Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C304 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP00907 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) | 13.5 | ||||
| LDTP06648 | Lanosterol 14-alpha demethylase (CYP51A1) | 10.9 | ||||
| LDTP01773 | Cytochrome c oxidase subunit 2 (MT-CO2) | 9.6 | ||||
| LDTP03842 | Squalene synthase (FDFT1) | 9.3 | ||||
| LDTP15484 | Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) | 8.8 | ||||
| LDTP02175 | Epoxide hydrolase 1 (EPHX1) | 8.3 | ||||
| LDTP00486 | Cytochrome b-c1 complex subunit 8 (UQCRQ) | 8.1 | ||||
| LDTP00325 | Pirin (PIR) | 7.8 | ||||
| LDTP08790 | Mitochondrial cardiolipin hydrolase (PLD6) | 7.1 | ||||
| LDTP00832 | NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) | 6.7 | ||||
| LDTP00697 | Cytochrome b5 type B (CYB5B) | 6.0 | ||||
| LDTP10550 | Dehydrogenase/reductase SDR family member 1 (DHRS1) | 6.0 | ||||
| LDTP00639 | ATP-binding cassette sub-family C member 4 (ABCC4) | 5.9 | ||||
| LDTP03481 | DNA-3-methyladenine glycosylase (MPG) | 5.9 | ||||
| LDTP06375 | Delta(24)-sterol reductase (DHCR24) | 5.7 | ||||
| LDTP06427 | Translin (TSN) | 5.5 | ||||
| LDTP11127 | ADP-dependent glucokinase (ADPGK) | 5.5 | ||||
| LDTP06986 | Rab-like protein 3 (RABL3) | 5.5 | ||||
| LDTP01803 | Adenosine deaminase (ADA) | 5.5 | ||||
| LDTP04565 | Methionine aminopeptidase 1 (METAP1) | 5.4 | ||||
| LDTP14276 | NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) | 5.4 | ||||
| LDTP13189 | Cytochrome b-c1 complex subunit 9 (UQCR10) | 5.4 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 30.1 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 17.6 | ||||
| LDTP10769 | Intermembrane lipid transfer protein VPS13A (VPS13A) | 14.5 | ||||
| LDTP08881 | Transmembrane protein 199 (TMEM199) | 13.2 | ||||
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 10.6 | ||||
| LDTP09547 | Scavenger receptor class B member 1 (SCARB1) | 10.4 | ||||
| LDTP04071 | Voltage-dependent anion-selective channel protein 2 (VDAC2) | 9.8 | ||||
| LDTP03277 | ER lumen protein-retaining receptor 1 (KDELR1) | 8.2 | ||||
| LDTP09180 | Zinc transporter 7 (SLC30A7) | 7.5 | ||||
| LDTP02724 | Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) | 6.5 | ||||
| LDTP20002 | Transmembrane protein 160 (TMEM160) | 6.3 | ||||
| LDTP14511 | ATP synthase subunit g, mitochondrial (ATP5MG) | 6.1 | ||||
| LDTP07236 | Protein GPR107 (GPR107) | 6.1 | ||||
| LDTP17641 | Solute carrier family 35 member F2 (SLC35F2) | 6.1 | ||||
| LDTP04033 | Translocon-associated protein subunit alpha (SSR1) | 5.9 | ||||
| LDTP06275 | Lysosomal-associated transmembrane protein 4A (LAPTM4A) | 5.5 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP11076 | Apolipoprotein L2 (APOL2) | 29.7 | ||||
| LDTP12565 | Mitochondrial import receptor subunit TOM22 homolog (TOMM22) | 22.6 | ||||
| LDTP14486 | Clustered mitochondria protein homolog (CLUH) | 7.2 | ||||
| LDTP08364 | Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) | 5.5 | ||||
| LDTP00281 | Golgi integral membrane protein 4 (GOLIM4) | 5.5 | ||||
| LDTP01522 | Reticulon-3 (RTN3) | 5.4 | ||||