Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C086  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP09874  Endoplasmic reticulum protein SC65 (P3H4) 14.5
 LDTP13751  Exonuclease 1 (EXO1) 8.5
 LDTP03540  Heme oxygenase 2 (HMOX2) 6.3
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 5.8
 LDTP14141  Mannose-1-phosphate guanyltransferase beta (GMPPB) 5.1
Transporter and channel
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01804  ATP synthase subunit a (MT-ATP6) 6.5
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 5.5
Other
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 8.5
 LDTP04207  Heat shock 70 kDa protein 13 (HSPA13) 6.5
 LDTP14058  Rap guanine nucleotide exchange factor 2 (RAPGEF2) 6.0

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587