Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C272 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP01562 | Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) | 32.2 | ||||
| LDTP03540 | Heme oxygenase 2 (HMOX2) | 20.4 | ||||
| LDTP03198 | Ferrochelatase, mitochondrial (FECH) | 11.9 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 10.9 | ||||
| LDTP02222 | Bifunctional glutamate/proline--tRNA ligase (EPRS1) | 8.9 | ||||
| LDTP02175 | Epoxide hydrolase 1 (EPHX1) | 7.3 | ||||
| LDTP06333 | Serum paraoxonase/arylesterase 2 (PON2) | 7.2 | ||||
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 7.0 | ||||
| LDTP01982 | NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) | 5.9 | ||||
| LDTP09088 | Phospholipase A2 group XV (PLA2G15) | 5.5 | ||||
| LDTP00497 | Cyclin-G-associated kinase (GAK) | 5.4 | ||||
| LDTP10215 | Carboxymethylenebutenolidase homolog (CMBL) | 5.2 | ||||
| LDTP00907 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) | 5.2 | ||||
| LDTP02254 | ATP-dependent translocase ABCB1 (ABCB1) | 5.1 | ||||
| LDTP00988 | Protein O-GlcNAcase (OGA) | 5.0 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP03277 | ER lumen protein-retaining receptor 1 (KDELR1) | 14.2 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 8.1 | ||||
| LDTP17362 | Magnesium transporter NIPA3 (NIPAL1) | 7.8 | ||||
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 7.1 | ||||
| LDTP04071 | Voltage-dependent anion-selective channel protein 2 (VDAC2) | 7.0 | ||||
| LDTP05900 | Metaxin-1 (MTX1) | 6.9 | ||||
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 6.4 | ||||
| LDTP07885 | Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) | 5.8 | ||||
| LDTP09547 | Scavenger receptor class B member 1 (SCARB1) | 5.7 | ||||
| LDTP11813 | Solute carrier family 25 member 32 (SLC25A32) | 5.5 | ||||
| LDTP11095 | Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) | 5.5 | ||||
| LDTP12383 | Protein GPR108 (GPR108) | 5.4 | ||||
| LDTP20002 | Transmembrane protein 160 (TMEM160) | 5.3 | ||||
| LDTP01217 | Metaxin-2 (MTX2) | 5.2 | ||||
| LDTP00865 | Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) | 5.2 | ||||
| LDTP10958 | Sigma non-opioid intracellular receptor 1 (SIGMAR1) | 5.2 | ||||
| LDTP00562 | Membrane-associated progesterone receptor component 2 (PGRMC2) | 5.1 | ||||
| LDTP17641 | Solute carrier family 35 member F2 (SLC35F2) | 5.0 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP14792 | Small ribosomal subunit protein uS9m (MRPS9) | 12.3 | ||||
| LDTP18883 | Protein CEBPZOS (CEBPZOS) | 7.0 | ||||
| LDTP08364 | Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) | 6.7 | ||||
| LDTP03678 | ER lumen protein-retaining receptor 2 (KDELR2) | 6.6 | ||||
| LDTP12565 | Mitochondrial import receptor subunit TOM22 homolog (TOMM22) | 6.5 | ||||
| LDTP01652 | Centrosomal protein 43 (CEP43) | 6.5 | ||||
| LDTP15623 | Neuferricin (CYB5D2) | 6.0 | ||||
| LDTP13630 | Neudesin (NENF) | 5.8 | ||||
| LDTP14458 | Tetraspanin-6 (TSPAN6) | 5.5 | ||||
| LDTP14058 | Rap guanine nucleotide exchange factor 2 (RAPGEF2) | 5.0 | ||||