General Information of Experiment

Probe Name C028  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 11 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12040  Prostaglandin E synthase 2 (PTGES2) 44.0
 LDTP05128  Glutathione S-transferase omega-1 (GSTO1) 42.5
 LDTP05850  Probable methyltransferase TARBP1 (TARBP1) 22.2
 LDTP06618  ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) 18.8
 LDTP11321  Acetyl-CoA acetyltransferase, cytosolic (ACAT2) 16.1
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 15.9
 LDTP03540  Heme oxygenase 2 (HMOX2) 9.7
 LDTP02359  Heme oxygenase 1 (HMOX1) 9.1
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 9.0
 LDTP06333  Serum paraoxonase/arylesterase 2 (PON2) 8.6
 LDTP01769  Dihydrofolate reductase (DHFR) 7.4
Transporter and channel
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP18153  Major facilitator superfamily domain-containing protein 3 (MFSD3) 7.9
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 7.9
Other
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00105  Protein unc-119 homolog B (UNC119B) 6.5

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587