General Information of Experiment

Probe Name C418  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 6 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 43.4
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 42.2
 LDTP06384  Ribosomal protein S6 kinase alpha-1 (RPS6KA1) 24.4
 LDTP03540  Heme oxygenase 2 (HMOX2) 21.0
 LDTP08476  5'-3' exonuclease PLD3 (PLD3) 20.7
 LDTP04471  Ribosomal protein S6 kinase alpha-3 (RPS6KA3) 11.9
Transporter and channel
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 20.3
 LDTP07462  MFS-type transporter SLC18B1 (SLC18B1) 13.1
 LDTP17641  Solute carrier family 35 member F2 (SLC35F2) 11.2
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 8.3
Other
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP19372  Tetratricopeptide repeat protein 38 (TTC38) 12.5
 LDTP15714  Mdm2-binding protein (MTBP) 10.7
 LDTP13755  Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) 6.9

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587