Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C327 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP16007 | Lipid droplet-associated hydrolase (LDAH) | 13.3 | ||||
| LDTP05758 | S-methyl-5'-thioadenosine phosphorylase (MTAP) | 12.6 | ||||
| LDTP08728 | Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) | 10.1 | ||||
| LDTP06333 | Serum paraoxonase/arylesterase 2 (PON2) | 9.5 | ||||
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 9.3 | ||||
| LDTP02175 | Epoxide hydrolase 1 (EPHX1) | 7.9 | ||||
| LDTP01328 | CAAX prenyl protease 1 homolog (ZMPSTE24) | 7.8 | ||||
| LDTP01039 | Protein-S-isoprenylcysteine O-methyltransferase (ICMT) | 7.6 | ||||
| LDTP00907 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) | 7.0 | ||||
| LDTP02254 | ATP-dependent translocase ABCB1 (ABCB1) | 7.0 | ||||
| LDTP10329 | Ceramide synthase 2 (CERS2) | 7.0 | ||||
| LDTP03540 | Heme oxygenase 2 (HMOX2) | 6.9 | ||||
| LDTP03525 | Cell division cycle protein 27 homolog (CDC27) | 6.3 | ||||
| LDTP03374 | Peptidyl-prolyl cis-trans isomerase FKBP2 (FKBP2) | 6.1 | ||||
| LDTP09088 | Phospholipase A2 group XV (PLA2G15) | 5.9 | ||||
| LDTP06648 | Lanosterol 14-alpha demethylase (CYP51A1) | 5.9 | ||||
| LDTP00697 | Cytochrome b5 type B (CYB5B) | 5.7 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 5.5 | ||||
| LDTP04285 | Proteasome subunit beta type-2 (PSMB2) | 5.2 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 33.8 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 20.5 | ||||
| LDTP00262 | Acetyl-coenzyme A transporter 1 (SLC33A1) | 10.1 | ||||
| LDTP03277 | ER lumen protein-retaining receptor 1 (KDELR1) | 7.8 | ||||
| LDTP09547 | Scavenger receptor class B member 1 (SCARB1) | 7.4 | ||||
| LDTP00865 | Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) | 7.2 | ||||
| LDTP17641 | Solute carrier family 35 member F2 (SLC35F2) | 6.5 | ||||
| LDTP06945 | Sigma intracellular receptor 2 (TMEM97) | 6.5 | ||||
| LDTP15733 | Solute carrier family 25 member 44 (SLC25A44) | 6.1 | ||||
| LDTP15000 | Solute carrier family 35 member F1 (SLC35F1) | 6.1 | ||||
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 6.1 | ||||
| LDTP08881 | Transmembrane protein 199 (TMEM199) | 5.9 | ||||
| LDTP10958 | Sigma non-opioid intracellular receptor 1 (SIGMAR1) | 5.5 | ||||
| LDTP14952 | Mpv17-like protein 2 (MPV17L2) | 5.0 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP12565 | Mitochondrial import receptor subunit TOM22 homolog (TOMM22) | 14.2 | ||||
| LDTP14486 | Clustered mitochondria protein homolog (CLUH) | 12.6 | ||||
| LDTP13755 | Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) | 9.3 | ||||
| LDTP13630 | Neudesin (NENF) | 7.7 | ||||
| LDTP11076 | Apolipoprotein L2 (APOL2) | 7.2 | ||||
| LDTP00105 | Protein unc-119 homolog B (UNC119B) | 6.4 | ||||
| LDTP05160 | Nucleobindin-2 (NUCB2) | 5.4 | ||||
| LDTP08364 | Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) | 5.2 | ||||