Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C400 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP12253 | Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) | 15.2 | ||||
| LDTP16007 | Lipid droplet-associated hydrolase (LDAH) | 13.7 | ||||
| LDTP15422 | Prostaglandin reductase 3 (PTGR3) | 11.6 | ||||
| LDTP12363 | Lysophosphatidic acid phosphatase type 6 (ACP6) | 9.3 | ||||
| LDTP10188 | FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) | 8.4 | ||||
| LDTP03419 | Proteasome subunit beta type-5 (PSMB5) | 7.3 | ||||
| LDTP06227 | Prostaglandin reductase 1 (PTGR1) | 7.0 | ||||
| LDTP12490 | Sphingosine kinase 2 (SPHK2) | 6.9 | ||||
| LDTP07990 | Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) | 6.1 | ||||
| LDTP12868 | Endoplasmic reticulum aminopeptidase 1 (ERAP1) | 6.0 | ||||
| LDTP00273 | Dynamin-1-like protein (DNM1L) | 5.6 | ||||
| LDTP04542 | Thimet oligopeptidase (THOP1) | 5.2 | ||||
| LDTP08728 | Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) | 5.1 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 16.2 | ||||
| LDTP12383 | Protein GPR108 (GPR108) | 9.7 | ||||
| LDTP13256 | SUN domain-containing protein 2 (SUN2) | 8.3 | ||||
| LDTP10036 | BOS complex subunit NCLN (NCLN) | 7.6 | ||||
| LDTP05900 | Metaxin-1 (MTX1) | 6.0 | ||||
| LDTP01631 | Mitochondrial pyruvate carrier 2 (MPC2) | 5.9 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 5.6 | ||||
| LDTP17362 | Magnesium transporter NIPA3 (NIPAL1) | 5.5 | ||||
| LDTP07236 | Protein GPR107 (GPR107) | 5.5 | ||||
| LDTP09547 | Scavenger receptor class B member 1 (SCARB1) | 5.5 | ||||
| LDTP11162 | Solute carrier family 25 member 33 (SLC25A33) | 5.5 | ||||
| LDTP00592 | Surfeit locus protein 4 (SURF4) | 5.2 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02345 | Retinol-binding protein 1 (RBP1) | 16.2 | ||||
| LDTP14486 | Clustered mitochondria protein homolog (CLUH) | 7.4 | ||||
| LDTP09297 | Large ribosomal subunit protein mL64 (GADD45GIP1) | 6.8 | ||||
| LDTP12565 | Mitochondrial import receptor subunit TOM22 homolog (TOMM22) | 4.9 | ||||
| LDTP05160 | Nucleobindin-2 (NUCB2) | 4.9 | ||||