Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C217 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP03257 | Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) | 18.8 | ||||
| LDTP09088 | Phospholipase A2 group XV (PLA2G15) | 18.1 | ||||
| LDTP01562 | Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) | 16.0 | ||||
| LDTP06333 | Serum paraoxonase/arylesterase 2 (PON2) | 15.8 | ||||
| LDTP01982 | NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) | 14.4 | ||||
| LDTP15988 | Probable serine carboxypeptidase CPVL (CPVL) | 11.5 | ||||
| LDTP05029 | Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) | 11.3 | ||||
| LDTP07831 | Transmembrane protein with metallophosphoesterase domain (TMPPE) | 11.2 | ||||
| LDTP14218 | Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) | 9.9 | ||||
| LDTP00988 | Protein O-GlcNAcase (OGA) | 9.2 | ||||
| LDTP15484 | Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) | 9.1 | ||||
| LDTP04712 | Puromycin-sensitive aminopeptidase (NPEPPS) | 7.5 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 6.9 | ||||
| LDTP14141 | Mannose-1-phosphate guanyltransferase beta (GMPPB) | 6.5 | ||||
| LDTP05758 | S-methyl-5'-thioadenosine phosphorylase (MTAP) | 6.2 | ||||
| LDTP06477 | Methylsterol monooxygenase 1 (MSMO1) | 6.0 | ||||
| LDTP00783 | Beta-1,4-glucuronyltransferase 1 (B4GAT1) | 5.8 | ||||
| LDTP02837 | Beta-galactosidase (GLB1) | 5.8 | ||||
| LDTP08455 | Palmitoyltransferase ZDHHC13 (ZDHHC13) | 5.7 | ||||
| LDTP03610 | Cytochrome b-c1 complex subunit 1, mitochondrial (UQCRC1) | 5.3 | ||||
| LDTP06648 | Lanosterol 14-alpha demethylase (CYP51A1) | 5.3 | ||||
| LDTP04285 | Proteasome subunit beta type-2 (PSMB2) | 5.3 | ||||
| LDTP12868 | Endoplasmic reticulum aminopeptidase 1 (ERAP1) | 5.0 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP07885 | Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) | 67.6 | ||||
| LDTP01804 | ATP synthase subunit a (MT-ATP6) | 33.4 | ||||
| LDTP07490 | Zinc transporter 6 (SLC30A6) | 19.0 | ||||
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 17.9 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 16.2 | ||||
| LDTP09547 | Scavenger receptor class B member 1 (SCARB1) | 12.7 | ||||
| LDTP17362 | Magnesium transporter NIPA3 (NIPAL1) | 10.6 | ||||
| LDTP06945 | Sigma intracellular receptor 2 (TMEM97) | 10.6 | ||||
| LDTP07236 | Protein GPR107 (GPR107) | 10.3 | ||||
| LDTP03104 | V-type proton ATPase subunit B, brain isoform (ATP6V1B2) | 9.4 | ||||
| LDTP15648 | BRI3-binding protein (BRI3BP) | 9.2 | ||||
| LDTP04071 | Voltage-dependent anion-selective channel protein 2 (VDAC2) | 7.8 | ||||
| LDTP08881 | Transmembrane protein 199 (TMEM199) | 7.7 | ||||
| LDTP11136 | Sugar transporter SWEET1 (SLC50A1) | 7.3 | ||||
| LDTP00592 | Surfeit locus protein 4 (SURF4) | 7.3 | ||||
| LDTP15948 | Transmembrane protein 126A (TMEM126A) | 7.1 | ||||
| LDTP14952 | Mpv17-like protein 2 (MPV17L2) | 7.0 | ||||
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 6.8 | ||||
| LDTP03277 | ER lumen protein-retaining receptor 1 (KDELR1) | 6.5 | ||||
| LDTP17641 | Solute carrier family 35 member F2 (SLC35F2) | 6.1 | ||||
| LDTP18448 | Transmembrane 9 superfamily member 3 (TM9SF3) | 6.0 | ||||
| LDTP00865 | Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) | 6.0 | ||||
| LDTP10958 | Sigma non-opioid intracellular receptor 1 (SIGMAR1) | 5.9 | ||||
| LDTP01671 | STARD3 N-terminal-like protein (STARD3NL) | 5.9 | ||||
| LDTP15481 | Transmembrane protein 87A (TMEM87A) | 5.6 | ||||
| LDTP18153 | Major facilitator superfamily domain-containing protein 3 (MFSD3) | 5.3 | ||||
| LDTP12207 | Putative divalent cation/proton antiporter TMEM165 (TMEM165) | 4.9 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP10849 | Regulator of microtubule dynamics protein 3 (RMDN3) | 26.9 | ||||
| LDTP15067 | Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) | 12.3 | ||||
| LDTP01075 | Protein CutA (CUTA) | 9.6 | ||||
| LDTP01652 | Centrosomal protein 43 (CEP43) | 9.4 | ||||
| LDTP00105 | Protein unc-119 homolog B (UNC119B) | 8.2 | ||||
| LDTP03678 | ER lumen protein-retaining receptor 2 (KDELR2) | 8.1 | ||||
| LDTP12565 | Mitochondrial import receptor subunit TOM22 homolog (TOMM22) | 7.7 | ||||
| LDTP00281 | Golgi integral membrane protein 4 (GOLIM4) | 6.7 | ||||
| LDTP10056 | Protein FAM162A (FAM162A) | 6.4 | ||||
| LDTP13902 | Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) | 5.6 | ||||
| LDTP19021 | EF-hand calcium-binding domain-containing protein 14 (EFCAB14) | 5.4 | ||||
| LDTP01522 | Reticulon-3 (RTN3) | 5.2 | ||||
| LDTP13828 | Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) | 5.0 | ||||
| LDTP05160 | Nucleobindin-2 (NUCB2) | 4.9 | ||||