Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C333 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP12628 | Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) | 37.0 | ||||
| LDTP12363 | Lysophosphatidic acid phosphatase type 6 (ACP6) | 22.0 | ||||
| LDTP02175 | Epoxide hydrolase 1 (EPHX1) | 18.3 | ||||
| LDTP01039 | Protein-S-isoprenylcysteine O-methyltransferase (ICMT) | 15.7 | ||||
| LDTP11273 | N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) | 14.6 | ||||
| LDTP00907 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) | 14.2 | ||||
| LDTP03418 | Proteasome subunit beta type-6 (PSMB6) | 13.7 | ||||
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 12.6 | ||||
| LDTP04712 | Puromycin-sensitive aminopeptidase (NPEPPS) | 10.7 | ||||
| LDTP04285 | Proteasome subunit beta type-2 (PSMB2) | 9.7 | ||||
| LDTP06333 | Serum paraoxonase/arylesterase 2 (PON2) | 9.4 | ||||
| LDTP04253 | Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) | 8.9 | ||||
| LDTP08979 | Prostaglandin reductase 2 (PTGR2) | 7.8 | ||||
| LDTP15484 | Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) | 7.7 | ||||
| LDTP05758 | S-methyl-5'-thioadenosine phosphorylase (MTAP) | 7.3 | ||||
| LDTP03417 | Proteasome subunit beta type-4 (PSMB4) | 7.2 | ||||
| LDTP01769 | Dihydrofolate reductase (DHFR) | 6.4 | ||||
| LDTP06375 | Delta(24)-sterol reductase (DHCR24) | 6.2 | ||||
| LDTP02254 | ATP-dependent translocase ABCB1 (ABCB1) | 5.9 | ||||
| LDTP13358 | Leucyl-cystinyl aminopeptidase (LNPEP) | 5.9 | ||||
| LDTP00758 | Thioredoxin-like protein 1 (TXNL1) | 5.7 | ||||
| LDTP04246 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) | 5.6 | ||||
| LDTP07990 | Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) | 5.4 | ||||
| LDTP00697 | Cytochrome b5 type B (CYB5B) | 5.3 | ||||
| LDTP15422 | Prostaglandin reductase 3 (PTGR3) | 5.3 | ||||
| LDTP00832 | NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) | 5.2 | ||||
| LDTP06150 | DNA replication licensing factor MCM6 (MCM6) | 5.1 | ||||
| LDTP13751 | Exonuclease 1 (EXO1) | 5.1 | ||||
| LDTP16007 | Lipid droplet-associated hydrolase (LDAH) | 5.0 | ||||
| LDTP10329 | Ceramide synthase 2 (CERS2) | 4.9 | ||||
| LDTP11874 | Thioredoxin-related transmembrane protein 1 (TMX1) | 4.9 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 33.1 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 18.3 | ||||
| LDTP08881 | Transmembrane protein 199 (TMEM199) | 18.1 | ||||
| LDTP02724 | Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) | 15.7 | ||||
| LDTP03277 | ER lumen protein-retaining receptor 1 (KDELR1) | 10.0 | ||||
| LDTP14952 | Mpv17-like protein 2 (MPV17L2) | 9.7 | ||||
| LDTP15733 | Solute carrier family 25 member 44 (SLC25A44) | 8.8 | ||||
| LDTP15000 | Solute carrier family 35 member F1 (SLC35F1) | 8.6 | ||||
| LDTP09547 | Scavenger receptor class B member 1 (SCARB1) | 7.3 | ||||
| LDTP00262 | Acetyl-coenzyme A transporter 1 (SLC33A1) | 7.1 | ||||
| LDTP17362 | Magnesium transporter NIPA3 (NIPAL1) | 6.9 | ||||
| LDTP11813 | Solute carrier family 25 member 32 (SLC25A32) | 6.8 | ||||
| LDTP00865 | Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) | 6.7 | ||||
| LDTP17641 | Solute carrier family 35 member F2 (SLC35F2) | 6.1 | ||||
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 5.9 | ||||
| LDTP05900 | Metaxin-1 (MTX1) | 5.4 | ||||
| LDTP18459 | StAR-related lipid transfer protein 7, mitochondrial (STARD7) | 5.4 | ||||
| LDTP14511 | ATP synthase subunit g, mitochondrial (ATP5MG) | 5.4 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP03520 | Phosphatidylethanolamine-binding protein 1 (PEBP1) | 53.8 | ||||
| LDTP12565 | Mitochondrial import receptor subunit TOM22 homolog (TOMM22) | 12.7 | ||||
| LDTP11076 | Apolipoprotein L2 (APOL2) | 9.8 | ||||
| LDTP13828 | Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) | 9.1 | ||||
| LDTP14486 | Clustered mitochondria protein homolog (CLUH) | 7.2 | ||||
| LDTP15623 | Neuferricin (CYB5D2) | 7.0 | ||||
| LDTP04652 | Eukaryotic translation initiation factor 5 (EIF5) | 6.3 | ||||
| LDTP05375 | Nucleobindin-1 (NUCB1) | 6.1 | ||||
| LDTP05160 | Nucleobindin-2 (NUCB2) | 5.4 | ||||
| LDTP01075 | Protein CutA (CUTA) | 4.9 | ||||