Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C416 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP05758 | S-methyl-5'-thioadenosine phosphorylase (MTAP) | 18.4 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 9.0 | ||||
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 8.9 | ||||
| LDTP04712 | Puromycin-sensitive aminopeptidase (NPEPPS) | 6.4 | ||||
| LDTP03257 | Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) | 5.9 | ||||
| LDTP04375 | Methionine aminopeptidase 2 (METAP2) | 5.7 | ||||
| LDTP15484 | Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) | 5.7 | ||||
| LDTP01328 | CAAX prenyl protease 1 homolog (ZMPSTE24) | 5.5 | ||||
| LDTP00527 | Phosphoribosylformylglycinamidine synthase (PFAS) | 5.3 | ||||
| LDTP06648 | Lanosterol 14-alpha demethylase (CYP51A1) | 5.1 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 16.2 | ||||
| LDTP07885 | Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) | 16.1 | ||||
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 12.3 | ||||
| LDTP03277 | ER lumen protein-retaining receptor 1 (KDELR1) | 12.2 | ||||
| LDTP08881 | Transmembrane protein 199 (TMEM199) | 10.6 | ||||
| LDTP17641 | Solute carrier family 35 member F2 (SLC35F2) | 8.1 | ||||
| LDTP07462 | MFS-type transporter SLC18B1 (SLC18B1) | 7.7 | ||||
| LDTP14952 | Mpv17-like protein 2 (MPV17L2) | 7.0 | ||||
| LDTP00865 | Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) | 5.5 | ||||
| LDTP04592 | Monocarboxylate transporter 1 (SLC16A1) | 5.4 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP00105 | Protein unc-119 homolog B (UNC119B) | 16.7 | ||||
| LDTP13828 | Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) | 6.6 | ||||
| LDTP13755 | Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) | 5.6 | ||||
| LDTP08364 | Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) | 5.5 | ||||
| LDTP07934 | Synaptic vesicle glycoprotein 2A (SV2A) | 5.4 | ||||