Probe Name	C110					Probe Info
Probe concentration	Probe:50uM; negative probe:50uM
Criteria	Quantification: AfBPP Probe vs Negative Probe
Quantitative Method	TMT
In Vivo Experiment Model	Model Type			Living cell
	Derived Tissue			Peripheral blood
	Disease Model		Normal
	Model Name		Human normal cells (HEK-293T)
Note	Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Target ID	Target Name					Binding Ratio
LDTP03540	Heme oxygenase 2 (HMOX2)					13.7
LDTP04004	Lysosomal Pro-X carboxypeptidase (PRCP)					12.7
LDTP05862	NAD(P) transhydrogenase, mitochondrial (NNT)					10.1
LDTP06618	ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP)					8.8
LDTP01769	Dihydrofolate reductase (DHFR)					6.9
LDTP06375	Delta(24)-sterol reductase (DHCR24)					6.5
LDTP08476	5'-3' exonuclease PLD3 (PLD3)					6.1
LDTP03730	Sepiapterin reductase (SPR)					5.8
LDTP15988	Probable serine carboxypeptidase CPVL (CPVL)					5.2
LDTP02896	Sphingomyelin phosphodiesterase (SMPD1)					5.0

Target ID	Target Name					Binding Ratio
LDTP06945	Sigma intracellular receptor 2 (TMEM97)					13.0
LDTP18153	Major facilitator superfamily domain-containing protein 3 (MFSD3)					9.4
LDTP09547	Scavenger receptor class B member 1 (SCARB1)					7.4
LDTP06034	Lysosome membrane protein 2 (SCARB2)					7.2
LDTP01059	Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B)					6.8
LDTP03277	ER lumen protein-retaining receptor 1 (KDELR1)					6.7
LDTP10913	Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A)					5.1
LDTP00865	Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20)					5.0

Target ID	Target Name					Binding Ratio
LDTP03678	ER lumen protein-retaining receptor 2 (KDELR2)					5.7
LDTP13630	Neudesin (NENF)					5.0

1	Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26. Mass spectrometry data entry: PXD041587