Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C417  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04689  Adenosine kinase (ADK) 27.9
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 15.8
 LDTP02375  Poly [ADP-ribose] polymerase 1 (PARP1) 8.6
Transporter and channel
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03777  Nuclear pore complex protein Nup214 (NUP214) 14.4
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 13.6
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 6.8
Other
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15057  TBC1 domain family member 9B (TBC1D9B) 13.9
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 13.8
 LDTP12775  GATOR2 complex protein MIOS (MIOS) 10.6
 LDTP10781  NudC domain-containing protein 1 (NUDCD1) 7.1

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587