||||
| LDTP01613 | Sphingosine-1-phosphate lyase 1 (SGPL1) | 6.1 | ||||
| LDTP04008 | Endothelin-converting enzyme 1 (ECE1) | 5.9 | ||||
| LDTP02150 | ATP synthase subunit beta, mitochondrial (ATP5F1B) | 5.9 | ||||
| LDTP08017 | Endoplasmic reticulum metallopeptidase 1 (ERMP1) | 5.7 | ||||
| LDTP01787 | Phosphoglycerate kinase 1 (PGK1) | 5.7 | ||||
| LDTP04183 | Lanosterol synthase (LSS) | 5.7 | ||||
| LDTP16032 | Retinoid-inducible serine carboxypeptidase (SCPEP1) | 5.6 | ||||
| LDTP00697 | Cytochrome b5 type B (CYB5B) | 5.5 | ||||
| LDTP01769 | Dihydrofolate reductase (DHFR) | 5.5 | ||||
| LDTP06477 | Methylsterol monooxygenase 1 (MSMO1) | 5.4 | ||||
| LDTP03418 | Proteasome subunit beta type-6 (PSMB6) | 5.1 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 5.1 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02724 | Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) | 30.9 | ||||
| LDTP01969 | Transferrin receptor protein 1 (TFRC) | 27.5 | ||||
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 13.3 | ||||
| LDTP03546 | Translocator protein (TSPO) | 10.3 | ||||
| LDTP17362 | Magnesium transporter NIPA3 (NIPAL1) | 10.0 | ||||
| LDTP04071 | Voltage-dependent anion-selective channel protein 2 (VDAC2) | 9.8 | ||||
| LDTP06945 | Sigma intracellular receptor 2 (TMEM97) | 8.3 | ||||
| LDTP09547 | Scavenger receptor class B member 1 (SCARB1) | 7.6 | ||||
| LDTP14952 | Mpv17-like protein 2 (MPV17L2) | 6.2 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 6.1 | ||||
| LDTP07885 | Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) | 6.0 | ||||
| LDTP03277 | ER lumen protein-retaining receptor 1 (KDELR1) | 6.0 | ||||
| LDTP14511 | ATP synthase subunit g, mitochondrial (ATP5MG) | 5.7 | ||||
| LDTP15948 | Transmembrane protein 126A (TMEM126A) | 5.6 | ||||
| LDTP04592 | Monocarboxylate transporter 1 (SLC16A1) | 5.6 | ||||
| LDTP08881 | Transmembrane protein 199 (TMEM199) | 5.3 | ||||
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 5.0 | ||||
| LDTP11162 | Solute carrier family 25 member 33 (SLC25A33) | 5.0 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP14486 | Clustered mitochondria protein homolog (CLUH) | 7.7 | ||||
| LDTP12565 | Mitochondrial import receptor subunit TOM22 homolog (TOMM22) | 7.2 | ||||
| LDTP03678 | ER lumen protein-retaining receptor 2 (KDELR2) | 7.2 | ||||
| LDTP16192 | Mitochondrial fission process protein 1 (MTFP1) | 6.6 | ||||
| LDTP13902 | Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) | 6.5 | ||||
| LDTP05375 | Nucleobindin-1 (NUCB1) | 6.5 | ||||
| LDTP08689 | Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) | 6.1 | ||||
| LDTP11076 | Apolipoprotein L2 (APOL2) | 5.7 | ||||
| LDTP00105 | Protein unc-119 homolog B (UNC119B) | 5.7 | ||||
| LDTP00281 | Golgi integral membrane protein 4 (GOLIM4) | 5.6 | ||||
| LDTP13828 | Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) | 5.5 | ||||
| LDTP15067 | Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) | 5.1 | ||||