Details of the Target

General Information of Target

Target ID LDTP11552
Target Name UL16-binding protein 3 (ULBP3)
Gene Name ULBP3
Gene ID 79465
Synonyms
N2DL3; RAET1N; UL16-binding protein 3; ALCAN-gamma; NKG2D ligand 3; N2DL-3; NKG2DL3; Retinoic acid early transcript 1N
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSRSFYVDSLIIKDTSRPAPSLPEPHPGPDFFIPLGMPPPLVMSVSGPGCPSRKSGAFCV
CPLCVTSHLHSSRGSVGAGSGGAGAGVTGAGGSGVAGAAGALPLLKGQFSSAPGDAQFCP
RVNHAHHHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAALGHPQHHAPVCTATTYNV
ADPRRFHCLTMGGSDASQVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLN
LSEKQVKIWFQNRRVKHKKEGKGTQRNSHAGCKCVGSQVHYARSEDEDSLSPASANDDKE
ISPL
Target Bioclass
Other
Family
MHC class I family
Subcellular location
Cell membrane
Function Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
Uniprot ID
Q9BZM4
Ensemble ID
ENST00000367339.7
HGNC ID
HGNC:14895

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
OPA-S-S-alkyne
 Probe Info  		K192(1.43); K148(2.10); K158(2.74)  LDD3494  [1]
DBIA
 Probe Info  		C51(0.85)  LDD0580  [2]
IA-alkyne
 Probe Info  		C67(0.00); C51(0.00)  LDD0165  [3]
IPM
 Probe Info  		N.A.  LDD2156  [4]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [5]
PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C158
 Probe Info  		54.19  LDD1838  [6]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C51(0.90)  LDD0812  [2]
 LDCM0215  AC10 PaTu 8988t C51(0.96)  LDD1094  [2]
 LDCM0216  AC100 HEK-293T C51(1.10)  LDD0814  [2]
 LDCM0217  AC101 HEK-293T C51(1.00)  LDD0815  [2]
 LDCM0218  AC102 HEK-293T C51(0.79)  LDD0816  [2]
 LDCM0219  AC103 HEK-293T C51(0.73)  LDD0817  [2]
 LDCM0220  AC104 HEK-293T C51(0.69)  LDD0818  [2]
 LDCM0221  AC105 HEK-293T C51(1.46)  LDD0819  [2]
 LDCM0222  AC106 HEK-293T C51(1.93)  LDD0820  [2]
 LDCM0223  AC107 HEK-293T C51(0.77)  LDD0821  [2]
 LDCM0224  AC108 HEK-293T C51(1.20)  LDD0822  [2]
 LDCM0225  AC109 HEK-293T C51(1.46)  LDD0823  [2]
 LDCM0226  AC11 PaTu 8988t C51(0.79)  LDD1105  [2]
 LDCM0227  AC110 HEK-293T C51(0.55)  LDD0825  [2]
 LDCM0228  AC111 HEK-293T C51(0.50)  LDD0826  [2]
 LDCM0229  AC112 HEK-293T C51(0.50)  LDD0827  [2]
 LDCM0230  AC113 HEK-293T C51(1.28)  LDD0828  [2]
 LDCM0231  AC114 HEK-293T C51(1.02)  LDD0829  [2]
 LDCM0232  AC115 HEK-293T C51(0.96)  LDD0830  [2]
 LDCM0233  AC116 HEK-293T C51(1.16)  LDD0831  [2]
 LDCM0234  AC117 HEK-293T C51(0.86)  LDD0832  [2]
 LDCM0235  AC118 HEK-293T C51(0.77)  LDD0833  [2]
 LDCM0236  AC119 HEK-293T C51(0.76)  LDD0834  [2]
 LDCM0237  AC12 PaTu 8988t C51(0.66)  LDD1116  [2]
 LDCM0238  AC120 HEK-293T C51(1.10)  LDD0836  [2]
 LDCM0239  AC121 HEK-293T C51(0.72)  LDD0837  [2]
 LDCM0240  AC122 HEK-293T C51(0.51)  LDD0838  [2]
 LDCM0241  AC123 HEK-293T C51(0.51)  LDD0839  [2]
 LDCM0242  AC124 HEK-293T C51(0.77)  LDD0840  [2]
 LDCM0243  AC125 HEK-293T C51(0.62)  LDD0841  [2]
 LDCM0244  AC126 HEK-293T C51(0.47)  LDD0842  [2]
 LDCM0245  AC127 HEK-293T C51(0.50)  LDD0843  [2]
 LDCM0246  AC128 HEK-293T C51(0.62)  LDD0844  [2]
 LDCM0247  AC129 HEK-293T C51(0.59)  LDD0845  [2]
 LDCM0249  AC130 HEK-293T C51(0.50)  LDD0847  [2]
 LDCM0250  AC131 HEK-293T C51(0.64)  LDD0848  [2]
 LDCM0251  AC132 HEK-293T C51(0.61)  LDD0849  [2]
 LDCM0252  AC133 HEK-293T C51(0.37)  LDD0850  [2]
 LDCM0253  AC134 HEK-293T C51(0.48)  LDD0851  [2]
 LDCM0254  AC135 HEK-293T C51(0.50)  LDD0852  [2]
 LDCM0255  AC136 HEK-293T C51(0.49)  LDD0853  [2]
 LDCM0256  AC137 HEK-293T C51(0.41)  LDD0854  [2]
 LDCM0257  AC138 HEK-293T C51(0.33)  LDD0855  [2]
 LDCM0258  AC139 HEK-293T C51(0.35)  LDD0856  [2]
 LDCM0259  AC14 PaTu 8988t C51(1.11)  LDD1138  [2]
 LDCM0260  AC140 HEK-293T C51(0.48)  LDD0858  [2]
 LDCM0261  AC141 HEK-293T C51(0.41)  LDD0859  [2]
 LDCM0262  AC142 HEK-293T C51(0.41)  LDD0860  [2]
 LDCM0263  AC143 HCT 116 C51(0.85)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C51(0.72)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C51(0.60)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C51(0.93)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C51(0.64)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C51(0.64)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C51(0.66)  LDD0586  [2]
 LDCM0270  AC15 PaTu 8988t C51(0.87)  LDD1149  [2]
 LDCM0271  AC150 HCT 116 C51(0.79)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C51(0.69)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C51(0.63)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C51(0.50)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C51(1.06)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C51(0.87)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C51(0.76)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C51(0.84)  LDD2161  [2]
 LDCM0276  AC17 HEK-293T C51(1.12)  LDD1515  [7]
 LDCM0277  AC18 HEK-293T C51(0.84)  LDD1516  [7]
 LDCM0278  AC19 HEK-293T C51(1.65)  LDD1517  [7]
 LDCM0279  AC2 HEK-293T C51(0.88)  LDD0877  [2]
 LDCM0282  AC22 HEK-293T C51(1.00)  LDD1521  [7]
 LDCM0284  AC24 HEK-293T C51(1.40)  LDD1523  [7]
 LDCM0285  AC25 HCT 116 C51(0.90)  LDD0602  [2]
 LDCM0286  AC26 HCT 116 C51(0.78)  LDD0603  [2]
 LDCM0287  AC27 HCT 116 C51(0.86)  LDD0604  [2]
 LDCM0288  AC28 HCT 116 C51(0.78)  LDD0605  [2]
 LDCM0289  AC29 HCT 116 C51(0.96)  LDD0606  [2]
 LDCM0290  AC3 HEK-293T C51(1.35)  LDD0888  [2]
 LDCM0291  AC30 HCT 116 C51(0.76)  LDD0608  [2]
 LDCM0292  AC31 HCT 116 C51(0.81)  LDD0609  [2]
 LDCM0293  AC32 HCT 116 C51(0.70)  LDD0610  [2]
 LDCM0294  AC33 HCT 116 C51(0.83)  LDD0611  [2]
 LDCM0295  AC34 HCT 116 C51(0.77)  LDD0612  [2]
 LDCM0296  AC35 HCT 116 C51(1.07)  LDD0613  [2]
 LDCM0297  AC36 HCT 116 C51(0.85)  LDD0614  [2]
 LDCM0298  AC37 HCT 116 C51(1.10)  LDD0615  [2]
 LDCM0299  AC38 HCT 116 C51(0.90)  LDD0616  [2]
 LDCM0300  AC39 HCT 116 C51(0.85)  LDD0617  [2]
 LDCM0301  AC4 HEK-293T C51(1.02)  LDD0899  [2]
 LDCM0302  AC40 HCT 116 C51(0.65)  LDD0619  [2]
 LDCM0303  AC41 HCT 116 C51(0.72)  LDD0620  [2]
 LDCM0304  AC42 HCT 116 C51(0.79)  LDD0621  [2]
 LDCM0305  AC43 HCT 116 C51(0.77)  LDD0622  [2]
 LDCM0306  AC44 HCT 116 C51(0.86)  LDD0623  [2]
 LDCM0307  AC45 HCT 116 C51(0.72)  LDD0624  [2]
 LDCM0308  AC46 HCT 116 C51(1.04)  LDD0625  [2]
 LDCM0309  AC47 HCT 116 C51(0.88)  LDD0626  [2]
 LDCM0310  AC48 HCT 116 C51(0.81)  LDD0627  [2]
 LDCM0311  AC49 HCT 116 C51(0.75)  LDD0628  [2]
 LDCM0312  AC5 HEK-293T C51(1.21)  LDD0910  [2]
 LDCM0313  AC50 HCT 116 C51(0.72)  LDD0630  [2]
 LDCM0314  AC51 HCT 116 C51(0.99)  LDD0631  [2]
 LDCM0315  AC52 HCT 116 C51(0.85)  LDD0632  [2]
 LDCM0316  AC53 HCT 116 C51(0.80)  LDD0633  [2]
 LDCM0317  AC54 HCT 116 C51(0.80)  LDD0634  [2]
 LDCM0318  AC55 HCT 116 C51(0.73)  LDD0635  [2]
 LDCM0319  AC56 HCT 116 C51(0.75)  LDD0636  [2]
 LDCM0320  AC57 HCT 116 C51(0.51)  LDD0637  [2]
 LDCM0321  AC58 HCT 116 C51(0.54)  LDD0638  [2]
 LDCM0322  AC59 HCT 116 C51(0.64)  LDD0639  [2]
 LDCM0323  AC6 PaTu 8988t C51(0.74)  LDD1202  [2]
 LDCM0324  AC60 HCT 116 C51(0.66)  LDD0641  [2]
 LDCM0325  AC61 HCT 116 C51(0.70)  LDD0642  [2]
 LDCM0326  AC62 HCT 116 C51(0.53)  LDD0643  [2]
 LDCM0327  AC63 HCT 116 C51(0.59)  LDD0644  [2]
 LDCM0328  AC64 HCT 116 C51(0.57)  LDD0645  [2]
 LDCM0329  AC65 HCT 116 C51(0.70)  LDD0646  [2]
 LDCM0330  AC66 HCT 116 C51(0.68)  LDD0647  [2]
 LDCM0331  AC67 HCT 116 C51(0.48)  LDD0648  [2]
 LDCM0334  AC7 PaTu 8988t C51(0.87)  LDD1213  [2]
 LDCM0345  AC8 PaTu 8988t C51(0.56)  LDD1224  [2]
 LDCM0349  AC83 HCT 116 C51(0.58)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C51(0.70)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C51(0.70)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C51(0.71)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C51(0.97)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C51(0.70)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C51(0.65)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C51(1.09)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C51(0.64)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C51(0.65)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C51(0.78)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C51(0.71)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C51(0.73)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C51(0.69)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C51(0.58)  LDD0681  [2]
 LDCM0365  AC98 HEK-293T C51(1.54)  LDD0963  [2]
 LDCM0366  AC99 HEK-293T C51(1.26)  LDD0964  [2]
 LDCM0248  AKOS034007472 PaTu 8988t C51(0.92)  LDD1127  [2]
 LDCM0356  AKOS034007680 PaTu 8988t C51(1.04)  LDD1235  [2]
 LDCM0275  AKOS034007705 PaTu 8988t C51(0.84)  LDD1154  [2]
 LDCM0368  CL10 HEK-293T C51(1.12)  LDD1572  [7]
 LDCM0369  CL100 HEK-293T C51(1.07)  LDD0967  [2]
 LDCM0370  CL101 PaTu 8988t C51(0.71)  LDD1249  [2]
 LDCM0371  CL102 PaTu 8988t C51(0.72)  LDD1250  [2]
 LDCM0372  CL103 PaTu 8988t C51(0.65)  LDD1251  [2]
 LDCM0373  CL104 PaTu 8988t C51(0.72)  LDD1252  [2]
 LDCM0375  CL106 HEK-293T C51(0.77); C130(1.29)  LDD1579  [7]
 LDCM0376  CL107 HEK-293T C51(0.97); C130(0.64)  LDD1580  [7]
 LDCM0377  CL108 HEK-293T C51(1.13)  LDD1581  [7]
 LDCM0380  CL110 HEK-293T C51(0.92); C130(1.58)  LDD1584  [7]
 LDCM0381  CL111 HEK-293T C51(1.10); C130(0.81)  LDD1585  [7]
 LDCM0382  CL112 HCT 116 C51(1.00)  LDD0699  [2]
 LDCM0383  CL113 HCT 116 C51(0.72)  LDD0700  [2]
 LDCM0384  CL114 HCT 116 C51(0.96)  LDD0701  [2]
 LDCM0385  CL115 HCT 116 C51(1.05)  LDD0702  [2]
 LDCM0386  CL116 HCT 116 C51(0.95)  LDD0703  [2]
 LDCM0387  CL117 HCT 116 C51(0.63)  LDD0704  [2]
 LDCM0388  CL118 HCT 116 C51(0.81)  LDD0705  [2]
 LDCM0389  CL119 HCT 116 C51(0.88)  LDD0706  [2]
 LDCM0390  CL12 HEK-293T C51(0.90)  LDD1594  [7]
 LDCM0391  CL120 HCT 116 C51(0.90)  LDD0708  [2]
 LDCM0392  CL121 HCT 116 C51(0.85)  LDD0709  [2]
 LDCM0393  CL122 HCT 116 C51(0.87)  LDD0710  [2]
 LDCM0394  CL123 HCT 116 C51(0.87)  LDD0711  [2]
 LDCM0395  CL124 HCT 116 C51(0.77)  LDD0712  [2]
 LDCM0396  CL125 HCT 116 C51(0.79)  LDD0713  [2]
 LDCM0397  CL126 HCT 116 C51(0.85)  LDD0714  [2]
 LDCM0398  CL127 HCT 116 C51(0.79)  LDD0715  [2]
 LDCM0399  CL128 HCT 116 C51(0.65)  LDD0716  [2]
 LDCM0401  CL14 HEK-293T C51(0.95); C130(1.05)  LDD1605  [7]
 LDCM0402  CL15 HEK-293T C51(1.19); C130(0.76)  LDD1606  [7]
 LDCM0403  CL16 PaTu 8988t C51(0.62)  LDD1282  [2]
 LDCM0404  CL17 PaTu 8988t C51(0.80)  LDD1283  [2]
 LDCM0405  CL18 PaTu 8988t C51(0.70)  LDD1284  [2]
 LDCM0406  CL19 PaTu 8988t C51(0.50)  LDD1285  [2]
 LDCM0407  CL2 HEK-293T C51(0.73); C130(1.13)  LDD1611  [7]
 LDCM0408  CL20 PaTu 8988t C51(0.47)  LDD1287  [2]
 LDCM0409  CL21 PaTu 8988t C51(0.33)  LDD1288  [2]
 LDCM0410  CL22 PaTu 8988t C51(0.53)  LDD1289  [2]
 LDCM0411  CL23 PaTu 8988t C51(0.50)  LDD1290  [2]
 LDCM0412  CL24 PaTu 8988t C51(0.82)  LDD1291  [2]
 LDCM0413  CL25 PaTu 8988t C51(0.56)  LDD1292  [2]
 LDCM0414  CL26 PaTu 8988t C51(0.47)  LDD1293  [2]
 LDCM0415  CL27 PaTu 8988t C51(0.57)  LDD1294  [2]
 LDCM0416  CL28 PaTu 8988t C51(0.51)  LDD1295  [2]
 LDCM0417  CL29 PaTu 8988t C51(0.42)  LDD1296  [2]
 LDCM0418  CL3 HEK-293T C51(1.16); C130(0.80)  LDD1622  [7]
 LDCM0419  CL30 PaTu 8988t C51(0.68)  LDD1298  [2]
 LDCM0420  CL31 HEK-293T C51(1.04)  LDD1624  [7]
 LDCM0423  CL34 HEK-293T C51(1.00)  LDD1627  [7]
 LDCM0425  CL36 HEK-293T C51(1.31)  LDD1629  [7]
 LDCM0428  CL39 HEK-293T C51(0.96); C130(0.80)  LDD1632  [7]
 LDCM0429  CL4 HEK-293T C51(1.24)  LDD1633  [7]
 LDCM0430  CL40 HEK-293T C51(0.94)  LDD1634  [7]
 LDCM0431  CL41 HEK-293T C51(1.18)  LDD1635  [7]
 LDCM0432  CL42 HEK-293T C51(0.87)  LDD1636  [7]
 LDCM0433  CL43 HEK-293T C51(1.01)  LDD1637  [7]
 LDCM0436  CL46 HEK-293T C51(0.79)  LDD1034  [2]
 LDCM0437  CL47 HEK-293T C51(0.95)  LDD1035  [2]
 LDCM0438  CL48 HEK-293T C51(1.02)  LDD1036  [2]
 LDCM0439  CL49 HEK-293T C51(0.77)  LDD1037  [2]
 LDCM0440  CL5 HEK-293T C51(1.36)  LDD1644  [7]
 LDCM0441  CL50 HEK-293T C51(0.60)  LDD1039  [2]
 LDCM0442  CL51 HEK-293T C51(0.84)  LDD1040  [2]
 LDCM0443  CL52 HEK-293T C51(1.05)  LDD1041  [2]
 LDCM0444  CL53 HEK-293T C51(1.22)  LDD1042  [2]
 LDCM0445  CL54 HEK-293T C51(0.91)  LDD1043  [2]
 LDCM0446  CL55 HEK-293T C51(0.82)  LDD1044  [2]
 LDCM0447  CL56 HEK-293T C51(1.01)  LDD1045  [2]
 LDCM0448  CL57 HEK-293T C51(1.03)  LDD1046  [2]
 LDCM0449  CL58 HEK-293T C51(0.88)  LDD1047  [2]
 LDCM0450  CL59 HEK-293T C51(0.74)  LDD1048  [2]
 LDCM0451  CL6 HEK-293T C51(1.14)  LDD1654  [7]
 LDCM0452  CL60 HEK-293T C51(0.62)  LDD1050  [2]
 LDCM0453  CL61 PaTu 8988t C51(0.79)  LDD1332  [2]
 LDCM0454  CL62 PaTu 8988t C51(0.74)  LDD1333  [2]
 LDCM0455  CL63 PaTu 8988t C51(1.12)  LDD1334  [2]
 LDCM0456  CL64 PaTu 8988t C51(1.03)  LDD1335  [2]
 LDCM0457  CL65 PaTu 8988t C51(0.76)  LDD1336  [2]
 LDCM0458  CL66 PaTu 8988t C51(0.68)  LDD1337  [2]
 LDCM0459  CL67 PaTu 8988t C51(0.61)  LDD1338  [2]
 LDCM0460  CL68 PaTu 8988t C51(0.63)  LDD1339  [2]
 LDCM0461  CL69 PaTu 8988t C51(0.64)  LDD1340  [2]
 LDCM0462  CL7 HEK-293T C51(1.10)  LDD1665  [7]
 LDCM0463  CL70 PaTu 8988t C51(0.63)  LDD1342  [2]
 LDCM0464  CL71 PaTu 8988t C51(1.10)  LDD1343  [2]
 LDCM0465  CL72 PaTu 8988t C51(1.27)  LDD1344  [2]
 LDCM0466  CL73 PaTu 8988t C51(0.68)  LDD1345  [2]
 LDCM0467  CL74 PaTu 8988t C51(0.83)  LDD1346  [2]
 LDCM0469  CL76 PaTu 8988t C51(0.87)  LDD1348  [2]
 LDCM0470  CL77 PaTu 8988t C51(0.69)  LDD1349  [2]
 LDCM0471  CL78 PaTu 8988t C51(0.72)  LDD1350  [2]
 LDCM0472  CL79 PaTu 8988t C51(0.82)  LDD1351  [2]
 LDCM0474  CL80 PaTu 8988t C51(0.70)  LDD1353  [2]
 LDCM0475  CL81 PaTu 8988t C51(0.63)  LDD1354  [2]
 LDCM0476  CL82 PaTu 8988t C51(0.74)  LDD1355  [2]
 LDCM0477  CL83 PaTu 8988t C51(0.63)  LDD1356  [2]
 LDCM0478  CL84 PaTu 8988t C51(0.70)  LDD1357  [2]
 LDCM0479  CL85 PaTu 8988t C51(0.78)  LDD1358  [2]
 LDCM0480  CL86 PaTu 8988t C51(0.70)  LDD1359  [2]
 LDCM0481  CL87 PaTu 8988t C51(0.74)  LDD1360  [2]
 LDCM0482  CL88 PaTu 8988t C51(0.67)  LDD1361  [2]
 LDCM0483  CL89 PaTu 8988t C51(0.75)  LDD1362  [2]
 LDCM0485  CL90 PaTu 8988t C51(0.57)  LDD1364  [2]
 LDCM0486  CL91 HEK-293T C51(0.80)  LDD1084  [2]
 LDCM0487  CL92 HEK-293T C51(1.15)  LDD1085  [2]
 LDCM0488  CL93 HEK-293T C51(0.95)  LDD1086  [2]
 LDCM0489  CL94 HEK-293T C51(0.64)  LDD1087  [2]
 LDCM0490  CL95 HEK-293T C51(0.70)  LDD1088  [2]
 LDCM0491  CL96 HEK-293T C51(1.21)  LDD1089  [2]
 LDCM0492  CL97 HEK-293T C51(0.96)  LDD1090  [2]
 LDCM0493  CL98 HEK-293T C51(0.94)  LDD1091  [2]
 LDCM0494  CL99 HEK-293T C51(0.81)  LDD1092  [2]
 LDCM0495  E2913 HEK-293T C51(1.24); C130(0.69)  LDD1698  [7]
 LDCM0468  Fragment33 PaTu 8988t C51(0.69)  LDD1347  [2]
 LDCM0427  Fragment51 HEK-293T C51(0.75); C130(1.01)  LDD1631  [7]
 LDCM0022  KB02 T cell C130(20.00)  LDD1707  [8]
 LDCM0023  KB03 Daoy C51(2.70)  LDD2731  [9]
 LDCM0024  KB05 ONS-76 C51(2.22)  LDD3376  [9]
 LDCM0628  OTUB2-COV-1 HEK-293T C130(0.38)  LDD2207  [10]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cytochrome b-c1 complex subunit 1, mitochondrial (UQCRC1) Peptidase M16 family P31930
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
NKG2-D type II integral membrane protein (KLRK1) . P26718
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein c-Fos (FOS) BZIP family P01100

References

1 A chemical proteomics approach for global mapping of functional lysines on cell surface of living cell. Nat Commun. 2024 Apr 8;15(1):2997. doi: 10.1038/s41467-024-47033-w.
Mass spectrometry data entry: PXD042888
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
4 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
5 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
6 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
7 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
8 An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29.
9 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
10 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.