General Information of Experiment

Probe Name C078  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 8 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15988  Probable serine carboxypeptidase CPVL (CPVL) 12.0
 LDTP03540  Heme oxygenase 2 (HMOX2) 10.9
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 9.4
 LDTP09256  Putative phospholipase B-like 2 (PLBD2) 5.4
 LDTP08979  Prostaglandin reductase 2 (PTGR2) 5.2
 LDTP01241  Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) 5.1
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 5.1
 LDTP02799  N-acetylglucosamine-6-sulfatase (GNS) 5.0
Transporter and channel
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 8.1
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 6.1
Other
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP13606  Mammalian ependymin-related protein 1 (EPDR1) 7.7
 LDTP11239  Protein misato homolog 1 (MSTO1) 6.3

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587