Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C337 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP12013 | dCTP pyrophosphatase 1 (DCTPP1) | 17.1 | ||||
| LDTP04051 | Nicotinamide phosphoribosyltransferase (NAMPT) | 14.5 | ||||
| LDTP16007 | Lipid droplet-associated hydrolase (LDAH) | 9.1 | ||||
| LDTP00697 | Cytochrome b5 type B (CYB5B) | 7.0 | ||||
| LDTP11273 | N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) | 6.6 | ||||
| LDTP15422 | Prostaglandin reductase 3 (PTGR3) | 6.5 | ||||
| LDTP10032 | 7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) | 6.2 | ||||
| LDTP04285 | Proteasome subunit beta type-2 (PSMB2) | 6.1 | ||||
| LDTP13358 | Leucyl-cystinyl aminopeptidase (LNPEP) | 6.0 | ||||
| LDTP06645 | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) | 5.7 | ||||
| LDTP09043 | Lysine-specific histone demethylase 2 (KDM1B) | 5.7 | ||||
| LDTP04388 | Palmitoyl-protein thioesterase 1 (PPT1) | 5.4 | ||||
| LDTP12628 | Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) | 5.2 | ||||
| LDTP02837 | Beta-galactosidase (GLB1) | 5.1 | ||||
| LDTP12610 | Obg-like ATPase 1 (OLA1) | 5.0 | ||||
| LDTP05396 | Histone-lysine N-methyltransferase 2A (KMT2A) | 4.9 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 4.9 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 21.1 | ||||
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 11.8 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 11.3 | ||||
| LDTP02724 | Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) | 10.8 | ||||
| LDTP04071 | Voltage-dependent anion-selective channel protein 2 (VDAC2) | 9.1 | ||||
| LDTP14952 | Mpv17-like protein 2 (MPV17L2) | 7.7 | ||||
| LDTP06221 | StAR-related lipid transfer protein 3 (STARD3) | 6.4 | ||||
| LDTP11813 | Solute carrier family 25 member 32 (SLC25A32) | 6.2 | ||||
| LDTP03277 | ER lumen protein-retaining receptor 1 (KDELR1) | 5.9 | ||||
| LDTP09968 | V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) | 5.3 | ||||
| LDTP09949 | Transportin-1 (TNPO1) | 5.2 | ||||
| LDTP09547 | Scavenger receptor class B member 1 (SCARB1) | 5.1 | ||||
| LDTP11615 | Protein tweety homolog 3 (TTYH3) | 5.0 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP13828 | Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) | 15.7 | ||||
| LDTP03678 | ER lumen protein-retaining receptor 2 (KDELR2) | 15.3 | ||||
| LDTP03520 | Phosphatidylethanolamine-binding protein 1 (PEBP1) | 10.9 | ||||
| LDTP11076 | Apolipoprotein L2 (APOL2) | 9.4 | ||||
| LDTP01075 | Protein CutA (CUTA) | 7.8 | ||||
| LDTP12565 | Mitochondrial import receptor subunit TOM22 homolog (TOMM22) | 6.8 | ||||
| LDTP19372 | Tetratricopeptide repeat protein 38 (TTC38) | 5.7 | ||||
| LDTP00105 | Protein unc-119 homolog B (UNC119B) | 5.5 | ||||
| LDTP14486 | Clustered mitochondria protein homolog (CLUH) | 5.1 | ||||
| LDTP09297 | Large ribosomal subunit protein mL64 (GADD45GIP1) | 5.0 | ||||