Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C301 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02359 | Heme oxygenase 1 (HMOX1) | 24.8 | ||||
| LDTP05758 | S-methyl-5'-thioadenosine phosphorylase (MTAP) | 11.6 | ||||
| LDTP12020 | Histone-lysine N-methyltransferase SMYD3 (SMYD3) | 9.6 | ||||
| LDTP06333 | Serum paraoxonase/arylesterase 2 (PON2) | 9.0 | ||||
| LDTP00988 | Protein O-GlcNAcase (OGA) | 7.8 | ||||
| LDTP15484 | Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) | 7.4 | ||||
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 7.4 | ||||
| LDTP02264 | Asparagine synthetase [glutamine-hydrolyzing] (ASNS) | 6.9 | ||||
| LDTP08790 | Mitochondrial cardiolipin hydrolase (PLD6) | 6.8 | ||||
| LDTP12013 | dCTP pyrophosphatase 1 (DCTPP1) | 6.7 | ||||
| LDTP01769 | Dihydrofolate reductase (DHFR) | 6.7 | ||||
| LDTP00907 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) | 6.7 | ||||
| LDTP08979 | Prostaglandin reductase 2 (PTGR2) | 6.1 | ||||
| LDTP02868 | Fumarylacetoacetase (FAH) | 6.1 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 6.0 | ||||
| LDTP04285 | Proteasome subunit beta type-2 (PSMB2) | 5.9 | ||||
| LDTP11127 | ADP-dependent glucokinase (ADPGK) | 5.7 | ||||
| LDTP01328 | CAAX prenyl protease 1 homolog (ZMPSTE24) | 5.0 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 15.2 | ||||
| LDTP05900 | Metaxin-1 (MTX1) | 10.5 | ||||
| LDTP03277 | ER lumen protein-retaining receptor 1 (KDELR1) | 9.7 | ||||
| LDTP08881 | Transmembrane protein 199 (TMEM199) | 9.1 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 8.5 | ||||
| LDTP06034 | Lysosome membrane protein 2 (SCARB2) | 6.9 | ||||
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 6.6 | ||||
| LDTP02724 | Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) | 6.5 | ||||
| LDTP07236 | Protein GPR107 (GPR107) | 5.9 | ||||
| LDTP01804 | ATP synthase subunit a (MT-ATP6) | 5.9 | ||||
| LDTP09547 | Scavenger receptor class B member 1 (SCARB1) | 5.9 | ||||
| LDTP04071 | Voltage-dependent anion-selective channel protein 2 (VDAC2) | 5.8 | ||||
| LDTP18153 | Major facilitator superfamily domain-containing protein 3 (MFSD3) | 5.6 | ||||
| LDTP06945 | Sigma intracellular receptor 2 (TMEM97) | 5.2 | ||||
| LDTP09180 | Zinc transporter 7 (SLC30A7) | 5.2 | ||||
| LDTP04033 | Translocon-associated protein subunit alpha (SSR1) | 5.1 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP12565 | Mitochondrial import receptor subunit TOM22 homolog (TOMM22) | 19.3 | ||||
| LDTP13828 | Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) | 9.6 | ||||
| LDTP11076 | Apolipoprotein L2 (APOL2) | 7.8 | ||||
| LDTP05160 | Nucleobindin-2 (NUCB2) | 6.4 | ||||
| LDTP04094 | Large proline-rich protein BAG6 (BAG6) | 5.7 | ||||
| LDTP15253 | HEAT repeat-containing protein 3 (HEATR3) | 5.5 | ||||
| LDTP15420 | Mitochondrial import receptor subunit TOM5 homolog (TOMM5) | 5.4 | ||||
| LDTP19372 | Tetratricopeptide repeat protein 38 (TTC38) | 5.4 | ||||
| LDTP16080 | Protein FAM114A2 (FAM114A2) | 5.3 | ||||
| LDTP03499 | Elongation factor 1-delta (EEF1D) | 5.1 | ||||