General Information of Experiment

Probe Name C099  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 10 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 12.0
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 9.8
 LDTP00907  Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) 8.7
 LDTP03540  Heme oxygenase 2 (HMOX2) 7.5
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 7.5
 LDTP01241  Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) 7.0
 LDTP00697  Cytochrome b5 type B (CYB5B) 6.5
 LDTP04565  Methionine aminopeptidase 1 (METAP1) 5.7
 LDTP06617  Ceramide glucosyltransferase (UGCG) 4.9
 LDTP00832  NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) 4.9
Transporter and channel
Click to Show/Hide to Show 8 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 17.1
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 10.0
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 9.3
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 9.1
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 7.0
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 6.5
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 6.0
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 5.2
Other
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03678  ER lumen protein-retaining receptor 2 (KDELR2) 10.6
 LDTP05375  Nucleobindin-1 (NUCB1) 6.4
 LDTP11076  Apolipoprotein L2 (APOL2) 5.1

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587